radiation dose

辐射剂量
  • 文章类型: Journal Article
    这项研究的重点是确定胸部X射线照相术中X射线室的散射辐射水平。对108例患者进行了检查。四台X光机(A,B,C,和D)在三个中心的研究过程中使用。在这项研究中考虑了三个位置;位置Q就在(Bucky立场)旁边,位置R,距离Bucky支架左侧150厘米,朝向门和位置T,从Bucky支架到射线技师的防护屏分别为200厘米。两台机器(A和B)来自中心1,一台机器来自中心2(C),一台机器来自中心3(D)。参与者的体重指数(BMI)范围为20至25kgm-2,平均值为23.97kgm-2。在任何暴露之前使用Radalert100m读取背景辐射水平,平均背景水平为0.298mR/h。从位置Q相对于四个机器A获得的散射辐射剂量的平均值,B,C,D,分别为0.109、0.201、0.204、0.200mR/h(9.166、16.903、17.156、16.819mSv/yr),其标准偏差分别为±0.052、±0.053、±0.064和±0.081。结果与以前的研究相当。该研究建议对员工进行教育和培训,以确定辐射水平,以增强工作安全。
    This research focused on the determination of scatter radiation levels in x-ray rooms during chest radiography. 108 patients were examined. Four x-ray machines (A, B, C, and D) were used during the research from three centers. Three positions were considered in this study; position Q just beside the (Bucky stand), position R, which is 150 cm from the left of the Bucky stand towards the door and position T, 200 cm from the Bucky stand to the radiographer\'s protective screen respectively. Two machines (A and B) from center 1 and one machine from center 2 (C) and one machine from center 3 (D). The body mass index (BMI) of the participants ranged from 20 to 25 kgm-2 with mean value of 23.97 kgm-2. The background radiation level was read using Radalert 100 m before any exposure, and the mean background level was 0.298 mR/h. The mean of the scatter radiation doses obtained from positions Q with respect to the four machines A, B, C, and D, were 0.109, 0.201, 0.204, 0.200 mR/h (9.166, 16.903, 17.156, 16.819 mSv/yr) and their standard deviations were ±0.052, ±0.053, ±0.064, and ±0.081 respectively. The results were comparable with previous studies. The study recommends staff education and training in determination of radiation levels for enhanced work safety.
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  • 文章类型: Journal Article
    天然放射性核素的活性浓度,氡活度浓度,已经研究了Atiwa西区金矿社区土壤中的质量和面积呼气率。通过伽马射线光谱法测定天然放射性核素,同时使用CR-39检测器测量氡浓度。平均活性浓度为26.9±1.7Bq/kg,57.5±3.6Bq/kg,Ra-226、Th-232、K-40和Rn-222分别为237.5±17.6Bq/kg和560.0±54Bq/m3。评估的质量呼气速率范围为2.8±0.3至6.5±0.7×10-5Bq/kg/h,而面积呼气速率为0.8±0.09至2.0±0.21×10-3Bq/m2/h。一些采矿和农业地区的呼气率高,表明这些地区使用土壤作为建筑材料可能对人口造成一定程度的辐射危害。评估的放射风险低于参考水平。在Ra-226和Rn-222活性浓度之间以及在所研究的土壤中观察到良好的线性相关性。皮尔逊相关系数,用聚类分析和主成分分析研究确定的研究参数之间的关系。
    The activity concentration of natural radionuclides, radon activity concentration, mass and area exhalation rates have been studied in soils from gold mining communities in Atiwa West district. The natural radionuclides were determined by gamma ray spectrometry method while radon concentrations were measured using CR-39 detectors. The mean activity concentrations were found to be 26.9 ± 1.7 Bq/kg, 57.5 ± 3.6 Bq/kg, 237.5 ± 17.6 Bq/kg and 560.0 ± 54 Bq/m3 for Ra-226, Th-232, K-40 and Rn-222 respectively. The evaluated mass exhalation rates ranged from 2.8 ± 0.3 to 6.5 ± 0.7 × 10-5 Bq/kg/h while the area exhalation rates were from 0.8 ± 0.09 to 2.0 ± 0.21 × 10-3 Bq/m2/h. Some mining and farming areas recorded high exhalation rates indicating that the use of soils as building materials from such areas could pose a level of radiation hazard to the population. The evaluated radiological risks were below reference levels. A good linear correlation was observed between Ra-226 and Rn-222 activity concentrations and in the investigated soils. The Pearson correlation coefficient, cluster analysis and principal component analysis were used to study the relationship between the determined parameters of the study.
