slipped capital femoral epiphysis

滑脱的股骨骨 phy
  • 文章类型: Journal Article
    背景:股骨干骨水泥滑脱是一种常见的小儿髋关节疾病。最近的研究表明,脊柱的矢状轮廓可能会影响股骨近端生长板的滑移,一个没有广泛探索的方面。本研究利用有限元分析来研究各种脊柱骨盆排列如何影响剪切应力和生长板滑移。
    方法:从健康成年男性腰椎的CT扫描中建立了有限元模型,骨盆,和股骨。通过重新定向对模型进行各种矢状对齐。模拟两腿姿势,单腿站立,步行脚跟罢工,上升楼梯脚跟罢工,并进行了下楼梯的脚跟罢工。测量的参数包括髋关节接触面积,压力,和最大生长板Tresca(剪切)应力。
    结果:骨盆后倾斜病例显示,除了两腿站立外,与骨盆前倾斜变体相比,骨盆后倾斜病例显示更大的剪切应力。与前倾斜骨盆相比,两腿站立导致后倾斜骨盆变体髋关节接触和生长板Tresca应力降低,然而,骨盆后倾斜和高骨盆发生率的组合表明生长板上有较大的剪切应力。与骨盆前倾斜相比,一条腿站立和愈合撞击导致骨盆后倾斜变体中生长板上的剪切应力更高。后骨盆倾斜和高骨盆发生率的组合导致最大的剪切。
    结论:我们的研究结果表明,骨盆后倾斜和高骨盆发生率可能导致生长板处的剪切应力增加。在这些排列的患者中进行的活动可能会导致生物力学负荷剪切生长板,有可能导致滑倒。
    BACKGROUND: Slipped capital femoral epiphysis is a prevalent pediatric hip disorder. Recent studies suggest the spine\'s sagittal profile may influence the proximal femoral growth plate\'s slippage, an aspect not extensively explored. This study utilizes finite element analysis to investigate how various spinopelvic alignments affect shear stress and growth plate slip.
    METHODS: A finite element model was developed from CT scans of a healthy adult male lumbar spine, pelvis, and femurs. The model was subjected to various sagittal alignments through reorientation. Simulations of two-leg stance, one-leg stance, walking heel strike, ascending stairs heel strike, and descending stairs heel strike were conducted. Parameters measured included hip joint contact area, stress, and maximum growth plate Tresca (shear) stress.
    RESULTS: Posterior pelvic tilt cases indicated larger shear stresses compared to the anterior pelvic tilt variants except in two leg stance. Two leg stance resulted in decreases in the posterior tilted pelvi variants hip contact and growth plate Tresca stress compared to anterior tilted pelvi, however a combination of posterior pelvic tilt and high pelvic incidence indicated larger shear stresses on the growth plate. One leg stance and heal strike resulted in higher shear stress on the growth plate in posterior pelvic tilt variants compared to anterior pelvic tilt, with a combination of posterior pelvic tilt and high pelvic incidence resulting in the largest shear.
    CONCLUSIONS: Our findings suggest that posterior pelvic tilt and high pelvic incidence may lead to increased shear stress at the growth plate. Activities performed in patients with these alignments may predispose to biomechanical loading that shears the growth plate, potentially leading to slip.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    我们报告了一例滑脱的股骨骨epi(SCFE),泛FGFRTKI抑制剂的目标骨骼毒性,erdafitinib.一个13岁的男孩被诊断患有视路/下丘脑神经胶质瘤,有颅内压升高和阻塞性脑积水的迹象,需要放置脑室-腹膜(VP)分流术。肿瘤的测序显示FGFR1-酪氨酸激酶结构域内部串联重复(FGFR1-KD-ITD)。他发展为下丘脑肥胖,体重迅速增加,BMI>30。厄达非替尼治疗12周时,他出现了持续的膝盖疼痛。右侧髋部X线示SCFE。Erdafitinib被停用,他接受了右髋关节的手术固定.erdafitinib停药时的MRI显示肿瘤大小减少了30%,在6个月的随访中保持稳定。我们的经验和文献综述表明,使用pan-FGFRTKIs治疗的儿科患者应定期监测骨骼副作用。
    We report a case of slipped capital femoral epiphysis (SCFE), an on target skeletal toxicity of a pan-FGFR TKI inhibitor, erdafitinib. A 13-year-old boy was diagnosed to have an optic pathway/hypothalamic glioma with signs of increased intracranial pressure and obstructive hydrocephalus requiring placement of ventriculo-peritoneal (VP) shunt. Sequencing of the tumor showed FGFR1-tyrosine kinase domain internal tandem duplication (FGFR1-KD-ITD). He developed hypothalamic obesity with rapid weight gain and BMI >30. At 12 weeks of treatment with erdafitinib, he developed persistent knee pain. X-ray of the right hip showed SCFE. Erdafitinib was discontinued, and he underwent surgical pinning of the right hip. MRI at discontinuation of erdafitinib showed a 30% decrease in the size of the tumor, which has remained stable at 6 months follow-up. Our experience and literature review suggest that pediatric patients who are treated with pan-FGFR TKIs should be regularly monitored for skeletal side effects.