BACKGROUND: Acanthosis nigricans (AN) is a common skin disease characterized by clear pigmented patches on the folds of the skin. However, the AN research field lacks scientific and comprehensive bibliometric analysis. This article aims to use bibliometric methods to summarize and visualize the distribution patterns, research hotspots, and development trends of AN literature.
METHODS: Literature from 1900 to 2024 was retrieved from the Web of Science Core Collection database through AN\'s thematic search. Using CiteSpace, VOSviewer, and Excel 2019, conduct a comprehensive analysis of the number of publications, countries/regions, institutions, authors, journals, highly cited literature, keywords, and so on, and sort out the hotspots and directions of AN.
RESULTS: From 1900 to 2024, 1675 publications were included in the bibliometric analysis, showing a steady annual increase in the number of publications. The United States leads in this research field, with the University of Texas System being a key research institution. The Journal of Clinical Endocrinology & Metabolism has the highest number of published papers. The most cited article is \"Syndromes of Insulin Resistance and Acanthosis Nigricans: Insulin-Receptor Disorders in Man\" (1976). The author Taylor, SI, has published the most papers. \"Acanthosis nigricans\" is the most frequently occurring keyword. The main research hotspots and frontier areas in AN research are as follows: (1) The relationship between AN and other diseases is a popular research topic; (2) The connection between AN and insulin resistance (IR) is a current research focus; (3) Treatment of AN, with an emphasis on addressing the underlying causes and improving local skin conditions, represents the cutting edge of this field.
CONCLUSIONS: This study summarizes the research trends and hotspots in the field of AN, offering valuable information and insights for scholars focused on AN scientific research, and providing a reference for future research directions.

UNASSIGNED: Radiation therapy has become an important treatment for many malignant tumours after surgery and for palliative tumour care. Although modern radiotherapy technology is constantly improving, radiation damage to normal tissues is often difficult to avoid, and radiation-induced skin injury (RSI) is a common complication, manifested as skin erythema, peeling, ulceration, and even bone and deep organ damage, seriously affect the quality of life for patients. Basic research and clinical trials related to RSI have achieved certain results, while no researchers have conducted comprehensive bibliometric studies.
UNASSIGNED: A comprehensive bibliometric analysis of publications on RSI published between 2004 and 2023 was conducted to identify current hotspots and future directions in this area of study.
UNASSIGNED: RSI-related publications published between January 1, 2004, and December 31, 2023, were retrieved from the Web of Science Core Collection (WoSCC) database for analysis using VOSviewer and CiteSpace analytics.
UNASSIGNED: A total of 1009 publications on RSI from 2004 to 2023 were included in the WoSCC database. The United States had the highest productivity with 299 papers, accounting for 29.63% of the total production, followed by China with 193 papers (19.13%) and Japan with 111 papers (11.00%). In terms of research institutions and journals, the University of Toronto and Journal of Supportive Care in Cancer published the highest number of papers. Professor Edward Chow published the most articles, while Professor Shuyu Zhang was the most cited. The top ten most-cited papers focused on the pathogenesis, prevention, and management of RSI. Keyword co-occurrence analysis and the top 25 keywords with the strongest citation bursts suggest that current research focuses on the pathogenesis, prevention, and treatment management of RSI.
UNASSIGNED: This study conducted a systematic bibliometric analysis of RSI publications from 2004 to 2023; identified the trends in RSI publications, major research countries, major research institutions, major research journals, major research authors, and major research keywords; and revealed the future development direction and research hotspots of this field. This study provides a valuable reference for future RSI research.

