皮肤平滑肌瘤是良性和罕见的平滑肌肿瘤。生殖器平滑肌瘤包括位于乳头的平滑肌瘤,阴囊,乳晕或外阴。乳头平滑肌瘤是最不常见的生殖器平滑肌瘤,常见于中年妇女。这里,我们介绍了一例40岁的女性,抱怨右乳头生长六个月。在当地考试中,这是一个1cm×1cm生长在乳头的侧面。最后,完成了完全切除的治疗计划.严重的,这是一个界限清楚的皮肤覆盖的软组织钻头,皮瓣尺寸为0.6cmx0.6cm,软组织尺寸为0.6cmx0.5cmx0.2cm。组织病理学检查显示,皮肤覆盖的真皮切片显示出界限分明的未包裹病变,显示梭形细胞的交叉束,没有发现异型或有丝分裂。微观上,生长有无瘤切除边缘.用S100,平滑肌肌动蛋白(SMA)和caldesmon进行免疫组织化学确认。诊断为乳头平滑肌瘤,SMA阳性。乳头平滑肌瘤是一种罕见的,良性病变,需要在显微镜下正确诊断。活检和免疫组织化学是一项确证性研究,可以及时治疗患者。
Cutaneous leiomyomas are benign and rare smooth muscle tumors. Genital leiomyoma includes leiomyomas located in the nipple, scrotum, areola or vulva. Nipple leiomyomas are the least common genital leiomyomas and are commonly seen to occur in middle-aged women. Here, we present a case of a 40-year-old female complaining of a growth over the right nipple for six months. On local examination, it was a 1cm x 1cm growth on the lateral aspect of the nipple. Finally, a treatment plan of complete excision was done. Grossly, it was a well-circumscribed skin-covered soft tissue bit with a skin flap measuring 0.6cm x 0.6cm and soft tissue measuring 0.6cm x 0.5cm x 0.2cm. Histopathological examination revealed a skin-covered section with dermis showing a well-circumscribed unencapsulated lesion that showed intersecting fascicles of spindle cells with no atypia or mitoses noted. Microscopically, the growth had tumor-free resection margins. Immunohistochemical confirmation with S100, smooth muscle actin (SMA) and caldesmon was done. Diagnosis of nipple leiomyoma was given with strong SMA positivity. Nipple leiomyoma is a rare, benign lesion and needs to be correctly diagnosed microscopically. Biopsy and immunohistochemistry is a confirmatory investigation that can lead to timely management of the patient.