In total, 109 fish species (24,996 individuals) were sampled around Guadeloupe and Martinique Islands from October 2021 to September 2022 to estimate the morphometric relationships between total length and weight (Length Weight Relationship: LWR) of each fish species according to potential spatial, temporal and sex differences. Of these species, this is the first time that the LWR was estimated in the Atlantic Ocean for 16 species. There is a significant relationship between length and weight for all tested species. For 83 tested species, the sex effect on the LWR showed significant sexual dimorphism for 24 species. Additionally, a link between the temporal effect and the reproduction period was tested for 68 species, of which 35 presented significant differences relative to the annual quarter of sampling. Finally, the geographical effect (i.e., the difference between samples from around Guadeloupe Island and those from Martinique Island) was significant for 60 species. This island effect was significant for 25 species.

Uncertainty has been demonstrated to influence the perception of noxious stimuli, but little is known about the effects of prolonged uncertain contexts on the perception of painful and non-painful stimuli. To address this knowledge gap, the present study utilized a cue-based NPU-threat task, where uncertain and certain trials were separated into distinct blocks. The objective was to investigate the impact of uncertain contexts on the temporal dynamics of electroencephalogram (EEG) activity during the processing of painful and non-painful stimuli. The results revealed that the influence of uncertain contexts on neural responses extends beyond painful trials and is also evident in non-painful trials. In uncertain contexts, it has been observed that painful stimuli elicit larger P2 amplitudes and late beta band (13-30 Hz) event-related desynchronization (ERD) around 500-700 ms. However, in certain contexts, painful stimuli evoke stronger late gamma band (50-70 Hz) event-related synchronization (ERS) around 600-700 ms. For non-painful trials, in uncertain contexts, significantly higher amplitudes of the late positive potential (LPP) component and delta-theta band (2-7 Hz) ERS were observed compared to certain non-painful stimuli. These findings demonstrate that uncertain contexts exert a significant impact on the processing of both painful and non-painful stimuli, and this influence is mediated by distinct neural mechanisms.

The shifts in individual-level and neighborhood-level patterns of drug poisoning deaths in a high-density Asian city over time have been underestimated, although they provide essential information for community-based surveillance and interventions.
A case-only analysis with a 16-y, territory-wide, population-based registry in Hong Kong was applied to compare drug poisoning deaths from 2001 to 2010 with 2011 to 2016. Drug poisoning deaths, deaths from heroin and deaths from other opioids (codeine or morphine) were extracted (ICD codes: T36-T50, T40.1, T40.2). Binomial regressions were used to estimate the shifts in mortality patterns.
Among 3069 drug poisoning deaths, a significant shift in mortality patterns was found despite a decreasing mortality trend in Hong Kong. Overall, drug poisoning deaths shifted towards middle-aged/young-old, widowed/divorced, economically active, white collar and non-local born. Since 2011, more deaths from heroin were in older ages and non-local born, but less were never married and economically inactive. More deaths from other opioids were middle-aged, young-old and divorced. In particular, most decedents shifted towards young-old, especially deaths from other opioids. Compared with deaths during 2001-2010, there were 3.72- and 6.50-fold more deaths from heroin and deaths from other opioids in those aged ≥60 y since 2021 (ORs: 3.72 [2.37, 5.86], 6.50 [3.97, 10.65]), respectively. Additionally, drug poisoning deaths shifted towards areas with less neighborhood deprivation (more high-education individuals and a mix of private/public housing residents), especially deaths from other opioids.
Misuse of registered drugs (e.g. opioid pain relievers) could be a rising trend among vulnerable subpopulations in Hong Kong other than illegal drug use (heroin). Health officials should provide more advice and support on drug information. Specifically, an improved health system with education regarding the appropriate use of registered drugs for medical treatments should be provided to mid-/high-income and local-born individuals.

UNASSIGNED: It is easier for a listener to detect a brief tonal signal presented in a longer masking noise by increasing the delay between the signal and the masker. This phenomenon (overshoot) is influenced by a reduction in cochlear amplification and to date, there is no objective tool to investigate it. Therefore, a different paradigm of the auditory brainstem response (ABR) was utilized to measure auditory overshoot. It was assumed that increasing the delay onset time (DOT) between a signal and a masker reduces the latencies of waves I and III.
UNASSIGNED: Sixteen normal young male guinea pigs were tested. A tone burst stimulus (signal: 16 kHz, 5ms in duration) and wide-band noise (masker: 0.1-8.0 kHz, 100ms in duration) at three DOTs were used. To diminish the effect of the noise on waves, waveforms were subtracted from those derived from the noise burst alone. The absolute latency of the waves I and III, inter-peak latency of the waves I-III, and amplitude ratio of the waves III/I were compared for the 0, 30, and 100ms DOTs and five signal-to-noise ratios.
UNASSIGNED: The latencies of increased from the 0 to 30ms DOT and then decreased from the 30 to 100ms DOT (p < 0.001). No significant changes were observed in the latency waves at the 100ms DOT compared to the 0ms DOT (p > 0.005). Moreover, there were no significant differences between the three DOTs regarding the inter-peak latency and amplitude ratio of the waves (p <0.005).
UNASSIGNED: The study results showed an overshoot-like electrophysiological effect using ABR. Therefore, an objective test was used to investigate auditory cochlear gain.

