three-level meta-analysis

  • 文章类型: Journal Article
    随着对基于游戏的精神障碍数字干预的研究越来越关注,已经进行了许多研究,以探索基于数字游戏的干预措施对精神障碍的有效性。然而,以前的研究结果不一致。这项研究对基于游戏的数字干预对精神障碍的有效性进行了全面的荟萃分析。通过在数据库中搜索文章,我们确定了53项研究,其中涉及2433名参与者,并提取了282个效应大小。在53项研究中,14采用组内(前/后)设计,其余39个采用对照试验设计。使用三级随机效应元分析模型,在对照试验设计中显示了基于游戏的数字干预的中等效果大小(g=0.47,95%CI:0.33,0.61),并且在组内(前/后)设计中发现了接近中等效果大小(g=0.45,95%CI:0.32,0.58)。表明基于游戏的数字干预对精神障碍的中等疗效。主持人分析显示,对照试验设计中的年龄导致了以前研究中的异质性,表明干预措施可能对老年人更有效,应该指出的是,只有有限数量的研究集中在这个年龄组。未来可以对老年参与者进行更多研究,以提供更有力的证据,并探索数字游戏干预如何更有效地改善精神障碍症状的机制。
    With increasing research attention on game-based digital interventions for mental disorders, a number of studies have been conducted to explore the effectiveness of digital game-based interventions on mental disorders. However, findings from previous research were inconsistent. Thus, we conducted a comprehensive meta-analytic review of the effectiveness of game-based digital interventions for mental disorders. By searching the articles in databases, we identified 53 studies in which 2433 participants were involved, and 282 effect sizes were extracted. Among the 53 studies, 14 employed within-group (pre/post) designs, and the remaining 39 utilized controlled trial designs. Using a three-level random-effects meta-analytic model, a medium effect size of game-based digital interventions (g = 0.47, 95 % CI: 0.33, 0.61) was revealed in the controlled trial designs and a close-to-medium effect size (g = 0.45, 95 % CI: 0.32, 0.58) was found in the within-group (pre/post) designs, indicating close-to-medium-sized efficacy of game-based digital interventions for mental disorders. Moderator analyses showed that age in the controlled trial designs had contributed to the heterogeneity in previous studies, suggesting that interventions might be more effective for the elderly. However, given that only a limited number of studies were focused on the elderly, more studies with older participants should be conducted in the future to provide more robust evidence and explore the mechanisms of how digital gaming interventions can be more effective in improving mental disorders symptoms.
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  • 文章类型: Journal Article
    特质正念已显示出缓解与睡眠问题有关的症状的潜力,但是在不同的研究中,特质正念和睡眠问题之间的关系各不相同。为了探索这种关联并获得可靠的估计,按照系统评价和荟萃分析(PRISMA)方法的首选报告项目进行三级荟萃分析。一项全面的文献检索确定了86项研究,涉及87个独立样本和35,521名参与者。总共分析了441种效应大小。该研究表明,特质正念与睡眠问题之间存在负相关。此外,荟萃分析揭示了研究设计的显著调节作用,正念方面,以及对这种关系的特质正念的测量。这项研究表明,特质正念与睡眠问题的缓解密切相关。此外,特质正念对于加强针对个人睡眠问题的预防和干预措施至关重要。
    Trait mindfulness has shown potential in relieving the symptoms related to sleep problems, but the relationship between trait mindfulness and sleep problems varies across studies. To explore this association and obtain reliable estimates, a three-level meta-analysis was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) approach. A comprehensive literature search identified 86 studies involving 87 independent samples and 35,521 participants. A total of 441 effect sizes were analyzed. The study indicated a negative association between trait mindfulness and sleep problems. Furthermore, the meta-analysis revealed significant moderating effects of study design, mindfulness facets, and measurement for trait mindfulness on this relationship. This study suggests that trait mindfulness is closely related to the alleviation of sleep problems. Furthermore, trait mindfulness is vital important in strengthening prevention and intervention measures targeting individuals\' sleep problems.