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:滑脱的股骨骨epi(SCFE)是婴儿期和青春期最常见的髋关节疾病。我们的研究旨在分析经手术治疗的单侧SCFE儿童的静态足底压力。
    方法:通过PoData足底压力分析在三种不同情况下(睁眼,闭上眼睛,和头部后退)。
    结果:在所有三种测试条件下,与受影响的肢体相比,未受影响的肢体上的总足负荷显着增加(p<0.05)。在评估测试条件之间的差异时,右脚和左脚载荷没有显着差异,或者重量分布的三个部位,除了右第五meta头(与睁眼相比,闭眼状态下的负荷较低,p=0.0068),左第五跖骨头(与睁眼相比,头部后屈时负荷增加,p=0.0209),和左脚跟(与睁眼相比,头部后屈时负荷较低,p=0.0293)。
    结论:即使手术成功,足部负荷的差异会影响不同条件下的姿势静态活动(自然睁眼,闭着眼睛,或头部向后弯曲的姿势)。
    BACKGROUND: Slipped capital femoral epiphysis (SCFE) is the most common hip disease during infancy and adolescence. Our study aimed to analyze static plantar pressure in children with surgically treated unilateral SCFE.
    METHODS: Twenty-two children with right SCFE with in situ fixation with one percutaneous screw were assessed by PoData plantar pressure analysis under three different conditions (open eyes, eyes closed, and head retroflexed).
    RESULTS: The total foot loading was significantly higher on the unaffected limb compared with the affected one for all the three testing conditions (p < 0.05). When assessing the differences between testing conditions, there were no significant differences for the right and left foot loadings, or for the three sites of weight distribution, except for the right fifth metatarsal head (lower loading in eyes-closed condition in comparison to eyes open, p = 0.0068), left fifth metatarsal head (increased loading in head-retroflexed condition in comparison to eyes open, p = 0.0209), and left heel (lower loading in head-retroflexed condition in comparison to eyes open, p = 0.0293).
    CONCLUSIONS: Even after a successful surgical procedure, differences in foot loading can impact the postural static activities in different conditions (natural eyes-open, eyes-closed, or head-retroflexed posture).
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    滑脱股骨骨phy(SCFE)是青少年股骨近端的常见现象,病因不清楚。男孩比女孩更常见,似乎确实有一些种族倾向,体重,和年龄(Lehmann等人,2006年[7])。
    方法:我们报道了一个13岁的男孩,在左股骨粗隆下骨折后出现单侧SCFE,在SCFE前6个月用刀片板固定。SCFE由两个空心螺钉固定。我们旨在讨论用于股骨近端骨折的手术技术与SCFE延迟发作之间的可能联系。
    股骨粗隆下骨折治疗后的股骨骨epi(SCFE)滑脱可能是由于骨折治疗不足引起的。骨科医生应该意识到这种并发症,以便他们能够及时识别这种并发症并紧急治疗(Chinoy等人。,2020)。
    结论:股骨粗隆下骨折治疗后股骨骨epi滑脱(SCFE)是非常罕见的情况,可以通过使用适当的骨接合材料适当地复位和固定骨折来预防。
    UNASSIGNED: Slipped capital femoral epiphysis (SCFE) is a common phenomenon of the proximal femur in adolescents with an unclear etiology. It is more common in boys than girls and there does seem to be some predilection to race, weight, and age (Lehmann et al., 2006 [7]).
    METHODS: We reported a 13-year-old boy who presented with unilateral SCFE following subtrochanteric left femur fracture, which was fixed by blade plate 6 monthes before the SCFE. The SCFE fixed by two cannulated screw. We aim to discuss the possible link between the surgical technique used for proximal femur fractures and the delayed onset of SCFE.
