surgical exploration

外科探查术
  • 文章类型: Case Reports
    大网膜原发性恶性肿瘤少见,报告不到50例。恶性血管外皮细胞瘤仅构成其中的4例。恶性网膜肿瘤的常见临床表现是腹部肿块和疼痛。我们报告了一名38岁的妇女,她来到医院的急诊科,发现肠梗阻(腹痛,便秘,腹胀,和呕吐),在临床检查中,在她的腹部下半部发现了肿块。在她到达之前,她已经经历了三天的这些症状。在临床检查中,一个大尺寸,在她的腹部下半部发现了坚硬的活动肿块。患者接受了腹部CT扫描,显示存在相当大的,位于腹部和骨盆区域的软组织肿块,对小肠环施加压力,温和的自由腹水。由于病人的急腹症,进行了剖腹探查术,显示大质量的大网膜测量20×20×10厘米,重3公斤。质量,随着网膜,被完全移除,组织病理学证实为恶性血管外皮细胞瘤。
    The greater omentum primary malignant tumors are rare, with less than 50 cases reported. Malignant hemangiopericytomas constitute only four of these cases. The common clinical manifestations of a malignant omental tumor are abdominal mass and pain. We report on a woman 38 years old who came to the hospital\'s emergency department with a finding consisting of intestinal obstruction (abdominal pain, constipation, abdominal distention, and vomiting), and during a clinical examination a mass was discovered in the lower half of her abdomen. She had been experiencing these symptoms for three days before her arrival. During a clinical examination, a large size, hard mobile mass was discovered in the lower half of her abdomen. The patient underwent an abdominal CT scan which indicated the presence of a sizable, soft tissue mass located within the abdominal and pelvic region, exerting pressure on the small bowel loops, with mild free ascites. Due to the patient\'s acute abdomen, an exploration laparotomy was performed, revealing a large mass in the omentum measuring 20×20×10 cm and weighing 3 kg. The mass, along with the omentum, was completely removed, and histopathology confirmed a malignant hemangiopericytoma.
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  • 文章类型: Journal Article
    背景:诱导化疗后局部晚期胰腺癌(LAPC)患者手术的应用正在增加。然而,大多数系列没有报告接受手术探查的患者的总队列;因此,这项单中心研究调查了所有连续接受手术探查的LAPC患者的结局.
    方法:我们进行了回顾性研究,单中心分析包括所有LAPC(荷兰胰腺癌组标准)患者,这些患者在诱导治疗后(2014年1月至2023年6月)接受了治愈性手术探查.主要结果是切除率和诊断时的总生存率(OS)。
    结果:总体而言,127例患者接受了LAPC手术探查,其中100例患者(78.7%)因血管受累(n=11,8.7%)或隐匿性转移(n=16,12.6%)而接受了非治疗性剖腹手术。总体住院/30天死亡率为0.8%,主要发病率为31.3%(切除后的患者:1.0%和33.3%,分别)。总体90天死亡率为5.5%,其中包括3.1%由于疾病进展导致的死亡率.切除与较长的中位OS{29个月(95%置信区间[CI]26-43)和17个月(95%CI11-26);p<0.001}与非治疗性剖腹手术患者相比,相应的5年OS率为28.4%和7.7%。在Cox比例风险回归分析中,只有胰腺体/尾部肿瘤独立预测OS(风险比1.788[95%CI1.042-3.068])。
    结论:此单中心系列发现,选择手术探查的LAPC患者的切除率为78.7%,所有研究患者的死亡率和发病率均较低,切除术后5年OS率为28.4%。
    BACKGROUND: The use of surgery in patients with locally advanced pancreatic cancer (LAPC) following induction chemotherapy is increasing. However, most series do not report on the total cohort of patients undergoing surgical exploration; therefore, this single-center study investigates outcomes among all consecutive patients with LAPC who underwent surgical exploration.
    METHODS: We conducted a retrospective, single-center analysis including all consecutive patients with LAPC (Dutch Pancreatic Cancer Group criteria) who underwent surgical exploration with curative intent (January 2014-June 2023) after induction therapy. Primary outcomes were resection rate and overall survival (OS) from the time of diagnosis.
