warm season

  • 文章类型: Journal Article
    这篇文章,基于OMI数据产品,利用空间分布,臭氧敏感控制区,皮尔逊相关方法,和Ben-MAP模型,研究2018-2022年臭氧柱浓度的变化,以及影响因素和暴露于臭氧的人群的健康。研究结果表明,研究区域内臭氧柱浓度存在空间变化,从西到东,从南到北都有增加的趋势。随着时间的推移,臭氧柱浓度表现出最初的增加,然后是随后的减少,2019年的峰值浓度为37.45DU,2022年的最低点为33.10DU。月均值分布在4月至9月的暖季呈现倒V型,7月为高峰(46.71DU),4月为低谷(35.29DU)。河套平原绿洲区主要是敏感控制区中的NOx控制区。O3和前驱体HCHO的浓度与植被指数和气温呈显著正相关,与风速和气压呈显著负相关。相反,前体NO2,植被指数和相对湿度均呈显著负相关。根据地面监测点和对人类健康益处的分析,研究区域在2018年有1944.45例死亡归因于暖季O3暴露,与基线年相比,2019年至2021年的过早死亡分别减少了149.7,588.2和231.75.2021年,与2018年相比,该地区暖季O3浓度下降导致显著下降,导致预防126例过早死亡。
    This article, based on OMI data products, utilizes spatial distribution, ozone-sensitive control areas, Pearson correlation methods, and the Ben-MAP model to study the changes in ozone column concentration from 2018 to 2022, along with the influencing factors and the health of populations exposed to ozone. The findings suggest a spatial variation in the ozone column concentration within the study area, with an increasing trend observed from west to east and from south to north. Over time, the ozone column concentration exhibits an initial increase followed by a subsequent decrease, with the peak concentration observed in 2019 at 37.45 DU and the nadir recorded in 2022 at 33.10 DU. The monthly mean distribution exhibits an inverted V-shaped pattern during the warm season from April to September, with a peak in July (46.71 DU) and a trough in April (35.29 DU). The Hetao Plain Oasis area is primarily a NOx control area in sensitive control areas. The concentrations of O3 and precursor HCHO exhibited significant positive correlations with vegetation index and air temperature, while showing significant negative correlations with wind speed and air pressure. The precursor NO2, in contrast, exhibited a significant negative correlation with both the vegetation index and relative humidity. Based on the ground-based monitoring sites and analysis of human health benefits, the study area witnessed 1944.45 deaths attributed to warm season O3 exposure in 2018, with a subsequent reduction in premature deaths by 149.7, 588.2, and 231.75 for the years 2019 to 2021 respectively when compared to the baseline year. In 2021, the observed decrease in warm-season O3 concentration within that region compared to 2018 resulted in a significant reduction, leading to the prevention of 126 premature deaths.
