sacrococcygeal

骶尾部
  • 文章类型: Case Reports
    异位胶质结节是一种罕见的先天性非肿瘤性病变,以异位脑组织为特征。据报道,偶尔会影响鼻子和面部等部位。报告介绍了一例罕见的骶尾部异位胶质结节。尽管畸胎瘤是该地区最常见的肿瘤,临床医生和放射科医师应将异位胶质结节作为鉴别诊断,尽管罕见和非特异性的影像学发现。组织病理学在诊断中起着至关重要的作用,它被胶质纤维酸性蛋白和S-100强烈染色。
    Heterotopic glial nodule is a rare congenital non-neoplastic lesion that is characterized by ectopic brain tissue. It has occasionally been reported to affect areas such as the nose and face. The report presents a rare case of sacrococcygeal heterotopic glial nodule. Although teratomas are the most common neoplasms in this region, clinicians and radiologists should consider heterotopic glial nodule as a differential diagnosis, despite rarity and nonspecific imaging findings. Histopathology plays a crucial role in diagnosis, which intensely stains with glial fibrillary acidic protein and S-100.
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  • 文章类型: Journal Article
    生殖细胞肿瘤(GCT)是一个复杂的,可能存在于性腺或性腺外部位的肿瘤的异质集合。它们由各种良性和恶性组织学组成,可以在整个身体的多个位置发生。治疗的重要组成部分是手术切除,虽然切除的关键部分是特定部位的,GCT切除的普遍目标包括在不侵犯肿瘤包膜的情况下完全切除肿瘤,同时保留周围器官的功能,将发病率降至最低,并评估区域传播。
    Germ cell tumors (GCT) are a complex, heterogeneous collection of tumors that may present in either gonadal or extragonadal sites. They consist of a variety of benign and malignant histologies that can occur at several locations throughout the body. An important component of treatment is surgical resection, and while the key components of resection are site specific, the universal goals of GCT resection include the complete resection of tumor without violating the tumor capsule, while preserving function of surrounding organs, minimizing morbidity, and assessing for regional spread.
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  • 文章类型: Case Reports
    成人骶尾部畸胎瘤(SCT)非常罕见,文献中只有少数病例。成人患病率在40000人中的1人和63000人中的1人之间变化。大多数SCT主要位于骨盆外(I型和II型),这在新生儿中更常见;然而,主要是骨盆内肿瘤(III型和IV型)在成年期更为典型。盆腔外畸胎瘤在成人中极为罕见。当SCT出现在成年人身上时,它表现为缓慢生长的肿瘤,没有症状,通常在变得足够大导致压迫症状后表现出来。SCT具有1-2%的恶性转化概率。在这里,我们报告了一个20岁的女性,他从小就被诊断为下背部肿胀,在过去2个月中体积增大;影像学检查显示盆腔外肿块。此案例描述了SCT的非典型场景,通过手术成功管理。组织病理学报告证实了诊断。
    Sacrococcygeal teratoma (SCT) in adults is very rare with only a few cases documented in the literature, adult prevalence varies between 1 in 40 000 and 1 in 63 000. Most SCTs are located either mainly extra-pelvic (types I and II), which are more commonly seen in neonates; however, mainly intra-pelvic tumors (types III and IV) are more typical in adulthood. Extra-pelvic teratomas are extremely rare in adults. When SCT manifests in an adult, it appears as a slow-growing tumor without symptoms and usually manifests after becoming large enough to cause compression symptoms. SCT has a 1-2% probability of malignant transformation. Herein, we report a 20-year-old female, who was diagnosed with lower back swelling since childhood that increased in size over the last 2 months; imaging revealed an extra-pelvic mass. This case describes an atypical scenario for SCT, which was successfully managed with surgery. The histopathology report confirmed the diagnosis.
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  • 文章类型: Case Reports
    骶尾部罕见的性腺外混合生殖细胞肿瘤,在畸胎瘤成分中有成熟的胸腺组织,这是一个罕见的发现,也是第一个报道的这种关联的案例。
    A rare extragonadal mixed germ cell tumor of the sacrococcygeal area presenting with mature thymic tissue in the teratomatous component, a rare finding and the first reported case of such an association.