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  • 文章类型: Journal Article
    背景:执行功能(EF)和情景记忆是认知的基本组成部分,随着年龄的增长而恶化,对于独立生活至关重要。尽管许多评论都探讨了运动对老年人这些组成部分的影响,这些评论筛选和分析了选定的老年人群,或特定的锻炼模式,因此,对于运动对老年认知的影响这一基本问题,只提供了有限的答案。本文介绍了旨在评估不同类型的慢性运动在改善和/或维持老年人EF和长期情景记忆方面的有效性的系统综述和多层次荟萃分析研究的方案。
    方法:研究方案按照系统评价和荟萃分析(PRISMA)指南的首选报告项目编写。将搜索多个数据库。在年龄≥60岁的老年人中进行的随机对照试验(RCT),提供任何类型的计划,结构化,和重复的运动干预,和EF和/或情景记忆测量作为结果,将包括在同行评审期刊上以英文发表的论文和博士论文。两名独立审阅者将筛选选定的文章,而第三位审稿人将解决可能的冲突。Cochrane偏差风险工具将用于评估研究质量。最后,将从选定的文章中提取数据,并且将使用随机效应多水平荟萃分析来应用从所选研究中合并个体数据的正式方法。数据分析将使用R.
    结论中的metafor软件包进行:本综述将综合现有证据,并指出文献中关于运动对EF和情景记忆的影响的差距健康和不健康的老年人。这项荟萃分析的结果将有助于为老年人设计有效的运动干预措施,以改善和/或维持EF和情景记忆。其结果将对许多研究人员和与老年人及其家人一起工作的专业人员有用。
    背景:PROSPEROCRD42022367111.
    BACKGROUND: Executive functions (EFs) and episodic memory are fundamental components of cognition that deteriorate with age and are crucial for independent living. While numerous reviews have explored the effect of exercise on these components in old age, these reviews screened and analyzed selected older adult populations, or specific exercise modes, thus providing only limited answers to the fundamental question on the effect of exercise on cognition in old age. This article describes the protocol for a systematic review and multilevel meta-analytic study aiming at evaluating the effectiveness of different types of chronic exercise in improving and/or maintaining EFs and long-term episodic memory in older adults.
    METHODS: The study protocol was written in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Several databases will be searched. Randomized controlled trials (RCTs) conducted in older adults aged ≥ 60 years providing any kind of planned, structured, and repetitive exercise interventions, and EFs and/or episodic memory measures as outcomes, published in English in peer-reviewed journals and doctoral dissertations will be included. Two independent reviewers will screen the selected articles, while a third reviewer will resolve possible conflicts. The Cochrane risk-of-bias tool will be used to assess the quality of the studies. Finally, data will be extracted from the selected articles, and the formal method of combining individual data from the selected studies will be applied using a random effect multilevel meta-analysis. The data analysis will be conducted with the metafor package in R.
    CONCLUSIONS: This review will synthesize the existing evidence and pinpoint gaps existing in the literature on the effects of exercise on EFs and episodic memory in healthy and unhealthy older adults. Findings from this meta-analysis will help to design effective exercise interventions for older adults to improve and/or maintain EFs and episodic memory. Its results will be useful for many researchers and professionals working with older adults and their families.
    BACKGROUND: PROSPERO CRD42022367111.
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  • 文章类型: Systematic Review
    目的:帕金森病(PD)是一种影响全球数百万人的神经退行性疾病。舞蹈已成为增强该人群福祉的综合干预措施。这项荟萃分析旨在评估舞蹈对PD患者心理健康和生活质量的影响。
    方法:2022年12月检索了三个数据库。包括研究论文,比较了舞蹈与非舞蹈控制对PD患者生活质量或心理健康的影响。两位作者独立筛选了这些研究,提取的数据,并评估合格研究的方法学质量。为了解决研究中效应大小的相互依存关系,采用三级荟萃分析方法对数据进行分析.
    结果:共纳入了13项试验,共496名受试者,其中11人接受统计分析。结果表明,与被动对照组相比,舞蹈对心理健康(g=0.43,95%CI=[0.11,0.75])和生活质量(g=0.46,95%CI=[-0.04,0.95])有积极影响。主持人分析显示,非合作舞蹈和总剂量较低的舞蹈干预对心理健康特别有益。
    结论:舞蹈干预是提高PD患者心理健康和生活质量的有效生活方式活动。提出了一个理论框架来解释舞蹈对神经学幸福感的影响,社会,物理,和心理学观点。
    OBJECTIVE: Parkinson\'s disease (PD) is a neurodegenerative disease that affects millions of individuals worldwide. Dance has emerged as a comprehensive intervention for enhancing well-being in this population. This meta-analysis aimed to assess the effectiveness of dance on mental health and quality of life among individuals with PD.
