service improvement

  • 文章类型: Journal Article
    背景:在英国,痴呆症的患病率越来越高,这给医疗保健带来了巨大的挑战。预计到2025年,受影响的个人将超过100万人,每年花费NHS63亿英镑。痴呆症患者住院很常见,占据约25%的英国医院病床,导致住院时间延长和健康状况下降。
    方法:本文介绍了开场阶段,这是一个更大的项目的一部分,患者和公众参与和参与(PPIE)被用来理解和导航对痴呆症患者的医院护理意味着什么。了解医院对痴呆症患者的护理,从2023年2月至7月,通过埃塞克斯和萨福克的痴呆症咖啡馆进行了焦点小组参与患者,照顾者和家庭成员。
    结果:使用了公认的PPIE报告和主题分析流程,并确定了有关医院护理的六个主题和21个子主题:个性化护理,照顾者的角色,基本护理,人际交往,信息共享和人员配备。
    结论:PPIE的结果将用于在项目的下一阶段通知利益相关者并与之合作,这包括检查医院的护理过程,确定接触点并评估这些区域。该项目继续得到包括痴呆症患者在内的利益相关者的信息,照顾者和工作人员。此外,结果可能会通知其他服务提供者加强护理,流程和交付。
    结论:展望未来,该研究强调了与痴呆症护理相关利益相关者建立合作关系的重要性.此外,它为重点领域提供了见解,这些领域对于急性护理组织在向痴呆症患者提供护理时至关重要。通过纳入PPIE的见解,该项目旨在确定痴呆症护理服务中的不平等,改善痴呆症患者的医院护理,培养更具包容性和支持性的医疗保健环境。
    这项研究的目的是探索有关痴呆症患者的医院护理的最重要问题,他们的照顾者和家人。痴呆症患者,护理人员和家庭成员通过社区痴呆症咖啡馆参与了这项研究,并被招募参加焦点小组讨论痴呆症患者的医院护理.讨论的问题和材料的设计是通过与大学部门的服务用户负责人和痴呆症专家协商制定的,并由患有痴呆症的服务用户成员进行审查。与一组护理人员进行了试点焦点小组。我们与痴呆症咖啡馆经理合作,协调招聘和合适的环境来管理焦点小组。
    背景:不适用。
    BACKGROUND: The increasing prevalence of dementia in the United Kingdom presents significant challenges for healthcare, with projections estimating over a million affected individuals by 2025, costing the NHS £6.3 billion annually. Hospital admissions among dementia patients are common, occupying about 25% of UK hospital beds and leading to prolonged stays and diminished health outcomes.
    METHODS: This paper presents the opening stages, part of a larger project where Patient and Public Involvement and Engagement (PPIE) was employed to understand and navigate what it means for hospital care for a person living with dementia. To understand hospital care for dementia patients, focus groups were conducted through dementia cafés in Essex and Suffolk from February to July 2023 engaging patients, carers and family members.
    RESULTS: Recognised processes for reporting PPIE and thematic analysis were used and identified six themes and 21 subthemes regarding hospital care: individualised care, role of carers, basic care, interpersonal communication, information sharing and staffing.
    CONCLUSIONS: The results from the PPIE will be used to inform and work with stakeholders through the next phases of the project, which involves examining care processes in the hospital, identifying touchpoints and evaluating these areas. The project continues to be informed by stakeholders including people living with dementia, carers and staff. Additionally, the results may inform other service providers for care enhancements, processes and delivery.
    CONCLUSIONS: Moving forward, the study emphasises the importance of building collaborative relationships with stakeholders involved in dementia care. Additionally, it provides insights to focus areas that are fundamental for acute care organisations when delivering care to people living with dementia. By incorporating insights from PPIE, this project seeks to identify inequalities in dementia care services, improve hospital care for people living with dementia, fostering a more inclusive and supportive healthcare environment.