Understanding the temporal effects of thinning on the composition and growth of regene-rated broadleaved woody species in coniferous plantations can provide profound references for promoting the conversion of monoculture plantations into mixed conifer-broadleaved forests, which could solve the problem that the production and ecological functions of monoculture plantations cannot be balanced. We compared the composition of regenerated woody plant species in Larix kaempferi plantation with short-term (1-3 years), medium-term (4-9 years) and long-term (>9 years) after thinning. Furthermore, we selected three regenerated tree species with higher importance value and reciprocal symbiosis with L. kaempferi, which differed in shade tolerance, including shade-intolerant species Quercus mongolica, intermediate shade-tolerant species Acer mono, and shade-tolerant species Tilia mandschurica. We analyzed the relationships between light conditions (i.e., canopy density) and the growth (i.e., base diameter and height) of those species in L. kaempferi plantation with different terms after thinning. The results showed that 46 species of regene-rated broadleaved woody plants were recorded in thinned plantations. The common and dominant tree in different terms after thinning was A. mono, and the shrub species were Lonicera japonica and Euonymus alatus. With the increasing time after thinning, species richness of regenerated trees decreased, but the ratio of tree to shrub species increased and the intermediate shade-tolerant tree species took the dominant position. The temporal effect of thinning on the growth of three tree species was affected by shade tolerance ability. Basal diameter and height of T. mandschurica were higher than those of Q. mongolica and A. mono. With the increases of time after thinning, basal diameter of T. mandschurica and height of A. mono were more sensitive to light, indicating that there were respectively \"a shade tolerance strategy\" and \"a shade avoidance strategy\" to adapt to the post-thinning environment. The effects of thinning on the composition and growth of regenerated broadleaved woody species in L. kaempferi plantations were significantly time-sensitive. When deve-loping thinning measures to promote the regeneration of broadleaved trees in plantations, we should consider to extend the thinning interval appropriately to ensure the growth of broadleaved tree seedlings (e.g., T. mandschurica and A. mono) and accelerate their migration into the canopy layer. This would promote the formation of mixed conifer-broadleaved forests and eventually realize the sustainable development of plantations.
明确间伐对针叶人工林林下更新阔叶木本植物组成和生长影响的时间效应,可为促进人工纯林向针阔混交林转化、进而解决纯林生产与生态功能无法兼顾的问题提供参考。本研究以我国北方重要针叶人工林——日本落叶松人工林为例,比较间伐后短期(1～3年)、中期(4～9年)和长期(>9年)人工林林下更新木本植物组成的差异;并选择具有较高重要值且与落叶松互惠共生的3种更新树种蒙古栎、色木槭、糠椴,分析不同间伐时期人工林内光照(郁闭度)与更新木本植物生长的关系。结果表明: 在间伐样地内更新的阔叶木本植物达46种,不同间伐时期样地内共有且占据优势的乔木树种为色木槭,灌木树种为忍冬和卫矛。随间伐后时间的推移,更新物种数逐渐减少,但乔灌比呈增大的趋势;中性树种占据优势地位。间伐对更新树种生长影响的时间效应受树种耐荫性的影响,糠椴的基径和树高均高于蒙古栎和色木槭。随间伐后时间的延长,糠椴的基径、色木槭的树高对光照响应较敏感,分别倾向于采用“耐荫策略”和“避荫策略”以适应间伐后变化的环境。间伐对日本落叶松人工林林下更新阔叶木本植物组成和生长的影响具有明显的时间效应;在制定以促进人工林林下树种更新为目标的间伐措施时,应该考虑适当延长间伐间隔,从而保证糠椴和色木槭等阔叶树幼苗的生长,使其进入林冠层,促进形成针阔混交林,实现人工林的可持续发展。.

Post-traumatic stress disorder (PTSD) is a psychiatric disease which leads to a series of anxiety-like behaviors. In this study, we investigated the temporal effects of electroacupuncture (EA) at acupoint ST36 on anxiety-like behaviors and the expression of c-Fos in the anterior cingulate cortex (ACC) in a rat model of PTSD. PTSD was induced by a single prolonged stress procedure comprising three stages: restraint for 2 h, forced swim for 20 min, and pentobarbital sodium anesthesia. EA at acupoint ST36 was performed from 7:00-9:00 once a day for 7 consecutive days. Open field test (OFT) and elevated plus maze (EPM) test were used to assess the success of the model and evaluate anxiety-like behaviors. Immunohistochemistry was used to detect Fos-positive nuclei in the ACC. We observed that EA performed from 7:00-9:00 was associated with significantly more time spent in the center area during the OFT and in the open arm during the EPM, as well as lower corticosterone response compared with that of regular EA (P < 0.05). PTSD rats expressed significantly less c-Fos in the ACC. Timed EA significantly increased c-Fos expression in the ACC. The effect of timed EA acting on PTSD rats was linked to altered neuronal activation in the ACC. Compared to regular EA, timed EA exhibited superior therapeutic effects by attenuating anxiety-like behaviors in PTSD rats. These results emphasize the association between temporal parameters of EA manipulation and acupuncture effects. Timed acupuncture therapy may be a novel therapeutic application in the treatment of PTSD.

