research misconduct

研究不端行为
  • 文章类型: Journal Article
    目的:作者是否知道他们在医学辅助生殖(MAR)领域的手稿中引用了撤回的论文?
    方法:进行了一项基于在线调查的横断面研究,以从引用撤回文章的相应作者那里获得有关引用模式的信息。从PubMed和RetractionWatch收集了MAR字段中缩回的文章的数据集。检索了引用每篇撤回文章的已发表文章的完整列表。该调查通过电子邮件分发给在研究中引用了撤回论文的通讯作者。
    结果:调查显示作者明显缺乏意识,78.7%的人不知道他们引用了撤回的文章。这种缺乏意识的原因是研究数据库和期刊内的通知机制不足,以及对以前存储的手稿副本的依赖。一个值得注意的发现是,参考检查通常由单个作者执行,在同行评审过程中没有提出撤回问题的实例。只有一小部分(17.8%)的受访者表示在期刊网站和科学数据库上都验证了撤回通知。
    结论:更正包含随后撤回的参考文献的出版物对于系统评价具有重要意义,荟萃分析和指南。引用撤回的文章使错误的科学数据永存,但是评估引文的准确性需要相当大的努力。正确通知撤回状态和交叉检查引文可以帮助防止错误。
    OBJECTIVE: Are authors aware when they have cited a retracted paper in their manuscripts in the medically assisted reproduction (MAR) field?
    METHODS: A cross-sectional study based on an online survey was conducted to acquire information on the citation pattern from corresponding authors who had cited a retracted article. A dataset of retracted articles in the MAR field was collected from PubMed and Retraction Watch. A complete list of published articles that cited each retracted article was retrieved. The survey was distributed via e-mail to corresponding authors who had cited a retracted paper in their study.
    RESULTS: The survey revealed a significant lack of awareness among authors, with 78.7% unaware that they had cited retracted articles. This lack of awareness was attributed to insufficient notification mechanisms within research databases and journals, alongside a reliance on previously stored copies of manuscripts. A notable finding was that reference checks were typically performed by a single author, with no instances of retraction concerns raised during the peer-review process. Only a small fraction (17.8%) of respondents reported verifying retraction notices on both journal websites and scientific databases.
    CONCLUSIONS: Correcting publications that contain references which are subsequently retracted is significant for systematic reviews, meta-analyses and guidelines. Citations of retracted articles perpetuate erroneous scientific data, but assessing the accuracy of citations requires considerable effort. Proper notification of retraction status and cross-checking of citations can help to prevent errors.
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  • 文章类型: Journal Article
    PubPeer的创始人将其网站设想为“期刊俱乐部”的在线形式,以促进出版后的同行评审。最近,PubPeer的评论导致了大量的研究不当行为程序-当当前的联邦研究不当行为法规在二十年前制定时,这种发展是无法预料的。然而,数字,频率,以及识别数据完整性问题的PubPeer评论的速度,以及将所有此类评论视为潜在研究不当行为指控的机构和政府做法,使机构不堪重负,并威胁要将注意力和资源从其他研究诚信计划中转移出去。最近,备受瞩目的研究不端行为案例突显了公众对研究诚信的兴趣,并不可避免地使用PubPeer等平台来挑战研究成果。本文探讨了PubPeer的起源及其在基于在线的科学出版物搜寻潜在问题的现代时代中的核心作用,并概述了机构在解决PubPeer上发现的问题时必须管理的挑战。总之,我们讨论了联邦法规规定的对调查过程的一些潜在增强,如果实施,允许机构更有效地管理其中一些挑战。
    The founders of PubPeer envisioned their website as an online form of a \"journal club\" that would facilitate post-publication peer review. Recently, PubPeer comments have led to a significant number of research misconduct proceedings - a development that could not have been anticipated when the current federal research misconduct regulations were developed two decades ago. Yet the number, frequency, and velocity of PubPeer comments identifying data integrity concerns, and institutional and government practices that treat all such comments as potential research misconduct allegations, have overwhelmed institutions and threaten to divert attention and resources away from other research integrity initiatives. Recent, high profile research misconduct cases accentuate the increasing public interest in research integrity and make it inevitable that the use of platforms such as PubPeer to challenge research findings will intensify. This article examines the origins of PubPeer and its central role in the modern era of online-based scouring of scientific publications for potential problems and outlines the challenges that institutions must manage in addressing issues identified on PubPeer. In conclusion, we discuss some potential enhancements to the investigatory process specified under federal regulations that could, if implemented, allow institutions to manage some of these challenges more efficiently.