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  • 文章类型: Case Reports
    骶尾部畸胎瘤(SCT),新生儿最常见的肿瘤性肿瘤之一,在成年人中很少见。这些畸胎瘤是生殖细胞肿瘤。这些肿瘤大多数是良性和囊性的,只有1-2%的人有恶性转化。这些肿瘤大多数是良性和囊性的,只有1-2%的人有恶性转化。女性发病率较高。通常,囊性畸胎瘤无症状,因此,诊断往往是在影像学检查中无意中做出的。大部分治疗是完全手术切除,和开放和腹腔镜手术已被证明是有效的。组织病理学检查可明确诊断。我们介绍了一名56岁女性患者的不寻常情况,该患者患有骶尾部畸胎瘤。
    Sacrococcygeal teratoma (SCT), one of the most common neoplastic tumors in newborns, is found very rarely in adults. These teratomas are germ cell tumours. Most of these tumors are benign and cystic in nature, with only 1-2% of them having a malignant transformation. Most of these tumors are benign and cystic in nature, with only 1-2% of them having malignant transformation. A higher incidence was seen in females. Typically, cystic teratomas are asymptomatic, and so the diagnosis was often made inadvertently during radiographic studies. The majority of treatment is complete surgical excision, and both open and laparoscopic procedures have been proven to be efficient. Histopathologic examination can confirm the diagnosis. We present this unusual instance of a 56-year-old female patient with a sacrococcygeal teratoma.
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  • 文章类型: Journal Article
    硬膜外麻醉通常作为围手术期镇痛的平衡麻醉的一部分进行。这项随机临床试验的主要目的是比较两种硬膜外入路对会阴疝手术犬的疗效。次要目的是比较运动阻滞。完整的ASA1和2只雄性狗,纳入体重≤25kg且既往未进行会阴疝手术的患者.在使用IM乙酰丙嗪0.02mg/kg和布托啡诺0.3mg/kg进行前用药后,全身麻醉用丙泊酚诱导,七氟醚维持在氧气中。狗被随机分配接受腰骶部(LS,n=30)或骶尾部(SC,n=26)在计算机断层扫描指导下硬膜外注射1%罗哌卡因(0.2mL/kg)。成功的镇痛定义为不需要术中抢救镇痛(芬太尼3μg/kgIV)。临床失败被定义为每只狗在手术结束时静脉内接受美洛昔康0.2mg/kg的芬太尼需要两次以上。格拉斯哥综合疼痛量表简表(GCPS-SF),触觉敏感性,在硬膜外注射后4,6,8和24h评估压痛阈值和运动阻滞.美沙酮(0.2mg/kg,如果GCPS-SF≥6/24分,则给予IV)。组间差异用Mann-WhitneyU检验分析,学生t检验或费舍尔精确检验,视情况而定。成功率在组间进行非劣效性评估。非劣效性幅度设定为-10%。LS组24只狗和SC组17只狗硬膜外镇痛成功(p=0.243),导致LS和SC组的成功率为80%和65%,分别。证实了SC组与LS组的非劣效性。在LS组中的两只狗和SC组中的一只狗中记录临床失败。组间GCPS-SF评分无显著差异,触觉敏感性,压力疼痛阈值,术后需要美沙酮,或马达封锁。两种硬膜外技术都是狗会阴疝修复的有价值的镇痛选择。
    Epidural anesthesia is commonly administered as part of balanced anesthesia for perioperative analgesia. The main goal of this randomized clinical trial was to compare the efficacy of two epidural approaches in dogs undergoing surgery for a perineal hernia. A secondary aim was to compare motor blockade. Intact ASA 1 and 2 male dogs, weighing ≤25 kg with no previous surgery for perineal hernia were enrolled. After premedication with IM acepromazine 0.02 mg/kg and butorphanol 0.3 mg/kg, general anesthesia was induced with propofol and maintained with sevoflurane in oxygen. Dogs were randomly allocated to receive either a lumbosacral (LS, n = 30) or a sacrococcygeal (SC, n = 26) epidural injection with ropivacaine 1% (0.2 mL/kg) under computed tomography guidance. Successful analgesia was defined as no need of intraoperative rescue analgesia (fentanyl 3 μg/kg IV). Clinical failure was defined as the need of more than two boluses of fentanyl/h each dog received meloxicam 0.2 mg/kg IV at the end of the surgery. The Glasgow Composite Pain Scale short form (GCPS-SF), tactile sensitivity, pressure pain thresholds and motor blockade were assessed at 4, 6, 8, and 24 h after the epidural injection. Methadone (0.2 mg/kg, IV) was administered if the GCPS-SF was ≥6/24 points. Differences between groups were analyzed with the Mann-Whitney U test, Student\'s t-test or Fisher\'s Exact test, as appropriate. Success rate was assessed for non-inferiority between groups. The non-inferiority margin was set at -10%. Epidural analgesia was successful in 24 dogs in group LS and 17 dogs in group SC (p = 0.243), resulting in success rates of 80 and 65% in LS and SC groups, respectively. The non-inferiority of group SC versus group LS was confirmed. Clinical failure was recorded in two dogs in group LS and one dog in group SC. No significant differences between groups were detected in the GCPS-SF score, tactile sensitivity, pressure pain thresholds, need of post-operative methadone, or motor blockade. Both epidural techniques are valuable analgesic options for perineal hernia repair in dogs.
