scald

烫伤
  • 文章类型: Journal Article
    烫伤发生在皮肤遇到热液体或蒸汽时。虽然大多数烫伤都是偶然的,医疗提供者必须评估可能的滥用。我们报告了一例2岁女性,她因臀部烧伤而与父母一起去医院,有大便从肛门排出并被困在皮肤上的病史。医疗提供者需要考虑偶然和造成的差异,因为意外伤害确实发生在儿童身上,错误的诊断可能会产生严重的法医学后果。
    Scald burns occur when the skin encounters hot liquid or steam. Although most scald burns are accidental, the medical provider must assess for possible abuse. We report a case of a 2-year-old female who presented to the hospital with her parents due to a burn to the buttocks with a history of stool expelling from the anus and becoming trapped against the skin. Medical providers need to consider accidental and inflicted differentials, as accidental injuries do occur in children, and an incorrect diagnosis may have severe medicolegal consequences.
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  • 文章类型: Journal Article
    热损伤相关的中毒性休克综合征(TSS)是一种危及生命的疾病,可发生在烧伤后的儿童中。这项研究的目的是描述临床表现,治疗,以及热损伤后经历TSS的儿童的结局。此外,对现有文献进行了系统研究,并汇编了烧伤后发生的儿科TSS病例。2023年6月,不考虑时间限制,在几个电子数据库中搜索符合标准的文章。入选标准是英文出版物,儿科患者,并报告了临床问题的关注结果。由于所包含出版物的异质性以及缺乏适当格式的数据,荟萃分析不可行.我们的研究确定了1980年至2023年之间发表的23项研究,包括72例符合纳入标准的病例(来自多个国家)。在72例热损伤并发TSS的患者中,53名(73.6%)儿童存活,6人(8.3%)死亡,13例(18%),结果没有记录.我们的系统回顾强调了罕见的情况,严重程度,以及小儿热损伤相关TSS的复杂性。该综述的主要发现表明,小儿热损伤相关的TSS具有很高的死亡率和显着的发病率。通过提高认识,提高诊断准确性,优化治疗策略,在这种具有挑战性的情况下,医疗保健专业人员可以改善患者的预后。
    Thermal injury-associated toxic shock syndrome (TSS) is a life-threatening condition that can occur in children following burn injuries. The objective of this study was to describe the clinical manifestations, treatment, and outcomes of children who experienced TSS following a thermal injury. Additionally, the existing literature was systematically examined, and published cases of pediatric TSS occurring after burns were compiled. In June 2023, without regard for time constraints, articles that met the criteria were searched across several electronic databases. The inclusion criteria were English-language publications, pediatric patients, and reported outcomes of interest for clinical questions. Due to the heterogeneity of the included publications and the lack of data in an appropriate format, a meta-analysis was not feasible. Our research identified 23 studies published between 1980 and 2023, including 72 cases (from multiple countries) that met the inclusion criteria. Of the 72 patients with thermal injuries complicated by TSS, 53 (73.6%) children survived, 6 (8.3%) died, and for 13 (18%) cases, the outcome was not documented. Our systematic review highlights the rarity, severity, and complexity of pediatric thermal injury-associated TSS. Key findings from the review indicate that pediatric thermal injury-associated TSS carries a high mortality rate and significant morbidity. By increasing awareness, improving diagnostic accuracy, and optimizing treatment strategies, healthcare professionals can improve patient outcomes in this challenging condition.