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  • 文章类型: Journal Article
    为了解暖季城市冠层以上大气污染特征,基于北京325m气象塔的高空观测,研究了亚微米气溶胶(PM1)的特征。260米的PM1在2015年5月、2015年6月和2017年6月分别为34、29和21μgm-3,表明城市冠层上方的PM1污染减少。同时,所有PM1化学物质(不包括Chl和BC)和有机气溶胶(OA)因子的浓度也出现总体下降.北京以前的重度雾霾通常与高湿度和停滞的天气条件相吻合。然而,2017年6月的污染事件加剧伴随着高风速和低相对湿度。与2015年5月相比,2017年6月次级组分对PM1的贡献更为突出,与SNA的总比例(硫酸盐,硝酸盐,和铵)和更多氧化的含氧OA(MO-OOA)对PM1的增加约10%。NH4NO3,(NH4)2SO4和MO-OOA的次生物种,以及黑碳,集体贡献了绝大多数的气溶胶消光系数(bext),这四个物种在260m处对bext的贡献总计≥96%。类烃OA,烹饪OA,氧化较少的含氧OA经历了显著的减少,因此,必须继续强调控制本地来源以减少这三种气溶胶物种,并解决区域来源以进一步减少整体气溶胶物种。在污染较低的情况下,PM的日变化更平滑,它的污染源在区域上更加统一,这可能归因于空气污染中物理和化学过程的多样性和复杂性的降低。
    To understand the characteristics of atmospheric pollution above the urban canopy in warm seasons, the characteristics of sub-micron aerosol (PM1) was studied based on high-altitude observations at the Beijing 325 m meteorological tower. The PM1 at 260 m was 34, 29 and 21 μg m-3 in May 2015, June 2015, and June 2017, respectively, indicating a reduction in PM1 pollution above the urban canopy. Meanwhile, an overall decrease was also observed in the concentrations of all PM1 chemical species (excluding Chl and BC) and organic aerosol (OA) factors. Previous instances of heavy haze in Beijing often coincided with high humidity and stagnant weather conditions. However, the heightened pollution episodes in June 2017 were accompanied by high wind speeds and low relative humidity. Compared to May 2015, the contribution of secondary components to PM1 in June 2017 was more prominent, with the total proportion of SNA (sulfate, nitrate, and ammonium) and more-oxidized oxygenated OA (MO-OOA) to PM1 increased by approximately 10 %. Secondary species of NH4NO3, (NH4)2SO4, and MO-OOA, as well as black carbon, collectively contributed the vast majority of aerosol extinction coefficient (bext), with the four species contributing a total of ≥96 % to bext at 260 m. Hydrocarbon-like OA, cooking OA, and less-oxidized oxygenated OA have undergone significant reductions, so continued emphasis on controlling local sources to reduce these three aerosol species and addressing regional sources to further mitigate overall aerosol species is imperative. In lower pollution situation, the diurnal variation of PM was smoother, and its pollution sources were more regionally uniform, which might be attributed to the reduced diversity and complexity in the physical and chemical processes in air pollution.
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  • 文章类型: Journal Article
    死食昆虫物种在死亡调查中被广泛使用,主要用于估计最小的死后间隔。因为这些物种使用分解的有机物来喂养,产卵,和幼虫发育。发育阶段和演替定殖模式为更短或更长的死后时间间隔提供了重要信息。双翅目是从分解体中回收的主要类群。温度变化/季节性是影响这些物种存在时间和活动的主要因素。其他因素,比如地理位置,临死前的情况,和死因,可以影响食尸食性昆虫的存在和演替。因此,在死亡调查期间,每个地理区域都需要进行有关物种定殖模式的连续研究和信息,以用作参考数据。这项研究解决了为北达科他州收集法医昆虫学数据的需要,在2022年7月的第一份食尸食尸昆虫多样性报告中,使用猪尸体作为人类类似物。在实验期间,鉴定出双翅目和鞘翅目18种,有10个新的州记录,而Calliphoridae被发现是主要的家族。从暴露的猪尸体中获得的有关食性昆虫物种多样性和动力学的数据将加强北达科他州法医昆虫学的最新知识,并将作为大平原地区死亡调查期间使用的参考数据。
    Necrophagous insect species are widely used during death investigations primarily for the estimation of the minimum postmortem interval, since these species use decomposing organic matter for feeding, oviposition, and larval development. The development stages and successional colonization patterns provide important information for shorter or longer postmortem time intervals. Diptera species are the predominant taxa recovered from decomposed bodies. The temperature variance/seasonality is the main factor affecting the time presence and activity of these species. Other factors, such as geographical location, antemortem conditions, and cause of death, can influence the presence and succession of necrophagous entomofauna. Consequently, successional studies and information regarding species colonization patterns are needed for each geographical region to be used as reference data during death investigations. This study addressed the need to collect forensic entomological data for the State of North Dakota, within the first necrophagous entomofauna diversity report for the month of July 2022, using pig carcasses as human analogs. During the experimental period, 18 species of Diptera and Coleoptera were identified, with 10 new state records, while Calliphoridae was found to be the predominant family. The resulted data on necrophagous insect species diversity and dynamics from exposed pig carcasses will strengthen the current knowledge on forensic entomology in North Dakota and will serve as reference data to be used during death investigations in the Great Plains region.
