■描述COVID-19患者因胸膜并发症而接受管状胸腔造口术的患者的治疗结果,并确定患者状况与治疗结果之间的关系。
对菲律宾大学-菲律宾总医院(UP-PGH)于2020年3月30日至2021年3月31日接受了因COVID-19感染并发症而进行的导管胸造口术患者的单机构回顾性研究。这些患者的人口统计学和临床特征使用中位数进行评估,频率,和百分比。患者概况之间的关联,使用单变量Cox比例风险回归分析评估死亡率和再干预率.
■因COVID-19肺炎入院的3,397例患者中有34例(1.00%)接受了管状胸腔造口术。其中,34,47.06%为男性,52.94%为女性,中位年龄为51.5岁,85.29%有合并症,29.41%曾有或正在进行的结核性感染。胸管造口术最常见的适应症是胸腔积液(61.76%),其次是气胸(29.41%),和肺性胸腔积液(8.82%)。死亡率为38.24%,再干预率为14.71%。插管患者的死亡率是室内空气患者的14.84倍。降钙素原水平每增加一个单位,死亡风险增加了1.06倍.
■在因胸膜并发症而接受胸管造口术的COVID-19患者中,入院时氧气支持水平的增加和降钙素原水平与死亡风险直接相关。没有足够的证据表明与病人有关,COVID-19肺炎相关,纳入本研究的手术相关因素与再干预风险显著相关.
UNASSIGNED: To describe the treatment outcomes of patients who underwent tube thoracostomy for pleural complications in patients with COVID-19 and determine the association between patient profile and treatment outcomes.
UNASSIGNED: A single-institution retrospective review of patients who underwent tube thoracostomy for complications of COVID-19 infection in the University of the Philippines - Philippine General Hospital (UP-PGH) from March 30, 2020, to March 31, 2021, was performed. These patients\' demographic and clinical profiles were evaluated using median, frequencies, and percentages. The association between patient profile, and mortality and reintervention rates was assessed using univariable Cox proportional hazards regression analysis.
UNASSIGNED: Thirty-four (34) of 3,397 patients (1.00%) admitted for COVID-19 pneumonia underwent tube thoracostomy. Of these, 34, 47.06% were male, 52.94% were female, the median age was 51.5 years old, 85.29% had comorbid conditions, and 29.41% had a previous or ongoing tuberculous infection. The most common indication for tube thoracostomy was pleural effusion (61.76%), followed by pneumothorax (29.41%), and pneumo-hydrothorax (8.82%). The mortality rate was 38.24%, and the reintervention rate was 14.71%. Intubated patients had 14.84 times higher mortality hazards than those on room air. For every unit increase in procalcitonin levels, the mortality hazards were increased by 1.06 times.
UNASSIGNED: An increasing level of oxygen support on admission and a level of procalcitonin were directly related to mortality risk in COVID-19 patients who underwent tube thoracostomy for pleural complications. There is insufficient evidence to conclude that patient-related, COVID-19 pneumonia-related, and procedure-related factors included in this study were significantly associated with reintervention risk.