    UNASSIGNED: The purpose of the study was to explore the most important issues around hospital care for people with dementia, their carers and families. Persons living with dementia, carers and family members were involved in the study through community dementia cafés and recruited to take part in focus groups to discuss hospital care for patients with dementia. The design of questions and materials for the discussions was developed through consultation with the university department\'s service user lead and dementia specialist and reviewed by a service user member living with dementia. A pilot focus group was conducted with a group of carers. We worked with the dementia café managers to coordinate recruitment and a suitable environment to run the focus groups.
    BACKGROUND: Not applicable.
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  • 文章类型: Journal Article
    唐卡斯特的0-19照顾儿童(LAC)队,英格兰,是一项完善的服务,随着时间的推移而发展起来,以确定和解决被照顾的儿童和年轻人以及护理离职者的健康需求。其目的是通过提供全面的方法来评估这些儿童和年轻人的健康和福祉,从而改善他们的成果。在每个儿童或年轻人的整个护理过程中,为LAC配备专门的护士专家的原则可以建立信任关系,并听到儿童或年轻人的声音。本文报道了唐卡斯特LAC团队的一些发展,包括联合护士和全科医生初步健康评估的当地试点,以及参与心理健康评估的国家试点。
    The 0-19 looked after children (LAC) team in Doncaster, England, is a well-established service that has developed over time to identify and address the health needs of looked after children and young people and care leavers. Its aims are to improve outcomes for these children and young people by offering a holistic approach to assessing their health and well-being. The principle of having a dedicated nurse specialist for LAC following each child or young person throughout their care journey enables a trusting relationship to be established and the voice of the child or young person to be heard. This article reports on several developments in the Doncaster LAC team, including a local pilot of joint nurse and GP initial health assessments and participation in a national pilot of mental health assessments.
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  • 文章类型: Journal Article
    本文探讨了护理信息官(NIO)团队在促进伦敦两个NHS信托机构向电子健康记录系统(EHR)过渡方面所发挥的关键作用。文章强调,随着数字领导力在护理中的重要性日益提高,有必要为实施EHR做好护理人员的准备,以增强患者护理和员工体验。它讨论了NIO团队采用的各种方法,包括\'表演和讲述\',演示,walkabout,诱导会议,\'CopyCat\'图表,以及一份“变更和约定”文档。这些参与策略旨在满足不同的学习需求,增加护士的信心,并确保有效使用新的EHR。EHR的成功实施取决于护理人员之间的协作努力,领导和NIO团队。这强调了在应对医疗技术复杂性方面拥抱数字化转型和创新战略的重要性。
    This article explores the critical role the nursing information officer (NIO)\'s team played in facilitating the transition to an electronic health record system (EHR) at two NHS trusts in London. The article highlights that with the increasing importance of digital leadership in nursing, it is necessary to prepare nursing staff for the implementation of an EHR to enhance patient care and staff experience. It discusses various methodologies the NIO\'s team adopted, including \'show and tells\', demos, walkabouts, induction sessions, \'CopyCat\' charting, and a \'change and engagement\' document. These engagement strategies are aimed at addressing diverse learning needs, increasing nurses\' confidence and ensuring effective use of the new EHR. The successful implementation of an EHR depends on collaborative efforts among nursing staff, leadership and NIO teams. This emphasises the importance of embracing digital transformation and innovative strategies in navigating healthcare technology complexities.