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  • 文章类型: Journal Article
    目的:极端热暴露与多种疾病有关。然而,我们目前对极端热暴露对肾脏疾病的具体影响的了解有限.
    方法:病例交叉研究。
    方法:在纽约州确定了1,114,322例主要诊断为肾脏疾病的急诊科(ED)就诊,2005-2013年。
    方法:极端热暴露定义为在该县的研究期间,每日温度超过该月的第90百分位数温度。
    结果:主要诊断为肾脏疾病及其亚型的ED访视(ICD-9[国际疾病分类,第九次修订]代码580-599、788)。
    方法:使用条件逻辑回归模型将ED就诊日的极端热暴露与对照日的极端热暴露进行比较,控制湿度,空气污染物,和假期。在温暖季节(5月至9月)极端热暴露后一周(滞后0-6天)计算肾脏疾病的额外风险。我们还根据社会人口统计学特征对我们的估计进行了分层。
    结果:极端热暴露与肾脏疾病相关的ED就诊风险增加1.7%(滞后第0天)至3.1%(滞后第2天);随着前一周极端热暴露天数的增加,这种关联更强。与极端热暴露的关联持续了整整一周,并且在过渡月份中更强(即,5月和9月;超额利率从1.8%到5.1%不等),而不是夏季(6月到8月;超额利率从1.5%到2.7%不等)。与急性肾损伤相关的急诊就诊者的关联强度更大,肾结石,和尿路感染.年龄和性别可能会改变极端热暴露与ED就诊之间的关联。
    结论:个人暴露于热量-人们在外面多长时间或是否可以使用空调-是未知的。
    结论:极端热暴露与肾脏疾病ED就诊的剂量依赖性较大风险显著相关。
    Extreme heat exposure is associated with multiple diseases. However, our current understanding of the specific impact of extreme heat exposure on kidney disease is limited.
    Case-crossover study.
    1,114,322 emergency department (ED) visits with a principal diagnosis of kidney disease were identified in New York state, 2005-2013.
    Extreme heat exposure was defined as when the daily temperature exceeded the 90th percentile temperature of that month during the study period in the county.
    ED visits with a principal diagnosis of kidney disease and its subtypes (ICD-9 [International Classification of Diseases, Ninth Revision] codes 580-599, 788).
    Extreme heat exposure on the ED visit days was compared with extreme heat exposure on control days using a conditional logistic regression model, controlling for humidity, air pollutants, and holidays. The excess risk of kidney disease was calculated for a week (lag days 0-6) after extreme heat exposure during the warm season (May through September). We also stratified our estimates by sociodemographic characteristics.
    Extreme heat exposure was associated with a 1.7% (lag day 0) to 3.1% (lag day 2) higher risk of ED visits related to kidney disease; this association was stronger with a greater number of extreme heat exposure days in the previous week. The association with extreme heat exposure lasted for an entire week and was stronger in the transitional months (ie, May and September; excess rates ranged from 1.8% to 5.1%) rather than the summer months (June through August; excess rates ranged from 1.5% to 2.7%). The strength of association was greater among those with ED visits related to acute kidney injury, kidney stones, and urinary tract infections. Age and sex may modify the association between extreme heat exposure and ED visits.
    Individual exposure to heat-how long people were outside or whether they had access to air conditioning-was unknown.
    Extreme heat exposure was significantly associated with a dose-dependent greater risk of ED visits for kidney disease.