    UNASSIGNED: Slipped capital femoral epiphysis (SCFE) after treatment of subtrochanteric fracture can be caused by inadequate treatment of the fracture. Orthopedic surgeons should be aware of this complication so that they can promptly recognize this complication and treat it urgently (Chinoy et al., 2020).
    CONCLUSIONS: Slipped capital femoral epiphysis (SCFE) after treatment of subtrochanteric fracture is a very rare condition, that it can be prevented by proper reduction and fixation of the fracture using appropriate osteosynthesis material.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    滑脱性股骨骨phy(SCFE)是一种常见的儿科髋关节疾病,有骨关节炎和撞击畸形的风险,和3D模型可用于患者特异性分析。因此,研究了磁共振成像(MRI)骨骼分割以及使用基于MRI的3D模型进行3D打印和3DROM模拟的可行性。
    进行了一项涉及22例SCFE症状患者(22髋)的回顾性研究。所有患者均接受术前髋关节MR和骨盆冠状高分辨率图像(T1图像)。切片厚度为0.8-1.2mm。平均年龄为12±2岁(59%为男性患者)。所有患者均行手术治疗。进行了基于MRI的半自动骨分割,并进行了手动校正和3D打印塑料3D模型。对虚拟3D模型进行了测试,以对具有膝盖图像的患者进行计算机辅助3DROM模拟,并将其与无症状的单侧SCFE的对侧臀部进行了比较(15髋,对照组)。
    基于MRI的骨骼分割是可行的(所有患者,100%,在4.5小时内,平均272±52分钟)。三维打印塑料3D模型是可行的(所有患者,100%),并且被治疗外科医生认为对重度和中度SCFE的畸形分析有帮助。三维ROM模拟显示(p<0.001)在90°屈曲(-14±21°)中屈曲(48±40°)和IR显着降低(p<0.001),IRF-90°)用于重度SCFE患者的MRI与对照组相比(122±9°和36±11°)。滑移角从术前54±15°改善至术后4±2°(p<0.001)。
    基于MRI的3D模型对于SCFE患者是可行的。三维模型可用于严重SCFE患者的术前3D打印和畸形分析以及ROM模拟。这可以帮助患者进行特定的诊断,治疗决定,和术前计划。基于MRI的3D模型是无辐射的,并且在未来可以被用于代替基于CT的3D模型。
    UNASSIGNED: Slipped capital femoral epiphyses (SCFE) is a common pediatric hip disease with the risk of osteoarthritis and impingement deformities, and 3D models could be useful for patient-specific analysis. Therefore, magnetic resonance imaging (MRI) bone segmentation and feasibility of 3D printing and of 3D ROM simulation using MRI-based 3D models were investigated.
    UNASSIGNED: A retrospective study involving 22 symptomatic patients (22 hips) with SCFE was performed. All patients underwent preoperative hip MR with pelvic coronal high-resolution images (T1 images). Slice thickness was 0.8-1.2 mm. Mean age was 12 ± 2 years (59% male patients). All patients underwent surgical treatment. Semi-automatic MRI-based bone segmentation with manual corrections and 3D printing of plastic 3D models was performed. Virtual 3D models were tested for computer-assisted 3D ROM simulation of patients with knee images and were compared to asymptomatic contralateral hips with unilateral SCFE (15 hips, control group).
    UNASSIGNED: MRI-based bone segmentation was feasible (all patients, 100%, in 4.5 h, mean 272 ± 52 min). Three-dimensional printing of plastic 3D models was feasible (all patients, 100%) and was considered helpful for deformity analysis by the treating surgeons for severe and moderate SCFE. Three-dimensional ROM simulation showed significantly (p < 0.001) decreased flexion (48 ± 40°) and IR in 90° of flexion (-14 ± 21°, IRF-90°) for severe SCFE patients with MRI compared to control group (122 ± 9° and 36 ± 11°). Slip angle improved significantly (p < 0.001) from preoperative 54 ± 15° to postoperative 4 ± 2°.
