■特发性突发性感觉神经性耳聋的发病机制尚不清楚,在治疗方面没有取得实质性突破。因此,本研究通过内耳三维液体衰减倒置恢复(3D-FLAIR)磁共振成像(MRI),探讨特发性突发性感音神经性耳聋和听觉神经增强患者的临床特征和预后因素.
■我们回顾性分析了成年患者的临床资料,经历过突发性单侧耳聋并进入耳鼻喉科,山东省耳鼻喉科医院,2020年12月至2021年7月。患者分为听神经增强组和正常内耳组,根据3D-FLAIRMRI检查结果。性别差异,年龄,侧面,病程,潜在的疾病,头晕/眩晕,前庭功能,耳聋程度,听力分类,并对治疗效果进行分析。
■112例突发性特发性耳聋,内耳3D-FLAIRMRI显示听神经增强16.07%。两组间听力损失程度和类型差异有统计学意义(p<0.05)。异常率导致热量,前庭诱发的肌源性电位,在听觉神经增强组中,视频头脉冲测试更高。听神经强化患者的治愈率(11.1%)低于内耳MRI表现正常的患者(28.7%);差异无统计学意义。
■内耳的3D-FLAIRMRI扫描发现,突发性耳聋和听觉神经增强的患者出现了严重的听力损失,加重前庭功能损伤,治愈率明显下降。及时治疗,理想情况是在疾病发作后2周内,可以促进听力恢复。
UNASSIGNED: The pathogenesis of idiopathic
sudden sensorineural hearing loss remains unclear, and no substantial breakthroughs have been achieved in its treatment. Therefore, we conducted this study with the aim to investigate the clinical features and prognostic factors of patients with idiopathic
sudden sensorineural hearing loss and auditory nerve enhancement by using three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) magnetic resonance imaging (MRI) of the inner ear.
UNASSIGNED: We retrospectively analyzed the clinical data of adult patients, who experienced
sudden unilateral deafness and were admitted to the Department of Otolaryngology, Shandong Provincial ENT Hospital, between December 2020 and July 2021. Patients were divided into an auditory nerve enhancement group and a normal inner ear group, according to 3D-FLAIR MRI findings. Differences in sex, age, side, disease course, underlying diseases, dizziness/vertigo, vestibular function, degree of deafness, hearing classification, and treatment efficacy were analyzed.
UNASSIGNED: Of the 112 cases of
sudden idiopathic deafness, 16.07% exhibited enhancement of the auditory nerve on inner-ear 3D-FLAIR MRI. Statistically significant differences in the degree and type of hearing loss were detected between the two groups (p < 0.05). The rates of abnormal results in the caloric, vestibular-evoked myogenic potential, and video head impulse tests were higher in the auditory nerve enhancement group. The cure rate (11.1%) in patients with auditory nerve enhancement was lower than that in patients with normal inner ear MRI findings (28.7%); however, the difference was not statistically significant.
UNASSIGNED: Findings from 3D-FLAIR MRI scans of the inner ear indicated that patients with
sudden deafness and auditory nerve enhancement experienced severe hearing loss, aggravated vestibular function injury, and a significantly decreased cure rate. Prompt treatment, ideally within 2 weeks of disease onset, can facilitate hearing recovery.