伤口被认为是表皮的深度割伤或撕裂,这也被称为创伤和对身体组织的伤害。伤口的愈合需要一系列协调的细胞过程,包括细胞吸引,扩散,分化,和血管生成。这些过程涉及各种细胞之间的相互作用,比如巨噬细胞,内皮细胞,角质形成细胞,成纤维细胞,生长激素,和蛋白酶。如果治疗不当,伤口的后果可能是致命的,导致慢性伤口,慢性疼痛,甚至死亡。伤口愈合是用组织修复和再生代替缺失的组织。一些局部变量是组织浸渍的存在,外来物体,生物膜,缺氧,缺血,和伤口感染。持续生长因子输送,siRNA递送,micro-RNA靶向,和干细胞疗法都是伤口愈合的新兴可能治疗方法。传统方法,比如阿育吠陀,西达,和Unani药物,也被用于治疗。纳米制剂在伤口感染中的治疗应用已经显示出各种有益效果。几种草药,特别是精油已经显示出潜在的伤口愈合活性,比如薰衣草,茶树,芝麻,橄榄,等。已经在伤口愈合疗法中探索了各种纳米颗粒及其纳米制剂。本综述文章强调了精油通过新型药物递送系统用于伤口愈合活性的几个方面。Further,一些通过草药治疗伤口的专利已经上市。
The wound has been recognised as a deep cut or tearing of the epidermis, which is also referred to as trauma and harm to the body tissues. Healing of wounds requires a coordinated series of cellular processes, including cell attraction, proliferation, differentiation, and angiogenesis. These processes involve interactions between various cells, such as macrophages, endothelial cells, keratinocytes, fibroblasts, growth hormones, and proteases. The outcome of wounds can be fatal if not treated properly, resulting in chronic wounds, chronic pain, and even death. Wound healing is replacing missing tissue with tissue repairs and regeneration. Some local variables are the presence of tissue maceration, foreign objects, biofilm, hypoxia, ischemia, and wound infection. Sustained growth factor delivery, siRNA delivery, micro-RNA targeting, and stem cell therapy are all emerging possible therapeutic approaches for wound healing. Traditional approaches, such as Ayurveda, Siddha, and Unani medicines, are also being used for treatment. The therapeutic application of nanoformulations in wound infections has shown various beneficial effects. Several herbal medicines, especially essential oils have shown potential wound healing activities, such as lavender, tea tree, sesame, olive, etc. Various nanoparticles and their nanoformulations have been explored in wound healing therapy. The present review article highlights several aspects of essential oils for wound healing activity through a novel drug delivery system. Further, some patents on wound healing through herbal medicine have been listed.