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  • 文章类型: Journal Article
    全球气候变化正在导致更高的环境温度和更频繁的热浪。迄今为止,环境极端高温对儿童发病率的影响尚未得到充分研究,尽管给予儿童的生理易感性,具有较小的体表质量比,和多年的气温上升-迫切需要更好的信息来告知公共卫生政策和临床方法。在这次审查中,我们的目标是(1)确定以前与极端高温相关的儿科发病结果,(2)确定可能使儿童更容易受到热相关结果的易感合并症,和(3)绘制当前可用文献的图谱。使用Arksey和O\'Malley框架IntJSocResMethodol8:19-32,(2015)对当前全文文献进行了范围审查。搜索术语(1)儿科人群,(2)热暴露,(3)环境条件,(4)将不良结局合并到全面的PubMed和Medline文献检索中。在确定的1753年出版物中,根据与美国城市人口相关的选择标准,最终选择了20项相关研究.大多数确定的研究支持高极端温度暴露与热相关疾病之间的正相关关系,脱水/电解质失衡,一般症状,腹泻和消化障碍,传染病/感染,哮喘/喘息,和伤害。大多数研究发现与肾脏疾病无关,心血管疾病,或糖尿病。其他呼吸系统疾病和心理健康/心理障碍的结果混合。很少有确定的研究检查了对先前存在的疾病的易感性;囊性纤维化是我们发现的唯一合并症。需要进一步的研究来了解极端高温与特定结果之间的联系的细微差别,特别是儿童年龄之间的联系如何变化。性别,种族/民族,社区特征,和其他预先存在的条件。
    Global climate change is leading to higher ambient temperatures and more frequent heatwaves. To date, impacts of ambient extreme heat on childhood morbidity have been understudied, although-given children\'s physiologic susceptibility, with smaller body surface-to-mass ratios, and many years of increasing temperatures ahead-there is an urgent need for better information to inform public health policies and clinical approaches. In this review, we aim to (1) identify pediatric morbidity outcomes previously associated with extreme heat, (2) to identify predisposing co-morbidities which may make children more susceptible to heat-related outcomes, and (3) to map the current body of available literature. A scoping review of the current full-text literature was conducted using the Arksey and O\'Malley framework Int J Soc Res Methodol 8:19-32, (2015). Search terms for (1) pediatric population, (2) heat exposures, (3) ambient conditions, and (4) adverse outcomes were combined into a comprehensive PubMed and Medline literature search. Of the 1753 publications identified, a total of 20 relevant studies were ultimately selected based on selection criteria of relevance to US urban populations. Most identified studies supported positive associations between high extreme temperature exposures and heat-related illness, dehydration/electrolyte imbalance, general symptoms, diarrhea and digestion disorders, infectious diseases/infections, asthma/wheeze, and injury. Most studies found no association with renal disease, cardiovascular diseases, or diabetes mellitus. Results were mixed for other respiratory diseases and mental health/psychological disorders. Very few of the identified studies examined susceptibility to pre-existing conditions; Cystic Fibrosis was the only co-morbidity for which we found significant evidence. Further research is needed to understand the nuances of associations between extreme heat and specific outcomes-particularly how associations may vary by child age, sex, race/ ethnicity, community characteristics, and other pre-existing conditions.
