small bowel disorders

  • 文章类型: Journal Article
    背景非侵入性成像模式的主要发展,与传统的计算机断层扫描(CT)和胶囊内窥镜检查相比,计算机断层成像(CTE)具有许多优势.通过利用多探测器计算机断层扫描(MDCT)技术,CTE加快了对小肠疾病的评估,特别是在那些无法通过传统内窥镜检查的部分。本研究的主要目标是全面评估CTE对一系列小肠疾病的诊断准确性。方法论在这次调查中,这是一项前瞻性观察研究,40名患者,25男15女,怀疑小肠疾病和年龄范围从10到70接受CTE。为了评估诊断的准确性,临床症状的组合,成像数据,和组织病理学/超声检查结果进行了评估。在整个研究过程中,纳入了伦理问题和统计分析,以保证有效性和遵守伦理规范。结果CTE最常见的表现是肠管增厚和粘膜过度增强,在25例(62.5%)和20例(50%)患者中观察到,分别。大多数患者(65%)在III级中表现出回肠和空肠环充分扩张。在35%的患者中,观察到回肠和空肠环的II级扩张性。结论在准确检测小肠疾病时,CTE优越。它评估肠外,壁画,和具有疗效的腔内疾病,特别是在难以到达的地方。它对于指导临床决策至关重要,因为它有能力在内窥镜检查之前评估疾病活动并查看后果。
    Background A major development in noninvasive imaging modalities, computed tomographic enterography (CTE) has a number of benefits over conventional computed tomography (CT) and capsule endoscopy. Through the utilization of multidetector computed tomography (MDCT) technology, CTE expedites the assessment of small bowel diseases, especially in those segments that are not accessible through traditional endoscopy. This study\'s main goal is to thoroughly evaluate CTE\'s diagnostic accuracy for a range of small intestinal conditions. Methodology In this investigation, which is a prospective observational study, 40 patients, 25 men and 15 women, with suspected small intestinal disorders and ages ranging from 10 to 70 underwent CTE. To evaluate diagnosis accuracy, a combination of clinical symptoms, imaging data, and histopathological/ultrasonography findings were evaluated. Throughout the research procedure, ethical issues and statistical analysis were incorporated to guarantee validity and adherence to ethical norms. Results The most frequent findings on CTE were bowel thickening and mucosal hyperenhancement, which were seen in 25 (62.5%) and 20 (50%) of the patients, respectively. The majority of patients (65%) exhibited both the ileal and jejunal loops to be adequately distended in grade III. In 35% of the patients, grade II distensibility of the ileal and jejunal loops was seen. Conclusion When it comes to accurately detecting small intestinal disorders, CTE is superior. It evaluates extraintestinal, mural, and intraluminal diseases with efficacy, particularly in places that are difficult to reach. It is essential for directing clinical decisions because of its capacity to assess disease activity prior to endoscopy and see consequences.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目的:息肉综合征如Peutz-Jeghers(PJ)和家族性腺瘤性息肉病(FAP)与小肠息肉的生长有关;PJ的风险约为60-90%,FAP的风险约为40-70%。这项研究的主要目的是评估设备辅助肠镜检查(DAE)在检测和治疗小肠息肉以降低手术风险方面的功效。次要目的是研究并发症和死亡率。
    方法:我们通过分析结构化数据库进行了一项回顾性队列研究。在2006年9月至2019年10月之间,我们观察并随访了42例息肉病综合征患者;他们接受了设备辅助肠镜检查,其中3例在检查后被排除在择期手术之外。进行内窥镜检查是为了诊断和治疗目的。
    结果:对39例患者进行了评估,平均随访时间为6.7年(±SD2.7),79.5%为女性,平均年龄为43.8岁(±SD15.02),进行了68次肠镜检查,切除了64个息肉样病变。一次手术肠镜检查后出血,6例PJ患者和5例FAP患者需要进行后续手术.PJ患者的手术指征是存在大息肉(3例)和3例肠套叠,其中一个病人在回肠近端有息肉,范围不可达。1例PJ患者在随访期间死于胰腺癌。FAP患者的手术指征是存在四个大息肉,高度异型增生和一个壶腹肿瘤复发。
    结论:在PJ患者中,小肠息肉的内镜治疗是安全的。在后续期间,内镜治疗成功的患者不需要手术.在接受DAE治疗的FAP患者中,没有人患上癌症。
    OBJECTIVE: Polyposis syndromes such as Peutz-Jeghers (PJ) and familial adenomatous polyposis (FAP) are associated with the growth of small bowel polyps; the risk is approximately 60-90% for PJ and 40-70% for FAP. The primary aim of this study was to evaluate the efficacy of device-assisted enteroscopy (DAE) in the detection and treatment of small bowel polyps to reduce the risk of surgery. The secondary objective was to study complications and mortality.
