surgeries

手术
  • 文章类型: Journal Article
    目的:我们评估了支持术中切换的标准化EHR整合切换报告的有效性和可实施性。
    方法:一项干预前研究用于比较非结构化注释(预)到结构化,标准化的EHR集成切换报告(后)。参与者包括参与术中交接的麻醉临床医生。采用混合方法,在一般意见的支持下,阴影,调查,和采访。
    结果:一百五十一次术中永久性移交(78个前,73个职位)被包括在内。干预后队列中百分之百的参与者使用了该报告。与非结构化相比,使用EHR集成切换报告的结构化切换导致:(1)有关气道管理的信息传输显着增加(55%-78%,P<.001),术中过程(63%-86%,P<.001),和潜在的担忧(64%-88%,P<.001);(2)临床医生满意度评分显着提高,关于信息的清晰度和简洁性(4.5-4.7,P=0.002),信息传递(3.8-4.2,P=.011),以及发送方(3.3-2.5,P<.001)和接收方(3.2-2.4,P<.001)报告的错误较少;(3)切换持续时间显着减少(326.2-262.3s,P=.016)。临床医生发现该报告的实施非常可接受,适当,并且可行,但指出了一些需要改进的地方,以增强其可用性和在术中工作流程中的整合。
    结论:标准化的EHR集成切换报告确保了术中切换的有效性和效率,一致的格式-促进最新和相关的术中信息传递;减少错误的机会;并简化口头交流。交接标准化可以促进安全和高质量的术中护理。
    OBJECTIVE: We evaluated the effectiveness and implementability of a standardized EHR-integrated handoff report to support intraoperative handoffs.
    METHODS: A pre-post intervention study was used to compare the quality of intraoperative handoffs supported by unstructured notes (pre) to structured, standardized EHR-integrated handoff reports (post). Participants included anesthesia clinicians involved in intraoperative handoffs. A mixed-method approach was followed, supported by general observations, shadowing, surveys, and interviews.
    RESULTS: One hundred and fifty-one intraoperative permanent handoffs (78 pre, 73 post) were included. One hundred percent of participants in the post-intervention cohort utilized the report. Compared to unstructured, structured handoffs using the EHR-integrated handoff report led to: (1) significant increase in the transfer of information about airway management (55%-78%, P < .001), intraoperative course (63%-86%, P < .001), and potential concerns (64%-88%, P < .001); (2) significant improvement in clinician satisfaction scores, with regards to information clarity and succinctness (4.5-4.7, P = .002), information transfer (3.8-4.2, P = .011), and opportunities for fewer errors reported by senders (3.3-2.5, P < .001) and receivers (3.2-2.4, P < .001); and (3) significant decrease in handoff duration (326.2-262.3 s, P = .016). Clinicians found the report implementation highly acceptable, appropriate, and feasible but noted a few areas for improvement to enhance its usability and integration within the intraoperative workflow.
    CONCLUSIONS: A standardized EHR-integrated handoff report ensures the effectiveness and efficiency of intraoperative handoffs with its structured, consistent format that-promotes up-to-date and pertinent intraoperative information transfer; reduces opportunities for errors; and streamlines verbal communication. Handoff standardization can promote safe and high-quality intraoperative care.