    RESULTS: Overall, 127 patients underwent surgical exploration for LAPC, whereby 100 patients (78.7%) underwent resection and 27 patients (21.3%) underwent a non-therapeutic laparotomy due to the extent of vascular involvement (n = 11, 8.7%) or occult metastases (n = 16, 12.6%). The overall in-hospital/30-day mortality rate was 0.8% and major morbidity was 31.3% (in patients after resection: 1.0% and 33.3%, respectively). The overall 90-day mortality rate was 5.5%, which included 3.1% mortality due to disease progression. Resection was associated with longer median OS {29 months (95% confidence interval [CI] 26-43) vs. 17 months (95% CI 11-26); p < 0.001} compared with patients undergoing non-therapeutic laparotomy, with corresponding 5-year OS rates of 28.4% and 7.7%. In Cox proportional hazard regression analysis, only pancreatic body/tail tumors independently predicted OS (hazard ratio 1.788 [95% CI 1.042-3.068]).
    CONCLUSIONS: This single-center series found a resection rate of 78.7% in patients with LAPC selected for surgical exploration, with a low risk of mortality and morbidity in all explored patients and a 5-year OS rate after resection of 28.4%.
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  • 文章类型: Case Reports
    硬化性肠系膜炎,一种罕见的影响肠系膜的纤维炎症性疾病,由于其不同的临床表现和未知的病因,提出了诊断挑战。我们介绍了一个50岁的女性,表现为上腹痛和体重减轻,最初怀疑腹部恶性肿瘤。成像显示肠系膜肿块,和组织病理学检查证实密集的淋巴浆细胞浸润伴有骨性纤维化,随着血清IgG4水平升高,指示IgG4相关硬化性肠系膜炎。沙利度胺和泼尼松龙治疗可导致明显的肿块消退和症状改善。我们的病例强调了在腹部肿块的鉴别诊断中考虑硬化性肠系膜炎的重要性,并为这种罕见的疾病提供了潜在的治疗方法。需要进一步研究以阐明其发病机制并优化管理策略。
    Sclerosing mesenteritis, a rare fibroinflammatory disease affecting the mesentery, presents a diagnostic challenge due to its varied clinical manifestations and unknown etiology. We present a case of a 50-year-old female presenting with epigastric pain and weight loss, initially suspected of abdominal malignancy. Imaging revealed a mesenteric mass, and histopathological examination confirmed dense lymphoplasmacytic infiltrate with storiform fibrosis, along with elevated serum IgG4 levels, indicative of IgG4-related sclerosing mesenteritis. Treatment with thalidomide and prednisolone resulted in significant mass regression and symptom improvement. Our case highlights the importance of considering sclerosing mesenteritis in the differential diagnosis of abdominal masses and suggests a potential therapeutic approach for this rare condition. Further research is warranted to elucidate its pathogenesis and optimize management strategies.
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  • 文章类型: Case Reports
    Fournier坏疽的特征是急性坏死性感染。感染可以发生在身体的所有部位,包括阴囊,阴茎,或者会阴,这是一种罕见的疾病,主要在男性中报道,很少在女性中报道。现有文献表明,它可能被低估了,可能导致被忽视的案件。危险因素包括糖尿病,慢性病,和创伤。此例涉及一名52岁女性,有10年糖尿病病史,全身多处皮肤损伤愈合,和皮炎。表现是肛周肿胀,进展为会阴广泛的坏死性软组织感染,诊断出Fournier的坏疽.她接受了广泛的局部清创术,并及时接受了抗生素治疗。患者的临床过程和随后的随访顺利。未控制的糖尿病和皮炎显著增加Fournier坏疽的风险;因此,在患有这种合并症的妇女中应该怀疑它。此案突出表明,需要提高妇女对这种情况的认识和警惕。
    Fournier\'s gangrene is characterized by an acute necrotic infection. The infection can occur in all parts of the body including the scrotum, penis, or perineum, and is a rare condition that is primarily reported in men and seldom in women. Existing literature suggests that it might be underreported, possibly leading to overlooked cases. Risk factors include diabetes, chronic illness, and trauma. This case involves a 52-year-old female with a 10-year medical history of diabetes mellitus, multiple healed skin lesions all over the body, and dermatitis. The presentation was a perianal swelling, which progressed into an extensive necrotizing soft tissue infection of the perineum, making a diagnosis of Fournier\'s gangrene. She underwent wide local debridement and was managed with antibiotics in a timely manner. The patient\'s clinical course and subsequent follow-up were uneventful. Uncontrolled diabetes and dermatitis significantly increase the risk of Fournier\'s gangrene; therefore, it should be suspected in women with such comorbid conditions. This case highlights the need for increased awareness and vigilance regarding this condition among women.
