■中性粒细胞-淋巴细胞比率(NLR)是全身性炎症反应的简单标记。本研究旨在评估入院当天NLR对上消化道出血(UGIB)患者预后的预测意义。这是一种普遍的医疗紧急情况。
■在2019年1月至2022年12月期间入住我们诊所的726例患者被诊断为UGIB,谁接受了必要的检查,包括在研究中。患者格拉斯哥-布拉特福德评分(GBS),全洛克尔评分(FRS),首次入院时计算NLR水平。结果定义为住院死亡率,需要输血,手术治疗和内镜治疗。使用NLR四分位数水平将患者分为四组,以比较其临床特征,格拉斯哥布拉特福德得分,完整的Rockall评分等级,和预后。次要,我们通过添加NLR来修改FRS和GBS,分别。我们使用受试者工作特征曲线下面积(AUROC)来评估NLR风险预测的准确性,NLR-GBS,和NLR-FRS改进模型。
■在726名患者中,6%在医院死亡,23.9%接受内镜介入治疗,4.8%接受手术治疗,46.4%接受输血治疗。多因素logistic回归分析显示,高水平的NLR是UGIB患者死亡的危险因素(p=0.028)。NLR,GBS,FRS,NLR-GBS,NLR-FRS在预测住院患者死亡率方面具有足够的准确性,内镜治疗,和输血治疗,差异有统计学意义(p<0.05)。在对不良后果的综合预测中,NLR-GBS具有最高的AUROC,在预测住院患者死亡率时,NLR-FRS具有最高的AUROC。
■对于UGIB患者,高NLR与高危UGIB密切相关.结合GBS和FRS测试可以取得良好的预测效果,这对于指导急诊护理和临床治疗的预检和分诊,确保患者得到快速有效的治疗,提高护理质量具有重要的指导意义。
UNASSIGNED: The neutrophil-lymphocyte ratio (NLR) is a simple marker of systemic inflammatory responses. The present study aims to evaluate the prognostic significance of the NLR on admission day in predicting outcomes for patients with upper gastrointestinal bleeding (UGIB), which is a prevalent medical emergency.
UNASSIGNED: 726 patients who were admitted to our clinic between January 2019 and December 2022 diagnosed with UGIB, and who underwent necessary examinations, were included in the study. The patients\' Glasgow-Blatchford Score (GBS), Full Rockall Score (FRS), and NLR levels were calculated at the first admission. Outcomes were defined as in-hospital mortality, need for blood transfusion, surgical treatment and endoscopic therapy. Patients were categorized into four groups using NLR quartile levels to compare their clinical characteristics, Glasgow Blatchford Score, Full Rockall Score levels, and prognosis. Secondary, we modified FRS and GBS by adding NLR, respectively. We used area under the receiver operating characteristic curve (AUROC) to assess the accuracy of risk prediction for NLR, NLR-GBS, and NLR-FRS improved models.
UNASSIGNED: Of 726 patients, 6% died in hospital, 23.9% received endoscopic interventon, 4.8% received surgical treatment, and 46.4% received transfusion therapy. Multifactorial logistic regression showed that a high level of NLR was a risk factor for death in patients with UGIB (p = 0.028). NLR, GBS, FRS, NLR-GBS, and NLR-FRS have sufficient accuracy in predicting inpatient mortality, endoscopic treatment, and transfusion treatment, and the differences are statistically significant (p < 0.05). In the comprehensive prediction of adverse outcomes, NLR-GBS has the highest AUROC, and in predicting inpatient mortality, NLR-FRS has the highest AUROC.
UNASSIGNED: For UGIB patients, a high NLR was strongly associated with high risk UGIB. Combined testing with the GBS and FRS can achieve good predictive results, which is valuable in guiding the pre-screening and triage of emergency nursing care and clinical treatment to ensure that patients receive rapid and effective treatment and improve the quality of care.