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  • 文章类型: Journal Article
    先前的研究发现,性别和学术职位等因素不会影响机构采取的行政行为的严重程度。然而,这项研究提供了部分不一致的证据.它侧重于中国大陆医院的研究不端事件,并使用大型横截面数据集(N=815)探讨与惩罚相关的因素。回归分析显示,作者顺序与惩罚强度之间存在显着相关性(p<0.05)。在特定条件下,职称(高级)与处罚强度显著相关(p=0.001),以及职称和研究不当行为类型之间的相互作用。对简单效应的进一步分析表明,在伪造和伪造的情况下,以及多种研究不当行为的组合,具有高级职称的研究人员受到的惩罚比具有初级职称的研究人员轻得多,中间,和副高级职称(p<0.05)。这项研究揭示了中国内地医院可能采用的潜在问责模式(集体问责和分级惩罚),以及在确保公平方面面临的挑战,强调独立调查机构对研究不端行为事件的重要性,并倡导将公平作为治理研究不端行为的优先事项。
    Previous studies have found that factors such as gender and academic positions do not influence the severity of administrative actions taken by institutions. However, this study provides partly inconsistent evidence. It focuses on incidents of research misconduct in hospitals across Mainland China and explores factors related to punishment using a large cross-sectional dataset (N = 815). Regression analysis revealed a significant correlation between authorship order and the punishment intensity (p < 0.05). Under specific conditions, there was a significant correlation between the professional title (senior) and punishment intensity (p = 0.001), and an interaction between professional title and types of research misbehavior. Further analysis of simple effects showed that, in cases of fabrication and falsification, and combinations of multiple research misbehavior, researchers with senior titles received significantly lighter punishments compared to those with junior, intermediate, and associate senior titles (p < 0.05). The study unveils the potential accountability patterns (collective accountability and tiered punishment) that may be adopted by hospitals in Mainland China, as well as the challenges faced in ensuring fairness, emphasizing the importance of independent investigative bodies for incidents of research misconduct, and advocating for fairness as a priority in governance of research misconduct.
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  • 文章类型: Journal Article
    在学术研究中,研究员欺诈通常很容易和诱人,几乎没有被发现的风险。广泛的欺诈案件继续发生。未被发现的欺诈数量是未知的,可能是巨大的。解决研究人员欺诈的三种策略是(a)在提出欺诈指控后进行回顾性调查,(b)在欺诈发生时提供确凿证据的操作,和(c)防止欺诈发生的数据管理做法。解决研究人员欺诈的机构和监管努力几乎完全集中在追溯策略上。由于事后科学证据的局限性,回顾性方法存在争议,在某些情况下,很难确定谁实际犯下了欺诈行为,法律证据标准的应用远低于科学中通常的证据标准,以及调查欺诈的科学家缺乏法律专业知识。回顾性策略可能是可靠有效的,主要是在广泛的情况下,粗心的欺诈。Sting操作可以克服这些限制和争议,但在许多情况下是不可行的。在政府机构监管的临床试验中,有效防止研究人员欺诈和无意错误的数据管理实践已经确立,但在大多数学术研究中似乎在很大程度上是未知或未实现的。既定的数据管理实践包括:存档原始数据的安全副本,审计跟踪,限制对数据和数据收集过程的访问,软件验证,质量控制检查,盲法,数据处理和分析程序的预注册,和直接解决欺诈问题的研究审计。当前有关学术研究中数据管理的讨论集中在共享数据上,而很少注意防止有意和无意错误的实践。可以建立诸如错误控制的数据管理之类的名称或徽章,以表明采用有效解决有意和无意错误的数据管理实践进行的研究。
    Researcher fraud is often easy and enticing in academic research, with little risk of detection. Cases of extensive fraud continue to occur. The amount of fraud that goes undetected is unknown and may be substantial. Three strategies for addressing researcher fraud are (a) retrospective investigations after allegations of fraud have been made, (b) sting operations that provide conclusive evidence of fraud as it occurs, and (c) data management practices that prevent the occurrence of fraud. Institutional and regulatory efforts to address researcher