surgical decision making

  • 文章类型: Journal Article
    目标:我们的医疗中心实施了一个多学科团队,以改善高危老年人的手术决策。为了使这成为一个以病人为中心的过程,试点项目将患者及其家属/护理人员纳入这些对话.我们的假设是,多学科团队讨论可以改善艰难的手术决策。方法:从2022年1月至6月,我们在退伍军人事务医疗中心为患者及其家人提供了多学科讨论的参与。会议后1-6天进行了半结构化访谈。采用定性混合方法对访谈笔录进行分析。结果:六名患者和护理人员参加了访谈。他们发现讨论有助于提高他们对手术决定的理解。在这些中,50%(6个中的3个)的患者根据讨论改变了对计划手术的决定。结论:在多学科手术决策讨论中包括患者和护理人员,导致一半的患者改变手术计划。这项试点研究证明了所有参与者的接受度和可行性。
    Objective: Our medical center implemented a multidisciplinary team to improve surgical decision making for high-risk older adults. To make this a patient-centric process, a pilot program included the patient and their family/caregiver(s) in these conversations. Our hypothesis is that multidisciplinary team discussions can improve difficult surgical decision making. Methods: From January to June 2022, we offered patients and their family participation in multidisciplinary discussions at a Veterans Affairs medical center. Semistructured interviews were conducted 1-6 days after the meeting. Interview transcripts were analyzed with qualitative mixed-methods approach. Results: Six patients and caregivers participated in the interviews. They found the discussion helpful for improving their understanding of the surgical decision. Out of these, 50% (3 of 6) of the patients changed their decision regarding the planned operation based on the discussion. Conclusion: Including patients and caregiver(s) in multidisciplinary surgical decision-making discussions resulted in half of the patients changing their surgical plans. This pilot study demonstrated both acceptance and feasibility for all participants.
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  • 文章类型: Journal Article
    胶质母细胞瘤的手术决策由于其复杂性和变异性而面临重大挑战。这项研究调查了人工智能(AI)工具在改善胶质母细胞瘤手术的“决策过程”方面的潜力。对文献的系统回顾确定了10项相关研究,主要集中在预测可切除性和手术相关的神经系统结局。AI工具,尤其是植根于影像组学和连接组学,在通过精确的肿瘤分割和肿瘤网络关系预测切除程度方面表现出希望。然而,由于患者相关因素的动态性和不可量化性,他们在预测术后神经系统方面的有效性有限.认识到这些挑战,包括有限的数据集和医疗应用中的可解释性要求,强调标准化的必要性,算法优化,并解决模型性能的变异性,然后在临床环境中进一步验证。虽然AI有潜力,它目前不具备模仿有经验的神经外科医生在胶质母细胞瘤手术的综合方法中使用的细微差别决策过程的能力.
    Surgical decision-making for glioblastoma poses significant challenges due to its complexity and variability. This study investigates the potential of artificial intelligence (AI) tools in improving \"decision-making processes\" for glioblastoma surgery. A systematic review of literature identified 10 relevant studies, primarily focused on predicting resectability and surgery-related neurological outcomes. AI tools, especially rooted in radiomics and connectomics, exhibited promise in predicting resection extent through precise tumor segmentation and tumor-network relationships. However, they demonstrated limited effectiveness in predicting postoperative neurological due to dynamic and less quantifiable nature of patient-related factors. Recognizing these challenges, including limited datasets and the interpretability requirement in medical applications, underscores the need for standardization, algorithm optimization, and addressing variability in model performance and then further validation in clinical settings. While AI holds potential, it currently does not possess the capacity to emulate the nuanced decision-making process utilized by experienced neurosurgeons in the comprehensive approach to glioblastoma surgery.