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  • 文章类型: Case Reports
    肾上腺神经鞘瘤是非常罕见的肿瘤,影响约0.2%,起源于肾上腺,由于其非特异性临床特征和与其他肾上腺肿块重叠的放射学特征,提出了诊断挑战。这里,我们报告一例49岁女性,无明显病史,表现为弥漫性腹痛.影像学检查,包括对比增强计算机断层扫描(CECT),右肾上腺内有明确的肿块。鉴于放射学结果不确定和持续的症状,进行了手术探查,导致肿块的识别和切除。显微镜检查,包括免疫组织化学,证实了肿瘤的神经鞘瘤起源。肾上腺神经鞘瘤的最终诊断是在组织病理学检查后确定的。术后,该患者接受抗生素治疗,并在15天后建议随访,在缝合后接受口服抗生素治疗。该病例强调了与肾上腺神经鞘瘤相关的诊断复杂性,并强调了手术干预以进行结论性诊断的必要性。该报告旨在为有限的肾上腺神经鞘瘤文献做出贡献,增强我们对其临床表现的理解,并加强多学科方法在其诊断和管理中的重要性。
    Adrenal schwannomas are exceptionally rare tumors affecting about 0.2%, originating from the adrenal gland, presenting diagnostic challenges due to their nonspecific clinical features and overlapping radiological characteristics with other adrenal masses. Here, we report the case of a 49-year-old female with no significant medical history presenting with diffuse abdominal pain. Imaging studies, including contrast-enhanced computerized tomography (CECT), revealed a well-defined mass within the right adrenal gland. Given inconclusive radiological findings and persistent symptoms, surgical exploration was performed, leading to the identification and resection of the mass. Microscopic examination, including immunohistochemistry, confirmed the schwannomatous origin of the tumor. The final diagnosis of an adrenal schwannoma was established after a histopathological examination. Postoperatively, the patient was treated with antibiotics and discharged on oral antibiotics after suture removal on advised follow-up after 15 days. This case highlights the diagnostic complexities associated with adrenal schwannomas and emphasizes the necessity of surgical intervention for conclusive diagnosis. The report aims to contribute to the limited literature on adrenal schwannomas, enhancing our understanding of their clinical presentation and reinforcing the importance of a multidisciplinary approach in their diagnosis and management.
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  • 文章类型: Case Reports
    腹股沟疝修补术后的股疝是一种不寻常的事件,对医疗保健提供者提出了诊断挑战。腹股沟疝的手术修复通常是成功的,但可能会出现并发症和复发。腹股沟疝修补术后并发股疝的情况很少见,需要仔细的评估和管理。
    方法:一名中年患者因反复腹股沟疼痛和腹股沟区明显隆起而求医。初步成像研究,包括超声和对比增强计算机断层扫描(CT),指向腹股沟疝,导致手术修复的安排。然而,手术期间,外科医生发现了股疝,强调成像技术在准确诊断这些疝类型方面的局限性。
    由于解剖变异和重叠的体征和症状,区分股疝和腹股沟疝可能具有挑战性。先前腹股沟疝修补术的疤痕组织可能会使影像学解释更加复杂。术中探查对于确认诊断和促进适当的手术修复至关重要。
    结论:报告的病例强调了在评估疑似疝气患者时保持警惕的重要性,尤其是那些有腹股沟疝修补术的人.单纯依靠影像学检查会导致误诊,手术期间发现了股疝。医疗保健提供者应意识到股疝的可能性,并进行全面评估,以确保及时干预并改善患者预后。进一步的研究和意识对于优化这种罕见的临床情景至关重要。
    UNASSIGNED: Femoral hernias following inguinal hernia repairs are an unusual occurrence that presents diagnostic challenges for healthcare providers. Surgical repair of inguinal hernias is generally successful, but complications and recurrence can arise. The coexistence of femoral hernias following inguinal hernia repairs is rare, requiring careful evaluation and management.
    METHODS: A middle-aged patient sought medical attention with complaints of recurrent groin pain and a palpable bulge in the inguinal region. Initial imaging studies, including ultrasonography and contrast-enhanced computed tomography (CT), pointed towards an inguinal hernia, leading to the scheduling of surgical repair. However, during the operation, the surgeon discovered a femoral hernia, highlighting the limitations of imaging techniques in accurately diagnosing these hernia types.
