rotary files

旋转文件
  • 文章类型: Journal Article
    这项体外研究的目的是使用动态测试装置比较三种不同的根管镍钛旋转仪器的循环疲劳抗性。
    每个ProTaperGold(PG)有十个文件,Hyflex电火花加工(HEDM),在具有5mm的曲率半径的60°曲率下,在定制制造的动态循环疲劳测试装置中测试TruNatomy(TN)。计算每个仪器的骨折周期数(NCF),并通过Kruskal-Wallis测试比较三个连续组,并使用Dunnposthoc测试进行成对比较。
    HEDM的耐循环疲劳性最高,其次是TN。PG是三者中最低的。
    在目前体外结果的限制范围内,可以得出结论,HEDM文件似乎适合于在骨折前形成更多周期的复杂运河。
    UNASSIGNED: The aim of this in vitro study was to compare the cyclic fatigue resistance of three different endodontic nickel-titanium rotary instruments using a dynamic testing device.
    UNASSIGNED: Ten files each of ProTaper Gold (PG), Hyflex Electro-discharge Machining (HEDM), and TruNatomy (TN) were tested in a custom-fabricated dynamic cyclic fatigue testing device at 60° curvature having a radius of curvature of 5 mm. The number of cycles to the fracture (NCF) of each instrument was calculated and three continuous groups were compared by the Kruskal-Wallis test and Dunn post hoc test was used for pairwise comparison.
    UNASSIGNED: Cyclic fatigue resistance of HEDM was the highest, followed by TN. PG had the lowest among the three.
    UNASSIGNED: Within the limitations of the present in vitro results, it can be concluded that HEDM files appeared to be suitable for shaping complex canals with the greater number of cycles before it fractures.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    在牙髓文件系统的物理和机械特征方面的最新创新已经减少了新型牙髓文件系统中应力产生和骨折风险的前景。
    这项研究的目的是通过有限元分析在根管壁的三个不同水平上比较评估最近引入的具有不同特征和冶金性的牙髓旋转文件的应力分布。
    在通过扫描电子显微镜检查任何表面畸形后,在本实验中使用了40个牙髓文件。根据他们的冶金和设计,扫描的文件分为四组,每个有10个样本:A-2Shape组文件,B-F360组,C-One曲线,和D组-真理。要评估这些文件的力学行为,使用ANSYS®15Workbench有限元软件对这些器械的计算机辅助模型在模拟根管牙本质壁上产生的应力进行了数值分析。
    使用单向方差分析通过事后Tukey分析评估所有原始数据,夏皮罗-威尔克测试,和Levene的测试。F360文件在牙本质壁上施加了最大应力,而TruNatomy文件在牙本质壁的所有不同层次上施加的压力最小。
    四组之间产生的压力没有统计学上的显着差异。因此,可以得出的结论是,在旋转文件的设计和冶金的改进有可能减少应力在管道成形和在临床使用过程中器械断裂的风险。
    UNASSIGNED: Recent innovations in the physical and mechanical features of endodontic file systems have diminished the prospect of stress generation and fracture risk in novel endodontic files.
    UNASSIGNED: The purpose of this research was to comparatively evaluate the stress distribution of recently introduced endodontic rotary files with distinct features and metallurgy at three different levels of the root canal wall by finite element analysis.
    UNASSIGNED: Forty endodontic files were used in this experiment after being inspected through a scanning electron microscope for any surface deformities. Based on their metallurgy and design, the scanned files were divided into four groups, each with 10 samples: Group A-2Shape files, Group B-F360, Group C-One Curve, and Group D-TruNatomy. To assess the mechanical behavior of these files, the stress produced by computer-aided models of these instruments on the dentinal wall of a simulated root canal was numerically analyzed using ANSYS® 15 Workbench finite element software.
    UNASSIGNED: A one-way ANOVA was used to assess all the raw data with post hoc Tukey analysis, the Shapiro-Wilk test, and Levene\'s test. F360 files exerted the maximum stress on the dentinal wall, while TruNatomy files exerted the least stress at all the distinct levels of dentinal walls.
