背景:近7010万人感染了被称为2019年冠状病毒病(COVID-19)的大流行性病毒性疾病,它最初是在中国发现的,是由一种被称为严重急性呼吸道综合症冠状病毒2(SARS-CoV-2)的新型冠状病毒引起的。这种疾病是造成600万人死亡的原因。印度在病例总数中排名第三。这项研究的目的是根据几个标准对COVID-19患者进行分类,并确定哪些临床,血液学,放射学指标在他们的护理中最为重要。
方法:对70例有症状的患者进行了横断面分析研究,这些患者的COVID-19逆转录聚合酶链反应(RT-PCR)检测呈阳性,并在Saveetha医学院和金奈医院住院,泰米尔纳德邦,印度,在研究期间。在将患者分为三类之一时,考虑了合并症和氧气依赖。最初的症状,以及血液学(白细胞介素-6(IL-6),红细胞沉降率(ESR),C反应蛋白(CRP),D-二聚体,血清铁蛋白,和总细胞计数)和放射学(胸部的X射线和计算机断层扫描(CT))特征,在不同的群体中进行了采集和分析。
结果:根据我们的研究,发烧的症状是最常见的,占全部病例的84.3%。其次是呼吸困难(55.7%),肌痛(31.4%),干咳(27.1%),喉咙痛(24.3%),咳嗽咳痰(20%),稀便(12.9%),味觉损失(12.9%),和气味(11.4%)。虽然D-二聚体有很大的变异,C类值最高,ESR和CRP仅有少量变化.胸部的X线和CT扫描显示两组之间有很大差异,CT检查结果如COVID-19报告和数据系统(CO-RADS)和CT严重程度评分,合并,疯狂的铺路图案,和血管扩张显示出两组之间的广泛差异。
结论:为了使治疗更容易,并更关注使用D-二聚体的放射学特征,治疗医生需要将COVID-19患者分为几组。需要氧气支持的患者包括在这一类别中。
BACKGROUND: Nearly 70.1 million individuals have been infected by the pandemic viral disease known as coronavirus disease 2019 (COVID-19), which was first discovered in China and is caused by a novel coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2). This disease is responsible for the deaths of 6 million people. India ranks third in the total number of cases. The purpose of this study was to classify COVID-19 patients according to several criteria and to determine which clinical, hematological, and radiological indicators were most important in their care.
METHODS: An analytical cross-sectional study was conducted on a total of 70 symptomatic patients who tested positive for COVID-19 reverse transcription polymerase chain reaction (RT-PCR) and were hospitalized at the Saveetha Medical College and Hospital in Chennai, Tamil Nadu, India, for the duration of the study. Comorbidities and oxygen reliance were taken into consideration while classifying patients into one of three categories. Initial symptoms, as well as hematological (interleukin-6 (IL-6), erythrocyte sedimentation rate (ESR), c-reactive protein (CRP), D-dimer, serum ferritin, and total cell counts) and radiographic (X-ray and computed tomography (CT) of the thorax) characteristics, were taken and analyzed among the different groups.
RESULTS: According to our research, the symptom of fever was the most common, accounting for 84.3% of all cases. This was followed by breathlessness (55.7%), myalgia (31.4%), dry cough (27.1%), sore throat (24.3%), cough with expectoration (20%), loose stools (12.9%), loss of taste (12.9%), and smell (11.4%). Although there was a large amount of variation in D-dimer, with Category C having the highest values, there was only a minor amount of variation in ESR and CRP. The X-ray and CT scans of the chest showed substantial differences between the groups, with CT findings such as COVID-19 Reporting and Data System (CO-RADS) and CT severity score, consolidation, crazy paving pattern, and vascular dilatation showing a wide range of differences between the groups.
CONCLUSIONS: To facilitate easier treatment and place more attention on radiological characteristics using D-dimer, treating physicians are required to categorize COVID-19 patients into several groups. Patients who need oxygen support were included in this category.