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  • 文章类型: Journal Article
    目的:老年Black手术患者的围手术期心理健康与不良手术结果相关;然而,缺乏基于证据的围手术期干预措施。我们的两个研究目标包括:第一,检查影响有心理健康问题的老年布莱克手术患者围手术期护理经验的因素,第二,确定文化适应的围手术期心理健康干预的设计和实施要求。
    方法:我们对年龄较大的Black患者进行了六个重点小组(n=15;≥50岁;过去5年内的手术和/或对心理健康研究的兴趣;痛苦史,焦虑,或抑郁症应对手术/住院/)来自大型学术医疗中心。我们聘请了学习伙伴,包括干预主义者和社区成员,收集有关干预和实施需求的见解。我们采用了一种混合的归纳-演绎主题方法,使用开放编码和国家少数民族健康与健康差异研究框架研究所。
    结果:患者报告说,在围手术期护理期间,他们的心理健康和长期心理健康结果没有得到适当考虑。感知到的压力源包括使用精神保健服务的人际和结构性障碍,临床医生在护理中的治疗偏见和年龄歧视,以及缺乏医疗保健专业联系/资源。患者使用了各种应对策略,包括谈话疗法,信仰/灵性,和家人和朋友。
    结论:这项研究为老年Black手术患者的经验提供了宝贵的见解,并为开发个性化的围手术期心理健康干预措施以支持他们的健康提供了关键要素。during,手术后。我们的研究结果表明,需要针对个人/行为和人际关系水平的以患者为中心和文化适应的干预措施。了解文化适应框架,我们提出了一种整合心理和药理成分的多组分干预措施。
    OBJECTIVE: Perioperative mental health of older Black surgical patients is associated with poor surgical outcomes; however, evidence-based perioperative interventions are lacking. Our two study objectives included: first, examine factors affecting perioperative care experiences of older Black surgical patients with mental health problems, and second, ascertain design and implementation requirements for a culturally-adapted perioperative mental health intervention.
    METHODS: We conducted six focus groups with older Black patients (n = 15; ≥50 years; surgery within the past 5 years and/or interest in mental health research; history of distress, anxiety, or depression coping with surgery/hospitalization/) from a large academic medical center. We engaged study partners, including interventionists and community members, to gather insights on intervention and implementation needs. We followed a hybrid inductive-deductive thematic approach using open coding and the National Institute on Minority Health and Health Disparities Research Framework.
    RESULTS: Patients reported that their psychological well-being and long-term mental health outcomes were not appropriately considered during perioperative care. Perceived stressors included interpersonal and structural barriers to using mental healthcare services, clinician treatment biases and ageism in care, and lack of healthcare professional connections/resources. Patients utilized various coping strategies, including talk therapy, faith/spirituality, and family and friends.
    CONCLUSIONS: This study offers valuable insights into the experiences of older Black surgical patients and the critical elements for developing a personalized perioperative mental health intervention to support their well-being before, during, and after surgery. Our findings demonstrated a need for a patient-centered and culturally adapted intervention targeting the individual/behavioral and interpersonal levels. Informed by the cultural adaptation framework, we propose a multi-component intervention that integrates psychological and pharmacological components.
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  • 文章类型: Journal Article
    背景:截至2022年,患者遵守术后指南可以将腹腔镜腹部手术后的并发症风险降低高达52.4%。随着各种术前教育干预措施(POEI)的可用性,了解哪些POEI可以改善整个程序的患者预后。
    目的:本研究旨在通过系统回顾文献中报道的所有POEI来确定哪种POEI对患者预后最有效。
    方法:总共,4753篇调查各种POEI的文章(例如,视频,介绍,移动应用程序,和一对一的教育或辅导)是从PubMed收集的,Embase,和Scopus数据库。纳入标准为接受腹部腹腔镜手术的成年患者,随机对照试验,以及提供术后结果的研究。排除标准包括未以英文发表且无结果报告的研究。标题和摘要及全文文章与POEI随机对照研究是基于上述标准通过盲法筛选,使用Covidence(Veritas健康创新)进行双重审查。通过Cochrane偏差风险工具评估研究质量。对收录的文章进行了教育内容分析,干预时机,干预类型,和适合特定手术的术后结果。
    结果:只有17项研究符合我们的标准,1831例患者接受腹腔镜胆囊切除术,减肥手术(胃旁路和胃袖),还有结肠切除术.总的来说,15项研究报告了至少1名患者术后结果的统计学显着改善。根据Cochrane标准,这些研究均未发现总体偏倚风险较高。总的来说,41%(7/17)的纳入研究使用直接个人教育改善了几乎所有手术类型的结果,虽然教育视频对焦虑的影响最大,恶心,术后疼痛(P<0.01)。直接团体教育显示体重显着改善,BMI,锻炼,33%(2/6)的腹腔镜胃旁路术研究中出现抑郁症状。
    结论:直接教育(以个人或团体为基础)对术后腹腔镜手术结局有积极影响。
    背景:PROSPEROCRD42023438698;https://www.crd.约克。AC.uk/prospro/display_record.php?RecordID=438698。
    BACKGROUND: As of 2022, patient adherence to postoperative guidelines can reduce the risk of complications by up to 52.4% following laparoscopic abdominal surgery. With the availability of various preoperative education interventions (POEIs), understanding which POEI results in improvement in patient outcomes across the procedures is imperative.