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  • 文章类型: Journal Article
    背景:手的先天性异常会影响功能和外观,给家庭带来了巨大的心理负担,尤其是父母。婴儿期手术可以预防后期残疾,但在心理调整或治疗满意度方面,父母参与这些决定的重要性鲜为人知。
    目的:了解父母对参与孩子肢体异常手术的看法,以及他们对医疗保健专业人员支持的偏好。结果应导致推荐的干预措施,以改善家庭对儿童状况的调整。
    方法:定性数据是从35名接受先天性手畸形重建手术的儿童(年龄为24.89±9.26个月)的父母(65.7%的母亲)的半结构化秘密自我报告访谈中收集的;访谈与术后1个月的随访相吻合。父母的年龄不等,性别,教育背景,经济地位,和异常类型。数据分析参考了Colaizzi的现象学方法。
    结果:父母的担忧被合并为三个主题:对父母参与手术决策的态度;父母参与手术决策的状况;以及需要帮助和支持。
    结论:一些父母很乐意将手术决定完全留给医务人员,但大多数人更喜欢积极参与,并对他们缺乏包容性感到失望。当父母和大家庭能够获得专业知识时,婴儿期先天性畸形手术的最大收益就可以实现,技能,鼓励,以及医疗保健提供者的心理支持。
    BACKGROUND: A congenital anomaly of the hand can affect both function and appearance, and places a stressful psychological burden on the family, especially parents. Surgery during infancy may prevent later disabilities, but little is known of the importance of parents\' involvement in these decisions in terms of psychological adjustment or treatment satisfaction.
    OBJECTIVE: To understand parents\' perceptions of involvement in their child\'s surgery for limb anomaly, and their preferences for the support of healthcare professionals. Results should lead to recommended interventions to improve familial adjustment to the child\'s condition.
    METHODS: Qualitative data was collected from semi-structured confidential self-reported interviews of 35 parents (65.7 % mothers) of children who had received reconstructive surgery for congenital hand anomaly (at age 24.89 ± 9.26 months); interviews were coincident with the 1-month postoperative follow-up. The parents ranged in age, gender, educational background, economic status, and type of anomaly. Data analysis referenced Colaizzi\'s phenomenological approach.
    RESULTS: The concerns of the parents were consolidated into three themes: attitudes toward Parental involvement in surgical decision-making; status of parental involvement in Surgical decision-making; and need for help and support.
    CONCLUSIONS: Some parents were comfortable leaving surgical decisions entirely to the medical staff, but most preferred active participation and were disappointed at their lack of inclusion. The maximum benefit from surgery for congenital abnormalities in infancy is achieved when the parents and extended families have access to the expertise, skills, encouragement, and psychological support of healthcare providers.
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  • 文章类型: Journal Article
    目的:报告我们在持续性肢端肥大症的护理轨迹中使用18F-氟-乙基-酪氨酸(FET)正电子发射断层扫描(PET-CT)与磁共振成像(MRI)(FET-PET/MRICR)共配准的计算机断层扫描(PET-CT)的经验。
    方法:前瞻性病例系列。
    方法:10例肢端肥大症控制不充分的患者向我们的团队推荐手术方案。
    方法:FET-PET/MRICR用于支持决策,如果单独的MRI和多学科团队评估不能提供足够的清晰度来进行手术。
    结果:FET-PET/MRICR在所有患者中均显示可疑的(对侧)鞍区示踪剂摄取。在5例患者中,FET-PET/MRICR与常规MRI完全一致,一名患者部分一致。FET-PET/MRICR在其他四名患者中发现了提示新的病灶。对9例患者进行了手术再探查(旨在全切除(6),剔除(2),诊断(1)),一名患者接受了放射治疗。9例手术患者中有7例(78%)的FET-PET/MRICR结果在术中得到证实,在组织学上也有6例(67%)。8例患者中IGF-1显著下降(89%)。所有患者均显示临床改善。在三名患者中实现了完全的生化缓解(预计完全切除可行的手术的50%)。5例患者的生化改善,1例患者的生化没有变化。无永久性并发症发生。六个月的时候,6例(67%)患者达到了最佳结局(术前预期目标,无永久性并发症),中间结局(目标未实现,但没有并发症)在其他三名患者中。
    结论:在MRI上没有明确手术目标的持续肢端肥大症患者中,FET-PET/MRICR是一种新的示踪剂,可提供其他信息以帮助多学科垂体团队做出决策。
    OBJECTIVE: To report our experience with 18F-fluoro-ethyl-tyrosine (FET) positron emission tomography-computed tomography (PET-CT) co-registered with magnetic resonance imaging (MRI) (FET-PET/MRICR) in the care trajectory for persistent acromegaly.