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  • 文章类型: Journal Article
    远程医疗诊所已被用于许多专业,包括神经外科,改善农村社区患者的获取。引入与病人有关的护士导航员之前,在临床期间和之后进行评估。诊所在一家乡村医院举行,一名护士导航员和病人一起出现在诊所,和医生远程咨询。在十家远程医疗诊所之后,进行了患者满意度调查和审核。通过11个问题的结构化调查,能够与31名(68%)新患者联系。21人中有18人(86%)表示,与当面诊所相比,他们对诊所的质量感到满意。18/21患者(86%)的总体满意度评分为7-10分,评分为1-10分。对于去农村医院诊所而不是神经外科中心的患者,估计节省了10785公里的旅行。这项研究表明,护士导航员在整个患者远程健康诊所路径中的支持作用值得进一步评估。
    Telehealth clinics have been used in many specialities, including neurosurgery, to improve access for patients in rural communities. The introduction of nurse navigators involved with the patient before, during and after the clinic was evaluated. Clinics were held in a rural hospital with a nurse navigator present in the clinic with the patient, and the physician consulting remotely. A patient satisfaction survey and audit were conducted following ten telehealth clinics. Twenty-one new patients were able to be contacted out of 31 (68%) with an 11 question structured survey. Eighteen out of 21 (86%) stated they were satisfied with the quality of the clinic compared with an in-person clinic. Overall satisfaction scores of 7-10 were scored by 18/21 patients (86%) on a scale of 1-10. An estimated 10785 km of travel was saved for patients going to a rural hospital clinic rather than the neurosurgical centre. This study shows that the supportive role of nurse navigators throughout the patient telehealth clinic pathway merits further continuing evaluation.
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  • 文章类型: Journal Article
    本研究的目的是开发医院-利益相关者合作(HSC)工具和医院绩效因子(HPF)工具,以探索利益相关者对医院服务改进的看法和价值。
    这项探索性混合方法研究涉及三个步骤:初始工具开发(步骤1),有效性测试(步骤2),和模块开发(步骤3)。在步骤1中,通过文献综述收集定性数据,焦点小组讨论,与医院管理专家的访谈导致了初步工具的创建。步骤2包括由α5人专家小组进行的定性分析,随后对36名受访者进行有效性的定量分析(皮尔逊相关性,α=0.05)和可靠性(Cronbach'sAlpha,α=0.6)试验。步骤3包含最终的模块开发。
    HSC工具包含6个域,HPF工具包含4个透视图。这6个HSC领域是:1)利益相关者识别,2)互动对话,3)承诺,4)规划、5)执行,6)行动和行为的变化。HPF的4个观点是:1)利益相关者的观点,2)财务观点,3)内部业务流程,4)人员和组织能力。HSC工具有效性和可靠性测试的值分别约为0.0046和0.995。此外,HPF工具有效性和可靠性测试的值分别约为0.0062和0.995。
    本研究通过分析医院利益相关者的直接反馈和衡量医院绩效因素,为改善服务的需求评估提供了一种实用工具。
    UNASSIGNED: The purpose of this study was to develop the Hospital-Stakeholder Collaboration (HSC) Tool and Hospital Performance Factor (HPF) Tool to explore stakeholder perception and value for hospital service improvement.
    UNASSIGNED: This exploratory mixed-method study involved three steps: initial tool development (Step 1), validity testing (Step 2), and module development (Step 3). In Step 1, qualitative data collection through literature reviews, focus group discussions, and interviews with hospital management experts led to the creation of the preliminary tools. Step 2 involved qualitative analysis by α 5-member expert panel, followed by quantitative analysis with 36 respondents for validity (Pearson correlation, α = 0.05) and reliability (Cronbach\'s Alpha, α = 0.6) tests. Step 3 encompassed the final module development.
    UNASSIGNED: The HSC tool contains 6 domains and the HPF tool contains 4 perspectives. The 6 HSC domains were: 1) stakeholder identification, 2) interactive dialogue, 3) commitment, 4) planning, 5) implementation, 6) change in action and behavior. The 4 HPF perspectives were: 1) stakeholder perspective, 2) financial perspective, 3) internal business process, and 4) staff and organizational capacity. The values of the HSC tool validity and reliability tests were around 0,0046 and around 0,995, respectively. Additionally, the values of the HPF tool validity and reliability tests were around 0,0062 and around 0,995, respectively.
    UNASSIGNED: This study offers a practical tool for needs assessment for the improvement of service by analyzing direct feedback from hospital stakeholders and measuring hospital performance factors.