    OBJECTIVE: This study aims to determine which POEI could be the most effective on patient outcomes by systematically reviewing all the POEIs reported in the literature.
    METHODS: In total, 4753 articles investigating various POEIs (eg, videos, presentations, mobile apps, and one-on-one education or coaching) were collected from the PubMed, Embase, and Scopus databases. Inclusion criteria were adult patients undergoing abdominal laparoscopic surgery, randomized controlled trials, and studies that provided postoperative outcomes. Exclusion criteria included studies not published in English and with no outcomes reported. Title and abstract and full-text articles with POEI randomized controlled studies were screened based on the above criteria through a blinded, dual review using Covidence (Veritas Health Innovation). Study quality was assessed through the Cochrane Risk of Bias tool. The included articles were analyzed for educational content, intervention timing, intervention type, and postoperative outcomes appropriate for a particular surgery.
    RESULTS: Only 17 studies matched our criteria, with 1831 patients undergoing laparoscopic cholecystectomy, bariatric surgery (gastric bypass and gastric sleeve), and colectomy. In total, 15 studies reported a statistically significant improvement in at least 1 patient postoperative outcome. None of these studies were found to have an overall high risk of bias according to Cochrane standards. In total, 41% (7/17) of the included studies using direct individual education improved outcomes in almost all surgery types, while educational videos had the greatest statistically significant impact for anxiety, nausea, and pain postoperatively (P<.01). Direct group education demonstrated significant improvement in weight, BMI, exercise, and depressive symptoms in 33% (2/6) of the laparoscopic gastric bypass studies.
    CONCLUSIONS: Direct education (individual or group based) positively impacts postoperative laparoscopic surgery outcomes.
    BACKGROUND: PROSPERO CRD42023438698; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=438698.
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  • 文章类型: Journal Article
    背景和目的整容手术是一个主要集中在保存,重建,或通过手术和治疗方法改善个体的身体外观。这种专业化包括各种干预措施,都是手术,比如眼睑成形术,隆鼻,和隆胸,非手术,包括化学剥离等程序,肉毒杆菌注射,和真皮填充物。这项研究旨在评估接受美容手术和非手术美容程序,以及不接受Jazan人群的原因。沙特阿拉伯。方法这项横断面调查研究是在Jazan的一般人群中进行的。沙特阿拉伯,2023年7月至8月。使用GoogleForms创建了在线自我管理问卷,并通过社交媒体分发。采用阿拉伯语翻译的接受整容手术量表(ACSS)测量接受。结果接受整容手术的平均得分为62.1±25.9,而接受非手术治疗的平均得分为63.7±24.5。参与和丧偶的参与者对整容手术的平均接受度得分较高,而离婚参与者对非手术整容手术的平均接受度评分较高.年龄越高,整容手术的接受度越高(95%CI:1-15),而收入较高与接受度较低相关(95%CI:-14至-0.32)。较高的父母教育水平与手术和非手术整容手术的接受度较低相关(95%CI:-23至-3.5)。认为缺乏对整容手术的需求是不接受这些手术的最常见原因。而宗教信仰是第二个最常见的原因。结论非手术美容手术的接受度普遍高于美容手术。年龄,性别,婚姻状况,收入水平,家族影响,和以前的经验都在塑造这些态度方面发挥了重要作用。人们认为缺乏对程序和宗教信仰的需求是不接受整容手术的常见原因。
    Background and objective  Cosmetic surgery is a field that primarily focuses on the preservation, rebuilding, or improvement of the physical appearance of an individual through surgical and therapeutic methods. This specialization encompasses various interventions, both surgical, such as blepharoplasty, rhinoplasty, and breast augmentation, and non-surgical, including procedures such as chemical peeling, Botox injections, and dermal fillers. This study aims to assess the acceptance of cosmetic surgeries and non-surgical cosmetic procedures and the reasons for non-acceptance in a population from Jazan, Saudi Arabia. Methods This cross-sectional survey study was conducted in the general population of Jazan, Saudi Arabia, between July and August 2023. An online self-administered questionnaire was created using Google Forms and distributed through social media. The acceptance was measured using the Arabic translation of the Acceptance of Cosmetic Surgery Scale (ACSS). Results The mean cosmetic surgery acceptance score was 62.1 ± 25.9, whereas the mean non-surgical procedure acceptance score was 63.7 ± 24.5. Engaged and widowed participants had a higher mean acceptance score for cosmetic surgery, whereas divorced participants had a higher mean acceptance score for non-surgical cosmetic procedures. Higher age was associated with higher acceptance of cosmetic surgery (95% CI: 