背景:登革热(DF)源于登革热病毒(DENV),由节肢动物传播的一种常见的病毒性疾病。这种医疗状况有可能导致严重的并发症,包括但不限于肝功能衰竭,弥散性血管内凝血,登革热脑病,心肌炎,急性肾功能衰竭,和溶血性尿毒综合征.评估登革热的心脏表现对于及时干预和重症监护以挽救患者生命至关重要。
方法:一项纵向研究涉及104名新市民医院内科收治的登革热患者,苏拉特,2021年5月至2021年10月,以确定潜在的心脏受累。
结果:研究发现,在104名患者中,28例(26.92%)根据临床表现显示心脏受累。在这些患者中,28例(26.92%)心电图异常,39例(37.50%)显示肌酸激酶同工酶(CK-MB)水平升高。在28例心电图改变的患者中,14(50%)显示异常的2D超声心动图(ECHO)结果。最常见的心电图异常是V1-V4的T波倒置。主要的2D-ECHO发现是轻度心包积液。
结论:登革热的心脏受累不典型,可导致心肌炎等疾病,心律失常,心力衰竭,或震惊。评估登革热患者的心脏表现对于适当的管理至关重要。
BACKGROUND: Dengue fever (DF) arises from the dengue virus (DENV), a common viral illness transmitted by arthropods. This medical condition has the potential to result in severe complications, including but not limited to liver failure, disseminated intravascular coagulation, dengue encephalopathy, myocarditis, acute renal failure, and hemolytic uremic syndrome. Evaluating cardiac manifestations in dengue is crucial for timely intervention and intensive care to save patients\' lives.
METHODS: A longitudinal study involved 104 dengue fever patients admitted to the Department of Medicine at New Civil Hospital, Surat, between May 2021 and October 2021, to identify potential cardiac involvement.
RESULTS: The study found that out of the 104 patients, 28 (26.92%) showed cardiac involvement based on clinical manifestations. Among these patients, 28 (26.92%) exhibited abnormal ECG results, and 39 (37.50%) showed elevated creatine kinase-MB (CK-MB) levels. Of the 28 patients who showed ECG changes, 14 (50%) displayed abnormal 2D-echocardiography (ECHO) results. The most common electrocardiographic anomaly was a T-wave inversion in V1-V4. The predominant 2D-ECHO finding was mild pericardial effusion.
CONCLUSIONS: Cardiac involvement in dengue presents atypically and can lead to conditions like myocarditis, arrhythmias, cardiac failure, or shock. Assessing cardiac manifestations in dengue patients is pivotal for appropriate management.