fraud have focused almost exclusively on the retrospective strategy. The retrospective approach is subject to controversy due to the limitations of post-hoc evidence in science, the difficulty in establishing who actually committed the fraud in some cases, the application of a legal standard of evidence that is much lower than the usual standards of evidence in science, and the lack of legal expertise by scientists investigating fraud. The retrospective strategy may be reliably effective primarily in cases of extensive, careless fraud. Sting operations can overcome these limitations and controversies, but are not feasible in many situations. Data management practices that are effective at preventing researcher fraud and unintentional errors are well-established in clinical trials regulated by government agencies, but appear to be largely unknown or unimplemented in most academic research. Established data management practices include: archiving secure copies of the raw data, audit trails, restricted access to the data and data collection processes, software validation, quality control checks, blinding, preregistration of data processing and analysis programs, and research audits that directly address fraud. Current discussions about data management in academic research focus on sharing data with little attention to practices that prevent intentional and unintentional errors. A designation or badge such as error-controlled data management could be established to indicate research that was conducted with data management practices that effectively address intentional and unintentional errors.
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  • 文章类型: Journal Article
    研究不端,广义上定义为制造行为,伪造和/或抄袭,违反科学的价值体系,大量浪费公共资源,在更极端的情况下危及研究参与者或整个社会的成员。确定研究不当行为的罪责需要确定被告或犯罪者的意图。然而,“意图”是一种心态,它的感知是主观的,与行为本身可用的客观证据相比,不容易确定的明确证据。这里,我们探索研究不端行为中的“意图”概念,它是如何用犯罪学/法律术语来构建的,从心理学的角度叙述。基于这些,我们提出了一个质疑和调查的框架,根据立法条款的定义,并由心理学的模型和工具提供信息,可能有助于为有罪意图建立大量证据。这样一个框架可能有助于研究不当行为裁决和实施制裁。
    Research misconduct, broadly defined as acts of fabrication, falsification and/or plagiarism, violate the value system of science, cost significant wastage of public resources, and in more extreme cases endanger research participants or members of the society at large. Determination of culpability in research misconduct requires establishment of intent on the part of the respondent or perpetrator. However, \"intent\" is a state of mind, and its perception is subjective, unequivocal evidence for which would not be as readily established compared to the objective evidence available for the acts themselves. Here, we explore the concept of \"intent\" in research misconduct, how it is framed in criminological/legal terms, and narrated from a psychological perspective. Based on these, we propose a framework whereby lines of questioning and investigation, as defined by legislative terms and informed by the models and tools of psychology, could help in establishing a preponderance of evidence for culpable intent. Such a framework could be useful in research misconduct adjudications and in delivering sanctions.
