背景:全氟烷基和多氟烷基物质(PFAS)是一组具有多种功能特性的合成化学品,由于其广泛使用,在我们的环境中无处不在。PFAS暴露与不良健康影响有关,因此,了解暴露可能如何发生至关重要。许多研究都集中在饮用水的环境暴露上,但是关于吸入暴露的数据很少,尤其是在职业环境中。
方法:在本研究中,通过全面的文献检索,测得的空气传播(即,气溶胶,挥发物,和粉尘)汇总了各种职业的吸入暴露和区域水平,以比较报告的PFAS暴露水平。在滑雪打蜡等各种职业中测量的机载PFAS水平,纺织制造业,消防,和地板打蜡进行了分析和比较。
结果:本综述的结果表明,工人经历不同程度的PFAS暴露取决于工作场所和行业以及工作场所内执行的工作任务。在所有职业中,与所有其他报告的职业和住宅暴露相比,滑雪打蜡表现出最高的PFAS空气传播总浓度。
结论:建议进行进一步研究,以评估所审查职业中PFAS暴露的风险,并确定其他有PFAS暴露风险的潜在职业。此外,应制定实施安全措施的知情建议,以保护工人免受不利健康影响。
Per- and polyfluoroalkyl substances (PFAS) are a group of synthetically-made chemicals with diverse functional properties that have become ubiquitous in our environment because of their widespread use. PFAS exposure has been associated with adverse health effects, and it is therefore vital to know how exposure may occur. Many studies have focused on environmental exposure from drinking water, but there is a paucity of data on inhalation exposure, especially in occupational settings.
In this study, through a comprehensive literature search, measured airborne (i.e., aerosols, volatiles, and dust) inhalation exposure and area levels were compiled for various occupations to compare reported levels of PFAS exposure. Airborne PFAS levels measured in various occupations such as ski waxing, textile manufacturing, firefighting, and floor waxing were analyzed and compared.
Results of this review demonstrate that workers experience varying levels of PFAS exposure contingent on the workplace and industry and the work tasks performed within the workplace. Out of all occupations, ski waxing exhibited the highest total PFAS airborne concentrations when compared to all other reported occupational and residential exposures.
Further research is recommended to estimate the risk of PFAS exposures in the occupations reviewed and to identify other potential occupations at risk of PFAS exposure. In addition, informed recommendations to implement safety measures ought to be developed to protect workers from adverse health effects.