The current recommendation is to use daily doses of vitamin C to prevent the occurrence of the complex regional pain syndrome (CRPS) following a distal radius fracture. The study is a synthesis of the four primary studies that examine this issue. These studies have been previously examined in the meta-analysis literature. The incidence of CRPS is lower in patients treated with the vitamin C protocol compared with the control. The significance of the difference varies from P = .02 to P = .13. Our analysis points to the fact that the relative efficacy of vitamin C has decreased over the past 15 years (P < .001). In 2014, the incidence of CRPS in the vitamin C cohort is not statistically different from the incidence in the control group (P = .76). Vitamin C has lost its relative efficacy.

The detection of amplitude modulation (AM) in quiet or in noise improves when the AM carrier is preceded by noise, an effect that has been attributed to the medial olivocochlear reflex (MOCR). We investigate whether this improvement can occur without the MOCR by measuring AM sensitivity for cochlear implant (CI) users, whose MOCR effects are circumvented as a result of the electrical stimulation provided by the CI. AM detection thresholds were measured monaurally for short (50 ms) AM probes presented at the onset (early condition) or delayed by 300 ms (late condition) from the onset of a broadband noise. The noise was presented ipsilaterally, contralaterally and bilaterally to the test ear. Stimuli were processed through an experimental, time-invariant sound processing strategy. On average, thresholds were 4 dB better in the late than in the early condition and the size of the improvement was similar for the three noise lateralities. The pattern and magnitude of the improvement was broadly consistent with that for normal hearing listeners [Marrufo-Pérez et al., 2018, J Assoc Res Otolaryngol 19:147-161]. Because the electrical stimulation provided by CIs is independent from the middle-ear muscle reflex (MEMR) or the MOCR, this shows that mechanisms other than the MEMR or the MOCR can facilitate AM detection in noisy backgrounds.

The amount of meat consumed is having a negative impact on both health and the environment. This study investigated the probability of eating meat and the amount eaten at a meal within different social, temporal and situational contexts. Dietary intake data from 4-day diet diaries of adults (19 years and above) taken from the UK National Diet and Nutrition Survey (2008/9-2013/14) were used for the analysis. Individual eating occasions were identified and the effects of where the food was eaten, with whom, day of the week, age and gender on the probability of eating meat and amount of meat eaten were modelled using general linear mixed models. Each factor showed distinctive effects on the probability of eating meat and the amount consumed. The amount of meat eaten was greater when eating with family members compared to when alone or with other companions. Both the probability and amount of meat eaten in a single eating occasion were higher on Sundays compared to the rest of the week. Eating out (e.g. restaurants/cafes) increased the probability of consuming meat and the amount compared to other situations (e.g. home, work). When considering the factors influencing meat consumption, attention must be paid to the effects of social, temporal, and situational factors as they all work to shape consumption behaviour. This information should be used in the design of interventions and development of policies for the most effective way to reduce meat consumption.

The demands of modern psychophysical studies require precise stimulus delivery and flexible platforms for experimental control. Here, we describe PsyAcoustX, a new, freely available suite of software tools written in the MATLAB(®) environment to conduct psychoacoustics research on a standard PC. PsyAcoustX provides a flexible platform to generate and present auditory stimuli in real time and record users\' behavioral responses. Data are automatically logged by stimulus condition and aggregated in an exported spreadsheet for offline analysis. Detection thresholds can be measured adaptively under basic and complex auditory masking tasks and other paradigms (e.g., amplitude modulation detection) within minutes. The flexibility of the module offers experimenters access to nearly every conceivable combination of stimulus parameters (e.g., probe-masker relations). Example behavioral applications are highlighted including the measurement of audiometric thresholds, basic simultaneous and non-simultaneous (i.e., forward and backward) masking paradigms, gap detection, and amplitude modulation detection. Examples of these measurements are provided including the psychoacoustic phenomena of temporal overshoot, psychophysical tuning curves, and temporal modulation transfer functions. Importantly, the core design of PsyAcoustX is easily modifiable, allowing users the ability to adapt its basic structure and create additional modules for measuring discrimination/detection thresholds for other auditory attributes (e.g., pitch, intensity, etc.) or binaural paradigms.