    UNASSIGNED: There was no statistically significant variation in the stress generated between the four groups. Therefore, it can be concluded that improvements in rotary file design and metallurgy have the potential to reduce the stress during canal shaping and the risk of instrument breakage during clinical use.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    龋齿确实是牙齿脱落的最大原因,特别是在初级牙列中。在龋齿牙髓受累的乳牙中,主张以牙髓切除术(仅去除冠状牙髓)或牙髓切除术(去除冠状牙髓和神经根牙髓)的形式进行牙髓干预。牙髓切除术既费力又费时,特别是当使用传统的手牙髓文件来塑造根管。在儿科牙科,事实证明,电动镍钛(Ni-Ti)旋转仪器在提高牙髓切除术质量方面具有重要意义。在原发性牙列中,然而,这些文件可能会留下一半以上的根管不被仪器改变,就像它们在恒牙中一样。XP-endo®Shaper是一个革命性的热依赖牙髓文件,使用不对称旋转运动来解决根管空间的最大面积,导致解剖根管器械。该病例系列描述了这种新颖的XP-endo®Shaper文件在患有不可逆牙髓炎的原发性磨牙的解剖根管器械中的使用。目的是证明这种尖端牙髓治疗方法的功效和优点。通过提供实用的说明如何利用适应性仪器来成功治疗患者,此病例系列可以为其他牙髓专家提供信息资源。总之,XP-endoShaper®在牙髓切除术中的使用速度更快,并且仪器受到运河原始形状的限制,尽管需要进一步的研究才能充分利用这些发现。
    Dental caries is indeed the biggest cause of tooth loss, particularly in the primary dentition. In primary teeth with carious pulp involvements, endodontic intervention in the form of pulpotomy (removal of only the coronal pulp) or pulpectomy (removal of coronal and radicular pulp) is advocated. Pulpectomy can be laborious and time-consuming, especially when using traditional hand endodontic files to shape root canals. In paediatric dentistry, motorised nickel-titanium (Ni-Ti) rotary instrumentation has proved significant in enhancing the quality of pulpectomy. In primary dentition, however, these files may leave more than half of the root canals unaltered by instrumentation, just as they do in permanent dentition. The XP-endo® Shaper is a revolutionary heat-dependent endodontic file that uses an asymmetrical rotating motion to address the maximum area of the root canal space, resulting in anatomic root canal instrumentation. The case series describes the use of this novel XP-endo® Shaper file for anatomic root canal instrumentation in primary molars with irreversible pulpitis. The purpose is to demonstrate the efficacy and advantages of this cutting-edge endodontic treatment method. This case series can be an informative resource for other endodontic specialists by providing a practical illustration of how adaptable instrumentation can be utilised to successfully treat a patient. In conclusion, The use of the XP-endo Shaper® for pulpectomy demonstrated faster and instrumentation that was confined with the original shape of the canals, although further research is required to fully utilise these findings.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    在使用文件系统XPendoShaper进行仪器检查后,评估下颌第一磨牙弯曲近中颊管的运河运输和对中能力,自调整文件(SAF),HyflexEDM,ProTaperNEXT,WaveOneGold,和K文件与锥束计算机断层扫描(CBCT)的帮助。
    评估了90个最近提取的下颌第一磨牙,其近颊根具有25-30度管曲率。术前CBCT扫描后,牙齿被随机分配到六个实验组15。在使用XPendoShaper进行准备之后,SAF,HyflexEDM,ProTaperNext,WaveOneGold,和K文件,使用与术前扫描相同的参数进行仪器后扫描.在3毫米处,6mm,离顶点9毫米,对样品进行运河运输和定心比评估。
    与除SAF外的其他组相比,XPendoShaper的根尖运输最少,结果具有统计学意义。K档案显示根尖向根管侧壁的最高运输。XPendoShaper在保持根管中部和根尖三分之一的定心能力方面更好,SAF在保持冠状三分之一的定心能力方面更好。
    在根管准备中,与其他文件系统相比,XPendoShaper的顶端运输最少,对中能力更好。K文件显示最高的运输。
    UNASSIGNED: To assess the canal transportation and centering ability in the mandibular first molars\' curved mesiobuccal canals after instrumentation with file systems XP endo Shaper, self-adjusting File (SAF), Hyflex EDM, Pro Taper NEXT, WaveOne Gold, and K files with the help of Cone-Beam Computed Tomography (CBCT).
