OBJECTIVE: Determine prevalence, risk factors and outcomes of hypertensive disorders in pregnancy (HDP).
METHODS: Cross-sectional analysis of data captured in the Maternal and Perinatal Database for Quality, Equity and Dignity (MPD-4-QED) between September 2019 and August 2020.
METHODS: Fifty-four referral level facilities in Nigeria.
METHODS: Women whose pregnancy ended (irrespective of the location or duration of pregnancy) or who were admitted within 42 days of delivery.
METHODS: Descriptive statistics and multilevel mixed-effects logistic regression models.
METHODS: Prevalence of HDP, sociodemographic and clinical factors associated with HDP and perinatal outcomes.
RESULTS: Among the 71 758 women 6.4% had HDP and gestational hypertension accounted for 49.8%. Preeclampsia and eclampsia were observed in 9.5% and 7.0% of all pregnancies, respectively. The predictors of HDP were age over 35 years (OR1.96, 95% CI 1.82-2.12; p < 0.001), lack of formal educational (OR 1.18, 95% CI 1.06-1.32; p = 0.002), primary level of education (OR 1.20, 95% CI 1.03-1.4; p < 0.002), nulliparity (OR 1.21, 95% CI 1.12-1.31; p < 0.001), grand-multiparity (OR 1.36, 95%CI 1.21-1.52; p < 0.001), previous caesarean section (OR 1.26, 95%CI 1.15-1.38; p < 0.001) and previous miscarriage (OR 1.22, 95% CI 1.13-1.31; p < 0.001). Overall 3.7% of the patients with HDP died, with eclampsia having the highest case fatality rate of 27.9%. Stillbirth occurred in 11.9% of pregnancies with hypertensive disorders.
CONCLUSIONS: Hypertensive disorders in pregnancy are not uncommon in Nigeria. They are associated with adverse outcomes with over one-quarter of women with eclampsia dying. The main predictors include older age, poor education, extremes of parity and previous CS or miscarriage. Maternal and perinatal outcomes are poor with about a quarter developing complications and about 1 in 10 having stillbirths.

The aim of the study was to examine the knowledge, attitude and uptake of the Human Papilloma Virus (HPV) vaccine among 302 parents whose adolescents\' children utilized care services at the General Practice Units (GPU) of the University of Benin Teaching Hospital (UBTH). Systematic sampling technique was used to select respondents for the study. Self-administered questionnaire that was pretested was used in collecting information from the respondents. The characteristics of the respondents were described using simple proportion and frequency. Also, knowledge and attitude of respondents on HPV and its vaccine were presented using simple proportion and frequency. The Chi-square test examined factors associated with uptake of HPV vaccine. The results indicate that 42.4% of the respondents have heard of HPV infection, whil only 18.5% have heard of HPV vaccine. By contrast, 18.5% of the respondents reported that their children had been vaccinated. Attitude of the respondents on the vaccine was not impressive given that only 34.4% reported that the vaccine was important, while 56.6% reported that they will advise their friends to be vaccinated. A higher proportion of children who were vaccinated were those whose parents believed that their children will be vulnerable without vaccination and those whose religion did not disapprove of the vaccination. We conclude that the knowledge of HPV among parents in this population is low; the knowledge of the vaccine and its uptake is low; while attitude towards the vaccine is unimpressive. We recommend the adoption of intervention programmes to improve the knowledge and encourage th uptake of the vaccine among adolescents in this population.

This study evaluated the essential stroke care structure available in the two Tertiary Health Facilities in Rives State, Nigeria. This was a descriptive survey involving the Stroke Care Survey and Assessment Tool (checklist/questionnaire) developed by the World Stroke Organisation to obtain information about the available essential stroke care structure (facilities, equipment, personnel and management protocol) at the two tertiary health facilities (RSUTH & UPTH). The study gathered relevant information, which was summarised into tables and graphs using Microsoft Excel 2016. From the results, although facilities had A and E departments, dedicated stroke units (fixed or mobile) were unavailable, and there was no locally developed protocol to support rapid triage of stroke patients. The facilities and equipment were either unavailable or insufficient. Only one health facility (RSUTH) provided 24 hrs/7 days laboratory services. The workforces were a mix between regular clinical staff and some specialists. Tissue plasminogen activator (tPA) use was non-existent, though specialists were trained on its administration. There was no locally developed or adopted stroke-specific clinical guidelines. In conclusion, the structural services available for stroke care within the studied tertiary health facilities were poor, unavailable or grossly insufficient. The state facility (RSUTH) suffered the most in terms of unavailable national support and staff development.