被认为是罕见的,滑膜炎-痤疮-脓疱病-骨肥大-骨炎(SAPHO)综合征是一个独特的临床实体,皮肤表现和骨关节症状。胸锁和胸肋关节中心的前胸壁疼痛是可以导致其诊断的重要且特征性的临床发现。放射科医生和临床医生必须意识到滑膜炎-痤疮-脓疱病-肥大-骨炎综合征,因为它可以模仿一些更常见的疾病实体,如佩吉特病。我们报道了一个63岁的男性患者,没有明显的病史,他介绍给皮肤科,伴有严重的手掌和足底脓疱病,并伴有多关节痛。计算机断层扫描显示胸锁骨增生,支持SAPHO综合征,非甾体抗炎药治疗后临床症状消退。
Considered rare, the synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome is a distinct clinical entity, associating skin manifestations and osteoarticular symptoms. Anterior chest wall pain centered at sternoclavicular and sternocostal joints is an important and characteristic clinical finding that can lead to its diagnosis. Radiologists and clinicians must be aware of synovitis-acne-pustulosis-hyperostosis-osteitis syndrome as it can mimic some of the more common disease entities such as Paget\'s disease. We report the case of a 63-year-old male patient, with no significant medical history, who presented to the dermatology department, with severe palmar and plantar pustulosis associated with polyarthralgia. Computerized tomography scan showed sternoclavicular hyperostosis, in favor of SAPHO syndrome, with regression of clinical symptoms after non-steroidal anti-inflammatory drug treatment.