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  • 文章类型: Journal Article
    黑麦面粉中的淀粉酶活性在黑麦面包的生产中起着至关重要的作用。在黑麦面包生产中准备烫伤时,利用非酸性黑麦麦芽来增强黑麦面粉的淀粉酶活性。这项研究研究了黑麦麦芽的去透力(DP)和浓度对黑麦粉的落落数(FN)和流变特性的影响。此外,它检查了烫伤过程和发酵过程中的还原糖。Mixolab结果提供了不同温度阶段面团特性的全面数据,突出了淀粉糊化和酶活性的显着变化,由于不同的麦芽分解能力和浓度。糊化指数(C3-C2)的下降表明淀粉糊化更快,无糖能力增加。添加黑麦麦芽显著提高了糖化和发酵烫伤中的麦芽糖含量,促进乳酸菌和酵母的有利环境。FN和Amylograph结果表明,较低的活性麦芽(DP170,179°WK),浓度为1.5%,在0.5%时可以达到与活性更高的麦芽(DP362,408°WK)相似的效果。将黑麦麦芽添加到黑麦面粉中可以调节面粉的流变特性和FN,基于麦芽DP和浓度可调。
    Amylase activity in rye flour plays a crucial role in the production of rye bread. When preparing a scald in rye bread production, diastatic rye malt is utilized to augment the amylase activity of the rye flour. This study investigated the effects of the diastatic power (DP) and concentration of rye malt on the Falling Number (FN) and the rheological properties of rye flour. Additionally, it examined reducing sugars in the scalding process and fermentation. Mixolab results provided comprehensive data on dough properties at different temperature stages, highlighting significant changes in starch gelatinization and enzyme activity due to varying malt diastatic power and concentrations. The decline in the gelatinization index (C3-C2) indicated faster starch gelatinization with increased diastatic power. Adding rye malt significantly increased maltose content in the saccharified and fermented scald, promoting a favorable environment for lactic acid bacteria and yeasts. FN and Amylograph results showed that less active malt (DP 170, 179 °WK), at a 1.5% concentration, could achieve similar effects as the more active malt (DP 362, 408 °WK) at 0.5%. Adding rye malt to rye flour allows for the regulation of the flour\'s rheological properties and FN, adjustable based on malt DP and concentration.
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  • 文章类型: Journal Article
    背景:小儿烫伤占美国烧伤中心所有入院人数的12%,是儿童最常见的烧伤类型。我们假设烧伤登记数据的地理空间分析可以识别特定的地理区域和风险因素,以集中预防伤害的工作。
    方法:从2018年1月至2023年6月,美国地区烧伤中心的烧伤登记处用于回顾性识别0-17岁的小儿烫伤患者。使用人口普查道数据对患者家庭住址进行地理编码。区域剥夺指数(ADI)被分配给人口普查区块组级别的患者。使用GetisOrdGi*统计量进行烧伤事件热点分析,以确定具有统计学意义的烧伤事件簇。
    结果:有950名儿童烫伤患者符合研究标准。该队列为52%的男性和36%的白人,中位年龄为3岁,中位总表面积为1.5%;23.8%需要住院。在多变量逻辑回归中,儿童贫困水平的增加(P=0.004)和单亲家庭中的儿童(P=0.009)与烫伤发生率的增加相关.地理空间分析确定了烧伤热点,与较高的ADI相关(P<0.001)。与白人患者相比,黑人患者更有可能入院。
    结论:烧伤登记数据的地理空间分析确定了儿童烫伤高危区域。ADI,贫穷,单亲家庭中的儿童是最大的伤害预测因子。解决这些不平等需要有针对性的伤害预防教育,加强门诊支持系统和更强大的社区资源。
    BACKGROUND: Pediatric scald burns account for 12% of all U.S. burn center admissions and are the most common type of burn in children. We hypothesized that geospatial analysis of burn registry data could identify specific geographic areas and risk factors to focus injury prevention efforts.
    METHODS: The burn registry of a U.S. regional burn center was used to retrospectively identify pediatric scald burn patients ages 0-17, from January 2018 to June 2023. Geocoding of patient home addresses with census tract data was performed. Area Deprivation Index (ADI) was assigned to patients at the census block group level. Burn incident hot spot analysis to identify statistically significant burn incident clusters was done using the Getis Ord Gi∗ statistic.
