背景:步态障碍在帕金森病(PD)患者中很常见,这大大降低了他们的生活质量。执行功能障碍与步态障碍有关。补偿策略,包括视觉线索,已被证明可有效改善PD步态。在这项研究中,我们的目的是了解带有视觉线索的地毯是否可以改善PD步态,以及不同执行功能状态的患者的改善情况如何。
方法:我们设计了带有棋盘和条纹提示的地毯。总共招募了65名中国PD患者。运动障碍协会统一帕金森病评定量表,左旋多巴等效日剂量,Hoehn&Yahr舞台,正面评估电池,迷你精神状态检查量表,汉密尔顿焦虑量表,评估汉密尔顿抑郁量表。步态参数,包括步幅长度,可穿戴电子设备记录步态速度和跌倒风险。
结果:当PD患者在带有棋盘和条纹图案的地毯上行走时,步幅和步态速度显着提高,跌倒风险显着减轻。进一步的分析表明,步态参数的改善与执行功能障碍无关。
结论:我们的研究表明,带视觉线索的地毯可以改善PD患者的步态,即使是轻度执行功能障碍的患者。
BACKGROUND: Gait impairment is common in Parkinson\'s disease (PD) patients, which greatly reduces their quality of life. Executive dysfunction is associated with gait impairment. Compensatory strategies, including visual cues, have been shown to be effective in improving PD gait. In this study, we aimed to understand whether carpets with visual cues could improve PD gait, and how the improvement varies across patients with different executive function state.
METHODS: We designed carpets with chessboard and stripe cues. A total of 65 Chinese PD patients were recruited. Movement Disorder Society Unified Parkinson\'s Disease Rating Scale, L-dopa equivalent daily dosage, Hoehn & Yahr stage, Frontal Assessment Battery, Mini Mental State Examination Scale, Hamilton Anxiety Scale, and Hamilton Depression Scale were evaluated. Gait parameters including stride length, gait speed and fall risk were recorded by a wearable electronic device.
RESULTS: The stride length and gait speed were significantly improved and the fall risk was significantly mitigated when PD patients walked on carpets with chessboard and stripe patterns. Further analysis showed the amelioration of gait parameters was independent of executive dysfunction.
CONCLUSIONS: Our study demonstrates that carpets with visual cues can improve the gait of PD patients even in those with mild executive dysfunction.