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  • 文章类型: Journal Article
    这项研究集中在早期癌症研究的专业-临床研究的分支,专注于第一阶段和第二阶段临床试验。目的是了解在新转诊的早期癌症临床试验患者的临床路径中实施教育干预所涉及的工作的复杂性。5月和芬奇归一化过程理论(NPT)被用来理解,开发和评估在转诊医院站点嵌入教育资源的过程。评估中出现的要素提供了对所进行的实施工作复杂性的见解。主要因素是:与大流行有关的挑战,变更管理,领导力,共同的目标,团队合作,劳动力能力和患者结果。调查结果揭示了实施教育资源的障碍或促进者。
    This research is centred in the specialty of early phase cancer research - the branch of clinical research that focuses on phase one and phase two clinical trials. The aim was to gain an understanding of the complexity of work involved in implementing an educational intervention within the clinical pathway for newly referred early phase cancer clinical trial patients. The May and Finch Normalisation Process Theory (NPT) was used to understand, develop and evaluate the process of embedding an educational resource at referral hospital sites. Elements emerged from the evaluation that provide insights into the complexity of the implementation work that took place. The main elements were: pandemic-related challenges, change management, leadership, shared purpose, teamwork, workforce capacity and patient outcomes. The findings shed light on the barriers to or facilitators of the implementation of the educational resource.
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  • 文章类型: Journal Article
    目的:系统回顾类型学,影响,证据质量,障碍,和促进在低收入和中等收入国家(LMICs)实施成人重症监护质量改进(QI)干预措施。
    方法:MEDLINE,EMBASE,Cochrane图书馆和ClinicalTrials.gov于2022年9月1日进行了搜索。如果这些研究描述了在LMIC中对成人重症监护实施QI干预措施,全文提供,在2000年后出版的英文。使用ROB2.0/ROBINS-I工具评估偏倚风险。干预策略根据知识翻译框架进行分类。干预效果通过计票来综合,并用二项检验进行评估。使用实施研究综合框架对实施的障碍和促进者进行了叙述综合。
    结果:共纳入78项研究。偏倚的风险很高。最常见的干预策略是教育,审核和反馈(A&F)和协议/指南/捆绑包/清单(PGBC)。两个多方面的策略改善了过程和结果指标:教育和A&F(p=0.008);PGBC与教育和A&F(p=0.001,p<0.001)。执行的促进者是利益相关者的参与,组织准备实施,和干预措施的适应性。障碍是缺乏资源和与当地系统不兼容。低收入国家缺乏证据。
    结论:在低收入国家的重症监护中,QI的证据很少,而且偏倚的风险很高,但表明多方面的干预措施是最有效的。与利益相关者共同设计干预措施并参与其中,传达相对优势,雇用本地冠军并适应反馈可以改善实施情况。混合研究设计,过程评估和遵守报告指南将改善证据基础。
    OBJECTIVE: To systematically review the typology, impact, quality of evidence, barriers, and facilitators to implementation of Quality Improvement (QI) interventions for adult critical care in low- and middle-income countries (LMICs).
    METHODS: MEDLINE, EMBASE, Cochrane Library and ClinicalTrials.gov were searched on 1st September 2022. The studies were included if they described the implementation of QI interventions for adult critical care in LMICs, available as full text, in English and published after 2000. The risks of bias were assessed using the ROB 2.0/ROBINS-I tools. Intervention strategies were categorised according to a Knowledge Translation framework. Interventions\' effectiveness were synthesised by vote counting and assessed with a binomial test. Barriers and facilitators to implementation were narratively synthesised using the Consolidated Framework for Implementation Research.
    RESULTS: 78 studies were included. Risk of bias was high. The most common intervention strategies were Education, Audit & Feedback (A&F) and Protocols/Guidelines/Bundles/Checklists (PGBC). Two multifaceted strategies improved both process and outcome measures: Education and A&F (p = 0.008); and PGBC with Education and A&F (p = 0.001, p < 0.001). Facilitators to implementation were stakeholder engagement, organisational readiness for implementation, and adaptability of interventions. Barriers were lack of resources and incompatibility with clinical workflows.
    CONCLUSIONS: The evidence for QI in critical care in LMICs is sparse and at high risk of bias but suggests that multifaceted interventions are most effective. Co-designing interventions with and engaging stakeholders, communicating relative advantages, employing local champions and adapting to feedback can improve implementation. Hybrid study designs, process evaluations and adherence to reporting guidelines would improve the evidence base.