    RESULTS: There were 950 pediatric scald burn patients meeting study criteria. The cohort was 52% male and 36% White, with median age of 3 y and median total body surface area of 1.5%; 23.8% required hospital admission. On multivariable logistic regression, increased child poverty levels (P = 0.004) and children living in single-parent households (P = 0.009) were associated with increased scald burn incidence. Geospatial analysis identified burn hot spots, which were associated with higher ADI (P < 0.001). Black patients were more likely to undergo admission compared to White patients.
    CONCLUSIONS: Geospatial analysis of burn registry data identified geographic areas at high risk of pediatric scald burn. ADI, poverty, and children in single-parent households were the greatest predictors of injury. Addressing these inequalities requires targeted injury prevention education, enhanced outpatient support systems and more robust community resources.
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  • 文章类型: Journal Article
    烫伤是大麦的主要经济重要叶部病害之一,造成易感品种高达40%的产量损失。鉴定赋予抗烫伤性的数量性状基因座(QTL)和优良等位基因对于减少对大麦生产的威胁至关重要。在这项研究中,使用一组697个大麦基因型进行了全基因组关联研究(GWAS),以鉴定抗烫伤的QTL。连续三年进行了田间试验。在用于GWAS分析的不同模型中,FarmCPU被证明是最适合的模型。在六个不同的染色体上鉴定了与烫伤抗性相关的19个重要的标记性状关联(MTA)。这些MTA中的11个分别对应于先前报道的烫伤抗性基因Rrs1、Rrs4和Rrs2。在这项研究中发现了八种新的MTA,其候选基因编码了不同类型的蛋白质,包括富含亮氨酸的重复序列(LRR)。AP2/ERF转录因子,同源结构域-亮氨酸拉链,和蛋白激酶家族蛋白。鉴定的优良等位基因的组合显著降低疾病严重度评分。该结果将对开发抗烫伤品种的标记辅助育种具有一定的参考价值。
    Scald is one of the major economically important foliar diseases in barley, causing up to 40% yield loss in susceptible varieties. The identification of quantitative trait loci and elite alleles that confer resistance to scald is imperative in reducing the threats to barley production. In this study, genome-wide association studies were conducted using a panel of 697 barley genotypes to identify quantitative trait loci for scald resistance. Field experiments were conducted over three consecutive years. Among different models used for genome-wide association studies analysis, FarmCPU was shown to be the best-suited model. Nineteen significant marker-trait associations related to scald resistance were identified across six different chromosomes. Eleven of these marker-trait associations correspond to previously reported scald resistance genes Rrs1, Rrs4, and Rrs2, respectively. Eight novel marker-trait associations were identified in this study, with the candidate genes encoding a diverse class of proteins, including region leucine-rich repeats, AP2/ERF transcription factor, homeodomain-leucine zipper, and protein kinase family proteins. The combination of identified superior alleles significantly reduces disease severity scores. The results will be valuable for marker-assisted breeding for developing scald-resistant varieties.