UNASSIGNED: The present study aims to conduct a comprehensive bibliometric analysis of global research in palliative care for cervical cancer, providing insights into publication trends, authorship patterns, influential journals, and thematic concentrations.
UNASSIGNED: A bibliometric analysis approach was employed using metadata extracted from Scopus spanning 2000-2023. The search utilized main terms related to cervical cancer and palliative care. Data analysis and visualization were performed using the Bibliometrix R Package\'s web app Biblioshiny and VOSviewer software.
UNASSIGNED: The study identified 2,492 publications on palliative care for cervical cancer, with a notable peak in 2021. The analysis revealed a diverse publication landscape, encompassing primarily articles. Citation analysis showed a staggering 63,994 citations. The most relevant journals were The Lancet Oncology, Gynecologic Oncology, and International Journal of Gynecological Cancer. The study also highlighted influential authors, institutions, and countries, with Harvard University, the University of Toronto, and the University of Texas MD Anderson Cancer Center leading in publications.
UNASSIGNED: The findings reflected a growing interest in palliative care for cervical cancer, marked by increasing publications over the years. However, the analysis indicated limited international collaborations, with research efforts concentrated in high-income countries. Thematic areas include surgery, palliative care, chemotherapy, radiotherapy, and quality of life. Thus, further collaborations and research in developing countries are needed.
UNASSIGNED: This bibliometric analysis showcased a comprehensive overview of the global research landscape on palliative care for cervical cancer. The study identified trends, key contributors, and thematic concentrations, offering valuable insights for future research directions and enhancing palliative care services. Addressing the identified gaps, fostering international collaborations, and directing research efforts toward developing countries can contribute to the advancement of palliative care for cervical cancer globally.

BACKGROUND: Seborrheic dermatitis (SD) is a common chronic inflammatory skin disease. In recent years, significant progress has been made in the field of SD, but there has been no bibliometric research yet. This study aims to use bibliometric methods to analyze the current research status and hot topics of SD, to understand further the research trends and future development prospects in this field.
METHODS: Retrieve core literature on SD from the Web of Science database and conduct a detailed analysis using CiteSpace and VOSviewer software based on factors such as publication volume, countries (regions), research institutions, journals, authors, highly-cited papers, and keywords.
RESULTS: From 1996 to 2024, a total of 1436 publications were included in the bibliometric analysis. The number of publications has shown an increasing trend year by year. The USA is the leading country in this field of research. The University of California System is the primary research institution. The International Journal of Dermatology is the journal with the highest number of publications. The author Yang Won Lee has the highest number of publications, while the article \"Seborrheic Dermatitis\" (2004) by Gupta, A.K. has been cited the most. \"Seborrheic dermatitis\" is the most frequently occurring keyword. The main research hotspots and frontiers in SD are as follows: (1) The relationship between SD and other skin diseases is a popular research topic; (2) Malassezia and inflammation are current research hotspots in SD; and (3) Focusing on antifungal and anti-inflammatory treatments for SD is the current frontier direction in this field.
CONCLUSIONS: This study is a summary of the current status and hot trends of SD research, which helps clinical doctors and researchers quickly understand the insights and valuable information of SD research and provides reference for clinical decision-making and finding future research directions.

BACKGROUND: Renal Denervation (RDN) is a novel non-pharmacological technique to treat hypertension. This technique lowers blood pressure by blocking the sympathetic nerve fibers around the renal artery, then causing a decrease in system sympathetic nerve excitability. This study aimed to visualize and analyze research hotspots and development trends in the field of RDN for hypertension through bibliometric analysis.
METHODS: In total, 1479 studies were retrieved on the Web of Science Core Collection (WoSCC) database from 2004 to 2023. Using CiteSpace (6.2.R4) and VOSviewer (1.6.18), visualization maps were generated by relevant literature in the field of RDN for hypertension to demonstrate the research status and frontiers.
RESULTS: The number of publications was found to be generally increasing. Europe and the United States were the first countries to carry out research on different techniques and related RDN clinical trials. The efficacy and safety of RDN have been repeatedly verified and gained increasing attention. The study involves multiple disciplines, including the cardiovascular system, peripheral vascular disease, and physiological pathology, among others. Research hotspots focus on elucidating the mechanism of RDN in the treatment of hypertension and the advantages of RDN in appliance therapy. Additionally, the research frontiers include improvement of RDN instruments and techniques, as well as exploration of the therapeutic effects of RDN in diseases with increased sympathetic nerve activity.
CONCLUSIONS: The research hotspots and frontiers reflect the status and development trend of RDN in hypertension. In the future, it is necessary to strengthen international collaboration and cooperation, conduct long-term clinical studies with a large sample size, and continuously improve RDN technology and devices. These measures will provide new options for more patients with hypertension, thereby improving their quality of life.

