背景:游泳性肺水肿(SIPE)是海军特种作战(NSW)学员中常见的呼吸系统疾病。目前尚不清楚诊断为SIPE的受训者的积极呼吸面板(RP)发现的发生率。
目的:新南威尔士州SIPE患者鼻咽标本中呼吸道病原体的发生率与对照组是否存在显着差异?
方法:对新南威尔士州Sea的临床信息进行回顾性分析,空气,以及在12个月内诊断为SIPE的Land(SEAL)团队候选人。表现出SIPE常见体征和症状的候选人接受了鼻咽拭子和RP常见呼吸道病原体测试。SIPE诊断得到了两视胸部X线摄影的支持。对没有SIPE的第一阶段学员的选定对照组进行了RP测试。
结果:1,048名海豹突击队队员中有45名被诊断为SIPE(4.3%)。五人患有肺炎。45个中的36个在RP上显示至少一种微生物的阳性结果(80%)。在研究小组中,人类鼻病毒/肠道病毒(RV/EV)是最常见的生物体(37.8%),其次是冠状病毒OC43(17.8%),和副流感病毒3型(17.8%)。对照组的68名候选人中有16名表现出阳性RP(24%)。SIPE和RP结果阳性的患者报告呼吸困难(94%),粉红泡沫痰(44%),和咯血(22%)比RP结果阳性的对照参与者更频繁。在研究组和对照组中报告呼吸道感染症状的人显示出更高的RP阳性发生率(P=0.046)。
结论:我们观察到80%诊断为SIPE的受训者在护理点RP上显示出阳性结果。此阳性率显着高于对照组的RP测试结果。这些发现表明,新南威尔士州候选人中呼吸道病原体的定植与SIPE的发展之间存在关联。
Swimming-induced pulmonary edema (SIPE) is a respiratory condition frequently seen among Naval Special Warfare (NSW) trainees. The incidence of positive respiratory panel (RP) findings in trainees with a diagnosis of SIPE currently is unknown.
Does a significant difference exist in the incidence of respiratory pathogens in nasopharyngeal samples of NSW candidates with SIPE and a control group?
Retrospective analysis of clinical information from NSW Sea, Air, and Land (SEAL) team candidates with a diagnosis of SIPE over a 12-month period. Candidates who demonstrated the common signs and symptoms of SIPE underwent a nasopharyngeal swab and RP test for common respiratory pathogens. SIPE diagnoses were supported by two-view chest radiography. RP tests were obtained for a selected control group of first-phase trainees without SIPE.
Forty-five of 1,048 SEAL team candidates received a diagnosis of SIPE (4.3%). Five had superimposed pneumonia. Thirty-six of 45 showed positive results for at least one microorganism on the RP (80%). In the study group, human rhinovirus/enterovirus (RV/EV) was the most frequently detected organism (37.8%), followed by coronavirus OC43 (17.8%), and parainfluenza virus type 3 (17.8%). Sixteen of 68 candidates from the control group showed positive RP (24%) findings. Patients with SIPE and positive RP results reported dyspnea (94%), pink frothy sputum (44%), and hemoptysis (36%) more frequently than the control participants with positive RP results. Those who reported respiratory infection symptoms in both the study and control groups showed higher incidences of positive RP results (P = .046).
We observed that 80% of trainees with a diagnosis of SIPE showed positive results on a point-of-care RP. This positivity rate was significantly higher than that of RP test results from the control cohort. These findings suggest an association between colonization with a respiratory pathogen and the development of SIPE in NSW candidates.