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  • 文章类型: Journal Article
    评估高级执业护士与医师主导/常规护理(由医生或非高级执业护士管理的护理)相比的作用的有效性。
    高级执业护士为改善患者护理质量做出了贡献,并具有优化全球人群健康的巨大潜力。自从国际护士理事会正式认可高级执业护士以来,其中,这一角色已被大多数科室和临床专科采用,特别是在高收入国家。
    主要研究证据的系统评价。
    MEDLINE,EMBASE,CINAHL,Cochrane登记处,Cochrane试验,我们在CochraneEPOC(PDQEvidence)中搜索了与高级执业护士相关的患者护理和卫生资源利用结局的随机对照试验(RCT).
    审查是根据系统审查和荟萃分析(PRISMA)声明的首选报告项目进行的。选择的文章仅限于过去20年发表的全文英语语言试验,纳入常规护理比较器。搜索词仅限于高级护士从业者角色和实践的变化。符合条件的研究采用建议分级进行偏倚风险评估和质量评估,评估,开发和评估(等级)。使用叙述性综合分析临床和服务结果,因为研究之间的明显异质性排除了荟萃分析。
    对13项随机对照试验进行了综述。所有这些都是在高收入国家的初级保健和医院环境中进行的,涉及儿科和成年患者。五项试验被评估为高质量,八个质量低到中等。高级护士从业人员对日常护理的影响表现出积极作用;对于消化不良,平均差异[MD]2.3:95%CI1.4,3.1]),对健康状况的看法[(MD-140.6;95%CI-184.8,-96.5)],满意度[(MD范围为-8.79;95%CI-13.59,-3.98至0.61;95%CI-4.84,6.05)],物理功能(1.58[SD0.76]v.1.81[SD0.90]),观察血压控制(收缩压[133[SD21]v.135[SD19]mmHgp=0.04]和舒张压[77[SD10]v.80[SD11]mmHgp=0.007])。与服务提供相关的积极影响包括提高患者满意度,减少等待时间和成本,显着有利于高级护士从业人员(所有p<0.05)。
    本综述的证据支持高级执业护士对临床和服务相关结果的积极影响:患者满意度,等待时间,控制慢性病,和成本效益,特别是当直接与医生主导的护理和常规护理实践相比时-在初级,涉及成人和儿科人群的二级和专科护理设置。
    UNASSIGNED: To evaluate the effectiveness of the role of advanced nurse practitioners compared to physicians-led/ usual care (care managed by medical doctors or non-advanced nurse practitioners).
    UNASSIGNED: Advanced nurse practitioners contribute to the improvement of quality patient care and have substantial potential to optimise the health of people globally. Since the formal recognition of advanced nurse practitioners by the International Council of Nurses, among others, the role has been adopted across most departments and clinical specialties, particularly in high-income countries.
    UNASSIGNED: Systematic review of primary research evidence.
    UNASSIGNED: MEDLINE, EMBASE, CINAHL, Cochrane registry, Cochrane trials, and Cochrane EPOC (PDQ Evidence) were searched for randomised controlled trials (RCTs) of patient care and health resource utilisation outcomes associated with advanced nurse practitioners.
    UNASSIGNED: The review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) statement. The chosen articles were restricted to full-text English language trials published in the last 20 years, incorporating comparators of usual care. Search terms were limited to variations of advanced nurse practitioner role and practice. The eligible studies were bias risk assessed and quality assessed using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE). Clinical and service outcomes were analysed using narrative synthesis as the marked heterogeneity between studies precluded meta-analysis.
