贫血是妊娠期最常见的营养疾病,具有严重的不良母胎结局。本研究的目的是研究COVID-19大流行对重度贫血妇女妊娠结局的影响。
■在LHMC和SSK医院的妇产科进行了一项回顾性观察性研究,德里。该研究包括所有产前妇女,其出生年龄>26周(妊娠晚期),患有严重贫血和血红蛋白水平为7g/dL。在我们的研究中,在研究期间(2022年7月至12月)共纳入4031名女性作为病例,在COVID-19前期(2019年7月至12月)纳入6,659名女性作为对照.
■在本研究中,研究期间共有4031名妇女分娩,而对照期间为6659名.在本研究中,研究组贫血患病率为74.7%,对照组为51.6%(P<0.001).研究组平均血红蛋白水平明显低于对照组,P<0.05。小细胞性低色素性贫血是两组中最常见的贫血形态类型。血清铁蛋白,血清铁,与对照组相比,病例中的血清B12和叶酸水平显着降低(P<0.05)。研究组中胎儿生长受限的几率是对照组的1.4倍。与对照组相比,新生儿并发症(例如低出生体重)的几率为2.49(95%CI:1.04-5.91),需要入托或NICU的几率为4.84倍(95%CI:0.48-48.24)。病例的低出生率较高,发现具有统计学意义。
■COVID-19大流行对重度贫血妇女的不良母婴结局有间接影响。
UNASSIGNED: Anemia is the most common nutritional disease in pregnancy with significant adverse maternofetal outcome. The objective of the present study is to study the impact of COVID-19 pandemic on the pregnancy outcomes of women with severe anemia.
UNASSIGNED: A retrospective observational study was conducted in the Department of Obstetrics and Gynaecology at LHMC and SSK Hospital, Delhi. The study included all antenatal women admitted at a gestational age of >26 weeks (third trimester) with severe anemia and hemoglobin level of 7 g/dL. In our study, a total of 4031 women were included as cases during study period (July to December 2022) and 6659 women as controls from pre-COVID-19 period (July to December 2019).
UNASSIGNED: In present study, a total of 4031 women delivered during study period as compared to 6659 in control period. In the present study, the prevalence of anemia was observed to be 74.7% in the study group and 51.6% in the control group (P < 0.001). Mean hemoglobin level was significantly lower in study group as compared to the control groups P<0.05. Microcytic hypochromic anemia was the most common morphological type of anemia in both groups. Serum ferritin, serum iron, serum B12, and folic acid levels among cases were significantly (P < 0.05) lower as compared to controls. Odds of fetal growth restriction were 1.4 times higher among study group as compared to control groups. The odds of newborn complications such as low birth weight were 2.49 (95% CI: 1.04-5.91) and need for nursery or NICU admission were 4.84 times (95% CI: 0.48-48.24) higher in cases as compared to controls. Low birth rate was higher in cases and was found to be statistically significant.
UNASSIGNED: COVID-19 pandemic had indirect impact on adverse maternal and fetal outcome in women with severe anemia.