UNASSIGNED: Emergence agitation (EA) is a behavioural disturbance encountered during the recovery phase of patients following general anaesthesia. It is characterised by restlessness, involuntary limb movements, and drainage tube withdrawal and may significantly harm patients and medical staff. The mechanism of EA has not been fully understood and is still a challenging subject for researchers.
UNASSIGNED: We extracted relevant publications published between 1 January 2001 and 31 December 2023 on the Web of Science Core Collection platform. VOSviewer software was utilised to analyse the retrieved literature and predict the development trends and hotspots in the field.
UNASSIGNED: The results show that the number of publications grew annually, with China contributing the most, followed by the United States and South Korea. The co-occurrence of keywords \"children,\" \"propofol,\" \"risk factors\" are current research hotspots. Owing to its self-limiting and short-duration characteristics, EA lacks standardised clinical time guidelines and objective assessment tools, which may be the focus of future research in this field.
UNASSIGNED: Understanding the research hotspots and the latest progress in this field, this study will help to continuously improve the clinical understanding and management of EA, and help to timely identify environmental risk factors for EA in clinical practice.

Despite the increasing number of studies on nanomedicine-based cancer immunotherapy, the overall research trends in this field remain inadequately characterized. This study aims to evaluate the research trends and hotspots in nanomedicine-based cancer immunotherapy through a bibliometric analysis. As of March 31, 2024, relevant publications were retrieved from the Web of Science Core Collection. Analytical tools including VOSviewer, CiteSpace, and an online bibliometric analysis platform were employed. A total of 5,180 publications were analyzed. The study reveals geographical disparities in research output, with China and the United States being the leading contributors. Institutionally, the Chinese Academy of Sciences, University of Chinese Academy of Sciences, and Sichuan University are prominent contributors. Authorship analysis identifies key researchers, with Liu Zhuang being the most prolific author. \"ACS Nano\" and the \"Journal of Controlled Release and Biomaterials\" are identified as the leading journals in the field. Frequently occurring keywords include \"cancer immunotherapy\" and \"drug delivery.\" Emerging frontiers in the field, such as \"mRNA vaccine,\" \"sonodynamic therapy,\" \"oral squamous cell carcinoma,\" \"STING pathway,\"and \"cGAS-STING pathway,\" are experiencing rapid growth. This study aims to provide new insights to advance scientific research and clinical applications in nanomedicine-based cancer immunotherapy.

