怀孕期间由尿路感染(UTI)引起的肺损伤很少见。在患有UTI的妊娠患者中及时检测肺部并发症对于防止母亲和胎儿的不良结局至关重要。这些并发症可能包括呼吸问题,肺水肿,以及先前存在的疾病的恶化,比如哮喘。我们旨在检测妊娠中UTI术后肺损伤的报告病例。
■我们通过详细的搜索策略,回顾性审查了截至2023年9月PubMed数据库中关于妊娠UTI后肺损伤的报道病例和文章。对选定的15篇文章的标题和摘要进行了评估,最终,根据我们的纳入和排除标准选择了7篇文章。
■大约1-2%的女性可能因持续性尿路感染而发展为急性肾盂肾炎,在某些情况下,这与肺水肿的风险增加有关。尿路感染会影响肺部健康。尿毒症,UTI的结果,会导致呼吸驱动的改变,力学,肌肉功能,和气体交换。此外,尿路感染引起的炎症激活嗜中性粒细胞并促进其募集到肺部,损害肺功能和损害周围组织。
■尽管对该主题的系统研究有限,尿路感染和肺损伤之间可能有联系。然而,目前尚不清楚妊娠是否会加剧这种关联.为了孕产妇健康,儿童健康,以及整个公共卫生,提高医生和妇科医生的认识很重要,以及不同的专业,如急诊和重症监护病房,关于妊娠UTI后肺损伤的更多信息;重要的是要注意UTI可能不会直接导致肺部并发症,但是与怀孕相关的生理变化会增加这种风险,所以更多的关心,观察,早期发现,和治疗对于治疗这些并发症和在患有UTI的孕妇中获得最佳结果至关重要。这方面需要更多的研究,由于妊娠UTI后肺损伤存在的潜在机制尚不清楚。
UNASSIGNED: Pulmonary injuries resulting from urinary tract infections (UTIs) during pregnancy are rare. Prompt detection of pulmonary complications in pregnant patients with UTIs is crucial to prevent adverse outcomes in both the mother and the fetus. These complications may include respiratory issues, pulmonary edema, and exacerbation of preexisting conditions, such as asthma. We aimed to detect reported cases of pulmonary injury after UTIs among pregnancies.
UNASSIGNED: We retrospectively reviewed the reported cases and articles in the PubMed database up to September 2023 on pulmonary injury after UTIs among pregnancies through a detailed search strategy. The titles and abstracts of the selected 15 articles were assessed, and ultimately, 7 articles were chosen based on adherence to our inclusion and exclusion criteria.
UNASSIGNED: Approximately 1-2% of women may develop acute pyelonephritis due to persistent UTIs, which has been associated with an increased risk of pulmonary edema in certain cases. UTIs can affect pulmonary health. Uremia, a consequence of UTIs, can lead to alterations in the respiratory drive, mechanics, muscle function, and gas exchange. Furthermore, urinary infection-induced inflammation activates neutrophils and promotes their recruitment to the lungs, compromising lung function and damaging the surrounding tissue.
UNASSIGNED: Although systematic research on this topic is limited, there may be a link between UTIs and pulmonary damage. However, it remains unclear whether pregnancy exacerbates this association. For maternal health, child health, and the whole public health, it is important to raise awareness of physicians and gynecologists, as well as the different specialties like emergency and intensive care units, with more information about pulmonary injury after UTI in pregnancy; it is important to note that UTIs may not directly cause pulmonary complications, but physiological changes associated with pregnancy can increase this risk, so more care, observation, early detection, and treatment are critical for treating these complications and achieving best outcome in pregnant women with UTIs. More research is needed in this area, as the mechanism underlying the existence of pulmonary damage post-UTI in pregnancy is unclear.