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  • 文章类型: Journal Article
    The current study aimed at molecular identification and comparing the diversity of arthropods communities between pig and sheep carcasses during the cold and warm season in KwaZulu-Natal province of South Africa. Adult arthropods found on and around the carcasses were collected using either fly traps or forceps. Molecular analyses confirmed the identification of twelve arthropod species collected from both sheep and pig carcasses during the cold season. Results showed that 11 of 12 arthropod species were common in both sheep and pig carcasses, with exception to Onthophagus vacca (Coleoptera: Scarabaeidae) (Linnaeus, 1767) and Atherigona soccata (Diptera: Muscidae) (Rondani, 1871) species which were unique to sheep and pig carcasses respectively. However, during the warm season, the sheep carcass attracted more arthropod (n = 13) species as compared to the pig carcass. The difference in the obtained arthropod was due to the presence of O. vacca which was also unique to the sheep carcass during this season. Furthermore, there was an addition of a beetle species Hycleus lunatus (Coleoptera: Meloidae) (Pallas, 1782), which was collected from both sheep and pig carcasses but unique to the warm season. The pig carcass attracted more dipteran flies during both warm (n = 1,519) and cold season (n = 779) as compared to sheep carcass during the warm (n = 511) and cold season (n = 229). In contrast, coleopterans were more abundant on the sheep carcass during the warm season (n = 391) and cold season (n = 135) as compared to the pig carcass in both warm season (n = 261) and cold season (n = 114). In overall, more flies and beetles were collected on both sheep and pig carcasses during the warm season, and this further highlight that temperature influenced the observed difference in the abundance of collected arthropod between seasons.
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  • 文章类型: Journal Article
    This study aimed to compare fungal contamination of poultry litter between warm and cold seasons. It was carried out in commercial production conditions over two five-week fattening periods: one in the summer (July-August) and one in the winter (December-January). Broilers were reared on a litter composed of chopped straw and sawdust. Litter fungal concentration and composition were investigated weekly, along with litter temperature, moisture, and pH. Litter concentration of total fungi increased over both fattening periods, with no differences in median concentrations between them. Season also had no effect on yeast, Aspergillus section Nigri, and Cladosporium, Fusarium, and Rhizopus spp. concentrations, while the Aspergillus section Flavi and Aspergillus spp. combined showed higher concentrations in the summer, and Mucor and Penicillium spp. in the winter. Total fungal concentration highly correlated with litter temperature, moisture, and pH, regardless of the season. Our findings can be useful in the assessment and control of potential harmful effect of fungi on the health of poultry and poultry farm workers.
    Cilj ovoga rada bio je usporediti onečišćenje stelje za perad gljivicama između toplog i hladnog razdoblja godine. Istraživanje je provedeno u komercijalnim uvjetima proizvodnje tijekom petotjednog tova pilića ljeti (srpanj – kolovoz) i zimi (prosinac – siječanj). Pilići su držani na stelji od sjeckane slame i piljevine. Koncentracija i sastav gljivica u stelji istraživani su tjedno, zajedno s temperaturom, vlagom i pH stelje. Ukupna koncentracija gljivica u stelji povećavala se tijekom tova u oba godišnja razdoblja, bez utvrđenih razlika u prosječnim koncentracijama između razdoblja. Razdoblje godine također nije imalo utjecaja na koncentracije kvasaca, aspergila iz sekcije Nigri te Cladosporium, Fusarium i Rhizopus spp., a koncentracije aspergila iz sekcije Flavi, kao i ukupnih aspergila u stelji bile su veće u ljetnom, a koncentracije Mucor i Penicillium spp. u zimskom razdoblju. Utvrđena je visoka pozitivna povezanost ukupne koncentracije gljivica s temperaturom, vlagom i pH stelje, neovisno o razdoblju godine. Dobiveni rezultati mogu biti korisni u procjeni i kontroli potencijalnoga štetnog učinka gljivica na zdravlje peradi i radnika na peradarskim farmama.
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  • 文章类型: Journal Article
    OBJECTIVE: The aim of this study was to examine the association between air temperature and incidence of acute coronary heart disease in Northeast China.
    METHODS: We obtained coronary heart disease (CHD) daily hospitalization data from January 2017 to June 2019, and collected meteorological data including average daily air temperature, air pressure, relative humidity, wind velocity, sunshine duration and water vapor pressure, for the same period. Totally, This study included data from 6775 patients with CHD.
    RESULTS: After adjusting for confounding factors, low air temperature was inversely associated with CHD. Additionally, in the warm season (April-September), the number of daily hospital admissions for CHD was higher (≥24.2°C) if the average daily air temperature was low (≤15.4°C).