    METHODS: Prospective case series.
    METHODS: Ten patients with insufficiently controlled acromegaly referred to our team to evaluate surgical options.
    METHODS: FET-PET/MRICR was used to support decision-making if MRI alone and multidisciplinary team evaluation did not provide sufficient clarity to proceed to surgery.
    RESULTS: FET-PET/MRICR showed suspicious (para)sellar tracer uptake in all patients. In five patients FET-PET/MRICR was fully concordant with conventional MRI, and in one patient partially concordant. FET-PET/MRICR identified suggestive new foci in four other patients. Surgical re-exploration was performed in nine patients (aimed at total resection (6), debulking (2), diagnosis (1)), and one patient underwent radiation therapy. In 7 of 9 (78%) operated patients FET-PET/MRICR findings were confirmed intraoperatively, and in six (67%) also histologically. IGF-1 decreased significantly in eight patients (89%). All patients showed clinical improvement. Complete biochemical remission was achieved in three patients (50% of procedures in which total resection was anticipated feasible). Biochemistry improved in five and was unchanged in one patient. No permanent complications occurred. At six months, optimal outcome (preoperative intended goal achieved without permanent complications) was achieved in six (67%) patients and an intermediate outcome (goal not achieved, but no complications) in the other three patients.
    CONCLUSIONS: In patients with persisting acromegaly without a clear surgical target on MRI, FET-PET/MRICR is a new tracer to provide additional information to aid decision-making by the multidisciplinary pituitary team.
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  • 文章类型: Journal Article
    尺神经病变的治疗仍不清楚,因为既没有共识指南,也没有令人信服的数据来告知最佳治疗。确定从手术中受益最多的轻度至中度患者是具有挑战性的,因为他们的症状可能是微妙的且不那么使人衰弱。这项研究调查了McGowan轻度或中度肘管综合征(CuTS)患者手术干预的预测因素。
    这是一项机构审查委员会批准的研究。从2016年3月至2022年7月评估的患者如果被诊断为McGowan轻度或中度CuTS并同时接受电诊断和超声评估,则包括在内。患者人口统计学,症状表现,并对临床和诊断性检查结果进行分析。使用学生t检验分析变量,Mann-WhitneyU测试,或皮尔森卡方检验。多变量逻辑回归用于评估协变量和手术的关联。
    确定了73名患者和103个肘部。平均年龄和体重指数分别为51岁和26.9岁。大多数病人是男性,右撇子,优势手单方面有症状。手术治疗了26个肘部。通过手术治疗进行的双变量分析表明,与肘部相比,接受手术的患者更经常具有阳性的电诊断结果,包括运动神经传导速度<50m/s和前臂传导速度差>10m/s。59例被归类为电诊断正常。在电诊断正常病例中,29在超声上有CuTS阳性发现。Logistic回归模型显示,电诊断重症病例接受手术治疗的几率是正常病例的3.7倍(调整后的优势比,3.7;95%CI,1.11-12.6;P=0.03)。
    确定应接受手术治疗的患者的客观发现差异不多。除了测试结果,来自患者的更多主观发现,如患者报告的损伤程度,可能能够弥补手术决策中的这一差距.