    METHODS: Three databases were searched in December 2022. Research papers comparing the effects of dance with a non-dance control on the quality of life or mental health of individuals with PD were included. Two authors independently screened the studies, extracted data, and assessed methodological quality of eligible studies. To address the interdependence of effect sizes within studies, the three-level meta-analysis approach was employed to analyze the data.
    RESULTS: Thirteen trials involving a total of 496 participants were included, with 11 being subjected to statistical analysis. The results indicated that dance had a positive impact on mental health (g = 0.43, 95 % CI = [0.11, 0.75]) and quality of life (g = 0.46, 95 % CI = [-0.04, 0.95]) when compared to passive control groups. Moderator analyses revealed that non-partnered dance and dance interventions with lower total dosages were particularly beneficial for mental health.
    CONCLUSIONS: Dance interventions are an effective lifestyle activity for enhancing mental health and quality of life in individuals with PD. A theoretical framework is proposed to explain the impact of dance on well-being from neurological, social, physical, and psychological perspectives.
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  • 文章类型: Meta-Analysis
    许多研究探索了年轻人对情绪的识别程度与其内在化问题之间的联系,但是共识仍然难以捉摸。本研究采用三级荟萃分析模型,定量综合现有研究的结果来评估这种关系。还进行了适度分析,以探索研究异质性的来源。通过系统的文献检索,目前的荟萃分析共检索了42项具有201个效应大小的研究,包括7579名参与者。情绪识别与内在化问题呈负相关。情绪识别能力较弱的儿童和青少年更有可能出现内在化问题。此外,这项荟萃分析发现,发表年具有显著的调节作用.情绪识别和内在化问题之间的相关性随着时间的推移而下降。内部化问题的程度也被发现是一个重要的调节因素。情绪识别与内化障碍的相关性高于情绪识别与内化症状的相关性。情绪识别的缺陷可能与儿童和青少年内在化问题的发展和/或维持有关。总体效果较小,未来的研究应探索该关联的临床相关性。
    Numerous studies have explored the link between how well youth recognize emotions and their internalizing problems, but a consensus remains elusive. This study used a three-level meta-analysis model to quantitatively synthesize the findings of existing studies to assess the relationship. A moderation analysis was also conducted to explore the sources of research heterogeneity. Through a systematic literature search, a total of 42 studies with 201 effect sizes were retrieved for the current meta-analysis, and 7579 participants were included. Emotion recognition was negatively correlated with internalizing problems. Children and adolescents with weaker emotion recognition skills were more likely to have internalizing problems. In addition, this meta-analysis found that publication year had a significant moderating effect. The correlation between emotion recognition and internalizing problems decreased over time. The degree of internalizing problems was also found to be a significant moderator. The correlation between emotion recognition and internalizing disorders was higher than the correlation between emotion recognition and internalizing symptoms. Deficits in emotion recognition might be relevant for the development and/or maintenance of internalizing problems in children and adolescents. The overall effect was small and future research should explore the clinical relevance of the association.
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  • 文章类型: Journal Article
    虐待儿童是导致网络成瘾的重要因素。尽管有许多研究观察到虐待儿童和网络成瘾之间存在正相关,这种关联的强度在以前的研究中存在很大差异.这项研究旨在获得对效果大小的可靠估计,并调查虐待儿童与网络成瘾之间关联的潜在调节因素。31项研究通过系统的文献检索报告了虐待儿童与网络成瘾之间的关联(273个效应大小和55,585名参与者)。基于系统评价和荟萃分析方法的首选报告项目,采用三级模型进行三级荟萃分析.当前的荟萃分析发现,虐待儿童与网络成瘾呈显着正相关。此外,研究发现,虐待儿童的类型和发表年份对虐待儿童和网络成瘾之间的关系有显著的调节作用。这项研究表明,虐待儿童是网络成瘾的危险因素。此外,在加强对个人网络成瘾的干预措施时,应该考虑虐待儿童的一个重要因素。
    Child abuse is an important factor for Internet addiction. Despite numerous researches had observed there was a positive correlation between child abuse and Internet addiction, the strength of this association differed considerably in the previous studies. This study aims to obtain reliable estimates for effect sizes and investigate the potential moderator of the association between child abuse and Internet addiction. Thirty-one studies reported the association between child abuse and Internet addiction (273 effect sizes and 55,585 participants) through a systematic literature search. Based on Preferred Reporting Items for Systematic Review and Meta-Analysis approach, a three-level model was employed to conduct a three-level meta-analysis. The current meta-analysis found that child abuse was significantly positively correlated with Internet addiction. Besides, the study found that the type of child abuse and publication year had significant moderating effects on the association between child abuse and Internet addiction. This study suggested child abuse was a risk factor for Internet addiction. Moreover, child abuse is an essential factor should be considered when strengthening interventions for individuals\' Internet addiction.