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  • 文章类型: Journal Article
    目的:撤回旨在作为一种机制,在必要时由于欺诈性而纠正已发布的知识体系,致命缺陷或道德上不可接受的出版物。然而,这种机制的成功要求被撤回的出版物被一致地识别为这样,撤回通知包含足够的信息来理解什么被撤回以及为什么被撤回。我们的研究调查了如何清楚地和一致地将公共卫生中的出版物提交给研究人员。
    方法:这是一项横断面研究,使用441个撤回的公共卫生领域的研究出版物。从11个资源中检索了这些出版物的记录,而撤回通知是从出版商网站和全文聚合器检索的。使用出版伦理委员会(COPE)和国家医学图书馆(NLM)的标准对出版物的撤回状态进行了评估。使用COPE和RetractionWatch的标准评估了相关撤回通知的完整性。
    结果:检索了2841条撤回出版物的记录,其中不到一半的人表示该条款已被撤回。只有不到5%的出版物被认为是通过所有可用资源收回的。在单一资源中,是否以及如何识别撤回的出版物各不相同。收回通知经常不完整,没有符合所有标准的通知。
    结论:观察到的不一致和不完整的通知对科学出版的完整性构成威胁,并强调需要更好地与现有的最佳做法保持一致,以确保更有效和透明地传播撤回信息。
    OBJECTIVE: Retraction is intended to be a mechanism to correct the published body of knowledge when necessary due to fraudulent, fatally flawed, or ethically unacceptable publications. However, the success of this mechanism requires that retracted publications be consistently identified as such and that retraction notices contain sufficient information to understand what is being retracted and why. Our study investigated how clearly and consistently retracted publications in public health are being presented to researchers.
    METHODS: This is a cross-sectional study, using 441 retracted research publications in the field of public health. Records were retrieved for each of these publications from 11 resources, while retraction notices were retrieved from publisher websites and full-text aggregators. The identification of the retracted status of the publication was assessed using criteria from the Committee on Publication Ethics and the National Library of Medicine. The completeness of the associated retraction notices was assessed using criteria from Committee on Publication Ethics and Retraction Watch.
    RESULTS: Two thousand eight hundred forty-one records for retracted publications were retrieved, of which less than half indicated that the article had been retracted. Less than 5% of publications were identified as retracted through all resources through which they were available. Within single resources, if and how retracted publications were identified varied. Retraction notices were frequently incomplete, with no notices meeting all the criteria.
    CONCLUSIONS: The observed inconsistencies and incomplete notices pose a threat to the integrity of scientific publishing and highlight the need to better align with existing best practices to ensure more effective and transparent dissemination of information on retractions.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    科学研究需要客观性,公正和严格。然而,学术文献中充斥着缺乏可重复性或有效性的初步和探索性发现。一些具有高影响力的低质量论文已成为公众关注的焦点。研究人员的集体努力遵循这些错误的线索,沿着盲巷和僵局走下去,是浪费时间和资源,这对早期职业研究人员尤其有害。此外,非专业公众也可能受到与调查结果相关的社会经济影响的影响。有争议的是,科学研究的性质是这样的,即其前沿是通过发表的主张的循环来移动和塑造的,这反过来又引起了其他人的验证。使用最近的室温超导材料研究的例子,相反,我认为发表缺乏可重复性或有效性的明显重要或壮观的主张在认识论和社会上是不负责任的。如果作者拒绝分享研究材料和原始数据以供他人验证,情况更是如此。这种行为不会推进,反而会破坏科学,并应受到研究界内部关于材料和数据共享的协商一致管理规则的禁止,适当制裁的不当行为。
    Scientific research requires objectivity, impartiality and stringency. However, scholarly literature is littered with preliminary and explorative findings that lack reproducibility or validity. Some low-quality papers with perceived high impact have become publicly notable. The collective effort of fellow researchers who follow these false leads down blind alleys and impasses is a waste of time and resources, and this is particularly damaging for early career researchers. Furthermore, the lay public might also be affected by socioeconomic repercussions associated with the findings. It is arguable that the nature of scientific research is such that its frontiers are moved and shaped by cycles of published claims inducing in turn rounds of validation by others. Using recent example cases of room-temperature superconducting materials research, I argue instead that publication of perceptibly important or spectacular claims that lack reproducibility or validity is epistemically and socially irresponsible. This is even more so if authors refuse to share research materials and raw data for verification by others. Such acts do not advance, but would instead corrupt science, and should be prohibited by consensual governing rules on material and data sharing within the research community, with malpractices appropriately sanctioned.