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  • 文章类型: Journal Article
    在计算机断层扫描(CT)中,器官剂量调制(ODM)减少了来自前侧的辐射暴露,以减少位于前部的辐射敏感器官接收的辐射剂量。我们研究了ODM应用于扫描范围的一部分对人体CT辐射剂量的影响。在有或没有ODM的情况下,对拟人化全身体模的胸部和胸腹盆腔区域进行成像。ODM被应用于各个地区,并对管电流调制曲线进行了比较。此外,比较了800例患者的胸椎和胸腹腹肾盂CT中是否有ODM的剂量指数。ODM适用于男性患者的甲状腺,女性患者的甲状腺和乳腺。在胸部的幻影成像中,ODM在扫描范围以下的应用降低了管电流,乳房的数量进一步减少。在ODM低于扫描范围的情况下,在胸腹盆腔区域的体模成像中也观察到管电流降低。以及ODM对整个扫描范围的应用,甲状腺,乳房,甲状腺和乳腺进一步降低了ODM应用区域的管电流。在患者成像中,ODM的剂量指数明显低于无ODM,无论扫描范围或性别。胸腹腹骨盆CT的剂量长度乘积绝对减少较大(男性,43.2mGy·cm;雌性,比胸部CT(男性,30.8mGy·cm;雌性,男女均为37.6mGy·cm),表明未应用ODM的腹盆腔区域的剂量减少。总之,ODM在身体CT中的应用不仅减少了ODM被应用的区域中的辐射剂量,而且减少了该区域之外的辐射剂量。在辐射剂量管理中,应当考虑到,即使应用于有限区域的ODM也会影响剂量指数。 .
    In computed tomography (CT), organ dose modulation (ODM) reduces radiation exposure from the anterior side to reduce radiation dose received by the radiosensitive organs located anteriorly. We investigated the effects of ODM applied to a part of the scan range on radiation dose in body CT. The thorax and thoraco-abdominopelvic region of an anthropomorphic whole-body phantom were imaged with and without ODM. ODM was applied to various regions, and the tube current modulation curves were compared. Additionally, the dose indices were compared with and without ODM in thoracic and thoraco-abdominopelvic CTs in 800 patients. ODM was applied to the thyroid in male patients and to the thyroid and breast in female patients. In phantom imaging of the thorax, the application of ODM below the scan range decreased the tube current, and that to the breast showed a further decrease. Decreased tube current was also observed in phantom imaging of the thoraco-abdominopelvic regions with ODM below the scan range, and the application of ODM to the whole scan range, thyroid, breast, and both thyroid and breast further reduced the tube current in the region to which ODM was applied. In patient imaging, the dose indices were significantly lower with ODM than without ODM, regardless of the scan range or sex. The absolute reduction in dose-length product was larger for thoraco-abdominopelvic CT (male, 43.2 mGy∙cm; female, 59.7 mGy∙cm) than for thoracic CT (male, 30.8 mGy∙cm; female, 37.6 mGy∙cm) in both sexes, indicating dose reduction in the abdominopelvic region to which ODM was not applied. In conclusion, The application of ODM in body CT reduces radiation dose not only in the region to which ODM is applied but also outside the region. In radiation dose management, it should be considered that even ODM applied to a limited region affects the dose indices. .
