■鉴于机械循环支持在围手术期严重心功能不全患者中的作用,我们搜索了阜外医院机械循环支持的相关文章,分析不同机械循环支持方法的适应证及并发症。
■相关研究是通过PubMed的计算机化搜索确定的,奥维德,Embase,科克伦图书馆,万方数据,VIP数据,中国生物医学文献检索系统(SinoMed),和中国国家知识基础设施(CNKI),使用搜索词(\"主动脉内球囊反搏\"或\"IABP\"或\"体外膜氧合\"或\"ECMO\"或\"心室辅助装置\"或\"VAD\")和(\"Fuwai\"或\"fuwai\")。所有关于IABP应用的研究,ECMO,包括阜外医院的VAD,排除标准包括:(1)作为综述发表的研究,病例报告或摘要;(2)动物或细胞研究;(3)重复出版物;(4)缺乏有关感兴趣结果的信息的研究。
■共选择36篇文献进行分析。从研究中检索到的ECMO和VAD的特定机械循环支持方法是VA-ECMO和LVAD。使用IABP的病例数,ECMO,LVAD分别为1968、972、67;生存率为80.4%,54.9%,56.7%,分别。IABP的主要并发症,ECMO和LVAD均为出血(1.2%,35.9%和14.5%),感染(3.7%,12.7%和9.7%),急性肾损伤(9.1%,29.6%和6.5%),继发性并发症是肢体缺血,神经事件,心血管事件和血栓形成。
■本研究表明,IABP,ECMO和VAD,无论是单独还是组合,在阜外医院治疗严重血流动力学不稳定的心血管手术患者时,是有效和安全的机械循环支持。
UNASSIGNED: In view of the role of mechanical circulatory support in patients with severe cardiac insufficiency during perioperative period, we searched the relevant articles on mechanical circulatory support at Fuwai Hospital, and analyzed the indications and complications of different mechanical circulatory support methods.
UNASSIGNED: Relevant studies were identified by computerized searches of PubMed, Ovid, Embase, Cochrane Library, Wanfang Data, VIP Data, Chinese BioMedical Literature & Retrieval System (SinoMed), and China National Knowledge Infrastructure (CNKI), using search words (\"intra-aortic balloon counter pulsation\" OR \"IABP\" OR \"extracorporeal membrane oxygenation\" OR \"ECMO\" OR \"ventricular assist device\" OR \"VAD\") AND (\"Fuwai\" OR \"fuwai\"). All studies concerning the application of IABP, ECMO, and VAD at Fuwai Hospital were included, exclusion criteria included: (1) studies published as review, case report or abstract; (2) animal or cell studies; (3) duplicate publications; (4) studies lacking information about outcomes of interest.
UNASSIGNED: A total of 36 literatures were selected for analysis. The specific mechanical circulatory support methods of ECMO and VAD retrieved from the studies were VA-ECMO and LVAD. The number of cases using IABP, ECMO, LVAD was 1968, 972, 67; and the survival rate was 80.4%, 54.9%, 56.7%, respectively. The major complications of IABP, ECMO and LVAD were hemorrhage (1.2%, 35.9% and 14.5%), infection (3.7%, 12.7% and 9.7%), acute kidney injury (9.1%, 29.6% and 6.5%), the secondary complications were limb ischemia, neurological events, cardiovascular events and thrombosis.
UNASSIGNED: The present study suggested that, IABP, ECMO and VAD, either alone or in combination, were effective and safe mechanical circulation support when managing cardiovascular surgical patients with severe hemodynamic instability at Fuwai Hospital.