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  • 文章类型: Journal Article
    背景:随着众多科学产出的出现,研究不端行为日益受到重视。本研究旨在调查知识,中国西南地区医学居民对研究不端行为的态度和实践。
    方法:从2022年11月至2023年3月在中国西南地区进行了横断面研究。将问卷的链接发送给17家三级医院的教学管理科主任。收集并分析了答案。采用Logistic回归分析探讨居民科研不端行为的相关因素。
    结果:6200名居民被纳入研究,88.5%的参与者参加了研究诚信课程,但53.7%的参与者承认有至少一种形式的研究不端行为.有研究生或以上学历,以第一作者或通讯作者的身份发表论文,参加研究诚信课程,对研究完整性的自我报告知识较低,对研究不当行为的感知后果较低,与研究不当行为呈正相关。担任研究项目的主要研究员与研究不当行为呈负相关。大多数居民(66.3%)认为研究不端行为的原因是研究人员缺乏研究能力。
    结论:中国西南地区居民自我报告的研究不端行为率很高,这凸显了在住院医师项目中加强研究诚信课程的普遍必要性。中国当前培训的无效性表明,全球可能需要重新评估和改进教育方法以促进研究诚信。应对这些挑战不仅对于中国医学研究和患者护理的信誉至关重要,而且对于保持全球医学教育的最高道德标准也至关重要。政策制定者,教育工作者,和全球范围内的医疗保健领导者应合作建立全面的战略,以确保负责任的研究进行,最终维护医学进步的完整性,并促进对跨境科学努力的信任。
    BACKGROUND: With the emergence of numerous scientific outputs, growing attention is paid to research misconduct. This study aimed to investigate knowledge, attitudes and practices about research misconduct among medical residents in southwest China.
    METHODS: A cross-sectional study was conducted in southwest China from November 2022 through March 2023. The links to the questionnaire were sent to the directors of the teaching management department in 17 tertiary hospitals. Answers were collected and analyzed. Logistic regression analysis was performed to explore the factors associated with research misconduct among residents.
    RESULTS: 6200 residents were enrolled in the study, and 88.5% of participants attended a course on research integrity, but 53.7% of participants admitted to having committed at least one form of research misconduct. Having a postgraduate or above, publishing papers as the first author or corresponding author, attending a course on research integrity, lower self-reported knowledge on research integrity and lower perceived consequences for research misconduct were positively correlated to research misconduct. Serving as a primary investigator for a research project was negatively associated with research misconduct. Most residents (66.3%) agreed that the reason for research misconduct is that researchers lack research ability.
    CONCLUSIONS: The high self-reported rate of research misconduct among residents in southwest China underscores a universal necessity for enhancing research integrity courses in residency programs. The ineffectiveness of current training in China suggests a possible global need for reevaluating and improving educational approaches to foster research integrity. Addressing these challenges is imperative not only for the credibility of medical research and patient care in China but also for maintaining the highest ethical standards in medical education worldwide. Policymakers, educators, and healthcare leaders on a global scale should collaborate to establish comprehensive strategies that ensure the responsible conduct of research, ultimately safeguarding the integrity of medical advancements and promoting trust in scientific endeavors across borders.
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  • 文章类型: Journal Article
    调查针对高级官员的研究不当行为指控可能会给大学造成重大的利益冲突(COI),这可能需要改变现有的监督框架。解决其中一些挑战的一种方法是制定政策和程序,专门针对涉及大学高级官员的不当行为指控进行调查。现在也可以采取步骤,而不管是否创建了这样的主体。联邦和大学研究不当行为法规和政策可能需要修订,以便为机构提供更清晰的指导,说明如何处理针对高级官员的不当行为指控。对他们来说,机构可以从主动创建和透明地披露自己的程序中受益,以独立调查针对高级官员的研究不当行为指控。
    Investigating research misconduct allegations against top officials can create significant conflicts of interest (COIs) for universities that may require changes to existing oversight frameworks. One way of addressing some of these challenges is to develop policies and procedures that specifically address investigation of allegations of misconduct involving top university officials. Steps can also be taken now regardless of whether such a body is created. Federal and university research misconduct regulations and policies may need to be revised to provide institutions with clearer guidance on how to deal with misconduct allegations against top officials. For their part, institutions may benefit from proactively creating and transparently disclosing their own processes for independent investigation of research misconduct allegations against senior officials.
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