■体外生物力学研究,研究了整个规范性人胸椎(TS)和腰椎(LS)与肋骨的耦合运动。
■要量化TS的特定区域耦合运动模式和幅度,胸腰椎交界处(TLJ),同时LS。
■研究脊柱耦合运动对于理解复杂脊柱畸形的发展以及为验证计算模型提供数据非常重要。然而,体外报道的耦合运动模式是有争议的,并且没有关于整个人类TS和LS的区域特定耦合运动的定量数据。
■纯,将8Nm的无约束弯矩应用于七个新鲜冷冻的人类尸体TS和LS标本(平均年龄:70.3±11.3岁),并带有肋骨笼,以引起屈伸(FE),横向弯曲(LB),和轴向旋转(AR)。在每个主要运动期间,捕获特定区域的旋转运动范围(ROM)数据。
■无统计学意义,在主要FE期间观察到一致的耦合运动模式。在主LB期间,在TS中存在显著的同侧AR(p<0.05),在TLJ和LS中存在对侧耦合AR的一般模式。TS也有扩展和LS弯曲的趋势。在主要AR期间,TS中的同侧和TLJ和LS中的对侧是显着耦合的LB。在LS中也观察到显著的耦合屈曲。耦合的LB和ARROM在TS和LS之间或彼此之间没有显着差异。
■研究结果支持在LB和AR期间TS和LS一致的耦合运动模式的证据。这些新数据可作为计算模型验证和未来研究脊柱畸形和植入物的体外研究的参考。
UNASSIGNED: In vitro biomechanical study investigating the coupled motions of the whole normative human thoracic spine (TS) and lumbar spine (LS) with rib cage.
UNASSIGNED: To quantify the region-specific coupled motion patterns and magnitudes of the TS, thoracolumbar junction (TLJ), and LS simultaneously.
UNASSIGNED: Studying spinal coupled motions is important in understanding the development of complex spinal deformities and providing data for validating computational models. However, coupled motion patterns reported in vitro are controversial, and no quantitative data on region-specific coupled motions of the whole human TS and LS are available.
UNASSIGNED: Pure, unconstrained bending moments of 8 Nm were applied to seven fresh-frozen human cadaveric TS and LS specimens (mean age: 70.3 ± 11.3 years) with rib cages to elicit flexion-extension (FE), lateral bending (LB), and axial rotation (AR). During each primary motion, region-specific rotational range of motion (ROM) data were captured.
UNASSIGNED: No statistically significant, consistent coupled motion patterns were observed during primary FE. During primary LB, there was significant (p < 0.05) ipsilateral AR in the TS and a general pattern of contralateral coupled AR in the TLJ and LS. There was also a tendency for the TS to extend and the LS to flex. During primary AR, significant coupled LB was ipsilateral in the TS and contralateral in both the TLJ and LS. Significant coupled flexion in the LS was also observed. Coupled LB and AR ROMs were not significantly different between the TS and LS or from one another.
UNASSIGNED: The findings support evidence of consistent coupled motion patterns of the TS and LS during LB and AR. These novel data may serve as reference for computational model validations and future in vitro studies investigating spinal deformities and implants.