1-15), while having higher income was associated with lower acceptance (95% CI: -14 to -0.32). A higher level of parental education was associated with lower acceptance of surgical and non-surgical cosmetic procedures (95% CI: -23 to -3.5). The perceived lack of a need for cosmetic procedures was the most commonly cited reason for not accepting these procedures, while religious beliefs were the second most common reason. Conclusion Non-surgical cosmetic procedures generally had higher acceptance than cosmetic surgeries. Age, sex, marital status, income level, familial influence, and prior experience all played significant roles in shaping these attitudes. The perceived lack of a need for the procedures and religious beliefs were common reasons for not accepting cosmetic procedures.
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  • 文章类型: English Abstract
    Objective:This study aims to provide a comprehensive summary of the pathogenesis, screening modalities, treatment strategies, repair modalities and preliminary results associated with facial nerve tumors. Methods:A retrospective analysis was conducted on the clinical data of 12 patients with facial nerve tumors who were admitted to our department between May 2018 and February 2023. The study population consisted of 5 males and 7 females, with ages ranging from 35 to 90 years. Clinical symptoms observed in these patients included facial nerve palsy, hearing loss, tinnitus, headache, and otalgia, etc. The severity of facial nerve dysfunction was assessed using the House-Brackmann(H-B) facial nerve function classification, with 3 cases classified as grade Ⅰ, 4 cases as grade Ⅲ, 2 cases as grade Ⅳ, and 3 cases as grade Ⅴ. There was a total of 11 patients who presented with hearing loss. Among these patients, 7 cases were diagnosed with conductive hearing loss, 2 cases with sensorineural hearing loss, and 2 cases with mixed hearing loss. The selection of the observation or surgical route for tumor localization was based on clinical symptoms, facial nerve function grading, and imaging examination results including temporal bone CT and enhanced MRI. Specifically, the location of the tumor was selected for observation or the best surgical route: 2 cases were followed up for observation, 1 case underwent biopsy, and 9 cases underwent tumor resection(7 cases of trans-mastoid approach, 2 cases of combined parotid-mastoidal approach), concurrent repair of the facial nerve(4 cases of auricular nerve grafting, 3 cases of facial nerve diversion anastomosis, 2 cases of peroneal nerve grafting). (4 cases of auricular nerve graft, 3 cases of facial nerve diversion anastomosis and 2 cases of peroneal nerve grafting). Periodic postoperative evaluation of facial nerve function was conducted. Results:1-year follow-up was available. Intraoperatively, it was observed that 66.7%(6 out of 9) of the facial nerve tumors were present in multiple segments. Among these segments, the vertical segment had the highest proportion, accounting for 77.8%(7 out of 9), followed by the labyrinthine segment/geniculate ganglion with 66.7%(6 out of 9) and the horizontal segment with 55.6%(5 out of 9). Postoperative pathology confirmed 8 cases with nerve sheath meningioma, Ⅰ with seminal fibroma and 1 with hemangioma. Postoperative facial nerve function was graded as H-B grade I in one patient), grade Ⅲ in three, grade Ⅳ in four, grade Ⅴ in 2, and grade Ⅵ in 2 patients. The auditory outcomes following surgery are as follows: 8 individuals experienced postoperative hearing loss, while 2 individuals demonstrated postoperative hearing preservation. Conclusion:In the case of patients presenting with facial nerve palsy as their initial symptom, it is imperative to consider the potential presence of a facial nerve tumor. To determine the appropriate course of action, it is necessary to ascertain the size and location of the tumors through imaging examinations. This information will aid in the decision making process regarding whether surgical intervention is warranted, and so, the most suitable approach. Additionally, the choice of repair method during the operation should be guided by the extent of facial nerve defect.