    UNASSIGNED: Ninety recently extracted mandibular first molars with mesiobuccal roots that had a 25-30 degree canal curvature were assessed. Following preoperative CBCT scans, teeth were allocated randomly to six experimental groups of fifteen. After preparation with XP endo Shaper, SAF, Hyflex EDM, Pro Taper Next, WaveOne Gold, and K files, post-instrumentation scans were taken using same parameters as pre operative scans. At 3 mm, 6 mm, and 9 mm from the apex, samples were assessed for canal transportation and centering ratio.
    UNASSIGNED: Apical transportation was least for XP endo Shaper as compared to other groups except SAF and the results were statistically significant. K file showed the highest apical transportation toward the lateral wall of the root canal. XP endo Shaper was better in maintaining centering ability of middle and apical third of canal and SAF was better in maintaining centering ability of coronal third.
    UNASSIGNED: In root canal preparation, least apical transportation and better centering ability with XP endo Shaper than other file systems compared. K file showed the highest transportation.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    牙髓准备在很大程度上取决于在根管准备中使用的文件系统。从顶点挤出的管内碎片的量可能受文件系统的影响。因此,本体外研究评估了两种文件系统在不同工作长度下挤出的碎片量。
    收集了40条第一磨牙的人类近颊管,这些管因各种原因而被提取。他们被平均分为四组Reciproc(全长),Reciproc(短1mm),WaveOneGold(全长),和WaveOne黄金(短1毫米)。遵循常规的冠下技术进行间歇灌溉的运河准备。将挤出的碎片称重并比较其显著性。
    挤出的碎片的量在所有四组中重量相似,没有显著变化。Reciproc挤出的材料少于WaveOneGold。
    无论文件的物理属性如何,文件系统似乎都不会影响碎片挤出。有必要在临床设置中进行进一步的研究。
    UNASSIGNED: The endodontic preparation depends largely on the file systems that are used in the canal preparations. The amount of the intracanal debris that is extruded from the apex may be influenced by the file systems. Hence, the present in vitro study evaluated the amount the debris that is extruded for the two file systems at different working lengths.
    UNASSIGNED: Forty human mesiobuccal canals of the first molars were collected that were extracted for various causes. They were equally divided to four groups of Reciproc (full length), Reciproc (short by 1 mm), WaveOne Gold (full length), and WaveOne Gold (short by 1 mm). Routine crown-down technique was followed for the canal preparation with the intermittent irrigation. The extruded debris was weighed and compared for the significance.
    UNASSIGNED: The amount of the debris that was extruded weighed similarly in all the four groups with no significant variations. The Reciproc extruded lesser material than the WaveOne Gold.
    UNASSIGNED: The file systems seem not to affect the debris extrusion irrespective of the files\' physical properties. Further studies in a clinical setup are warranted.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:在根管治疗中使用不同原理的文件系统正变得越来越普遍。这项研究的目的是评估使用常规手文件后,根部冠状区域的剩余牙本质体积和准备效率,WaveOneGold;与往复运动一起工作,和TruNatomy;在下颌磨牙的根管治疗中与旋转运动一起使用。
    方法:使用所有下颌恒磨牙管(n=36)。每组(n=12)的根管都用常规的手文件准备,WaveOneGold,和TruNatomy。评估三维图像的牙根冠状2毫米区域的剩余牙本质体积以及整个根管空间的体积变化。
    结果:在准备前后的平均差异方面,两组之间没有统计学上的显着差异(P>0.05)。在WaveOneGold组中观察到的平均差异最多,在根和整个根管体积的冠状2毫米区域中,TruNatomy组中观察到的平均差异最小,但差异均不显著(P>.05,P>.05)。
    结论:常规手文件,WaveOneGold与往复运动一起工作,和TruNatomy用旋转运动工作,这是研究中使用的文件系统,在牙根冠状2毫米区域的剩余牙本质体积和下颌磨牙整个根管空间的准备效率方面,彼此并不优越。
    BACKGROUND: The use of file systems that work with different principles in root canal treatment is becoming widespread. The aim of this study was to evaluate the remaining dentine volume in the coronal region of the root and preparation efficiency after the use of conventional hand files, WaveOne Gold; which works with reciprocating motion, and TruNatomy; which works with rotational motion in the root canal treatment of mandibular molar teeth.