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  • 文章类型: Case Reports
    We describe the unusual case of a female patient with a history of two mature teratomas non-correlated in terms of location and occurrence. A 12-year-old girl presented at our consultation as a result of a growing tumor in the hypogastric region, with no further clinical signs. She had undergone surgery neonatally due to a mature cystic sacrococcygeal teratoma, which was fully removed. No clinical sequelae were noted and no additional treatment was required over a 10-year follow-up. Radiological examination showed a large 20 × 12 × 18 cm cystic mass extending from the pelvic region to the lower hemiabdomen, associated with two similar small formations adjacent to the right ovary. Tumor markers were negative, and a laparoscopic right salpingoophorectomy was carried out, with an excellent postoperative progression. Pathological examination revealed it was, again, a mature cystic teratoma. The genetic study ruled out causation in this respect.
    Describimos el inusual caso de una paciente con antecedente de dos teratomas maduros no relacionados en cuanto a su localización y debut. Una niña de 12 años consultó por la aparición de una tumoración en la región hipogástrica de crecimiento progresivo sin otra clínica asociada. Había sido intervenida por un teratoma quístico maduro sacrococcígeo en el periodo neonatal con su extirpación completa y, ausencia secuelas clínicas y tratamiento adicional durante diez años de seguimiento posterior. Los exámenes radiológicos mostraron una gran masa quística de 20 × 12 × 18 cm que se extendía entre la región pélvica y el hemiabdomen inferior, acompañada por otras dos pequeñas formaciones similares adyacentes al ovario derecho. Los marcadores tumorales resultaron negativos y se llevó a cabo una salpingooforectomía derecha laparoscópica con una excelente evolución postoperatoria. El examen histopatológico, de nuevo, informó la lesión como teratoma quístico maduro. El estudio genético descartó una posible causalidad en este ámbito.
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  • 文章类型: Case Reports
    我们介绍了一个直肠后间隙支气管囊肿的病例,该病例通过独特的骶尾部手术方法成功治疗。从而避免进入腹部。本报告旨在通过我们的技术增强文献,并帮助科学界治疗未来的直肠后支气管囊肿病例。一名19岁的男子因睾丸疼痛而无法使用非处方镇痛药而住院。在骨盆磁共振成像中发现了s前区域的囊肿病变。我们确定囊肿的上皮为呼吸型,含纤毛假复层柱状上皮,有鳞状上皮化生灶。支气管囊肿从原始前肠异常,它在直肠后部位的位置很少见。这种类型的病变患者通常无症状,在成像检查期间,发现通常是偶然的。建议切除,腹膜后支气管囊肿切除术后预后良好。我们对该主题的描述对于帮助将来的类似案件至关重要。
    We present a case of a bronchogenic cyst in the retrorectal space that was successfully treated with a unique sacrococcygeal surgical approach, thus avoiding abdominal access. This report aims to enhance the literature with our technique and to help the scientific community in treating future retrorectal bronchogenic cyst cases. A 19-year-old man presented to the hospital with testicular pain refractory to over-the-counter analgesics. A cyst lesion in the presacral region was found during pelvic magnetic resonance imaging. We identified the cyst\'s epithelium as the respiratory type, containing ciliated pseudostratified columnar epithelium with foci of squamous metaplasia. The bronchogenic cyst is abnormal from the primitive foregut, and its location on the retrorectal site is rare. Patients with this type of lesion are usually asymptomatic, and discovery is commonly incidental during imaging exams. Excision is advised, and the prognosis is good after retroperitoneal bronchogenic cyst removal. Our description of the topic is essential to assist future similar cases.