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  • 文章类型: Journal Article
    黑麦(SecalecraineL.)是一种重要的粮食作物,饮料,和饲料,尤其是在欧洲东北部。虽然黑麦通常比其他谷物更耐受生物和非生物胁迫,它仍然可以被几种疾病感染,包括由顺孢菌引起的烫伤。本研究的目的是研究烫伤抗性的遗传结构,为了鉴定与烫伤抗性相关的遗传标记,可用于杂种黑麦的育种,并开发用于烫伤抗性基因组预测的模型。本研究使用了四个数据集,这些数据集记录了2年内和3个地点生长的251个杂交冬季黑麦品系的抗烫伤性。使用四个基因组模型来获得烫伤抗性的方差成分和遗传力。所有基因组模型都包括杂种亲本成分的加性遗传效应,其中三个模型包括加性上位和/或优势效应。所有模型均显示在0.31(SE0.05)至0.76(0.02)范围内的中等至高广义遗传力。没有非加性遗传效应的模型和具有优势效应的模型具有中等的狭义遗传力,范围为0.24(0.06)至0.55(0.08)。没有一个模型检测到显著的非加性基因组方差,可能是由于数据大小有限。进行了全基因组关联研究,以鉴定与杂交黑麦抗烫伤性相关的标记。在三个数据集中,该研究确定了总共12个标记与烫伤抗性显著相关。只有一个标记与影响烫伤抗性的主要数量性状基因座(QTL)相关。该标记解释了两个位置中11-12%的表型变异。在一个位置和其他两个位置之间发现了抗烫伤性的基因型与环境相互作用的证据,这表明在不同的环境中,抗烫伤性受到不同QTL的影响。根据基因组预测模型和GWAS的结果,烫伤抗性似乎是由许多次要QTL和一个主要QTL控制的数量性状,并受基因型与环境相互作用的影响。
    Rye (Secale cereale L.) is an important cereal crop used for food, beverages, and feed, especially in North-Eastern Europe. While rye is generally more tolerant to biotic and abiotic stresses than other cereals, it still can be infected by several diseases, including scald caused by Rhynchosporium secalis. The aims of this study were to investigate the genetic architecture of scald resistance, to identify genetic markers associated with scald resistance, which could be used in breeding of hybrid rye and to develop a model for genomic prediction for scald resistance. Four datasets with records of scald resistance on a population of 251 hybrid winter rye lines grown in 2 years and at 3 locations were used for this study. Four genomic models were used to obtain variance components and heritabilities of scald resistance. All genomic models included additive genetic effects of the parental components of the hybrids and three of the models included additive-by-additive epistasis and/or dominance effects. All models showed moderate to high broad sense heritabilities in the range of 0.31 (SE 0.05) to 0.76 (0.02). The model without non-additive genetic effects and the model with dominance effects had moderate narrow sense heritabilities ranging from 0.24 (0.06) to 0.55 (0.08). None of the models detected significant non-additive genomic variances, likely due to a limited data size. A genome wide association study was conducted to identify markers associated with scald resistance in hybrid winter rye. In three datasets, the study identified a total of twelve markers as being significantly associated with scald resistance. Only one marker was associated with a major quantitative trait locus (QTL) influencing scald resistance. This marker explained 11-12% of the phenotypic variance in two locations. Evidence of genotype-by-environment interactions was found for scald resistance between one location and the other two locations, which suggested that scald resistance was influenced by different QTLs in different environments. Based on the results of the genomic prediction models and GWAS, scald resistance seems to be a quantitative trait controlled by many minor QTL and one major QTL, and to be influenced by genotype-by-environment interactions.
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  • 文章类型: Journal Article
    在全麦面包生产中,烫伤和发酵有助于改善面团和面包的结构特征。本研究详细说明了发酵烫伤对黑麦和大麦面团以及面包结构形成的影响。使用扫描电子显微镜进行的微观结构分析揭示了烫伤发酵过程中的相分离。根据存储G\'和损耗G”模量,两种烫伤都表现出弹性而不是粘性。大麦烫伤的发酵增加了模量和复数粘度,而发酵黑麦烫伤没有观察到实质性变化。添加含有部分水解淀粉和一部分水溶性化合物的发酵烫伤对形成发酵4小时的面团组织良好的结构有积极贡献。发酵大大降低了面团的复数粘度和模量值,确认导致粘性部分增加的部分结构改变。发酵烫伤的面团比没有发酵烫伤的面团损失因子显著降低,表明机械加工能力增强。对于没有烫伤的面团,观察到结构最明显的弱化。向黑麦面团中添加黑麦烫伤促进了以相对较小的比容形成较少的孔。
    In wholemeal bread production, scalding and fermentation contribute to the improvement of the structural characteristics of the dough and bread. The influence of fermented scald on rye and barley dough and bread structure formation was specified in this study. The microstructural analysis performed using a scanning electron microscope revealed the separation of phases during the fermentation of scalds. According to the storage G\' and loss G″ moduli, both scalds exhibited elastic character over viscous. The fermentation of barley scald increased both moduli and complex viscosity, while no substantial changes were observed in the fermented rye scald. The addition of fermented scald containing partially hydrolyzed starch and a fraction of water-soluble compounds contributed positively to the formation of a well-organized structure of dough fermented for 4 h. Fermentation substantially reduced the dough\'s complex viscosity and moduli values, confirming the partial structure alteration leading to the viscous portion increase. The dough with fermented scald showed a significantly lower loss factor than the dough without fermented scald, indicating enhanced mechanical process ability. The most substantial weakening of the structure was observed for dough without scald. The addition of rye scald to the rye dough promoted the formation of fewer pores with relatively smaller specific volumes.