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  • 文章类型: Journal Article
    为了验证在各种扫描设置下使用光子计数探测器(PCD)CT进行冠状动脉钙积分(CACS)的准确性,并探索考虑准确性和辐射剂量的优化扫描设置。CACS体模包含六个两种大小,三种密度的空心圆柱形羟基磷灰石钙化,对12名患者进行了CACS扫描。对于PCD-CT,两种扫描模式(顺序和闪光[高螺距螺旋模式])和五个管电压(90kV,120kV,140kV,Sn100kV,和Sn140kV)在不同的图像质量(IQ)水平下被设置为体模,患者在IQ19下以120kV闪烁模式扫描。在70keV下重建来自PCD-CT的所有采集。在能量积分检测器CT(EID-CT)上以120kV的顺序模式采集用作参考。Agatston,质量,并计算体积分数。来自PCD-CT的CACS与参考表现出极好的一致性(所有组内相关系数[ICC]>0.99)。从PCD-CT获得的Agatston评分与参考(5.4-11.5)之间的均方根误差(RMSE)很小。在使用闪光模式的所有协议中,与参考相比,PCD-CT的辐射剂量减少(16-75%)。尽管仅在序列模式下使用IQ20(22-44%)。对病人来说,ICC(所有ICC>0.98)和CACS的Bland-Altman分析均显示PCD-CT与参考文献的一致性较高,没有重新分类CACS类别(P=0.317)。根据我们的初步研究,PCD-CT在各种扫描协议中产生可重复且准确的CACS。Sn100kV,90kV,和120kV使用闪光模式在IQ20建议临床应用考虑准确性和辐射剂量。
    To validate the accuracy of coronary artery calcium score (CACS) using photon-counting detector (PCD) CT under various scanning settings and explore the optimized scanning settings considering both the accuracy and the radiation dose. A CACS phantom containing six hollow cylindrical hydroxyapatite calcifications of two sizes with three densities and 12 patients underwent CACS scans. For PCD-CT, two scanning modes (sequence and flash [high-pitch spiral mode]) and five tube voltages (90kV, 120kV, 140kV, Sn100kV, and Sn140kV) at different image quality (IQ) levels were set for phantom, and patients were scanned with 120kV at IQ19 using flash mode. All acquisitions from PCD-CT were reconstructed at 70keV. Acquisitions in sequence mode at 120kV on an energy-integrating detector CT (EID-CT) was used as the reference. Agatston, mass, and volume scores were calculated. The CACS from PCD-CT exhibited excellent agreements with the reference (all intraclass correlation coefficient [ICC] > 0.99). The root mean square error (RMSE) between the Agatston score acquired from PCD-CT and the reference (5.4-11.5) was small. A radiation dose reduction (16-75%) from PCD-CT compared with the reference was obtained in all protocols using flash mode, albeit with IQ20 only at sequence mode (22-44%). For the patients, ICC ( all ICC > 0.98) and Bland-Altman analysis of CACS all showed high agreements between PCD-CT and the reference, without reclassifying CACS categories(P = 0.317). PCD-CT yields repeatable and accurate CACS across diverse scanning protocols according to our pilot study. Sn100kV, 90kV, and 120kV using flash mode at IQ20 are recommended for clinical applications considering both accuracy and radiation dose.
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  • 文章类型: Journal Article
    目的:比较颞骨超高分辨率螺旋CT和超高分辨率容积CT的图像质量和辐射暴露。方法:使用6个尸体颞骨标本,使用以下CT重建和采集模式评估关键颞骨结构:超高分辨率的螺旋和单体积采集模式(0.25毫米切片厚度,10242矩阵),和超高分辨率的螺旋模式(0.25毫米切片厚度,20482矩阵)。两名观察者进行了5次先前描述的术前测量,测量的空气噪声和信噪比,和骨头的噪音,并以4分制对5个解剖结构的可视化进行了评级,对于每个重建模式。记录每次检查的辐射剂量暴露。结果:在任何重建和采集模式下,任何定量或定性测量之间都没有显着差异。与螺旋超高分辨率(分别为92.4±11.8HU和10.8±1.26)和螺旋超高分辨率(分别为91.1±10.7HU和10.9±1.39)模式(P<.002)相比,使用单体积模式(分别为115±13.1HU和8.37±0.91)的空气中噪声略有增加,信噪比降低螺旋采集的容积CT剂量指数为50.9mGy,单容积采集为29.8mGy(P<0.0001)。结论:与螺旋扫描相比,单体积超高分辨率采集模式可以减少辐射剂量暴露,而不会损害图像质量,但是在单音量模式下,空气中的信噪比略低,而螺旋超高分辨率和超高分辨率模式之间的图像质量没有差异。
    Purpose: To compare image quality and radiation exposure between super- and ultra-high-resolution helical and super-high-resolution volumetric CT of the temporal bone. Methods: Six cadaveric temporal bone specimens were used to evaluate key temporal bone structures using the following CT reconstruction and acquisition modes: helical and single-volume acquisition modes in super-high resolution (0.25-mm slice thickness, 10242 matrix), and helical mode in ultra-high resolution (0.25-mm slice thickness, 20482 matrix). Two observers performed 5 previously described preoperative measurements, measured noise and signal-to-noise ratios for air, and noise for bone, and rated the visualization of 5 anatomical structures on a 4-point scale, for each reconstruction mode. Radiation dose exposure was recorded for each examination. Results: There was no significant difference between any of the quantitative or qualitative measurements in any of the reconstruction and acquisition modes. There was a slight increase in noise and a decrease in signal-to-noise ratio in the air using the single-volume mode (115 ± 13.1 HU and 8.37 ± 0.91, respectively) compared to the helicoidal super-high-resolution (92.4 ± 11.8 HU and 10.8 ± 1.26, respectively) and helicoidal ultra-high-resolution (91.1 ± 10.7 HU and 10.9 ± 1.39, respectively) modes (P < .002). The volumic CT dose index was 50.9 mGy with helical acquisition and 29.8 mGy with single-volume acquisition mode (P < .0001). Conclusion: The single-volume super-high-resolution acquisition mode allows a reduction in radiation dose exposure without compromising image quality compared to helical scanning, but with a slightly lower signal-to-noise ratio in air with the single-volume mode, while there was no difference in image quality between the helical super- and ultra-high-resolution modes.