    这项研究有助于轻度和中度CuTS的治疗决策。
    UNASSIGNED: The management of ulnar neuropathy remains unclear as there are neither consensus guidelines nor compelling data available to inform optimal treatment. Identifying patients in the mild-to-moderate group that would benefit most from surgery is challenging as their symptoms can be subtle and less debilitating. This study investigated predictors of surgical intervention among patients presenting with McGowan mild or moderate cubital tunnel syndrome (CuTS).
    UNASSIGNED: This is an institutional review board-approved study. Patients evaluated from March 2016 to July 2022 were included if they were diagnosed with McGowan mild or moderate CuTS and underwent concurrent electrodiagnostic and ultrasound evaluations. Patient demographics, symptom presentation, and clinical and diagnostic test findings were analyzed. Variables were analyzed using Student t test, Mann-Whitney U test, or Pearson\'s chi-square test. Multivariable logistic regression was used to assess the association of covariates and surgery.
    UNASSIGNED: Seventy-three patients and 103 elbows were identified. The mean age and body mass index were 51 years and 26.9, respectively. Most patients were men, right-handed, and unilaterally symptomatic in the dominant hand. Twenty-six elbows were surgically treated. Bivariable analyses by surgical treatment showed that patients who underwent surgery more often had positive electrodiagnostic findings including motor nerve conduction velocity <50 m/s and a >10 m/s conduction velocity difference across the forearm compared with elbow. Fifty-nine cases were categorized as electrodiagnostically normal. Of the electrodiagnostically normal cases, 29 had positive findings of CuTS on ultrasound. Logistic regression model showed that electrodiagnostically severe cases had 3.7 times higher odds of being surgically treated than normal counterparts (adjusted odds ratio, 3.7; 95% CI, 1.11-12.6; P = .03).
    UNASSIGNED: Not many differences in objective findings identify patients who should receive operative treatment. In addition to test results, more subjective findings from patients such as patient-reported level of impairment may be able to bridge this gap in surgical decision making.
    UNASSIGNED: This study contributes to treatment decision making for mild and moderate CuTS.
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  • 文章类型: Journal Article
    背景:国家手术质量改进计划手术风险计算器(SRC)估计了术后并发症的风险。这项荟萃分析评估了SRC在头颈部手术领域的疗效。
    方法:一项系统评价确定了将SRC的预测与头颈部手术后观察到的结果进行比较的研究。使用受试者工作特征曲线(AUC)和Brier评分评估预测准确性。
    结果:纳入9项研究,共1774名患者。SRC低估了所有结局的风险(包括任何并发症[观察(ob)=35.9%,预测(pr)=21.8%]和严重并发症[ob=28.7%,pr=17.0%]),除了死亡率(ob=0.37%,pr=1.55%)。观察到的停留时间是预测长度的两倍以上(p<0.02)。仅对术后肺炎(AUC=0.778)和尿路感染(AUC=0.782)进行区分是可以接受的。所有结果的预测准确性都很低(Brier评分≥0.01),并且对于有和没有游离皮瓣重建的患者具有可比性。
    结论:SRC是预测头颈部手术结果的无效工具。
    BACKGROUND: The National Surgical Quality Improvement Program surgical risk calculator (SRC) estimates the risk for postoperative complications. This meta-analysis assesses the efficacy of the SRC in the field of head and neck surgery.
    METHODS: A systematic review identified studies comparing the SRC\'s predictions to observed outcomes following head and neck surgeries. Predictive accuracy was assessed using receiver operating characteristic curves (AUCs) and Brier scoring.
    RESULTS: Nine studies totaling 1774 patients were included. The SRC underpredicted the risk of all outcomes (including any complication [observed (ob) = 35.9%, predicted (pr) = 21.8%] and serious complication [ob = 28.7%, pr = 17.0%]) except mortality (ob = 0.37%, pr = 1.55%). The observed length of stay was more than twice the predicted length (p < 0.02). Discrimination was acceptable for postoperative pneumonia (AUC = 0.778) and urinary tract infection (AUC = 0.782) only. Predictive accuracy was low for all outcomes (Brier scores ≥0.01) and comparable for patients with and without free-flap reconstructions.