    目的:总结面神经肿瘤发病特征、检查方式、治疗策略、修复方式及初步效果。 方法:回顾分析2018年5月至2023年2月收治的12例面神经肿瘤患者的临床资料,其中男5例,女7例;年龄35~90岁。临床症状包括面神经麻痹、听力下降、耳鸣、头痛、耳痛等,按House-Brackmann(H-B)面神经功能分级:Ⅰ级3例,Ⅲ级4例,Ⅳ级2例,Ⅴ级3例。听力下降患者11例:传导性聋7例,感音神经性聋2例,混合性聋2例。根据临床症状、面神经功能分级、影像学检查(颞骨CT、增强MRI)结果确定肿瘤所处位置选择观察或最佳手术径路:2例随访观察,1例行肿物活检术,9例切除肿瘤(经乳突入路7例、经腮腺乳突联合入路2例)并同期行修复面神经(耳大神经移植4例、面神经改道吻合3例、腓肠神经移植2例)。术后定期评估面神经功能。 结果:术后随访1年。术中可见66.7%(6/9)面神经肿瘤位于多个节段:垂直段占比最大77.8%(7/9),其次是迷路段/膝状神经节66.7%(6/9)和水平段55.6%(5/9)。病理报告:神经鞘膜瘤8例,神纤维瘤和血管瘤各1例。10例术后患者面神经功能:Ⅰ级1例,Ⅲ级1例,Ⅳ级4例,Ⅴ级2例,Ⅵ级2例。10例术后患者听力情况:8例术后听力下降,2例术后听力保留。 结论:对首发症状为面神经麻痹的患者应考虑面神经肿瘤可能;根据影像学检查明确肿瘤大小、位置选择是否手术及手术方式;术中根据面神经缺损长度选择修复方式。.
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  • 文章类型: Journal Article
    距骨和颈部的开放性骨折并不常见。以前有关深部感染率和手术要求的报道差异很大。这项研究的主要目的是报告孤立的开放性距骨和颈部骨折的深部感染的发生率,其次是手术总数(TSP)的发生率和数量,二次打捞程序(SSP),和非救助程序(NSP)。
    32例连续孤立的开放性距骨骨折患者的回顾性病例对照研究(22颈,10例)随访,平均39.2个月。
    5处(15.6%)骨折发生深部感染。与0%的颈部骨折相比,50%的开放性身体骨折被感染(P<0.001)。感染组(IG)和未感染骨折组(UG)在年龄上没有差异,性别,身体质量指数,烟草,糖尿病,血管疾病,开放性骨折类型,伤口位置,小时灌溉和清创,或确定的治疗。大多数(92.6%)的UG骨折使用开放伤口延伸的双切口。IG组中有更多的单一延伸方法(P=.04)。IG每位患者需要5.8TSP,而UG为2.1(P=.004)。所有(100%)的IG需要SSP,而UG的29.6%(P=.006)。与UG的40.7%(P=0.043)相比,所有(100%)IG需要NSP。在IG中,确定性手术后每位患者需要2.8NSP,而UG为1.18(P=.003)。其中1年后,IG中SSP的发生率仍然较高(P=0.016)。
    孤立的开放性距骨骨折后深部感染的发生率很高,并且在身体骨折中不成比例地发生。感染骨折需要近6次手术,和所有需要的SSP。
    四级,预后。
    UNASSIGNED: Open fractures of the talar body and neck are uncommon. Previous reports of associated deep infection rates and resulting surgical requirements vary widely. The primary objective of this study is to report the incidence of deep infections for isolated open talar body and neck fractures, and secondarily the incidence and number of total surgeries performed (TSP), secondary salvage procedures (SSPs), and nonsalvage procedures (NSPs).
    UNASSIGNED: Retrospective case-control study of 32 consecutive isolated open talus fracture patients (22 neck, 10 body) were followed for an average of 39.2 months.