    UNASSIGNED: MRI-based 3D models were feasible for SCFE patients. Three-dimensional models could be useful for severe SCFE patients for preoperative 3D printing and deformity analysis and for ROM simulation. This could aid for patient-specific diagnosis, treatment decisions, and preoperative planning. MRI-based 3D models are radiation-free and could be used instead of CT-based 3D models in the future.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    无血管坏死,严重的滑脱股骨骨phy(SCFE)并发症,很难治疗。我们报告了一名12岁男性患者的坏死股骨头血运重建的罕见病例,患有严重的SCFE(后倾角,87°)。我们执行了修改的Dunn程序(MDP),其次是长期卸载治疗。术后2.3年部分恢复到骨phy的血流。在最后的4.5年随访中,血流已经恢复,导致骨phy闭合,无明显的股骨头畸形或髋部疼痛。病人可以在没有帮助的情况下行走,具有120°的屈曲范围。这些发现支持将MDP与长期卸载疗法一起用作严重SCFE的潜在治疗选择。
    Avascular necrosis, a serious slipped capital femoral epiphysis (SCFE) complication, is difficult to treat. We report a rare case of revascularization of the necrotic femoral head in a 12-year-old male patient with a severe SCFE (posterior tilting angle, 87°). We performed the modified Dunn procedure (MDP), followed by long-term unloading therapy. Blood flow to the epiphysis had partially resumed 2.3 years postoperatively. At the final 4.5-year follow-up, blood flow had been restored, leading to epiphyseal closure without significant femoral head deformity or hip pain. The patient could walk unassisted, with a flexion range of 120°. These findings support the use of the MDP with long-term unloading therapy as a potential treatment option for severe SCFE.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    假性甲状旁腺功能减退症是一种罕见的疾病,其特征是对完整的甲状旁腺激素(PTH)的终末器官抵抗,并伴有低钙血症和高磷血症的实验室发现。该疾病的放射学证据可表现为多种骨异常。该病例描述了一名11岁的女性,有修复的双侧滑脱股骨骨epi病史,双侧上肢的活动范围有限。实验室检查结果与假性甲状旁腺功能减退症一致。X线照片显示双侧锁骨头和多根肋骨的软骨下吸收以及肱骨近端干干mis端的带状透明,伴有内翻骨畸形和肱骨头下半脱位。此演示文稿增加了假性甲状旁腺功能减退症的潜在影像学表现。
    Pseudohypoparathyroidism is a rare disorder characterized by end-organ resistance to intact parathyroid hormone (PTH) and concomitant laboratory findings of hypocalcemia and hyperphosphatemia. Radiologic evidence of the disease may manifest as a variety of bone abnormalities. This case describes an 11-year-old female with a history of repaired bilateral slipped capital femoral epiphysis who presented with a limited range of motion of the bilateral upper extremities. Laboratory findings were consistent with pseudohypoparathyroidism. Radiographs revealed subchondral resorption of bilateral clavicular heads and multiple ribs and band lucencies of proximal humeral metaphyses, along with vara deformity and inferior subluxation of the humeral heads. This presentation adds to the spectrum of potential radiographic manifestations of pseudohypoparathyroidism.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:在进行Imhäuser截骨术的滑脱股骨干(SCFE)患者中,股骨头的准确重新定位非常具有挑战性。这项研究的目的是确定术前3D计划和3D打印的手术指南是否可以提高股骨头放置的准确性。
    方法:这项回顾性研究比较了2009年至2013年进行经典Imhäuser截骨手术的患者与2014年至2021年使用3D术前计划和3D打印手术指南进行Imhäuser截骨手术的患者的结果参数。主要终点是髋关节运动范围(ROM)的改善。次要结果是影像学改善(Southwick角度),患者报告的关于髋部和社会心理主诉的临床结局,用两份问卷和手术时间进行评估.
    结果:与Imhäuser组的7例患者相比,3D组的14例患者的影像学改善程度稍大,手术时间稍短。在ROM中没有发现差异,患者报告的临床结局略差.
    结论:令人惊讶的是,我们没有发现两组之间的显著差异。需要进一步研究使用3D计划3D打印的手术指南。
    背景:这项研究获得了两家医院当地伦理委员会的批准。
    BACKGROUND: Accurate repositioning of the femoral head in patients with Slipped Capital Femoral Epiphysis (SCFE) undergoing Imhäuser osteotomy is very challenging. The objective of this study is to determine if preoperative 3D planning and a 3D-printed surgical guide improve the accuracy of the placement of the femoral head.