    UNASSIGNED: Due to anatomical variations and overlapping signs and symptoms, distinguishing between femoral and inguinal hernias can be challenging. Scar tissue from previous inguinal hernia repairs can further complicate imaging interpretations. Intraoperative exploration becomes crucial to confirm the diagnosis and facilitate proper surgical repair.
    CONCLUSIONS: The reported case emphasizes the importance of maintaining vigilance in evaluating patients with suspected hernias, particularly those with prior inguinal hernia repairs. Relying solely on imaging studies can lead to misdiagnosis, as illustrated by the discovery of a femoral hernia during surgery. Healthcare providers should be aware of the possibility of femoral hernias and conduct comprehensive evaluations to ensure timely intervention and improve patient outcomes. Further research and awareness are essential to optimize the care of such uncommon clinical scenarios.
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  • 文章类型: Journal Article
    背景:腹腔内感染(IAIs)是最常见的外科感染类型,与高相关的发病率和死亡率。近年来,由于使用抗生素,出现了各种耐药细菌,使腹部感染的治疗更具挑战性。早期手术探查可降低腹腔感染患者的死亡率和并发症的发生。然而,关于IAI手术最佳时机的现有证据仍然薄弱.在研究中,我们比较了手术时间对腹腔感染患者的影响,并试图确定手术的最佳时机。
    目的:评估早期与延迟手术探查治疗IAI的疗效,就总死亡率而言。
    方法:使用PubMed进行了系统的文献检索,EMBASE,Cochrane中央控制试验登记册,奥维德,和科学直接。采用系统评价的首选报告项目和Meta分析方法进行系统评价。根据外科手术的时机,我们将文献分为两组:早期手术和延迟手术。对于早期和延迟手术组,在初次手术干预12小时后进行干预,分别。主要结果指标是死亡率。文献检索于2021年5月5日至20日进行。我们还在2021年5月20日搜索了世界卫生组织国际临床试验注册平台搜索门户和ClinicalTrials.gov,以进行正在进行的试验。本研究已在国际前瞻性系统评价登记册上注册。
    结果:我们确定了9个合格的试验比较。对IAIs患者进行早期手术探查(在12小时内进行)显着降低了患者的死亡率和并发症。提高了生存率,缩短了住院时间。
    结论:与延迟手术相比,在12小时内早期手术探查可能对IAIs的治疗更有效。
    BACKGROUND: Intra-abdominal infections (IAIs) is the most common type of surgical infection, with high associated morbidity and mortality rates. In recent years, due to the use of antibiotics, various drug-resistant bacteria have emerged, making the treatment of abdominal infections more challenging. Early surgical exploration can reduce the mortality of patients with abdominal infection and the occurrence of complications. However, available evidence regarding the optimal timing of IAI surgery is still weak. In study, we compared the effects of operation time on patients with abdominal cavity infection and tried to confirm the best timing of surgery.
    OBJECTIVE: To assess the efficacy of early vs delayed surgical exploration in the treatment of IAI, in terms of overall mortality.
    METHODS: A systematic literature search was performed using PubMed, EMBASE, Cochrane Central Register of Controlled Trials, Ovid, and ScienceDirect. The systematic review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-analyses method. Based on the timing of the surgical operation, we divided the literature into two groups: Early surgery and delayed surgery. For the early and delayed surgery groups, the intervention was performed with and after 12 h of the initial surgical intervention, respectively. The main outcome measure was the mortality rate. The literature search was performed from May 5 to 20, 2021. We also searched the World Health Organization International Clinical Trials Registry Platform search portal and ClinicalTrials.gov on May 20, 2021, for ongoing trials. This study was registered with the International Prospective Register of Systematic Reviews.
    RESULTS: We identified nine eligible trial comparisons. Early surgical exploration of patients with IAIs (performed within 12 h) has significantly reduced the mortality and complications of patients, improved the survival rate, and shortened the hospital stay.
    CONCLUSIONS: Early surgical exploration within 12 h may be more effective for the treatment of IAIs relative to a delayed operation.