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  • 文章类型: Journal Article
    已注意到儿科年龄组特别容易遭受烧伤。烧伤是儿童受伤的第五大常见原因。尼日利亚人口非常年轻,中位年龄为18.1岁。烫伤是全球这个年龄段最常见的烧伤形式;然而,我们机构以前的报告发现,火焰是小儿年龄最常见的烧伤形式。13年前的最新报告仍然认为火焰是小儿烧伤的最常见原因。进行这项研究是为了确定儿童热烧伤的流行病学变化和结局。这是一项在2013年1月至2022年12月之间进行的回顾性研究。使用社会科学软件版本23的统计软件包分析数据。显著性设定为0.05的P值。二百六十五名儿童出现热烧伤,男女比例为1.3:1。63.4%发生在0-5岁儿童。烫伤(59.6%)是最常见的伤害原因。女性的大多数火焰伤害是由于液化石油气炉灶爆炸,而汽油爆炸是男性最常见的原因(P≤0.001)。烧伤深度逐年增加(P=.009)。大多数吸入性损伤发生在11-16岁的人群中(P=.006)。死亡率为10.2%,全身表面积烧伤(P≤0.001),烧伤深度(P≤.001),吸入性损伤(P≤0.001)与死亡率增加有关。烫伤现在是我们机构中最常见的热烧伤原因,死亡率显着降低。
    The pediatric age group has been noted to be particularly vulnerable to burn injuries. Burn is the fifth most common cause of childhood injuries. Nigeria has a very young population with a median age of 18.1 years. Scald is the most common form of burn injuries in this age group globally; however, previous reports from our institution found flame to be the most common form of burn in pediatric age. The most recent report from 13 years ago still maintained flame as the most common cause of pediatric burn injury. This study was carried out to determine the changes in epidemiology and outcome of pediatric thermal burn injury. This was a retrospective study carried out between January 2013 and December 2022. Data were analyzed using the statistical package for social sciences software version 23. The significance was set at a P-value of .05. Two hundred and sixty-five children presented with thermal burn with a male-to-female ratio of 1.3:1. 63.4% occurred in children 0-5 years. Scald (59.6%) was the most common cause of injury. Most flame injuries in females were due to liquified petroleum gas cookstove explosion, while petrol explosion was the most common cause in males (P ≤ .001). There is a yearly increase in burn depth (P = .009). Most inhalation injuries occurred in those aged 11-16 years (P = .006). Mortality rate was 10.2%, with total body surface area burned (P ≤ .001), burn depth (P ≤ .001), and inhalation injury (P ≤ .001) associated with increasing mortality. Scald is now the most common cause of thermal burn in our institution, with a remarkable reduction in mortality rate.
