■本研究旨在探讨双侧先天性白内障(CC)患者术后近视移位及其与视力康复的关系。
■在6岁之前接受白内障摘除和初次人工晶状体植入的双侧CC患者被纳入研究,并根据手术年龄(<2、2-3、3-4、4-5和5-6岁)分为5组。术后近视移位率,球形当量(SE),测量和分析最佳矫正视力(BCVA)。
■共纳入234名患者的1,137项屈光测量,平均随访34个月。5组各次随访的术后平均SE均线性拟合,平均R2=0.93±0.03,表现为SE随年龄的下降趋势(线性回归)。在随访4年的患者中,在五个年龄组(从年轻人到老年人)中,平均术后近视移位率为每年0.84、0.81、0.68、0.24和0.28屈光度(D/y),分别。手术年龄<2岁的患者在4年访视时的BCVA为0.26(LogMAR),术后平均近视移位率为0.84D/y。对于手术年龄为2-6岁的患者,术后近视移位率较高的患者在4年访视时BCVA较差(r=0.974,p=0.026,Pearson相关性检验).
■对2岁之前的患者进行白内障手术,并降低手术年龄为2-6岁的患者的术后近视移位率,可能有利于视力康复。
UNASSIGNED: This study aimed to explore the postoperative myopic shift and its relationship to visual acuity rehabilitation in patients with bilateral congenital cataracts (CCs).
UNASSIGNED: Bilateral CC patients who underwent cataract extraction and primary intraocular lens implantations before 6 years old were included and divided into five groups according to surgical ages (<2, 2-3, 3-4, 4-5, and 5-6 years). The postoperative myopic shift rates, spherical equivalents (SEs), and the best corrected visual acuity (BCVA) were measured and analyzed.
UNASSIGNED: A total of 1,137 refractive measurements from 234 patients were included, with a mean follow-up period of 34 months. The postoperative mean SEs at each follow-up in the five groups were linearly fitted with a mean R2 = 0.93 ± 0.03, which showed a downtrend of SE with age (linear regression). Among patients with a follow-up of 4 years, the mean postoperative myopic shift rate was 0.84, 0.81, 0.68, 0.24, and 0.28 diopters per year (D/y) in the five age groups (from young to old), respectively. The BCVA of those with a surgical age of <2 years at the 4-year visit was 0.26 (LogMAR), and the mean postoperative myopic shift rate was 0.84 D/y. For patients with a surgical age of 2-6 years, a poorer BCVA at the 4-year visit was found in those with higher postoperative myopic shift rates (r = 0.974, p = 0.026, Pearson\'s correlation test).
UNASSIGNED: Performing cataract surgery for patients before 2 years old and decreasing the postoperative myopic shift rates for those with a surgical age of 2-6 years may benefit visual acuity rehabilitation.