    METHODS: All canals of permanent mandibular molars (n = 36) were used. Root canals in each group (n = 12) were prepared with conventional hand files, WaveOne Gold, and TruNatomy. The three-dimensional images were evaluated for remaining dentine volume in the coronal two-millimeter region of the root and change in volume of the entire root canal space.
    RESULTS: There was no statistically significant difference between the groups in terms of mean differences pre and postpreparation (P > .05). The mean differences after preparation were observed the most in the WaveOne Gold group and the least in the TruNatomy group in the coronal two-millimeter region of the root and entire canal volume, but the differences were not significant (P > .05, P > .05, respectively).
    CONCLUSIONS: Conventional hand files, WaveOne Gold working with reciprocating motion, and TruNatomy working with rotational motion, which are the file systems used in the study, are not superior to each other in terms of remaining dentin volume in the coronal two-millimeter region of the root and preparation efficiency in the entire root canal space in mandibular molars.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    本研究旨在评估使用小儿旋转(EndoArtPedoKitBlue,EasyInSmileX-Baby和DencoKids),旋转(ProTaperNext)和往复(WaveOneGold)文件系统,通过初级磨牙的微生物分析。选择75颗下颌初级第二磨牙,分为5个器械组和1个阴性对照组。孵化后,使用五个根来确认根管上的生物膜形成。仪表之前和之后,收集细菌样本。通过使用Kruskall-Wallis和Dunn事后检验以0.05的显著性水平对细菌载量减少进行统计学分析。DencoKids和EndoArtPedoKitBlue比EasyInSmileX-Baby系统促进了更高的细菌减少。ProTaperNext旋转文件系统和其他组之间的细菌减少没有差异。在单文件技术中,DencoKids旋转系统的仪器显示出比WaveOneGold更显著的细菌负荷减少(p<0.05)。研究中使用的所有系统都减少了乳牙根管的细菌数量。需要进一步的研究来产生更多关于儿科旋转文件系统在诊所中使用的信息。
    This study aimed to evaluate the efficacy of intracanal Enterococcus faecalis reduction using pediatric rotary (EndoArt Pedo Kit Blue, EasyInSmile X-Baby and Denco Kids), rotary (ProTaper Next) and reciprocating (WaveOne Gold) file systems through microbiological analyses in primary molars. Seventy-five mandibular primary second molars were selected and divided into five instrumentation groups and a negative control group. After incubation, five roots were used to confirm biofilm formation on the root canals. Before and after instrumentation, bacterial samples were collected. The bacterial load reduction was statistically analyzed by using Kruskall-Wallis and Dunn post hoc tests at a significance level of 0.05. Denco Kids and EndoArt Pedo Kit Blue promoted higher bacterial reduction than EasyInSmile X-Baby systems. There was no difference in bacterial reduction between ProTaper Next rotary file systems and other groups. Among the single-file techniques, instrumentation with the Denco Kids rotary system showed a more significant bacterial load reduction than WaveOne Gold (p < 0.05). All systems used in the study reduced bacterial counts from root canals in primary teeth. Further studies are required to generate more information about the use of pediatric rotary file systems in clinics.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    未经评估:本研究的目的是比较评估Kedo-SG蓝色旋转文件的功效,手动K文件,和手动H文件,以消除原磨牙的根管微生物区系。
    UNASSIGNED:研究中纳入了需要进行牙髓切除术的45个原发性磨牙。根据仪器的类型,牙齿被随机分配到三组中的一组:A组:Kedo-SG蓝色旋转文件,B组:手动H文件,和C组:手动K文件。无菌吸收纸点用于样品收集并储存在含有盐水作为运输介质的无菌Eppendorf管中。在巯基乙酸盐琼脂和血琼脂培养基上进行培养,以培养厌氧和需氧微生物,分别,并使用数字菌落计数器记录为菌落形成单位(CFU)。进行Wilcoxon符号秩检验和单向方差分析(ANOVA)检验进行统计分析。
    UNASSIGNED:Postinstrumentation,A组记录到需氧和厌氧微生物计数减少93-96%。B组减少87-91%,C组减少90-91%.