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  • 文章类型: Case Reports
    睾丸扭转是一种以阴囊内睾丸和精索扭转为特征的疾病,导致静脉回流阻塞和随后的肿胀。如果不及时治疗,扭转可以进展到阻塞动脉血液供应,导致缺血。长期缺血可导致睾丸坏死和生育能力下降。认识到这种情况的紧迫性,及时的诊断和管理至关重要。在这个临床病例中,一名16岁男性在轻微创伤后出现左侧阴囊疼痛。尽管及时就医,寻求治疗的延迟导致不可逆的睾丸坏死。该病例强调了诊断和治疗睾丸扭转的紧迫性,以防止睾丸丢失和生育能力下降等严重后果。它是一个尖锐的提醒,让医疗保健专业人员保持警惕,认识到这种泌尿外科紧急情况,并倡导及时干预以优化患者预后。
    Testicular torsion is a condition characterized by the twisting of the testis and spermatic cord within the scrotum, resulting in the obstruction of venous return and subsequent swelling. If left untreated, the torsion can progress to block the arterial blood supply, leading to ischemia. Prolonged ischemia can result in testicular necrosis and decreased fertility. Recognizing the urgency of this condition, timely diagnosis and management are crucial. In this clinical case, a 16-year-old male presented with left-sided scrotal pain following a minor trauma. Despite prompt medical attention, the delay in seeking treatment resulted in irreversible testicular necrosis. The case emphasizes the urgency of diagnosing and managing testicular torsion to prevent serious consequences such as testicular loss and reduced fertility. It serves as a poignant reminder for healthcare professionals to remain vigilant in recognizing this urological emergency and advocating for timely intervention to optimize patient outcomes.
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  • 文章类型: Case Reports
    脐动脉和静脉导管广泛用于危重新生儿的管理。娇嫩,它们可能会被针头无意中损坏,剪刀,在插入和移除过程中或紧密的荷包缝线。脐动脉导管栓塞是一种罕见且可怕的并发症,迄今报告的病例不到15例。我们描述了一个术语新生儿,其中3.5-Fr脐动脉导管,意外破碎和移位,通过右髂总动脉切开术手术恢复,安全和完全。在避免尝试局部探查的同时直接手术取出脐带导管可能被认为是一线管理。特别是如果血管内设施不可用或无法进入。
    Umbilical arterial and venous catheters are used widely in management of critically ill neonates. Being delicate, they can get inadvertently damaged by needles, scissors, or tight purse-string sutures during insertion and removal. Umbilical artery catheter embolization is a rare and dreaded complication, with less than 15 cases reported to date. We describe a term neonate, in whom a 3.5-Fr umbilical artery catheter, accidentally broken and dislodged, was surgically retrieved through right common iliac arteriotomy, safely and completely. Direct surgical retrieval of umbilical catheters while avoiding attempts at local exploration maybe considered a first line in management, particularly if endovascular facilities are unavailable or inaccessible.
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  • 文章类型: Journal Article
    未经证实:毛黄是儿科人群中一种罕见的胃肠道病理。患者表现出一系列症状,从无症状到腹痛,可触及腹部肿块。一旦诊断,就需要紧急检索,因为延迟诊断可能导致严重的并发症。
    UNASSIGNED:我们在2021年3月至2022年3月期间提供了一系列6例患者,他们在儿童医院就诊并被诊断为胃小黄。对患者进行优化并为手术做好准备。所有患者均接受手术探查,并去除一簇头发。在整个治疗过程中对他们进行了随访,其中三名患者接受了精神病学评估。
    未经证实:毛虫是一种罕见但重要的外科病例,是潜在精神疾病的表现。呈现从无症状的肿块到具有延迟呈现的危及生命的并发症。包括精神病学在内的多学科方法,应进行儿科医生和儿科外科医生。随访是治疗的主要手段,由于不依从性或管理不当,可能会复发。
    UNASSIGNED: Trichobezoar is a rare gastrointestinal pathology in paediatric population. Patients present with a range of symptoms from being asymptomatic to abdominal pain with a palpable abdominal mass. Once diagnosed it warrants urgent retrieval as delayed diagnosis may lead to serious complications.
    UNASSIGNED: We present a series of six cases between March 2021 and March 2022 who presented to Children\'s Hospital and were diagnosed as a case of Gastric Trichobezoars. Patients were optimized and prepared for surgery. All patients underwent Surgical exploration and a tuft of hair were removed. They were followed up throughout the course of treatment and three of the patients underwent psychiatric evaluation.
    UNASSIGNED: Trichobezoar is a rare but important surgical case that is a manifestation of underlying psychiatric ailment. Presentation varies from asymptomatic masses to life threatening complications with delayed presentations. A multi-disciplinary approach including Psychiatric, Paediatrician and Paediatric surgeon should be undertaken. Follow-up is the mainstay of treatment and recurrence may be seen due to non-compliance or inadequate management.
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