■紧急发作疾病,如癫痫持续状态和集束性癫痫发作不可能自发停止,而长时间的癫痫发作活动逐渐变得对治疗更具抵抗力。犬癫痫患者早期使用抢救药物,特别是苯二氮卓类药物,在癫痫发作时,主人可以挽救生命和保护大脑。在医院环境中评估使用救援药物的狗的临床研究存在,然而,迄今为止,尚未评估所有者的观点。
■评估主人在家中对癫痫发作紧急情况的狗使用救护药物的情况。
■基于对患有紧急癫痫症的狗主人的在线调查的观察性研究。
■问卷由1,563名狗主人回答,其中761人提供了适合分析的完整和准确的答案。其中,71%服用地西泮,19%咪达唑仑,6%左乙拉西坦,3%劳拉西泮,和4%以上的救援或其他药物。总的来说,根据所有者的观点,鼻内咪达唑仑和直肠地西泮的成功率分别为97%和63%,分别。所有者报告鼻内咪达唑仑和直肠地西泮给药的依从性为95%和66%,分别。
■尽管直肠地西泮是本次调查人群中最常用的救护药物,鼻内咪达唑仑被认为是一个更好的选择,关于有效性,停止癫痫发作和所有者遵守的时间。
UNASSIGNED: Emergency seizure disorders such as status epilepticus and cluster seizures are unlikely to cease spontaneously while prolonged seizure activity become progressively more resistant to treatment. Early administration of rescue medication in canine epileptic patients, in particular benzodiazepines, at seizure onset by the owners can be life-saving and brain protecting. Clinical studies in dogs evaluating the use of rescue medication in hospital environment exist, however, the owner perspective has not been assessed to date.
UNASSIGNED: To evaluate the use of rescue medication in dogs with seizure emergencies by the owner at home.
UNASSIGNED: Observational study based on online surveys of owners of dogs with emergency seizure disorders.
UNASSIGNED: The questionnaire was answered by 1,563 dog owners, of which 761 provided complete and accurate answers suitable for analysis. Of these, 71% administered diazepam, 19% midazolam, 6% levetiracetam, 3% lorazepam, and 4% more than one rescue or other medication. Overall, the success rates based on owners\' perspective for intranasal midazolam and rectal diazepam were 97 and 63%, respectively. Owners reported a compliance level of 95 and 66% for intranasal midazolam and rectal diazepam administration, respectively.
UNASSIGNED: Even though rectal diazepam was the most used rescue medication in this survey population, intranasal midazolam was perceived by the owners as a better option regarding effectiveness, time to seizure cessation and owner compliance.