UNASSIGNED:我们先前的研究报道了一种用于急性肠梗阻患者的肠梗阻管的新型深层插管技术(DIT)。本研究旨在使用大型队列评估这种新技术对梗阻患者临床结局的影响。
UNASSIGNED:回顾性分析2014年至2019年在五家医院接受插管技术的496例梗阻患者的详细临床资料。将患者分为DIT组或传统插管技术(TIT)组。两组以1:1的比例使用倾向评分进行匹配,主要结局是患者的短期临床结局.
UNASSIGNED:匹配后DIT组和TIT组的基线特征相似。与TIT组相比,DIT组的插管深度明显更深,住院天数较短,第一次排气和排便的时间较短,较低的疼痛评分,增加排水量,和较低的紧急手术率。重要的是,炎症因子如白细胞,C反应蛋白,DIT组的降钙素原水平明显降低。此外,DIT治疗对粘连性梗阻患者显著有用.
未经证实:与TIT程序相比,DIT程序带来了更好的短期临床结果,说明DIT是一种安全可行的治疗肠梗阻的技术,值得进一步推广应用。
UNASSIGNED: Our previous research reported a novel deeper intubation technique (DIT) of the ileus tube for acute bowel obstruction patients. The present study was designed to evaluate the effect of this novel technique on the clinical outcomes of patients with obstruction using a large cohort.
UNASSIGNED: The detailed clinical data were analyzed retrospectively from 496 obstruction patients who underwent intubation technique from 2014 to 2019 in five hospitals. The patients were divided into either the DIT group or the traditional intubation technique (TIT) group. The groups were matched in a 1:1 ratio using propensity scores, and the primary outcome was the short-term clinical outcomes for patients.
UNASSIGNED: The baseline characteristics were similar between the DIT group and the TIT group after matching. Compared with the TIT group, the DIT group had a significantly deeper intubation depth, with shorter hospital days, shorter time to first flatus and defecation, lower pain score, increased drainage volume, and lower emergency surgery rate. Importantly, the inflammatory factors such as white blood cell, C-reactive protein, and procalcitonin levels were significantly lower in the DIT group. In addition, the DIT treatment was significantly useful for adhesive obstruction patients.
UNASSIGNED: The DIT procedure led to better short-term clinical outcomes compared with the TIT procedure, indicating that DIT is a safe and feasible technique for the treatment of intestinal obstruction that is worthy of further popularization and clinical application.