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  • 文章类型: Journal Article
    全球,热烧伤是烧伤的主要病因类型,占需要入院的烧伤的86%。火焰,烫伤,和接触烧伤是热烧伤的主要原因。社会的社会人口统计学特征的变化导致了烧伤流行病学的改变。了解烧伤流行病学的这种变化对于制定和执行适当的烧伤预防计划至关重要。我们试图建立目前的病因学趋势,性别分布,年龄,吸入性损伤的发生,燃烧表面积,烧伤深度,伊巴丹热烧伤的死亡率。这是一项在2013年1月至2022年12月之间进行的回顾性研究。热烧伤占烧伤的92%。男女比例为1.4:1。儿科年龄组有265名(45%)患者,和323名成年人(55%的患者)。火焰的比例,烫伤和接触烧伤为378(58%),203(32%),14(2%)。液化石油气(LPG)爆炸引起的火焰燃烧呈上升趋势,煤油的火焰燃烧减少(p<0.001)。一百九十(32%)患者有吸入性损伤。总死亡率为19%(N=114)。煤油火焰,38%(45名患者中有17名);液化石油气,32%(130例患者中有41例)是火焰损伤的最致命原因(p<0.043)。研究表明,液化石油气对热烧伤的病因的贡献越来越大。燃烧预防计划应针对LPG燃气灶和气瓶的安全使用。
    Worldwide, thermal burn is the leading etiological type of burn injury accounting for 86% of burn injuries requiring admissions. Flame, Scald, and contact burn are the leading causes of thermal burn. Changes in the sociodemographic characteristics of societies have led to alterations in the epidemiology of burn. An understanding of such changes in the epidemiology of burn is essential in formulating and executing adequate burn prevention programs. We sought to establish the current trend in the etiology, gender distribution, age, occurrence of inhalation injury, burn surface area, burn depth, and mortality rate of thermal burns at Ibadan. This was a retrospective study carried out between January 2013 and December 2022. Thermal burns constitute 92% of burn injuries. The male-to-female ratio was 1.4:1. There were 265 (45%) patients in the pediatric age group and 323 adults (55% of the patients). The proportion of flame, scald, and contact burns were 378 (58%), 203 (32%), and 14 (2%), respectively. Flame burns resulting from liquified petroleum gas (LPG) explosion show a rising trend, with a decline in flame burns from kerosene (P < .001). One hundred and ninety (32%) patients had inhalation injury. The overall mortality was 19% (N = 114). Kerosene flame, 38% (17 of 45 patients), and LPG, 32% (41 of 130 patients), were the most lethal causes of flame injuries (P < .043). The study shows the increasing contribution of LPG to the etiology of thermal burn injuries. Burn prevention programs should target safe use of LPG stoves and cylinders.
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  • 文章类型: Journal Article
    我们描述了向英国Pinderfields医院提交的监狱内袭击造成的故意烫伤的趋势和严重程度。数据是使用国际烧伤数据库的本地记录获得的。在2003年至2019年期间,该医院的整形外科和烧伤部门治疗了至少7所监狱的22例病例,在过去的4年里发生了20例。在大多数情况下使用沸水。其他物质包括沸水和糖的糖浆,和热脂肪。平均总身体表面积为2.8%,最常见的是脸,脖子,肩膀,和前胸。国家数据确定了267例病例,具有类似的上升趋势。由于在治疗期间需要增加安全和警察护送,这些伤害增加了我们烧伤服务的后勤和经济负担。同一监狱内的“山寨袭击”,在同一天的某个时候,人们担心这些伤害的发生率可能会增加。外联护理和远程医疗设施可以最大程度地减少管理期间的挑战。
    We describe the trends and severity of deliberate scald injuries from assaults within prisons presenting to Pinderfields Hospital in the United Kingdom. Data were obtained using local records of the International Burn Injury Database. Between 2003 and 2019, the hospital\'s Department of Plastic Surgery and Burns treated 22 cases from at least seven prisons, with 20 cases occurring in the last 4 years. Boiling water was used in most cases. Other substances included syrups of boiling water and sugar, and hot fat. Mean total body surface area was 2.8%, most commonly the face, neck, shoulders, and anterior chest. National data identified 267 cases with a similar rising trend. These injuries increase logistical and financial burdens on our burns service due to the need for added security and police escorts during treatment. \"Copycat attacks\" within same prisons, sometime on the same day, raise concerns that incidence of these injuries is likely to increase. Outreach nursing and telemedicine facilities may minimize the challenges during the management period.
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