    CONCLUSIONS: The SRC is an ineffective instrument for predicting outcomes in head and neck surgery.
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  • 文章类型: Journal Article
    目的:回顾性研究退变性腰椎管狭窄症(DLSS)和严重整体矢状面失衡的老年患者接受不同程度融合后的临床和影像学结果。
    方法:共纳入214例DLSS和重度矢状面失衡患者。矢状失衡综合征被定义为严重的失代偿的放射学整体矢状失衡,伴有以下症状:自然姿势的严重背痛消失或在支撑位置显着缓解,ODI评分>40%和动态矢状面失衡的生活残疾。其中,发现有矢状面失衡综合征的54例患者,并进行了腰椎减压及长胸腰椎融合术(A组)或短腰椎融合术(B组)。选择30例无矢状面失衡综合征患者行腰椎短减压融合术作为对照组(C组)。
    结果:与没有这种诊断的患者相比,矢状面失衡综合征患者的椎管旁肌肉变性更多,矢状面失衡代偿潜能更低(胸椎后凸和骨盆倾斜更小)。术后比较显示,在最后的随访中,A组和C组的整体矢状位显着恢复,平衡和生活质量改善。随访期间发现B组中的6例患者和A组中的1例患者有近端交界并发症。
    结论:我们的结果表明,矢状面失衡综合征的DLSS患者在腰椎减压和短融合术后的生活质量和近端交界并发症方面的手术效果较差。
    OBJECTIVE: To retrospectively investigate the postoperative clinical and radiographic outcomes in elderly patients with degenerative lumbar spinal stenosis (DLSS) and severe global sagittal imbalance who underwent different fusion levels.
    METHODS: A total of 214 patients with DLSS and severe global sagittal imbalance were included. Sagittal imbalance syndrome was defined as the severe decompensated radiographic global sagittal imbalance accompanied with the following symptoms: severe back pain in naturel posture that disappears or significantly relieves in support position, living disability with ODI score > 40% and dynamic sagittal imbalance. Thereinto, 54 patients were found with sagittal imbalance syndrome and were performed the lumbar decompression with a long thoracolumbar fusion (Group A) or a short lumbar fusion (Group B). Thirty patients without sagittal imbalance syndrome who underwent short lumbar decompression and fusion were selected as the control (Group C).
    RESULTS: Patients with sagittal imbalance syndrome were detected to have more paraspinal muscle degeneration and less compensatory potentials for sagittal imbalance (smaller thoracic kyphosis and larger pelvic tilt) than those without this diagnosis. Postoperative comparisons revealed significant restoration of global sagittal alignment and balance and improvement of living quality in Groups A and C at the final follow-up. Six patients in Group B and one in Group A were found to have proximal junctional complication during follow-up.
    CONCLUSIONS: Our results indicated that DLSS patients with sagittal imbalance syndrome had inferior surgical outcomes in terms of living quality and proximal junctional complication after lumbar decompression with a short fusion.
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  • 文章类型: Journal Article
    方法:对前瞻性收集的数据进行回顾性分析。
    目的:比较无神经功能缺损的胸腰椎爆裂骨折(TLBF)专家小组与实际脊柱外科医生的决策,并分析哪些因素影响手术决策。
    方法:本研究是一项针对TL骨折的前瞻性观察性研究的子分析。22位专家被要求检查183次CT扫描,并建议对每个骨折进行治疗。专家建议是基于射线照相审查。
    结果:专家小组和现实世界的外科医生在手术方面的总体一致性为63.2%。在36.8%的病例中,专家小组推荐了在实际情况下未进行的手术.相反,在专家小组建议非手术治疗的情况下,只有38.6%接受了非手术治疗,61.4%接受了手术。对A3和A4骨折的单独分析显示,专家小组建议对30%的A3损伤和68%的A4损伤进行手术。然而,61%的A3和A4骨折患者在现实世界中接受了手术。多变量分析表明,PLC损伤的确定性增加1%导致专家小组的手术推荐增加4%,而在现实世界中接受手术的可能性增加了2%。
    结论:专家小组和实际治疗外科医生之间的外科决策各不相同。A3/A4爆裂性骨折的差异似乎不太明显,这使该组特定的骨折成为真正的挑战,而与专业知识水平无关。
    METHODS: Retrospective analysis of prospectively collected data.