    UNASSIGNED: Five (15.6%) fractures developed deep infections. Fifty percent of open body fractures became infected compared with 0% of neck fractures (P < .001). There was no difference between infected group (IG) and uninfected fracture group (UG) with respect to age, sex, body mass index, tobacco, diabetes, vascular disease, open fracture type, wound location, hours to irrigation and debridement, or definitive treatment. The majority (92.6%) of UG fractures used a dual incision with open wound extension. There were more single extensile approaches in the IG group (P = .04). The IG required 5.8 TSP per patient compared with 2.1 in the UG (P = .004). All (100%) of the IG required an SSP compared with 29.6% of the UG (P = .006). All (100%) of the IG required an NSP compared to 40.7% of the UG (P = .043). In the IG, 2.8 NSPs per patient were required after definitive surgery compared with 1.18 in the UG (P = .003). Of those followed 1 year, the incidence of SSP remained higher in the IG (P = .016).
    UNASSIGNED: The incidence of deep infection following isolated open talar fractures is high and occurs disproportionally in body fractures. Infected fractures required nearly 6 surgeries, and all required SSP.
    UNASSIGNED: Level IV, prognostic.
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  • 文章类型: Journal Article
    背景:对于接受手术治疗的血友病A(PwHA)患者使用因子(F)VIII抑制剂的患者,围绕埃米珠单抗预防和围手术期治疗的指南是有限的。IIIb多中心阶段,单臂STASEY研究评估了使用FVIII抑制剂的年龄≥12岁的PwHA患者使用emicizumab预防的安全性和耐受性.本分析评估研究期间的手术,相关的血友病药物,和术后出血(治疗和未治疗)。方法使用FVIII抑制剂的PwHA接受美珠单抗3.0mg/kg/周治疗4周,然后1.5毫克/公斤/周,直到2年。手术由治疗医生管理和记录。医生和参与者记录了出血和治疗。结果46名参与者进行了≥1次研究手术,37人接受了56次小手术,13人接受了22次重大手术。四名参与者接受了小型和大型手术。在18例(81.8%)和4例(18.2%)大手术中有/没有额外的止血药物,33.3%和25.0%与治疗后出血相关,分别。在24例(42.9%)和32例(57.1%)小手术中有/没有额外的止血药物,15.6%和25.0%与治疗后出血相关,分别。重组活化FVII是最常用的预防和出血治疗药物。没有血栓性微血管病(TMAs)。一个肥大的血块,被认为与emicizumab无关,发生在拔牙后。结论在这个具有高出血风险的挑战性人群中,在接受有/没有额外止血药物的emicizumab的PwHA中进行了主要手术.59.1%的大型手术后发生术后出血;53.8%得到治疗。没有因伴随的emicizumab和旁路剂而发生动脉/静脉血栓事件或TMA。试验注册本试验在ClinicalTrials.gov(NCT03191799)注册。
    Background  Guidelines surrounding emicizumab prophylaxis and perioperative treatment for people with hemophilia A (PwHA) with factor (F)VIII inhibitors undergoing surgeries are limited. The phase IIIb multicenter, single-arm STASEY study evaluated safety and tolerability of emicizumab prophylaxis in PwHA aged ≥12 years with FVIII inhibitors. This analysis assesses surgeries during study conduct, associated hemophilia medications, and postoperative bleeds (treated and untreated). Methods  PwHA with FVIII inhibitors received emicizumab 3.0 mg/kg/week for 4 weeks, then 1.5 mg/kg/week until 2 years. Surgeries were managed and documented by treating physicians. Bleeds and treatments were recorded by physicians and participants. Results  Forty-six participants had ≥1 on-study surgery, 37 underwent 56 minor surgeries, and 13 underwent 22 major surgeries. Four participants underwent both minor and major surgeries. Of 18 (81.8%) and 4 (18.2%) major surgeries managed with/without additional hemostatic medication, 33.3 and 25.0% were associated with a treated postoperative bleed, respectively. Of 24 (42.9%) and 32 (57.1%) minor surgeries managed with/without additional hemostatic medication, 15.6 and 25.0% were associated with a treated postoperative bleed, respectively. Recombinant activated FVII was the most common medication for prophylaxis and bleed treatment. There were no thrombotic microangiopathies (TMAs). One hypertrophic clot, considered unrelated to emicizumab, occurred following tooth extraction. Conclusion  In this challenging population with a high bleeding risk, major surgeries were performed in PwHA receiving emicizumab with/without additional hemostatic medication. Postoperative bleeds occurred following 59.1% of major surgeries; 53.8% were treated. No arterial/venous thrombotic events or TMAs occurred due to concomitant emicizumab and bypassing agents. Trial registration  This trial is registered at ClinicalTrials.gov (NCT03191799).