    METHODS: We conducted a retrospective cohort study by analyzing a structured database. Between September 2006 and October 2019, we observed and followed 42 consecutive patients with polyposis syndromes; they underwent device-assisted enteroscopy and three were excluded from elective surgery after the exam. The endoscopic exams were performed for diagnostic and therapeutic purposes.
    RESULTS: Thirty-nine patients were evaluated with a mean follow up of 6.7 years (±SD 2.7), 79.5% were female with a mean age of 43.8 years (±SD 15.02), and 68 enteroscopies were performed with the removal of 64 polypoid lesions. One bleeding episode occurred after operative enteroscopy, and the need for subsequent surgery occurred in six patients with PJ and in five patients with FAP. The surgical indications in PJ patients were the presence of large polyps (three patients) and three cases of intussusception, one of which was a patient with a polyp in the proximal ileum, not reachable with the scope. One patient with PJ died from pancreatic cancer during follow up. The surgical indications in patients with FAP were the presence of four large polyps with high-grade dysplasia and one ampullary neoplasia recurrence.
    CONCLUSIONS: In PJ patients, the endoscopic treatment of small bowel polyps was safe. During the follow-up period, the patients with successful endoscopic treatment did not need surgery. In FAP patients treated with DAE, none developed cancer.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    背景:设备辅助小肠镜检查是一种用于评估成人和儿童小肠的新内镜技术。儿科人群的数据有限。这篇综述旨在确定儿童肠镜检查的诊断和治疗益处。
    方法:我们分析了关于装置辅助肠镜检查的儿科文献,重点是适应症,技术方面和并发症,注意可能适用于儿科人群的成人出版物。
    结果:不明原因的消化道出血,克罗恩病和小肠息肉是儿童肠镜检查的主要指征。设备辅助肠镜检查对主要儿科适应症具有很高的诊断率,但在诊断工作中应事先使用MR小肠造影和胶囊内窥镜检查,以更好地确定小肠镜检查的候选人,并提高其诊断和治疗效果.主要并发症很少见,主要与治疗程序有关。
    结论:尽管儿科人群的数据有限,装置辅助肠镜检查是一种有用且安全的儿童内镜技术.它的使用,结合MR小肠造影和胶囊内窥镜检查,允许识别和治疗许多小肠儿科疾病,并发症风险低。
    BACKGROUND: Device-assisted enteroscopy is a new endoscopic technique for the evaluation of small bowel in adults and children. Data in pediatric population are limited. This review aims to identify diagnostic and therapeutic benefits of enteroscopy in children.
    METHODS: We have analysed paediatric literature on device-assisted enteroscopy focusing on indications, technical aspects and complications, with attention given to adult publications that may be applicable to the paediatric population.
    RESULTS: Obscure gastrointestinal bleeding, Crohn\'s disease and small bowel polyps are the main indications of enteroscopy in children. Device-assisted enteroscopy has high diagnostic yield for the main paediatric indications, but MR-enterography and capsule endoscopy should be used beforehand in diagnostic work-up to better identify candidates for enteroscopy and to improve its diagnostic and therapeutic yield. Major complications are rare and mostly related to therapeutic procedures.
    CONCLUSIONS: Despite limited data in the paediatric population, device-assisted enteroscopy represents a useful and safe endoscopic technique in children. Its use, combined with MR-enterography and capsule endoscopy, allows identification and treatment of many of the small bowel paediatric diseases with a low risk of complications.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    Small-bowel disorders remain a diagnostic and therapeutic challenge due to intestinal length. Their management was revolutionized by the emergence of deep enteroscopy. In comparison with video capsule endoscopy, deep enteroscopy allows diagnostic and therapeutic interventions. Spiral enteroscopy (Spirus Medical Endo-Ease Overtube) achieves progression by gentle push and manual clockwise rotation inducing pleating of the small bowel on the endoscope. It has the advantage of shorter examination time and more stability during withdrawal but requires two operators. The Novel Motorized Spiral Enteroscope (Olympus Corp.) incorporates a user-controlled motor contained in the handle of the endoscope. This would offer the possibility to accelerate the procedure, facilitate insertion, and simplify the technique with a single operator.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

公众号