    CONCLUSIONS: Low air temperature might be a risk factor for CHD among the elderly, especially in the warm season.
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  • 文章类型: Journal Article
    背景:选择最佳受孕季节是计划生育的一部分,因为它可以积极影响妊娠结局。出生缺陷婴儿每月数量的变化可能表明产前损害-死亡或畸形-与有害的季节性因素有关。我们论文的目的是寻找具有口面裂痕的新生儿数量的季节性差异,从而在受孕期间增加口面裂痕发展的风险。
    方法:在1964-2000年期间,捷克共和国波西米亚地区的平均每月活产数量在5619个新生儿中进行了比较,这些新生儿和对照组来自3,080,891个新生儿的出生数据。
    结果:对照组显示每月新生儿数量有规律的季节性变化:3月至5月出生的婴儿明显增多,10月至12月出生的婴儿减少。在口面裂的婴儿组中也发现了类似的自然季节性变化。然而,根据性别和裂隙类型对裂隙群进行细分后,与控件相比,1-3月新生儿唇裂女童数量和4-5月新生儿唇裂男童数量存在显著差异.
    结论:我们发现,与对照组相比,新出生的CL女孩和CP男孩的数量存在显着差异。其出生日期对应于4月至8月的受孕以及5月至10月的估计产前裂隙形成的关键时期。后一个时期包括温暖的季节,当各种有害的身体,化学和生物因素可能对孕妇起作用。这一发现应在怀孕计划中予以考虑。有必要进行进一步的研究,以调查温暖季节可能影响妊娠结局的假定伤害因素。
    BACKGROUND: Choosing the optimal season for conception is a part of family planning since it can positively influence the pregnancy outcome. Changes in the monthly number of infants born with a birth defect can signal prenatal damage - death or malformation - related to a harmful seasonal factor. The aim of our paper was to search for possible seasonal differences in the numbers of new-borns with an orofacial cleft and thus for a period of conception that can increase the risk of orofacial cleft development.
    METHODS: Mean monthly numbers of live births in the Bohemia region of the Czech Republic during the years 1964-2000 were compared within a group of 5619 new-borns with various types of orofacial clefts and the control group derived from natality data on 3,080,891 new-borns.
    RESULTS: The control group exhibited regular seasonal variation in the monthly numbers of new-borns: significantly more babies born during March-May and fewer babies born during October-December. Similar natural seasonal variation was also found in the group of babies with an orofacial cleft. However, after subdividing the cleft group according to gender and cleft type, in comparison to controls, significant differences appeared in the number of new-born girls with cleft lip during January-March and in the number of boys born with cleft palate in April - May.
    CONCLUSIONS: We found significant differences from controls in the number of new-born girls with CL and boys with CP, whose dates of birth correspond to conception from April to August and to the estimated prenatal critical period for cleft formation from May to October. The latter period includes the warm season, when various injurious physical, chemical and biological factors may act on a pregnant woman. This finding should be considered in pregnancy planning. Future studies are necessary to investigate the putative injurious factors during the warm season that can influence pregnancy outcome.
