背景:我们先前的研究表明,在单次视频EEG监测(VEEG)期间,同一患者的功能性癫痫发作(FS)是一致的。这项研究旨在检查即使在几年后,FS是否在VEEG会议上保持一致。
方法:该研究使用五个标准评估了不同VEEG会话中FS的一致性:FS类型,涉及的主要解剖区域(具体来说,癫痫发作期间受影响最大的身体部位),其他涉及的解剖区域,运动的频率,和FS的持续时间。一致性级别被归类为低(一个一致轴),中等(两个一致的轴),和高(三个或更多一致的轴)。
结果:14例患者被纳入最终分析。监测之间的平均时间为3.8±2.5年(0.5-8年)。14名患者中有13名,第一次和第二次监测事件被归类为相同的FS类别.在12例运动性FS患者中,有9例涉及的主要解剖区域具有一致性。在12名运动性FS患者中,有9名两个疗程中涉及的其他解剖区域一致.在大多数患者中,疗程之间的平均FS持续时间不一致。10例患者分类一致性高,一名中度一致性的患者,两名一致性低的患者,一个病人,事件被归类为不一致.
结论:我们的结果表明,即使几年后,单个患者的FS也趋于保持一致,一致性程度和VEEG会议之间的时间之间可能没有相关性。这些发现对于支持FS的概念是一个一致的现象具有重要意义。此外,他们可能为未来的研究提供潜在的途径,以阐明FS的起源。后续研究对于验证和扩展这些初步观察至关重要。
Our previous study showed that functional seizures (FS) are consistent in the same patient during a single video EEG monitoring (VEEG). This study aimed to check whether FS remains consistent across VEEG sessions even after several years.
The study evaluated the consistency of FS across different VEEG sessions using five criteria: FS type, the main anatomical region involved (specifically, the body part most affected during the seizure), other involved anatomical regions, frequency of movements, and duration of FS. Consistency levels were categorized as low (one consistent axis), moderate (two consistent axes), and high (three or more consistent axes).
Fourteen patients were included in the final analysis. The mean time between monitoring was 3.8 ± 2.5 years (0.5-8 year). In 13 of 14 patients, the first and second monitoring events were classified into the same FS category. There was consistency in the main anatomical region involved in 9 out of 12 patients with motor FS. In 9 out of 12 patients with motor FS, the other anatomical regions involved were consistent in both sessions. The mean duration of the FS between sessions was inconsistent in most of the patients. Ten patients were classified with high consistency, one patient with moderate consistency, two patients with low consistency, and in one patient, the events were classified as inconsistent.
Our results show that FS tends to remain consistent in a single patient even after several years, and there is probably no correlation between the degree of consistency and the time between VEEG sessions. These findings have implications for supporting the concept of FS as a consistent phenomenon. Additionally, they may suggest potential avenues for future research to elucidate the origins of FS. Subsequent studies are essential to validate and expand upon these preliminary observations.