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  • 文章类型: Case Reports
    骶尾部卵黄囊瘤(YST)是一种罕见的性腺外恶性生殖细胞肿瘤(GCT),仅在生命的头两年内发生。一个两岁的女孩左臀部有一个巨大的肿块,它继续增长,三个月内变得非常大,阻碍了她走路。体格检查发现骶尾部肿块直径15厘米。多层CT显示腔内下腔静脉肿块延伸到骨盆腔并尾骨骨破坏,肺转移,和多发性肝转移。实验室数据显示α-feto-蛋白(AFP)的肿瘤标志物值升高,乳酸脱氢酶(LDH),还有Ca-125.对涂片样本进行细针穿刺活检后的细胞病理学检查显示,细胞肿瘤具有假性腺,微囊,和坚实的图案。细胞病理学未显示病因学结果。细胞块的免疫细胞化学(IHC)检查显示抗AFP抗体的阳性结果。该患者被诊断并接受了骶尾骨YST的化疗。第4个月的临床随访显示肿瘤缩小至4cm。四个月后的实验室随访数据显示显着改善。不幸的是,由于肺和肝转移,患者在第七个化疗周期死亡。
    Sacrococcygeal yolk sac tumor (YST) is an infrequent extra-gonadal malignant germ cell tumor (GCT) that occurs exclusively within the first two years of life. A two-year-old girl came with a massive mass on her left buttock, which continued to grow, and within three months had become extremely large and hindered her from walking. Physical examination revealed a sacrococcygeal mass of 15 cm in diameter. Multislice CT showed an intraluminal inferior cava vein mass extending into the pelvic cavity with coccygeal osseous destruction, pulmonary metastasis, and multiple hepatic metastases. Laboratory data revealed elevated tumor marker values for alpha-feto-protein (AFP), lactate dehydrogenase (LDH), and Ca-125. Cytopathology following fine needle aspiration biopsy evaluation of the smear sample revealed a cellular tumor with pseudo glandular, microcystic, and solid patterns. The cytopathology did not show pathognomic findings. An immunocytochemistry (IHC) examination of the cell block showed a positive result for anti-AFP antibody. The patient was diagnosed and treated with chemotherapy for a sacrococcygeal YST. Clinical follow-up on the fourth month showed that the tumor had shrunk to 4 cm in size. Laboratory follow-up data after four months showed significant improvement. Unfortunately, the patient passed away on the seventh cycle of chemotherapy due to lung and hepatic metastases.
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  • 文章类型: Journal Article
    背景:人皮病(PD)是一种常见且使人衰弱的炎症性疾病,对生活质量有重大影响。与传统切除相比,微创技术(MIT)已显示出有希望的结果。在这里,我们介绍了两种MIT技术的比较-正弦切除术(SE)和挖坑加激光消融(PPL)。
    方法:回顾性分析2018年8月至2020年8月在我们中心接受PPL和SE治疗的所有儿童PD病例。
    结果:纳入了106名患者,年龄中位数为16岁(IQR15-16)。PPL是36例患者(34%)的首选手术,其余患者接受SE(66%)。SE组的中位愈合时间(20天)明显较低,与PPL(30天)相比(p=0.002)。PPL组早期愈合失败发生率更高(p=0.003)。两组之间的复发率相似-PPL17%与SE16%(p=0.89)。总并发症发生率为9%,PPL患者明显更高(p=0.03)。
    结论:MIT技术是PD治疗的有希望的解决方案。虽然同样容易和快速执行,SE技术显示愈合情况较好,并发症发生率较低,但复发率无明显差异。
    Pilonidal disease (PD) is a common and debilitating inflammatory condition with significant impact on quality of life. Minimally invasive techniques (MIT) have shown promising results comparing to traditional excision. Herein we present a comparison of two MIT techniques -sinusectomy (SE) and pit-picking plus laser ablation (PPL).
    All cases of paediatric PD treated by PPL and SE at our center between August 2018 and August 2020 were retrospectively reviewed.
    One-hundred and six patients were included, with a median age of 16 years (IQR 15-16). PPL was the procedure of choice in 36 patients (34%) and the remaining underwent SE (66%). Median healing time was significantly lower in SE group (20 days), comparing to PPL (30 days) (p = 0.002). Early healing failure occurred more frequently in the PPL group (p = 0.003). Recurrence rate was similar between groups - PPL 17% versus SE 16% (p = 0.89). Overall complication rate was 9% and was significantly higher in PPL (p = 0.03).
    MIT techniques are promising solutions in PD treatment. Although similarly easy and fast to perform, SE technique showed better healing profile and lower complication rate but no significant difference on recurrence rates was observed.
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