    OBJECTIVE: To compare decision-making between an expert panel and real-world spine surgeons in thoracolumbar burst fractures (TLBFs) without neurological deficits and analyze which factors influence surgical decision-making.
    METHODS: This study is a sub-analysis of a prospective observational study in TL fractures. Twenty two experts were asked to review 183 CT scans and recommend treatment for each fracture. The expert recommendation was based on radiographic review.
    RESULTS: Overall agreement between the expert panel and real-world surgeons regarding surgery was 63.2%. In 36.8% of cases, the expert panel recommended surgery that was not performed in real-world scenarios. Conversely, in cases where the expert panel recommended non-surgical treatment, only 38.6% received non-surgical treatment, while 61.4% underwent surgery. A separate analysis of A3 and A4 fractures revealed that expert panel recommended surgery for 30% of A3 injuries and 68% of A4 injuries. However, 61% of patients with both A3 and A4 fractures received surgery in the real world. Multivariate analysis demonstrated that a 1% increase in certainty of PLC injury led to a 4% increase in surgery recommendation among the expert panel, while a .2% increase in the likelihood of receiving surgery in the real world.
    CONCLUSIONS: Surgical decision-making varied between the expert panel and real-world treating surgeons. Differences appear to be less evident in A3/A4 burst fractures making this specific group of fractures a real challenge independent of the level of expertise.
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  • 文章类型: Journal Article
    肱骨近端骨折(PHFs)可导致老年和多发性创伤患者的功能下降。PHF的治疗是从业者之间许多争论和差异很大的领域。
    我们调查了骨科创伤(OT)和肩肘部(SE)外科医生,以评估使用切开复位内固定术(ORIF)治疗急性PHF时术后方案的差异,髓内钉(IMN),或半或反向肩关节成形术(rTSA)。
    我们在2018年8月至2019年4月期间向三个OT和SE协会分发了一项基于网络的调查。问题包括实践特征,负重的标准术后方案,提升,和治疗方式的运动范围(ROM),以及影响模态和术后方案决策的因素。我们比较了亚专业。
    239名外科医生[100(42.2%)OT,118(49.8%)SE]完成了调查。OT更有可能允许即时ROM,提升,髓内钉(IMN)后的承重,采用锁定钢板(ORIF)的切开复位内固定,或关节成形术(所有p<0.025),并允许IMN和关节成形术后更早不受限制地使用四肢(分别为p=0.001,p=0.021)。如果对侧上肢受伤或需要受伤的手臂进行工作或日常生活活动,则OT更有可能考虑对PHF进行手术(所有p<0.026)。亚专科在影响其术后方案的因素上没有显着差异。OT首选IMN和SE外科医生首选rTSA,以允许立即不受限制的术后负重,ROM,或提升(所有p<0.001)。
    在治疗PHF时,创伤和SE外科医生的术后方案存在显着差异。在治疗PHFs患者时,应进一步研究术后方案,以平衡手术结果和功能下降的风险。
    UNASSIGNED: Proximal humerus fractures (PHFs) can lead to functional decline in geriatric and polytraumatized patients. Treatment of PHFs is an area of much debate and much variability between practitioners.
