获取皮肤移植物后的供体部位的管理是一个重要问题,因为患者通常在供体部位比受体部位报告更多的不适。有,然而,大量的敷料可用于供体部位的治疗和管理,然而,对于这些部分厚度的伤口,没有广泛接受的方法。已发现蜂蜜可用于治疗烧伤和其他伤口,分裂厚度的皮肤移植供体部位就像部分厚度烧伤伤口,蜂蜜对烧伤伤口的愈合效果也可以在这些类型的伤口上预期。因此,这项研究是为了评估蜂蜜对皮肤移植供体部位的影响。从2002年到2004年,100例因各种原因接受皮肤移植的患者组成了随机研究的材料,分为两组,每组50例,分别为蜂蜜治疗组和凡士林纱布治疗组。移植物供体部位面积30~48cm(2),平均32.6厘米(2)。在用蜂蜜治疗的组中,90%的患者没有或只有中度疼痛,而在用凡士林纱布治疗的组中,88%的患者无疼痛或轻度疼痛(p>0.001,不显著)。两组患者均无过敏反应。在第7天开药时,48例患者发生上皮形成,而第2组为39例,即用凡士林纱布处理的供体部位(p<0.05,统计学显著)。到第十天,蜂蜜治疗组的伤口全部愈合,而在凡士林纱布治疗组中,76%的伤口愈合(p<0.05)。在1个月的随访中,两组的结果具有可比性,关于患者满意度。总之,蜂蜜浸渍纱布引起较少的疼痛和愈合供体部位的伤口更快,具有良好的美容效果。
The management of the donor site after harvesting a skin graft is an important issue, as patients often report more discomfort at the donor site than at the recipient site. There is, however, a plethora of dressings available for the treatment and management of donor sites, yet, there is no widely accepted method established for these partial thickness wounds. Honey has been found to be useful in the treatment of burns and other wounds, split-thickness skin graft donor sites are like partial thickness burn wounds and honey\'s healing effect on burn wound can also be expected on these types of wounds. Therefore, this study was undertaken to evaluate the effect of honey on skin graft donor sites. From 2002 to 2004, 100 patients who have undergone skin grafting for various reasons formed the material of the randomized study divided into two groups of 50 each in honey-treated group and Vaseline gauze-treated group. Graft donor site area ranged from 30 to 48 cm(2), mean 32.6 cm(2). In the group treated with honey, 90 % of the patients had nil or only moderate pain, whereas in the group treated with Vaseline gauze,88 % had nil or mild pain (p > 0.001, not significant). There were no allergic reactions in any of the patients in either group. On opening of the dressing on the 7th day, epithelialization has occurred in 48 patients as compared to 39 in group 2, i.e., donor sites treated with Vaseline gauze (p < 0.05, statistically significant). By the 10th day, all the wounds healed in honey-treated group, whereas 76 % of wounds healed in Vaseline gauze-treated group (p < 0.05). At 1 month follow-up, the results were comparable in both groups, with regard to patient satisfaction. In conclusion, honey-impregnated gauze causes less pain and heals donor sites wounds faster with good cosmetic result.