背景:逆转录病毒被描述为慢性神经病变的危险因素。然而,它们是否可以作为肌萎缩侧索硬化症的触发因素,目前还不清楚。多年来,这种关联的一些案例已经被描述为异质披露。
方法:本研究旨在报告一例HIV和ALS样神经病变,并简要讨论临床方面的特点,如病理生理学和治疗方案。患者接受了与血液检查相关的神经系统检查,肌电图,脑脊液分析,和成像研究。
结论:在有关该主题的主要数据库中进行了非系统评价。该病例表现出混合的上下运动神经元体征,并根据目前的标准被认为是ALS的可能病例。
结论:经过短暂的随访和病毒载量清理,实现了神经稳定。
Retroviruses are described as a risk factor for chronic neuropathy. However, it is still unknown if they can work as amyotrophic lateral sclerosis triggers. Over the years, some cases of this association have been described with heterogenous disclosures.
This study aimed to report a case of HIV and ALS-like neuropathy and briefly discuss peculiarities of clinical aspects, such as physiopathology and treatment options. The patient underwent neurological examination associated with blood tests, electromyography, analysis of cerebrospinal fluid, and imaging studies.
A non-systematic review was performed in major databases regarding the topic. The case presented mixed upper and lower motor neuron signs and was framed as a probable case of ALS following the present criteria.
After a short follow-up and viral load cleansing, neurological stabilization was achieved.