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  • 文章类型: Systematic Review
    尽管工作记忆(WM)是数学问题解决(MPS)的重要因素,目前尚不清楚WM与MPS的关系。因此,我们旨在通过荟萃分析来确定这种关系.我们在电子数据库中搜索了2000年至2020年之间发表的研究,并建立了操作标准。我们进行了Egger的回归测试,并创建了漏斗图来测试发表偏倚。最后,对来自130项研究的数据进行的三水平荟萃分析模型分析,这些研究涉及43,938名参与者和1,355个效应大小,结果显示WM和MPS之间存在中等关系(r=0.280,95%CI=[0.263,0.314]).此外,主持人分析表明:(1)装扮词问题与WM的联系比与数学内部问题的联系更紧密;(2)中央执行功能与MPS的关系最强,而语音回路最弱;(3)性别比例具有显着的调节作用;(4)上述显着的调节作用在控制其他因素后是独特的。还讨论了对研究和实践的影响。
    Although working memory (WM) is an important factor in mathematical problem solving (MPS), it remains unclear how well WM relates to MPS. Thus, we aimed to determine this relationship by using a meta-analysis. We searched electronic databases for studies published between 2000 and 2020 and established operational criteria. We conducted Egger\'s regression tests and created funnel plots to test for publication bias. Finally, a three-level meta-analytic model analysis of data from 130 studies involving 43,938 participants and 1,355 effect sizes revealed a moderate relationship between WM and MPS (r = 0.280, 95% CI = [0.263, 0.314]). Moreover, moderator analyses showed that: (1) dressed-up word problems were more strongly tied to WM than to intra-mathematical problems; (2) the central executive function showed the strongest relation with MPS, whereas the phonological loop had the weakest; (3) gender ratio had significant moderating effects; and (4) some of the above-mentioned significant moderating effects were unique after controlling for other factors. Implications for research and practice were also discussed.
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  • 文章类型: Journal Article
    基于正念的干预(MBI)对患有精神疾病和身体疾病的患者的炎症和压力的生物标志物具有积极影响。关于亚临床人群,结果不太清楚。本荟萃分析探讨了MBIs对精神病人群和健康人群中生物标志物的影响。强调,和高危人群。所有可用的生物标志物数据都用全面的方法进行了调查,使用两个三级荟萃分析。治疗组内生物标志物水平的前后变化(k=40项研究,总N=1441)和治疗效果与对照组效果相比,仅使用RCT数据(k=32,总N=2880),大小相似,对冲g=-0.15(95%CI=[-0.23,-0.06],p<0.001)和g=-0.11(95%CI=[-0.23,0.001],p=0.053)。当包括可用的随访数据时,影响的幅度增加,但样本类型之间没有差异,MBI,生物标志物,和对照组或MBI的持续时间。这表明MBI可以在小程度上改善精神病和亚临床人群中的生物标志物水平。然而,低研究质量和发表偏倚的证据可能对结果产生影响.在这个研究领域仍然需要更多的大型和预先注册的研究。
    Mindfulness-based interventions (MBIs) have a positive effect on biomarkers of inflammation and stress in patients with psychiatric disorders and physical illnesses. Regarding subclinical populations, results are less clear. The present meta-analysis addressed the effects of MBIs on biomarkers in psychiatric populations and among healthy, stressed, and at-risk populations. All available biomarker data were investigated with a comprehensive approach, using two three-level meta-analyses. Pre-post changes in biomarker levels within treatment groups (k = 40 studies, total N = 1441) and treatment effects compared to control group effects, using only RCT data (k = 32, total N = 2880), were of similar magnitude, Hedges g = -0.15 (95% CI = [-0.23, -0.06], p < 0.001) and g = -0.11 (95% CI = [-0.23, 0.001], p = 0.053). Effects increased in magnitude when including available follow-up data but did not differ between type of sample, MBI, biomarker, and control group or duration of the MBI. This suggests that MBIs may ameliorate biomarker levels in both psychiatric and subclinical populations to a small extent. However, low study quality and evidence of publication bias may have impacted on the results. More large and preregistered studies are still needed in this field of research.
