topical corticosteroid withdrawal

  • 文章类型: Journal Article
    目的:观察分次射频微针疗法(FRM)治疗糖皮质激素性面部红斑的疗效。
    方法:进行了一项回顾性研究,纳入了8例被诊断为皮质类固醇激素性面部红斑的患者。每位患者接受一次FRM治疗。评估措施包括临床医生红斑评估(CEA),患者自我评估(PSA),毛细血管扩张严重程度的评估,手术相关疼痛(10分量表),患者满意度(3分量表)和次要结果。
    结果:研究发现,在缓解红斑症状方面,成功率为75%,有效率为100%。CEA和PSA评分分别下降67.7%和78.1%,分别。在3个月的随访期间,没有记录到红斑反弹的病例。
    结论:FRM显示出治疗面部红斑的有效性和安全性,在皮肤病治疗方面提供有希望的进展。
    To investigate the efficacy of Fractional Radiofrequency Microneedling (FRM) in treating corticosteroid-induced facial erythema.
    A retrospective study was conducted involving eight patients diagnosed as corticosteroid-induced facial erythema. Each patient underwent a single session of FRM. Evaluative measures included Clinician\'s Erythema Assessment (CEA), Patient\'s Self-Assessment (PSA), assessment of telangiectasia severity, procedure-associated pain (10-point scale), patient satisfaction (3-point scale) and secondary outcomes.
    The study found a 75% success rate and 100% effectiveness rate in alleviating erythema symptoms. CEA and PSA scores decreased by 67.7% and 78.1%, respectively. No cases of erythema rebound were recorded during the 3-month follow-up period.
    FRM demonstrated effectiveness and safety in treating facial erythema, offering promising advancement in dermatologic therapeutics.
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  • 文章类型: Journal Article
    BACKGROUND: The National Eczema Association has received increasing numbers of patient inquiries regarding \"steroid addiction syndrome,\" coinciding with the growing presence of social media dedicated to this topic. Although many of the side effects of topical corticosteroids (TCS) are addressed in guidelines, TCS addiction is not.
    OBJECTIVE: We sought to assess the current evidence regarding addiction/withdrawal.
    METHODS: We performed a systematic review of the current literature.
    RESULTS: Our initial search yielded 294 results with 34 studies meeting inclusion criteria. TCS withdrawal was reported mostly on the face and genital area (99.3%) of women (81.0%) primarily in the setting of long-term inappropriate use of potent TCS. Burning and stinging were the most frequently reported symptoms (65.5%) with erythema being the most common sign (92.3%). TCS withdrawal syndrome can be divided into papulopustular and erythematoedematous subtypes, with the latter presenting with more burning and edema.
    CONCLUSIONS: Low quality of evidence, variability in the extent of data, and the lack of studies with rigorous steroid addiction methodology are limitations.
    CONCLUSIONS: TCS withdrawal is likely a distinct clinical adverse effect of TCS misuse. Patients and providers should be aware of its clinical presentation and risk factors.
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