    UNASSIGNED:Kedo-SG蓝色旋转文件显示,与手动仪器相比,根管中的微生物减少更好。然而,手动和旋转仪器在减少原始根管微生物方面没有显着差异。
    未经授权:LakshmananL,JeevanandanG.手动K文件生物力学制备后根管的微生物评估,手动H文件,和Kedo-SG蓝色旋转文件:体内研究。IntJClinPediatrDent2022;15(6):687-690。
    UNASSIGNED: The purpose of the present study was to comparatively evaluate the efficacy of Kedo-SG blue rotary files, manual K-files, and manual H-files in eliminating the root canal microflora of primary molars.
    UNASSIGNED: Forty-five primary molars requiring pulpectomy were included in the study. Based on type of instrumentation, the teeth were randomly assigned to one of the three groups: group A: Kedo-SG blue rotary files, group B: manual H-files, and group C: manual K-files. Sterile absorbent paper points were used for sample collection and stored in sterile Eppendorf tubes containing saline as transport medium. Culturing was done on thioglycolate agar and blood agar media for the cultivation of anaerobic and aerobic microbes, respectively, and recorded as colony-forming units (CFU) using digital colony counter. Wilcoxon signed-rank test and one-way analysis of variance (ANOVA) test were performed for statistical analysis.
    UNASSIGNED: Postinstrumentation, 93-96% reduction of aerobic and anaerobic microbial count was recorded in group A. Whereas, it was 87-91% reduction in group B and 90-91% reduction in group C. No statistically significant difference was noted between the three groups.
    UNASSIGNED: Kedo-SG blue rotary files showed a better reduction of microbes in root canals when compared to manual instrumentation. However, there was no significant difference between manual and rotary instrumentation in microbial reduction of primary root canals.
    UNASSIGNED: Lakshmanan L, Jeevanandan G. Microbial Evaluation of Root Canals after Biomechanical Preparation with Manual K-files, Manual H-files, and Kedo-SG Blue Rotary Files: An In Vivo Study. Int J Clin Pediatr Dent 2022;15(6):687-690.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    对于临床医生来说,提供为牙髓治疗的牙齿提供耐久性的修复治疗是非常重要的。创伤,咬合过早接触,和牙齿的特征是一些可能导致根管治疗牙齿的垂直根部骨折(VRF)的问题。这项3-D研究的目的是比较使用各种带有不同旋转系统的立柱设计时下颌前磨牙的应力分布。六颗下颌前磨牙用以下工具进行了测量:ProTaper下一步,WaveOne(WO),Reciproc(R),倒数蓝(RB),F6-Skytaper,和TF-自适应。使用锥形束计算机断层扫描(CBCT)扫描牙齿,并将图像转移到CatiaV5R25软件中。以立体光刻(STL)格式记录数据。使用了四种不同的员额系统,用金属制造,纤维,氧化锆,和钛,分别。Dentin,古塔,post,核心,和冠模型被添加到实体模型中。ANSYSV17.2有限元分析(FEA)软件用于确定每个组件上的应力分布。创建了有限分析模型,该模型可以计算250-N载荷在45°角度和与根部垂直的应力分布。在根部倾斜载荷下,最大主应力和vonMises值较高。F6-Skytaper和WO系统显示出比其他系统更低的应力。TF-Adaptive仪器显示出比其他模型更高的应力分布。纤维和钛柱显示出比其他更低的应力。F6-Skytaper,R,发现RB仪器在牙冠的位移方面最有效,导致最低的应力值。纤维和钛柱显示出比其他柱系统更好的结果,而使用F6-Skytaper和WO仪器的根管不太可能导致根部骨折。
    It is very important for clinicians to provide restorative treatments that provide durability for endodontically treated teeth. Trauma, occlusal premature contact, and features of teeth are some of the issues that can cause vertical root fractures (VRFs) in root canal-treated teeth. The aim of this 3-D study was to compare stress distribution on mandibular premolar teeth when using a variety of post designs instrumented with different rotary systems. Six mandibular premolar teeth were instrumented with the following tools: ProTaper Next, WaveOne (WO), Reciproc (R), ReciprocBlue (RB), F6-Skytaper, and TF-Adaptive. Teeth were scanned using cone beam computed tomography (CBCT) and the images were transferred to the Catia V5R25 software. Data were recorded in a stereolithography (STL) format. Four different post systems were used, fabricated from metal, fiber, zirconia, and titanium, respectively. Dentin, gutta, post, core, and crown models were added to the solid model. ANSYS V17.2 finite element analysis (FEA) software was used to determine stress distribution on each assembly. Finite analysis models were created that allowed for the calculation of stress distribution of 250-N loading at a 45° angle and vertical in relation to the roots. The maximum principal stress and von Mises values were higher under oblique loading on the roots. The F6-Skytaper and WO systems showed lower stress than other systems. The TF-Adaptive instrument showed higher stress distribution than the other models. Fiber and titanium posts showed lower stress than others. The F6-Skytaper, R, and RB instruments were found to be most effective in terms of displacement of the crown, resulting in the lowest stress values. Fiber and titanium posts showed better results than other post systems, while root canals instrumented with the F6-Skytaper and WO instruments were less likely to result in root fractures.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    UNASSIGNED:这项研究的目的是比较已用于牙髓学的镍钛(Ni-Ti)合金与钛钼(Ti-Mo)和钛-铌(Ti-Nb)合金的机械和结构性能,以确定是否可以在牙髓文件的制造中建议使用这些合金。
    UNASSIGNED:使用由不同合金制成的正畸线。前面提到的合金通过能量色散X射线光谱(EDX)进行了表征,X射线衍射(XRD)和扭转试验。在曲率为86°至375rpm的模拟运河上进行循环疲劳测试。通过扫描电子显微镜(SEM)观察了金属丝的断裂表面。使用Kruskal-Wallis检验和UMannWhitney检验来确定组间循环疲劳的显着差异。
    UNASSIGNED:在机械测试中,这三种合金的扭转值相似。在XRD中,Ti-Nb的结构变化较小。在循环疲劳试验中,发现Ti-Nb相对于Ni-Ti和Ti-Mo具有显著更强的抗性。
    UNASSIGNED:根据我们的体外研究,由于Ti-Nb具有令人印象深刻的性能,因此建议将其用作制造旋转文件的可能合金。
    UNASSIGNED: The objective of this study was to compare the mechanical and structural properties of the nickel-titanium (Ni-Ti) alloy already used in endodontics with titanium-molybdenum (Ti-Mo) and titanium-niobium (Ti-Nb) alloys to determine if these can be suggested in the manufacture of endodontic files.
    UNASSIGNED: Orthodontic wires made of the different alloys were used. The previously mentioned alloys were characterized by energy-dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD) and torsion tests. Cyclic fatigue tests were performed on a simulated canal with a curvature of 86° to 375 rpm. The fractured surfaces of the wires were observed by means of scanning electron microscopy (SEM). A Kruskal-Wallis test and U Mann Whitney test were used to determine significant differences in cyclic fatigue between groups.
    UNASSIGNED: In the mechanical tests, similar values of torsion were found for the three alloys. In XRD, the Ti-Nb showed less structural changes. In the cyclic fatigue test, Ti-Nb was found to be significantly more resistant with respect to Ni-Ti and Ti-Mo.
    UNASSIGNED: Based on our in vitro study, Ti-Nb is suggested as a possible alloy for the manufacture of rotary files due to its impressive properties.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

公众号