■评估基质内透镜植入治疗远视的有效性和安全性。
■对PubMed的系统搜索,WebofScience,Embase,科克伦图书馆,中国全民知识互联网,和万方数据库确定了直到2023年1月的小切口基质内透镜植入术矫正远视的研究。乔安娜·布里格斯研究所(JBI)的关键评估工具被用来评估回顾性研究的质量,使用非随机研究方法学指数(MINORS)评估前瞻性研究的质量。这项研究包括术后视觉结果,角膜形态学,和生物力学结果。
■共鉴定出456篇文章,其中10人纳入荟萃分析.包括10项单臂研究,涉及190只眼。一项荟萃分析表明,角膜基质内透镜植入治疗可显着改善远视。未矫正远距视力(UDVA)较术前值显著提高(p=0.027),矫正视力与术前相比无差异(p=0.27),87%的眼睛在CDVA的Snellen系中没有一个或多个系的损失(p<0.00001)。球面等效屈光度(SE)与术前检查有显著性差异(p<0.00001),52%的眼睛有±0.5屈光度(D)术后SE(p<0.00001),74%的眼术后SE为±1.0D(p<0.00001)。与术前相比,中央角膜厚度(CCT)增加了72.68μm(p<0.00001),角膜曲率增加4.18D(p<0.00001)。Q值下降0.82(p<0.00001),高阶像差(HOA)降低0.66(p<0.00001)。
■小切口基质内透镜植入可能是矫正远视的有效解决方案。视力改善效果显著,但需要进一步探索角膜生物力学的变化和长期安全性。系统审查注册:https://www。crd.约克。AC.英国/PROSPERO/,标识符:CRD42023432343。
UNASSIGNED: To assess the efficacy and safety of intrastromal lenticule implantation for the treatment of hyperopia.
UNASSIGNED: A systematic search of PubMed, Web of Science, Embase, Cochrane Library, China National Knowledge Internet, and Wan Fang Database identified studies on small-incision intrastromal lenticule implantation for hyperopia correction until January 2023. The Joanna Briggs Institute (JBI) critical appraisal tool was used to assess the quality of the retrospective research, and the Methodological Index for Non-randomized Studies (MINORS) was used to assess the quality of the prospective research. This study included postoperative visual outcomes, corneal morphology, and biomechanical outcomes.
UNASSIGNED: A total of 456 articles were identified, of which 10 were included in the meta-analysis. Ten single-arm studies involving 190 eyes were included. A meta-analysis demonstrated that corneal intrastromal lenticule implantation treatment significantly improved hyperopia. Uncorrected distance visual acuity (UDVA) significantly improved compared to the preoperative value (p = 0.027), corrected distance visual acuity showed no difference compared to the preoperative value (p = 0.27), and 87% eyes have no loss of one or more lines in the Snellen lines of CDVA (p < 0.00001). There was a significant difference between the spherical equivalent
refractive (SE) and preoperative examination (p < 0.00001), 52% of eyes had ±0.5 diopters (D) postoperative SE (p < 0.00001), and 74% eyes had ±1.0 D postoperative SE (p < 0.00001). The central corneal thickness (CCT) increased by 72.68 μm compared to that preoperatively (p < 0.00001), and corneal curvature increased by 4.18D (p < 0.00001). The Q-value decreased by 0.82 (p < 0.00001), and higher-order aberration (HOA) decreased by 0.66 (p < 0.00001).
UNASSIGNED: Small-incision intrastromal lenticule implantation may be an effective solution for correcting hyperopia. The effect of improved vision is significant, but further exploration is needed for changes in corneal biomechanics and long-term safety.Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42023432343.