■认知功能是学习能力的核心,问题解决,记住,并以快速和准确的方式使用信息,认知能力是沟通的基础,自主性,和生活质量。经颅电刺激(tES)是一种非常有前途的工具,可改善各种运动和认知功能。当作为直流刺激(经颅直流刺激;tDCS)应用于背外侧前额叶皮质(DLPFC)时,这种形式的神经刺激在减缓认知恶化和潜在增强认知功能的能力方面有不同的结果,需要进一步调查。本研究旨在全面调查阳极和阴极双极双半球tDCS对执行功能和工作记忆能力的影响。
■招募了72名健康的年轻人,每个参与者被随机分配到对照组(CON),安慰剂组(SHAM)或两个神经刺激组(Anodal;A-STIM和Cathodal;C-STIM)之一。所有参与者在30分钟刺激/假/控制方案之前和之后进行认知测试(Stroop&NBack)。
■总的来说,我们的研究结果进一步增加了证据,表明tDCS在增强认知功能方面可能不如在M1上应用时在增强运动学习方面有效.我们还提供证据表明,神经刺激对认知功能的影响可能由性别调节,男性在考虑Stroop任务中简单注意力试验类型的表现时,从阳极和阴极刺激中获益。
■考虑到这一发现,我们提出了tDCS研究的新途径,性可能会降低神经刺激对认知功能的功效。
UNASSIGNED: Cognitive functioning is central to the ability to learn, problem solve, remember, and use information in a rapid and accurate manner and cognitive abilities are fundamental for communication, autonomy, and quality of life. Transcranial electric stimulation (tES) is a very promising tool shown to improve various motor and cognitive functions. When applied as a direct current stimulus (transcranial direct current stimulation; tDCS) over the dorsolateral pre-frontal cortex (DLPFC), this form of neurostimulation has mixed results regarding its ability to slow cognitive deterioration and potentially enhance cognitive functioning, requiring further investigation. This study set out to comprehensively investigate the effect that anodal and cathodal bipolar bihemispheric tDCS have on executive function and working memory abilities.
UNASSIGNED: 72 healthy young adults were recruited, and each participant was randomly allocated to either a control group (CON), a placebo group (SHAM) or one of two neurostimulation groups (Anodal; A-STIM and Cathodal; C-STIM). All participants undertook cognitive tests (Stroop & N Back) before and after a 30-minute stimulation/ sham/ control protocol.
UNASSIGNED: Overall, our results add further evidence that tDCS may not be as efficacious for enhancing cognitive functioning as it has been shown to be for enhancing motor learning when applied over M1. We also provide evidence that the effect of neurostimulation on cognitive functioning may be moderated by sex, with males demonstrating a benefit from both anodal and cathodal stimulation when considering performance on simple attention trial types within the Stroop task.
UNASSIGNED: Considering this finding, we propose a new avenue for tDCS research, that the potential that sex may moderate the efficacy of neurostimulation on cognitive functioning.