    METHODS: This retrospective study compared outcome parameters of patients who underwent a classic Imhäuser osteotomy from 2009 to 2013 with those who underwent an Imhäuser osteotomy using 3D preoperative planning and 3D-printed surgical guides from 2014 to 2021. The primary endpoint was improvement in Range of Motion (ROM) of the hip. Secondary outcomes were radiographic improvement (Southwick angle), patient-reported clinical outcomes regarding hip and psychosocial complaints assessed with two questionnaires and duration of surgery.
    RESULTS: In the 14 patients of the 3D group radiographic improvement was slightly greater and duration of surgery was slightly shorter than in the 7 patients of the classis Imhäuser group. No difference was found in the ROM, and patient reported clinical outcomes were slightly less favourable.
    CONCLUSIONS: Surprisingly we didn\'t find a significant difference between the two groups. Further research on the use of 3D planning an 3D-printed surgical guides is needed.
    BACKGROUND: Approval for this study was obtained of the local ethics committees of both hospitals.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:在患有慢性滑脱性股骨骨epi(C-SCFE)的患者中,进行大底截骨术是纠正股骨近端畸形的有效方法。然而,术后并发症发生率很高,与医源性股骨头缺血性坏死(AVN)是最麻烦的。为了克服AVN的风险,根据Ganz和修改的Dunn程序,最近,血管保留资本下截骨术(VASSCO)技术已经被提出;然而,对于正在使用的后一种技术,只有短期随访研究可用.因此,这项研究的目的是显示我们使用VASSCO技术的中期临床和放射学结果。材料与方法:2012年至2016年4月,共有26例患者接受VASSCO治疗中度或重度稳定期C-SCFE,平均随访10年(8-12年)。使用HHS以及术前和术后ROM评估结果。收集放射学结果和并发症。结果:术中无重大并发症发生;3例患者报告术后短暂性股外侧皮神经失用症,在六个月内完全康复。所有放射学结果显示术后有实质性改善。1例患者发生股骨头AVN,12年后需要进行全髋关节置换术。结论:目前的数据表明,VASSCO截骨术是一种可靠的技术,在中期随访中具有很好的临床效果;它可以被认为是使用更复杂的技术来恢复中重度C-SCFE的股骨近端解剖结构的一种有价值的替代方法。
    Background: In patients affected by chronic slipped capital femoral epiphysis (C-SCFE), the performance of a subcapital osteotomy is an effective procedure to correct the deformity at the proximal femur. However, the rate of postoperative complications is very high, with iatrogenic avascular necrosis of the femoral head (AVN) being the most bothersome. To overcome the risk of AVN, the modified Dunn procedure according to Ganz and, more recently, the Vascular Sparing Subcapital Osteotomy (VASSCO) technique have been proposed; however, only short-term follow-up studies are available on the latter technique being used. The aim of this study is therefore to show our mid-term clinical and radiological results with the VASSCO technique. Materials and Methods: A total of 26 patients underwent VASSCO for moderate or severe stable C-SCFE between 2012 and April 2016 with an average 10-year follow-up (range 8-12 years). The outcomes was evaluated using the HHS and pre- and postoperative ROM. The radiological outcomes and complications were collected. Results: No major intraoperative complications occurred; three patients reported postoperative transient apraxia of the lateral femoral cutaneous nerve, which completely recovered in six months. All the radiological outcomes showed substantial improvement postoperatively. One case patient developed AVN of the femoral head and required a total hip arthroplasty after 12 years. Conclusions: The current data suggest that VASSCO osteotomy is a reliable technique with very good clinical results at mid-term follow-up; it could be considered a valuable alternative to using more complex techniques to restore the proximal femoral anatomy in moderate to severe C-SCFE.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    这项研究介绍了一例罕见的单侧滑脱股骨骨的病例,该病例经手术治疗,患有脑瘫的5岁男孩在妊娠27周时出生,发展为III级脑室内出血和脑室周围白质软化症,并正在服用抗癫痫药物。包括丙戊酸和左乙拉西坦>3年。患者无内分泌史,肾,和严重的家族性疾病。
    This study presents a rare case of unilateral slipped capital femoral epiphysis treated surgically in a 5-year-old boy with cerebral palsy who was born at 27 weeks\' gestation and developed grade III intraventricular haemorrhage and periventricular leucomalacia and was on antiepileptic drugs, including valproic acid and levetiracetam for >3 years. The patient had no history of endocrine, renal, and significant familial diseases.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

公众号