Owing to an error that was made during the production stages of the above review article, what was actually Fig. 2 was inadvertently duplicated on p. 7 as Fig. 9. Fig. 9 as it should have appeared in the review is shown below. The Editor apologizes to the authors for this error, and regrets any inconvenience caused to the readership. [the original article was published in Molecular Medicine Reports 24: Article no. 506, 2021; DOI: 10.3892/mmr.2021.12145].

Stem cells receive cues from their physical and mechanical microenvironment via mechanosensing and mechanotransduction. These cues affect proliferation, self‑renewal and differentiation into specific cell fates. A growing body of evidence suggests that yes‑associated protein (YAP) and transcriptional coactivator with PDZ‑binding motif (TAZ) mechanotransduction is key for driving stem cell behavior and regeneration via the Hippo and other signaling pathways. YAP/TAZ receive a range of physical cues, including extracellular matrix stiffness, cell geometry, flow shear stress and mechanical forces in the cytoskeleton, and translate them into cell‑specific transcriptional programs. However, the mechanism by which mechanical signals regulate YAP/TAZ activity in stem cells is not fully understand. The present review summarizes the current knowledge of the mechanisms involved in YAP/TAZ regulation on the physical and mechanical microenvironment, as well as its potential effects on stem cell differentiation.