    UNASSIGNED: Thirteen RCTs were reviewed. All of them were conducted across high-income countries within primary care and hospital settings involving paediatric and adult patients. Five trials were assessed as high quality, and eight were of low to moderate quality. Positive effects were demonstrated for the impact of advanced nurse practitioners on usual care; for indigestion, mean difference [MD] 2.3: 95% CI 1.4, 3.1]), perceptions of health status [ (MD -140.6; 95% CI -184.8, -96.5)], satisfaction levels [ (MD ranged from -8.79; 95% CI -13.59, -3.98 to 0.61; 95% CI -4.84, 6.05)], physical function (1.58 [SD 0.76] v. 1.81 [SD 0.90]), and blood pressure control (systolic [133 [SD 21] v. 135 [SD 19] mmHg p = 0.04] and diastolic [77 [SD 10] v. 80 [SD 11] mmHg p = 0.007]) were looked at. Positive effects related to service provision included improved patient satisfaction and reductions in waiting times and costs, which significantly favored advanced nurse practitioners (all p < 0.05).
    UNASSIGNED: The evidence of this review supports the positive impact of advanced nurse practitioners on clinical and service-related outcomes: patient satisfaction, waiting times, control of chronic disease, and cost-effectiveness especially when directly compared to medical practitioner-led care and usual care practices - in primary, secondary and specialist care settings involving both adult and pediatric populations.
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  • 文章类型: Journal Article
    背景:需要改变英国(英国)提供的健康和护理服务,以更好地满足人口需求和期望,研究和创新对于推动这些转变至关重要。联合卫生专业人员(AHP)在医疗保健队伍中占很大比例。发展和扩大他们的技能和能力是提供新的工作方式的基础。然而,研究和实践相结合的职业机会仍然有限。这项研究探讨了博士学位对博士后AHP的感知效用和价值,以及他们如何将与研究相关的能力带入实践环境。
    方法:具有广泛的解释性设计,定性的横断面调查,带有封闭和开放的问题,旨在实现频率报告,同时侧重于参与者归因于该主题的重要性和意义。参与者是通过专业网络和实践社区招募的。描述性统计数据被用来分析封闭的问题回答,而组合的框架和主题分析被应用于开放问题的回答。
    结果:来自位于所有四个英国国家的71名博士后AHP的回应。研究结果在四个主要主题下进行了讨论:利用博士学位;博士学位的价值;对职业的影响,对自我和支持的影响。在适当的时候还提到了总结封闭问题回答的描述性统计数据。
    结论:这些发现清楚地阐明了博士后AHP之间的经验差异。有些人能够影响团队和组织的研究文化,支持他人发展,推动服务改进。挑战,其他人遇到的障碍和障碍反映了多年来公认的障碍。承认他们很重要,但是对话必须向前推进,并采取积极的行动,以确保在利用这些从业者带来的利益和增值方面取得更大的一致性。如果全系统转型是目标,将挑战留给个人创造力和坚韧或具有前瞻性的领导者和组织是效率低下的。迫切需要全系统作出更有效的反应,始终如一,公平地实现将研究和实践相结合的职业道路,这是英国医疗保健队伍的很大一部分。
    BACKGROUND: The need to transform the United Kingdom\'s (UK) delivery of health and care services to better meet population needs and expectations is well-established, as is the critical importance of research and innovation to drive those transformations. Allied health professionals (AHPs) represent a significant proportion of the healthcare workforce. Developing and expanding their skills and capabilities is fundamental to delivering new ways of working. However, career opportunities combining research and practice remain limited. This study explored the perceived utility and value of a doctorate to post-doctoral AHPs and how they experience bringing their research-related capabilities into practice environments.
    METHODS: With a broadly interpretivist design, a qualitatively oriented cross-sectional survey, with closed and open questions, was developed to enable frequency reporting while focusing on the significance and meaning participants attributed to the topic. Participants were recruited via professional networks and communities of practice. Descriptive statistics were used to analyse closed question responses, while combined framework and thematic analysis was applied to open question responses.
    RESULTS: Responses were received from 71 post-doctoral AHPs located across all four UK nations. Findings are discussed under four primary themes of utilisation of the doctorate; value of the doctorate; impact on career, and impact on self and support. Reference is also made at appropriate points to descriptive statistics summarising closed question responses.