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  • 文章类型: Journal Article
    术中神经生理监测(IONM)涉及使用电生理技术在手术期间监测关键脑区域和通路的功能完整性以及识别和保留功能上可行的神经组织(映射)。多模态结合了各种神经生理学技术,以优化诊断效果并改善手术结果。本研究是一个案例系列,对使用多模式方法进行的五例神经监测的颅骨和脊髓肿瘤手术的神经生理学变化进行了全面和说明性的描述。对病例进行体感诱发电位(SSEP)监测,经颅运动诱发电位(TcMEP),以及自由运行和触发肌电图(fEMG和tEMG)。在研究的病例中没有发现假阴性结果,因为SSEP和TcMEP均无变化。术后无神经功能缺损.两例被确定为具有真阳性神经监测警报。在任何情况下都没有发现假阳性警报。使用SSEP的多模态监测,TcMEP,和EMG(fEMG和tEMG)在颅骨和脊柱肿瘤手术中可以提高性能,减少假阴性和假阳性结果。联合使用的神经监测方法可以提供有关术后神经系统结果的可靠信息。
    Intraoperative neurophysiological monitoring (IONM) involves monitoring the functional integrity of critical brain regions and pathways as well as identifying and preserving functionally viable neural tissues (mapping) during surgery using electrophysiological techniques. Multimodality combines various neurophysiological techniques to optimise diagnostic effectiveness and to improve the outcomes of the surgeries. The present study is a case series with comprehensive and illustrative descriptions of the neurophysiological changes in five neuromonitored cases of cranial and spinal cord tumour surgeries conducted with a multimodal approach. The cases were monitored with somatosensory evoked potentials (SSEP), transcranial motor evoked potentials (TcMEP), and both free run and triggered electromyography (fEMG and tEMG). No false negative outcomes were identified in the cases studied as there was an association of absence of change in SSEP and TcMEP both, with no neurological deficit postoperatively. Two cases were identified as having true positive neuromonitoring alerts. No false positive alerts were found in any case. Multimodal monitoring using SSEP, TcMEP, and EMG (fEMG and tEMG) in cranial and spinal tumour surgeries can improve performance with fewer false-negative and false-positive results. Neuromonitoring approaches used in combination can provide reliable information regarding postoperative neurological outcomes.
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  • 文章类型: Journal Article
    髋关节或膝关节严重软骨退化或导致脊柱畸形的椎骨塌陷的人可能会遭受背部的关节和神经性疼痛,患肢的废弃,限制行动。手术干预是迄今为止最广泛和最成功的解决方案。人们普遍认为,健康饮食和保持身体和精神活跃可能对肌肉骨骼疾病的发生具有预防作用,而相反,我们更确定在进行大型骨科手术后,健康饮食和运动疗法会带来好处。实际上,这些方面是增强手术后恢复的重要组成部分。然而,它们适用于医院环境,通常是依赖中心的,自患者出院结束以来,缺乏一级和三级预防功效。在领土一级缺乏倡议,以确保患者的骨科手术之旅的连续性,家庭过渡,健康持久的生活.专家小组主张整合促进健康饮食的中间生活方式诊所,身体活动,和睡眠卫生。在这个由专业人员指导的促进手术后恢复的设施中,患者可以在手术指征后和家庭出院前转诊。手术实际上是个人更渴望尽力治愈和保持健康的时刻,代表了一个时间点和机会,教育患者生活方式的改变不仅可以优化他们的手术恢复,还可以优化未来的长期健康状况。
    Individuals with severe cartilage degeneration of the hip or knee or collapsed vertebrae that cause spine deformities can suffer from joint and neuropathic pain in the back, disuse of the affected limb, and restriction of movements. Surgical intervention is the most widespread and successful solution to date. There is a general belief that eating healthy and staying physically and mentally active might have a preventive role against musculoskeletal disease occurrence, while instead, we are more certain of the benefits deriving from a healthy diet and exercise therapy after major orthopaedic procedures. These aspects are in fact vital components in enhanced recovery after surgery programmes. However, they are applied in hospital settings, are often centre-dependent, and lack primary and tertiary preventive efficacy since end once the patient is discharged. There is the lack of initiatives at the territorial level that ensure a continuum in the patient\'s journey towards orthopaedic surgery, home transition, and a healthy and long-lasting life. The expert panel advocates the integration of an intermediate lifestyle clinic that promotes healthy eating, physical activity, and sleep hygiene. In this facility directed by professionals in enhancing recovery after surgery, patients can be referred after the surgical indication and before home discharge. Surgery is in fact a moment when individuals are more curious to do their best to heal and stay healthy, representing a timepoint and opportunity for educating patients on how lifestyle changes may optimise not only their surgical recovery but also long-term future health state.