    UNASSIGNED: We surveyed orthopedic trauma (OT) and shoulder and elbow (SE) surgeons to evaluate differences in postoperative protocols when treating acute PHFs with open reduction internal fixation (ORIF), intramedullary nailing (IMN), or hemi or reverse shoulder arthroplasty (rTSA).
    UNASSIGNED: We distributed a web-based survey to three OT and SE associations between August 2018-April 2019. Questions included practice characteristics, standard postoperative protocols for weight-bearing, lifting, and range of motion (ROM) by treatment modality, and factors affecting modality and postoperative protocol decisions. We compared the subspecialties.
    UNASSIGNED: 239 surgeons [100 (42.2 %) OT, 118 (49.8 %) SE] completed the survey. OT were more likely to allow immediate ROM, lifting, and weight bearing following intramedullary nailing (IMN), open reduction internal fixation with a locking plate (ORIF), or arthroplasty (all p < 0.025), and to allow earlier unrestricted use of the extremity following IMN and arthroplasty (p = 0.001, p = 0.021 respectively). OT were more likely to consider operating on a PHF if there was contralateral upper extremity injury or need of the injured arm for work or activities of daily living (all p < 0.026). The subspecialties did not differ significantly on factors affecting their postoperative protocols. OT preferred IMN and SE surgeons preferred rTSA for allowing immediate unrestricted postoperative weight bearing, ROM, or lifting (all p < 0.001).
    UNASSIGNED: There are significant differences in postoperative protocols between trauma and SE surgeons when treating PHFs. Postoperative protocols should be further studied to balance surgical outcomes and the risks of functional decline when treating patients with PHFs.
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  • 文章类型: Journal Article
    观察患者与临床医生的沟通,以了解选择单侧乳腺癌患者进行对侧预防性乳房切除术(CPM)的根本原因,尽管缺乏生存益处,危害的风险,以及手术指南和临床医生表达的注意事项。
    WORDS是一项前瞻性研究,旨在探索患者与临床医生的沟通和患者的决策。参与者通过可下载的移动应用程序记录临床访问。我们分析了22名患者的44条记录:9名选择CPM的患者,8人考虑了CPM,但决定反对,和5个从未考虑过CPM的人。我们使用归纳法分析结合建构主义扎根理论方法。
    接受CPM的决定是由患者驱动的,并且被认为CPM是最积极的,因此最安全,治疗方案可用。这些决定主要不是由与临床医生对话的内容决定的,但根据患者家族的癌症史,他们在亲人中与癌症的第一手经验,害怕他们的孩子,和对癌症复发的焦虑。
    认为CPM是最安全的,最具侵略性的选择会强烈影响患者,尽管科学证据相反。解决高CPM率的未来努力应集中在患者驱动的决策和与癌症相关的恐惧上。
    UNASSIGNED: Observe patient-clinician communication to gain insight about the reasons underlying the choice of patients with unilateral breast cancer to undergo contralateral prophylactic mastectomy (CPM), despite lack of survival benefit, risk of harms, and cautions expressed by surgical guidelines and clinicians.
    UNASSIGNED: WORDS is a prospective study that explored patient-clinician communication and patient decision making. Participants recorded clinical visits through a downloadable mobile application. We analyzed 44 recordings from 22 patients: 9 who chose CPM, 8 who considered CPM but decided against it, and 5 who never considered CPM. We used abductive analysis combined with constructivist grounded theory methods.
    UNASSIGNED: Decisions to undergo CPM are patient-driven and motivated by perceptions that CPM is the most aggressive, and therefore safest, treatment option available. These decisions are shaped not primarily by the content of conversations with clinicians, but by the history of cancer in patients\' families, their own first-hand experiences with cancers among loved ones, fear for their children, and anxiety about cancer recurrence.
    UNASSIGNED: The perception that CPM is the safest, most aggressive option strongly influences patients, despite scientific evidence to the contrary. Future efforts to address high CPM rates should focus on patient-driven decision making and cancer-related fears.
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