目的:评估原发性单症状性夜间遗尿症(PMNE)患儿的经骶旁经皮神经电刺激(TENS)与尿路治疗相关的临床反应。
方法:这项前瞻性对照临床试验纳入了72名5岁以上的PMNE患儿。患儿随机分为两组,对照组(CG),用尿路疗法和肩胛骨刺激治疗,和实验组(EG),用尿路疗法和骶骨旁TENS治疗。在这两组中,进行了20次会议,每周3次,每个20分钟,频率为10Hz,由患者阈值确定的700μS脉冲宽度和肥胖。在治疗前(T0)分析14天的干燥夜晚百分比,在第20届会议(T1)之后,15(T2),30(T3),60(T4),以及会议结束后90(T5)天。两组患者均在第一个月间隔2周,连续三个月每月随访一次。
结果:28名儿童,平均年龄为9.09±2.23岁的14名女孩(50%)完成了研究。两组之间的平均年龄没有差异。T0时EG干夜的平均百分比为36%,在T149%,在T254%,在T354%,在T454%,T5时为57%;而在CG中,这些百分比是28%,39%,37%,35%,36%,36%,分别。
结论:与尿路治疗相关的骶旁TENS改善了PMNE患儿的干夜百分比,尽管在这项研究中没有患者症状完全缓解。
To evaluate the clinical response of parasacral transcutaneous electrical neural stimulation (parasacral TENS) associated with
urotherapy in children with primary monosymptomatic nocturnal enuresis (PMNE) compared to
urotherapy alone.
This prospective controlled clinical trial enrolled 72 children over 5 years of age with PMNE. Children were randomly divided into two groups, control group (CG), treated with
urotherapy and scapular stimulation, and experimental group (EG), treated with
urotherapy and parasacral TENS. In both groups, 20 sessions were performed, 3 times weekly, for 20 min each, with 10 Hz frequency, 700 μS pulse width and intesity determinated by the patient threshold. The percentages of dry nights were analyzed for 14 days before treatment (T0), after the 20th session (T1), 15 (T2), 30 (T3), 60 (T4), and 90 (T5) days after the end of the sessions. Patients of both groups were followed with intervals of 2 weeks in the first month and monthly for three consecutive months.
Twenty-eight enuretic children, 14 girls (50%) with a mean age of 9.09 ± 2.23 years completed the study. There was no difference in mean age between groups. Mean percentage of dry nights in EG at T0 was 36%, at T1 49%, at T2 54%, at T3 54%, at T4 54%, and 57% at T5; while in CG, these percentages were 28%, 39%, 37%, 35%, 36%, and 36%, respectively.
Parasacral TENS associated with
urotherapy improves the percentage of dry nights in children with PMNE, although no patient had complete resolution of symptoms in this study.