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  • 文章类型: Journal Article
    目的:肝胰胆(HPB)手术是最具挑战性和最复杂的手术之一。术中冰冻切片(IFS)诊断在管理决策中起着举足轻重的作用。缺乏评估IFS在HPB恶性肿瘤中的效用的综合大型队列研究。本研究旨在评估冰冻切片分析的准确性,并分析IFS对手术决策的差异和影响。
    方法:这是2009年至2021年HPB标本接受IFS的回顾性研究。将结果与永久性切片进行比较,以评估诊断准确性,敏感性和特异性。指示,分析了分歧和对手术管理的影响。
    结果:共评估了1008个标本:胆管边缘(279;27.7%),胆囊(203;20.1%),肝脏病变125例(12.4%),淋巴结(147;14.6%),胰腺边缘(120;11.9%)和沉积物(134;13.3%)。IFS被诊断为恶性肿瘤阴性(805;79.9%),异型增生阳性(8;0.8%),可疑为恶性肿瘤(6;0.6%),恶性肿瘤阳性(189;18.8%)。总体诊断准确率为98.4%,不一致率为1.6%。敏感性,特异性,阳性预测值和阴性预测值分别为94.7%,99.4%,分别为97.5%和98.6%。结果不一致的最重要原因是技术,其次是解释误差和抽样误差。
    结论:该研究表明IFS在大型HPB样本数据集中具有很高的诊断准确性(98.4%)。对适应症的全面分析,错误以及IFS诊断对后续HPB手术管理的影响。
    OBJECTIVE: Hepato-pancreato-biliary (HPB) surgeries are one of the most challenging and complex procedures. Intraoperative frozen section (IFS) diagnosis plays a pivotal role in management decisions. Comprehensive large cohort studies evaluating utility of IFS in HPB malignancies are lacking. This study aimed to evaluate the accuracy of frozen section analysis and to analyse discrepancies and impact of IFS on the surgical decisions.
    METHODS: This was a retrospective study of IFS received for the HPB specimens between years 2009 and 2021. The results were compared to the permanent sections to evaluate diagnostic accuracy, sensitivity and specificity. Indications, disagreements and impact on the surgical management were analysed.
    RESULTS: A total of 1008 specimens were evaluated: bile duct margin (279; 27.7%), gallbladder (203; 20.1%), liver lesions (125 cases; 12.4%), lymph nodes (147; 14.6%), pancreatic margin (120; 11.9%) and deposits (134; 13.3%). IFS were diagnosed as negative for malignancy (805; 79.9%), positive for dysplasia (8; 0.8%), suspicious for malignancy (6; 0.6%) and positive for malignancy (189; 18.8%). The overall diagnostic accuracy was 98.4%, and the discordant rate was 1.6%. The sensitivity, specificity, positive predictive value and negative predictive value were 94.7%, 99.4%, 97.5% and 98.6% respectively. The most important reason of discordant results was technical, followed by interpretational and sampling errors.
    CONCLUSIONS: The study demonstrates high diagnostic accuracy (98.4%) of IFS in a large dataset of HPB specimens. This comprehensive analysis apprises of the indications, errors and the impact of IFS diagnosis on subsequent HPB surgical management.
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