(1)背景:男性脑脊液(CSF)/血清白蛋白商(QAlb)和脑脊液总蛋白(TP)高于女性。这被认为是由于性别之间的人体测量差异。本研究旨在探讨QAlb和CSFTP与身高的关系。体重,体重指数(BMI)。(2)方法:共207例患者纳入研究,并对临床诊断进行分析。(3)结果:运行多变量线性回归以预测年龄的对数转换Qalb和对数转换的CSFTP值,性别,体重,和身高(第一个模型)或年龄,性别,和BMI(第二模型)。在这两种模型中,年龄(β=0.004,95%CI=0.002至0.006)和性别(β=-0.095,95%CI=-0.169至-0.021,β=-0.135,95%CI=-0.191至-0.079)是QAlb的重要预测因子,但是体重,高度,BMI没有。同样,年龄(β=0.004,95%CI=0.003~0.006)和性别(β=-0.077,95%CI=-0.142~-0.013,β=-0.109,95%CI=-0.157~-0.060)是CSFTP的显著预测因子,而人体测量特征没有。当按BMI状态对男性和女性进行分组时,QAlb和CSFTP没有差异。(4)结论:我们的数据表明,人体测量特征不能解释QAlb和CSFTP的性别相关差异。
(1) Background: Cerebrospinal fluid (CSF)/serum albumin quotient (QAlb) and CSF total protein (TP) are more elevated in males than females, and this has been hypothesised to be due to anthropometric differences between the sexes. This study aimed to investigate QAlb and CSF TP as a function of body height, weight, and body mass index (BMI). (2) Methods: A total of 207 patients were included in the study and analysed blinded to clinical diagnosis. (3) Results: Multivariable linear regressions were run to predict log-transformed Qalb and log-transformed CSF TP value from age, sex, weight, and height (first model) or from age, sex, and BMI (second model). In both models, age (β = 0.004, 95% CI = 0.002 to 0.006) and sex (β = -0.095, 95% CI = -0.169 to -0.021, and β = -0.135, 95% CI = -0.191 to -0.079) were significant predictors for QAlb, but weight, height, and BMI were not. Similarly, age (β = 0.004, 95% CI = 0.003 to 0.006) and sex (β = -0.077, 95% CI = -0.142 to -0.013, and β = -0.109, 95% CI = -0.157 to -0.060) were significant predictors for CSF TP, while anthropometric characteristics were not. No differences in QAlb and CSF TP were found when grouping males and females by BMI status. (4) Conclusions: Our data suggest that anthropometric characteristics could not explain the sex-related differences in QAlb and CSF TP.