背景:外周插入的中央导管(PICC)和新型的手臂端口,PICC端口,目前用于乳腺癌患者的新辅助化疗治疗。我们旨在比较接受这两种设备之一的患者的生活质量(QoL)调查总体满意度,心理影响,以及对专业人士的影响,社会和体育活动,当地的不适。
方法:我们对PICC端口和PICC端口进行了前瞻性观察前后研究。纳入新辅助化疗的成年(年龄≥18岁)女性乳腺癌患者。主要结果是根据植入装置12个月后评估的生活质量评估静脉装置导管(QLAVD)问卷的QoL。
结果:在2019年5月至2020年11月之间,对278名个人进行了资格筛选,210人报名。PICC端口优于PICC,QLAVD评分分别为29[25;32]和31[26;36.5](p=0.014)。具体来说,大多数QLAVD结构与心理影响有关,社会方面,不适倾向于PICC端口与PICC,尤其是60岁以下的女性。总的来说,插入时和治疗期间的疼痛评分两组之间没有显着差异,以及感染,继发性错位,血栓形成,或设备的阻塞。
结论:在接受新辅助化疗的乳腺癌患者中,在QoL方面,PICC端口总体上比PICC更好地接受,尤其是那些年轻的人。器械相关并发症相似。
BACKGROUND: Peripherally inserted central catheters (PICCs) and new type of arm-port, the PICC-port, are currently used for neoadjuvant chemotherapy treatment in patients with breast cancer. We aimed to compare Quality of Life (QoL) of patients receiving one of these two devices investigating overall satisfaction, psychological impact, as well as the impact on professional, social and sport activities, and local discomfort.
METHODS: We did a prospective observational before-after study of PICCs versus PICC-ports. Adult (aged ≥ 18 years) females with breast cancer candidate to neoadjuvant chemotherapy were included. The primary outcome was QoL according to the Quality-of-Life Assessment Venous Device Catheters (QLAVD) questionnaire assessed 12 months after device implantation.
RESULTS: Between May 2019 and November 2020, of 278 individuals screened for eligibility, 210 were enrolled. PICC-ports were preferred over PICCs with a QLAVD score of 29 [25; 32] vs 31 [26; 36.5] (p = 0.014). Specifically, most QLAVD constructs related to psychological impact, social aspects, and discomfort were in favor of PICC-ports vs PICC, especially in women under the age of 60. Overall, pain scores at insertion and during therapy administration were not significantly different between the two groups, as well as infection, secondary malpositioning, thrombosis, or obstruction of the device.
CONCLUSIONS: In women with breast cancer undergoing neoadjuvant chemotherapy, PICC-ports were overall better accepted than PICCs in terms of QoL, especially in those who were younger. Device-related complications were similar.