■尽管推出了几种防龋产品,龋齿仍然是一个全球性问题。近年来,通过采用再矿化概念对无空洞性龋齿病变进行非侵入性治疗的兴趣日益增加.每种再矿化剂都有其自身的缺点。因此,需要寻求新的试剂,其提供具有较低有害反应的较早对应物的优点。
■这项研究的目的是评估基于纳米颗粒的材料对儿童白斑病变(WSL)的再矿化功效。
■选择45名年龄在4至8岁之间的WSL儿童,并随机分为三组。在基线,使用国际龋齿检测和评估系统II(ICDASII)标准对具有WSL的牙齿进行确认和识别,并使用照相方法测量病变的尺寸。然后,他们被随机分为三组,每组15个样本,第一组纳米氟化银(NSF),II组纳米羟基磷灰石(nano-HAP)血清,和III组MI清漆。在此之后,涂了清漆,随访是在2号完成的,第四,12th,第24周。
■到第4周,三组差异均有统计学意义(p<0.05)。第一组的基线测量,II,和III显示它们各自的平均WSL尺寸为4.9±0.66、4.27±0.69和5.44±2.95。到第24周,各组的尺寸分别降低到1.22±0.46、0.93±0.41和2.19±1.40。总的来说,II组(纳米HAP血清)在第24周结束时显示出病变尺寸的统计学显着降低,其次是第一组和第三组。
■牙釉质的再矿化是由所有三种试剂诱导的。纳米HAP血清比MI清漆和NSF更成功。
■AnnaduraiT,VundelaRR,ChowdharyN,etal.基于纳米颗粒的材料对儿童白斑病变的再矿化功效评估:一项比较临床研究。IntJClinPediatrDent2024;17(4):425-432。
UNASSIGNED: Despite the introduction of several anticaries products, dental caries continues to be a global problem. In recent years, there has been a rise in interest in noninvasive treatment for noncavitated caries lesions by employing
remineralization concepts. Each remineralizing agent has its own drawbacks. Therefore, it is desirable to seek new agents that offer the advantages of earlier counterparts with lower detrimental reactions.
UNASSIGNED: The purpose of this research is to evaluate the
remineralization efficacy of nanoparticle-based materials on white spot lesion (WSL) in children.
UNASSIGNED: A total of 45 children between the age-group of 4 and 8 years with WSLs were selected and randomly divided into three groups. At baseline, the teeth with WSLs were confirmed and identified using International Caries Detection and Assessment System II (ICDAS II) criteria, and the dimensions of the lesions were measured using photographic methods. Then, they were randomly placed into three groups of 15 samples each-group I nanosilver fluoride (NSF), group II nanohydroxyapatite (nano-HAP) serum, and group III MI varnish. Following that, the varnish was applied, and follow-up was done in the 2nd, 4th, 12th, and 24th week.
UNASSIGNED: By the 4th week, all three groups had a statistically significant difference (p < 0.05). Baseline measurements for groups I, II, and III showed that their respective mean WSL dimensions were 4.9 ± 0.66, 4.27 ± 0.69, and 5.44 ± 2.95. The dimensions of each group were reduced by the 24th week to 1.22 ± 0.46, 0.93 ± 0.41, and 2.19 ± 1.40, respectively. Overall, group II (nano-HAP serum) showed a statistically significant decrease in the dimension of the lesion at the end of the 24th week, followed by groups I and III.
UNASSIGNED: The
remineralization of enamel was induced by all three agents. Nano-HAP serum is more successful than MI Varnish and NSF.
UNASSIGNED: Annadurai T, Vundela RR, Chowdhary N, et al. Evaluation of
Remineralization Efficacy of Nanoparticle-based Materials on White Spot Lesions in Children: A Comparative Clinical Study. Int J Clin Pediatr Dent 2024;17(4):425-432.