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  • 文章类型: Meta-Analysis
    认知重估和表达抑制一直被认为是两种最重要的情绪调节策略。越来越多,研究发现正念与他们有关系。然而,它们之间关系的大小和方向尚未得出一致的结论。为此,使用三级荟萃分析来探索正念之间的关系,认知重估,和表现力抑制。通过文献检索将36项研究纳入荟萃分析,包括36个样本,83个效应大小,总共12,026名受试者。三级随机效应模型表明,正念与认知重估呈正相关,而与表达抑制无关。调节效应分析表明,男性的正念与认知重评之间的关系比女性的关系更为密切。研究发现,正念和认知重估之间存在相对稳定的正相关关系,一种适应性情绪调节模式,而与表达抑制的关系微不足道。这一发现支持了影响调节训练模型,也揭示了未来研究的潜在领域。
    Cognitive reappraisal and expressive suppression have long been considered the two most important emotion regulation strategies. Increasingly, studies have found that mindfulness has a relationship with them. However, the magnitude and direction of the relationship between them have yet to reach a consistent conclusion. To this end, a three-level meta-analysis was used to explore the relationship between mindfulness, cognitive reappraisal, and expressive suppression. Thirty-six studies were included in the meta-analysis through a literature search, including 36 samples with 83 effect sizes and a total of 12,026 subjects. The three-level random effects model showed that mindfulness was positively correlated with cognitive reappraisal to a low to moderate degree but was not correlated with expressive suppression. The moderating effect analysis showed that the relationship between mindfulness and cognitive reappraisal was slightly closer in males than in females. The study found a relatively stable positive relationship between mindfulness and cognitive reappraisal, an adaptive emotion regulation mode, while the relationship with expressive suppression was insignificant. The finding supported the affect regulation training model and also shed light on potential areas for future studies.
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  • 文章类型: Systematic Review
    新出现的证据表明,儿童虐待与病理性自恋的两种表型之间存在正相关关系(即,脆弱和宏伟的自恋)。然而,这些研究的结果不一致。因此,本荟萃分析旨在检查虐待儿童与脆弱和傲慢的自恋相关的程度,以及这些关联是否因研究或样本特征而异。在WebofScience上进行了系统的文献综述,ScienceDirect,PubMed,谷歌学者,和中国国家知识基础设施。在R中进行三级荟萃分析以合成效应大小。总共包括15项研究(N=9,141名参与者),产生129个效应大小。结果表明,儿童虐待与脆弱的自恋(平均r=.198;p<.001)和夸张的自恋(平均r=.087;p<.001)呈正相关,但只是在很小的程度上。Further,儿童虐待和脆弱自恋之间的关联在忽视(r=0.278)比身体虐待(r=0.130)更强。平均年龄小于18岁的样本(r=.187)比平均年龄大于18岁的样本(r=.068),儿童虐待与自恋之间的关联强度更大。此外,女性的关联强度比男性强。虐待儿童是发展脆弱和傲慢自恋的危险因素。针对病理性自恋的干预措施应意识到因虐待儿童而造成的潜在创伤。
    Emerging evidence has documented the positive association between child maltreatment and both phenotypes of pathological narcissism (i.e., vulnerable and grandiose narcissism). However, results across these studies are inconsistent. Therefore, the present meta-analysis aimed to examine the extent to which child maltreatment is associated with vulnerable and grandiose narcissism, and whether these associations differed by study or sample characteristics. A systematic literature review was conducted in Web of Science, ScienceDirect, PubMed, Google Scholar, and China National Knowledge Infrastructure. Three-level meta-analyses were performed in R to synthesize the effect sizes. A total of 15 studies (N = 9,141 participants) producing 129 effect sizes were included. Results showed that child maltreatment was positively related to both vulnerable narcissism (mean r = .198; p < .001) and grandiose narcissism (mean r = .087; p < .001), but only to a small extent. Further, the association between child maltreatment and vulnerable narcissism was stronger for neglect (r = .278) than for physical abuse (r = .130). The strength of the association between child maltreatment and grandiose narcissism was larger for samples that were on average younger than 18 years (r = .187) than for samples that were on average older than 18 years (r = .068). Also, the strength of the association was stronger for females than for males. Child maltreatment is a risk factor for developing both vulnerable and grandiose narcissism. Interventions targeting pathological narcissism should be aware of potential trauma resulting from victimization of child maltreatment.
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