确定整个大脑结构与个体差异之间的关系对于延长健康的预期寿命很重要,会受到脑萎缩的影响。人们逐渐认识到整个大脑结构不仅与年龄相关,而且与个体差异相关,比如生活质量,一般智力,和生活方式。然而,人们很少关注整个大脑结构和个人特质之间的关系。我们在这里专注于一个个人特质,即精神成长,并使用两种神经成像方法检查了其与整个大脑结构的关系,即灰质脑保健商(GM-BHQ),衡量转基因体积,和分数各向异性脑保健商(FA-BHQ),白质(WM)完整性的量度,在229名健康参与者中(53名女性,176男)。结果表明,GM-BHQ与精神成长之间没有显着关系,但在控制年龄后,FA-BHQ与精神成长之间存在显著正相关,性别,与体重指数(BMI)进行偏相关分析。此外,多元回归分析显示,在控制身体特征后,FA-BHQ与精神成长之间存在显著正相关,比如年龄,性别,BMI,以及使用健康促进生活方式简介收集的与生活方式相关的其他变量。这些结果支持了整个WM大脑结构与精神成长之间存在关系的观点。需要进一步的研究来阐明整个WM大脑结构与精神成长之间的因果关系,并采取一些干预措施来改善精神成长。这些研究将有助于从个人特质的新角度延长健康预期寿命。
Determining the relationship between the entire brain structure and individual differences is important in extending healthy life expectancy, which can be affected by brain atrophy. The entire brain structure has been gradually known to be correlated not only with age but also with individual differences, such as quality of life, general intelligence, and lifestyle. However, little attention has been paid to the relationship between the entire brain structure and personal traits. We herein focused on one personal trait, namely spiritual growth, and examined its relationship with the entire brain structure using two neuroimaging-derived measures, namely the gray matter Brain Healthcare Quotient (GM-BHQ), a measure of GM volume, and the fractional anisotropy Brain Healthcare Quotient (FA-BHQ), a measure of white matter (WM) integrity, in 229 healthy participants (53 female, 176 male). The results indicated no significant relationship between the GM-BHQ and spiritual growth, but there was a significant positive correlation between the FA-BHQ and spiritual growth after controlling for age, sex, and body mass index (BMI) with partial correlation analysis. Furthermore, multiple regression analysis revealed a significant positive correlation between the FA-BHQ and spiritual growth after controlling for physical characteristics, such as age, sex, and BMI, as well as other variables related to lifestyle that were collected using the Health-Promoting Lifestyle Profile. These results support the idea that there is a relationship between the entire WM brain structure and spiritual growth. Further studies are required to clarify the causal relationship between the entire WM brain structure and spiritual growth with some interventions to improve spiritual growth. Such studies will help extend healthy life expectancy from a new perspective of personal trait.