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  • 文章类型: Journal Article
    本实验的目的是评估在AI时用100μg促性腺激素释放激素(GnRH)处理的热应激条件下泌乳奶牛的每次AI(P/AI)和AI后孕酮(P4)浓度,AI后5d,或者两者兼而有之。来自两个牛群的泌乳荷斯坦奶牛在夏季被纳入研究。根据去除尾漆在发情期检测到的奶牛被分配到四种处理:(1)对照(CON=722);(2)AI时的GnRH处理(G0=739);(3)AI后5d的GnRH处理(G5=697);(4)AI和AI后5d的GnRH处理(G0G5=697)。在AI(研究d0)从奶牛亚组中收集血液样本,研究d5和12以确定P4浓度。在研究d36和94进行妊娠诊断。从最靠近牛群的气象站收集温度和相对湿度,并计算温度-湿度指数(THI)。研究招募期间的平均THI为83.8±0.1,研究d0时的THI在研究d36时倾向于(P=0.09)与P/AI相关,但在研究d94时与P/AI无关(P=0.33)。在AI使用GnRH治疗,AI后5d,或者两者兼而有之,在研究d36或94时不影响(P≥0.64)P/AI。一种互动,然而,在治疗和泌乳次数之间检测到(P=0.06)。观察到这种相互作用是因为,在≥第三泌乳奶牛中,在研究第36天,G0+G5(28.6%)和G5(25.3%)的P/AI高于CON奶牛(17.3%)。≥第三泌乳G0母牛的每AI妊娠与CON没有差异(P≥0.11),G5和G0+G5奶牛。在第一和第二泌乳奶牛的处理中没有检测到P/AI的差异。总的来说,在AI使用GnRH治疗,AI后5d,在研究d0、5或12时,或两者均与P4浓度无关(P=0.94).在研究第36天诊断怀孕的母牛中,第5天的孕酮浓度不受AI时GnRH处理的影响(P≥0.24),AI后5d,或者两者兼而有之,但是,与G0奶牛相比,在AI和AI后5d用GnRH处理的奶牛在第12天的孕酮浓度更高。在第三次或更长时间的泌乳奶牛暴露于热应激条件下,生育能力受损,在AI后5d用GnRH处理或AI和AI后5d联合处理GnRH后,P/AI可能会增加,因为早期胚胎损失减少。
    Objectives of this experiment were to evaluate pregnancy per AI (P/AI) and progesterone (P4) concentrations after AI of lactating dairy cows under heat stress conditions treated with 100 μg gonadotropin-releasing hormone (GnRH) at AI, 5 d after AI, or both. Lactating Holstein cows from two herds were enrolled in the study during summer. Cows detected in estrus based on tail paint removal were allocated to four treatments: (1) control (CON = 722); (2) GnRH treatment at AI (G0 = 739); (3) GnRH treatment 5 d post-AI (G5 = 697); or (4) GnRH treatment at AI and 5 d post-AI (G0+G5 = 697). Blood samples were collected from a subgroup of cows at AI (study d 0), study d 5 and 12 to determine P4 concentrations. Pregnancy diagnosis was conducted at study d 36 and 94. Temperature and relative humidity were collected from a meteorological station nearest the herds and temperature-humidity index (THI) was calculated. Average THI during study enrollment was 83.8 ± 0.1 and THI at study d 0 tended (P = 0.09) to be associated with P/AI at study d 36, but it was not (P = 0.33) associated with P/AI at study d 94. Treatment with GnRH at AI, 5 d after AI, or both, did not affect (P ≥ 0.64) P/AI at study d 36 or 94. An interaction, however, was detected (P = 0.06) between treatment and lactation number. Such an interaction was observed because, among ≥ third-lactation cows, P/AI was greater for G0+G5 (28.6%) and G5 (25.3%) than CON cows (17.3%) at study d 36. Pregnancy per AI of ≥ third-lactation G0 cows did not (P ≥ 0.11) differ from CON, G5, and G0+G5 cows. No differences in P/AI were detected among treatments in first- and second-lactation cows. Overall, treatments with GnRH at AI, 5 d after AI, or both were not (P = 0.94) associated with P4 concentrations on study d 0, 5 or 12. Among cows diagnosed pregnant at study d 36, progesterone concentration on d 5 was not affected (P ≥ 0.24) by treatments with GnRH at AI, 5 d after AI, or both, but progesterone concentration on d 12 was greater for cows treated with GnRH at AI and 5 d after AI compared with G0 cows. Lactating dairy cows in their third or greater lactation exposed to heat stress conditions with compromised fertility may have increased P/AI after treatment with GnRH 5 d after AI or the combined treatment of GnRH at AI and 5 d after AI because of reduced early embryonic loss.
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