    CONCLUSIONS: The findings clearly articulate variability of experiences amongst post-doctoral AHPs. Some were able to influence team and organisational research cultures, support the development of others and drive service improvement. The challenges, barriers and obstacles encountered by others reflect those that have been acknowledged for many years. Acknowledging them is important, but the conversation must move forward and generate positive action to ensure greater consistency in harnessing the benefits and value-added these practitioners bring. If system-wide transformation is the aim, it is inefficient to leave navigating challenges to individual creativity and tenacity or forward-thinking leaders and organisations. There is an urgent need for system-wide responses to more effectively, consistently and equitably enable career pathways combining research and practice for what is a substantial proportion of the UK healthcare workforce.
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  • 文章类型: Journal Article
    背景:针对阿尔茨海默病引入新的疾病修饰疗法(DMT)需要对全球大多数卫生系统的诊断和护理进行根本性的转变。了解卫生专业人员的意见,潜在患者,护理合作伙伴和纳税人对于这些新疗法的服务计划和期望管理至关重要。
    目的:调查公众和专业人士对以下方面的看法:(1)新DMT对阿尔茨海默病的可接受性;(2)对风险/收益的看法;(3)公众的支付意愿(WTP)。
    方法:由“可接受性理论框架”通知,我们对爱尔兰的1000名公众和77名卫生专业人员进行了两项在线调查.描述性和多元回归分析检查了与DMT接受和WTP相关的因素。
    结果:医疗保健专业人员的接受度(65%)高于普通公众(48%)。专业人士更关心潜在的脑出血(70%)和疗效(68%),而公众关注的是可访问性和成本。年轻参与者(18-24岁)表现出更高的WTP。教育和保险影响WTP决策。
    结论:这项研究揭示了对阿尔茨海默病的新兴DMT的复杂态度,在多个维度挑战传统智慧。令人惊讶的是,25%的公众对这些新疗法表示厌恶,尽管社会根深蒂固地担心老年痴呆症。医疗保健专业人员表现出细微的担忧,优先考虑临床有效性和潜在的脑部并发症。有趣的是,年轻,受过良好教育和私人保险的个人表现出更高的WTP,关于医疗保健公平的前景关键问题。这些多方面的发现为医疗保健战略家提供了指导,政策制定者和伦理学家,因为我们越来越接近将DMT整合到阿尔茨海默病护理中。
    BACKGROUND: Introducing new disease-modifying therapies (DMTs) for Alzheimer\'s disease demands a fundamental shift in diagnosis and care for most health systems around the world. Understanding the views of health professionals, potential patients, care partners and taxpayers is crucial for service planning and expectation management about these new therapies.
    OBJECTIVE: To investigate the public\'s and professionals\' perspectives regarding (1) acceptability of new DMTs for Alzheimer\'s disease; (2) perceptions of risk/benefits; (3) the public\'s willingness to pay (WTP).
    METHODS: Informed by the \'theoretical framework of acceptability\', we conducted two online surveys with 1000 members of the general public and 77 health professionals in Ireland. Descriptive and multivariate regression analyses examined factors associated with DMT acceptance and WTP.
    RESULTS: Healthcare professionals had a higher acceptance (65%) than the general public (48%). Professionals were more concerned about potential brain bleeds (70%) and efficacy (68%), while the public focused on accessibility and costs. Younger participants (18-24 years) displayed a higher WTP. Education and insurance affected WTP decisions.
    CONCLUSIONS: This study exposes complex attitudes toward emerging DMTs for Alzheimer\'s disease, challenging conventional wisdom in multiple dimensions. A surprising 25% of the public expressed aversion to these new treatments, despite society\'s deep-rooted fear of dementia in older age. Healthcare professionals displayed nuanced concerns, prioritising clinical effectiveness and potential brain complications. Intriguingly, younger, better-educated and privately insured individuals exhibited a greater WTP, foregrounding critical questions about healthcare equity. These multifaceted findings serve as a guidepost for healthcare strategists, policymakers and ethicists as we edge closer to integrating DMTs into Alzheimer\'s disease care.
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