BACKGROUND: Spinal cord injury (SCI) is a debilitating condition with profound implications on patients\' quality of life (QOL). Recent advancements in brain-computer interface (BCI) technology have provided novel opportunities for individuals with paralysis due to SCI. Consequently, research on the application of BCI for treating SCI has received increasing attention from scholars worldwide. However, there is a lack of rigorous bibliometric studies on the evolution and trends in this field. Hence, the present study aimed to use bibliometric methods to investigate the current status and emerging trends in the field of applying BCI for treating SCI and thus identify novel therapeutic options for SCI.
METHODS: We conducted a comprehensive review of the relevant literature on BCI application for treating SCI published between 2005 and 2024 by using the Web of Science Core Collection (WoSCC) database. To facilitate visualization and quantitative analysis of the published literature, we used VOSviewer and CiteSpace software tools. These tools enabled the assessment of co-authorships, co-occurrences, citations, and co-citations in the selected literature, thereby providing an overview of the current trends and predictive insights into the field.
RESULTS: The literature search yielded 714 publications from the WoSCC database. The findings indicated a significant upward trend in the number of publications, yielding a total of 24,804 citations, with an average citation rate of 34.74 per publication and an H-index of 75. Research contributions were identified from 54 countries/regions, and the United States, China, and Germany emerged as the predominant contributors. A total of 1114 research institutions contributed to the retrieved literature, with Harvard Medical School, Brown University, and Northwestern University producing the highest number of publications. The published literature was predominantly distributed across 258 academic journals, and the Journal of Neural Engineering was the most frequently utilized publication source. Hochberg, Leigh, Henderson, Jaimie, and Collinger were the prominent authors in this field.
CONCLUSIONS: In recent years, there has been a steep increase in research on the use of BCI for treating SCI. Existing research focuses on the application of BCI for improving rehabilitation and QOL of patients with SCI. Interdisciplinary collaboration is the current trend in this field.

UNASSIGNED: Recent years have witnessed a rapid growth in research on accidental falls in patients with Parkinson\'s Disease (PD). However, a comprehensive and systematic bibliometric analysis is still lacking. This study aims to systematically analyze the current status and development trends of research related to accidental falls in patients with PD using bibliometric methods.
UNASSIGNED: We retrieved literature related to accidental falls in patients with PD published between January 1, 2003, and December 31, 2023, from the Web of Science Core Collection (WoSCC) database. Statistical analysis and knowledge mapping of the literature were conducted using VOSviewer, CiteSpace, and Microsoft Excel software.
UNASSIGNED: A total of 3,195 publications related to accidental falls in patients with PD were retrieved. These articles were authored by 13,202 researchers from 3,834 institutions across 87 countries and published in 200 academic journals. Over the past 20 years, the number of published articles and citations has increased annually. The United States and the United Kingdom have the highest number of publications in this field, while Harvard University and Tel Aviv University are the most influential institutions. The Parkinsonism & Related Disorders journal published the highest number of articles, while the Movement Disorders journal had the highest number of citations. The most prolific author is Bloem, Bastiaan R, while the most cited author is Hausdorff, Jeffrey. The main research areas of these publications are Neurosciences, Biomedical, Electrical & Electronic, and Biochemistry & Molecular Biology. Currently, high-frequency keywords related to accidental falls in patients with PD include risk factors, clinical manifestations, and interventions. Prediction and prevention of accidental falls in such patients is a research topic with significant potential and is currently a major focus of research.
UNASSIGNED: This study used bibliometric and knowledge mapping analysis to reveal the current research status and hotspots in the field of accidental falls in patients with PD. It also points out directions for future research. This study can provide theoretical support and practical guidance for scholars to further conduct related research.

The project aimed to conduct an up-to-date and comprehensive bibliometric analysis of robotic surgery to provide a detailed and holistic understanding of the field. Three strategies were employed in the data analysis i.e. search terms were explored in (A) the title, abstract, and keywords and (B) only in the title of the documents. In 3rd part we analyzed the top 100 most cited papers. Vosviewer and R Studio were utilized for detailed bibliometric and network analyses. Strategy one identified 38,469 publications, and strategy two identified 6451 publications from 2001 to 2023. The top authors, universities, countries, sponsors, and sources based on the number of publications were identified for both strategies. The top 100 most cited papers were analyzed, providing the annual number of publications and various citation metrics. Top authors (by number of publications, total citations, h-index, g-index, and m-index), universities, and countries within these highly cited papers, along with their co-authorship networks and dynamics, were examined. Co-words analysis of the top 100 most cited papers revealed the primary focus of these documents across 25 categories. This comprehensive bibliometric analysis of robotic surgery highlighted significant contributions and collaborations in the field, emphasizing the importance of global and collaborative efforts in advancing robotic surgery research.