绿色指甲综合征(GNS)是指甲板绿色变色的三联征,近端甲沟炎,和远端甲状腺溶解症。铜绿假单胞菌是已知的最常见的病原体;然而,GNS的诊断和治疗没有统一的标准。因此,治疗是具有挑战性的,往往是难治的。这里,我们报告了三个具有不同诱发因素的代表性病例,包括与创伤有关的,职业相关,和与甲癣相关的GNS。指导GNS合并甲栓的患者进行化学指甲撕脱联合局部抗生素,所有病例均取得了良好的疗效。尿素粉末化学指甲撕脱作为常规方法可能是GNS的有效治疗方法,值得临床推广。
Green nail syndrome (GNS) is a triad of green discoloration of the nail plate, proximal paronychia, and distal onycholysis. Pseudomonas aeruginosa is known to be the most common causative agent; however, there is no unified standard for the diagnosis and treatment of GNS. Thus, treatment is challenging and often refractory. Here, we report three representative cases with different predisposing factors, including trauma-related, occupation-related, and onychosis-related GNS. Patients with GNS accompanied by onycholysis were instructed to undergo chemical nail avulsion combined with topical antibiotics, and favorable curative effects were observed in all cases. Chemical nail avulsion with urea powder as a conventional method may be an effective treatment for GNS and warrants clinical generalization.