我们介绍了一例60多岁的男性,有α-gal综合征(AGS)病史,他反复出现急性结肠假性梗阻,也被称为奥格尔维综合征,并接受了结肠扩张的限制性症状的手术治疗,便秘,和腹痛。手术前,他在食用牛肉后多次住院,并被诊断出患有Ogilvie综合征,需要直肠管放置的结肠镜检查以解决症状。他后来接受了机器人结肠次全切除术和回肠结肠吻合术。随访显示便秘和腹胀症状改善。这个案例突出表明,AGS可能导致严重的表现,如复发性Ogilvie综合征。由于AGS的患病率越来越高,病程数据有限,需要进一步的研究来确定症状表现和手术在治疗中的潜在效用.
We present a case of a male in his 60s with a history of alpha-gal syndrome (AGS) who presented with recurrent acute colonic pseudo-obstruction, also known as Ogilvie syndrome, and underwent surgical treatment for life-limiting symptoms of colonic distention, constipation, and abdominal pain. Prior to surgery, he was hospitalized multiple times after beef consumption and was diagnosed with Ogilvie syndrome, requiring a colonoscopy with rectal tube placement for symptom resolution. He later underwent a robotic subtotal colectomy with ileocolic anastomosis. Follow-up visits showed improvement in symptoms of constipation and abdominal distention. This case highlights that AGS may lead to severe manifestations, such as recurrent Ogilvie syndrome. Due to the increasing prevalence of AGS and limited data on disease course, further research is needed to determine symptom manifestations and the potential utility of surgery in management.