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  • 文章类型: Journal Article
    确定患有心外膜心脏可植入电子设备(CIED)的小儿先天性心脏病(CHD)患者是否从医学成像测试中接受了高累积有效剂量(CED)的电离辐射。
    我们比较了28例患有心外膜CIED(病例)的儿科CHD患者与40例患有非CIED的患者的手术年龄相匹配,性别,外科时代,和CHD诊断(对照)。我们对2006年至2022年间医学影像检查的辐射暴露进行了回顾性审查。使用国家癌症研究所辐射剂量测定工具计算计算机断层扫描(CT)和X射线照相术的辐射剂量。我们进行单因素分析以比较两组之间的CED。在case子组中,我们召集了专家审查,以裁定在没有aCIED的情况下,应该用磁共振成像(MRI)进行CT检查的患病率.与匹配的对照组相比,患有CIED的儿童(植入时的中位年龄为2.5岁)接受CED中位数显着更高(6.90vs.1.72mSv,P=0.0018)。在案例中,专家裁决显示,在没有aCIED的情况下,80%的CT检查将通过MRI进行.这导致了,平均而言,导线植入后CT的有效剂量(ED)增加了五倍。
    患有CIED的儿科CHD患者接受的CED是对照组的四倍。在没有电离辐射的情况下改善了对医学成像测试的访问,比如核磁共振,可能会使EDinCIED患者减少多达五倍。
    UNASSIGNED: To determine whether paediatric congenital heart disease (CHD) patients with epicardial cardiac implantable electronic devices (CIEDs) receive high cumulative effective doses (CEDs) of ionizing radiation from medical imaging tests.
    UNASSIGNED: We compared 28 paediatric CHD patients with epicardial CIEDs (cases) against 40 patients with no CIED matched by age at operation, sex, surgical era, and CHD diagnosis (controls). We performed a retrospective review of radiation exposure from medical imaging exams between 2006 and 2022. Radiation dose from computed tomography (CT) and X-ray radiography was calculated using the National Cancer Institute Radiation Dosimetry Tool. We performed univariate analysis to compare the CED between the two groups. In the case subgroup, we convened experts\' review to adjudicate the prevalence of CT exams that should have been performed with magnetic resonance imaging (MRI) in the absence of a CIED. Children (median age 2.5 years at implant) with CIEDs received significantly higher median CED compared with matched controls (6.90 vs. 1.72 mSv, P = 0.0018). In cases, expert adjudication showed that 80% of the CT exams would have been performed with MRI in the absence of a CIED. This resulted, on average, a five-fold increase in the effective dose (ED) from post-lead implant CTs.
    UNASSIGNED: Paediatric CHD patients with CIED received four times higher CED than matched controls. Improved access to medical imaging tests without ionizing radiation, such as MRI, could potentially reduce the ED in CIED patients by up to five times.
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  • 文章类型: Journal Article
    目的:展示使用50keV虚拟单色图像与深度学习图像重建(DLIR)在低剂量双能CT小肠造影(CTE)中的价值。
    方法:在这项前瞻性研究中,114名参与者(62%M;41.9±16岁)接受了双能CTE。使用标准剂量(噪声指数(NI):8)进行早期肠溶阶段,并在70keV和50keV下以40%强度的ASIR-V(ASIR-V40%)重建图像。肠溶后期使用低剂量(NI:12),并在50keV下用ASIR-V40%重建图像,和DLIR在中等(DLIR-M)和高强度(DLIR-H)。图像标准偏差(SD),信噪比(SNR),对比噪声比(CNR),计算了边缘上升斜率(ERS)。计算了27例克罗恩病患者的定量梳状体征评分。主观的噪音,图像对比度,由两名放射科医师盲目使用5分制对直肌动脉显示进行评分.
    结果:肠溶后期有效剂量减少了50%(P<0.001),达到3.26mSv。低剂量50keV-DLIR-H图像(SD:17.7±0.5HU)与标准剂量70keV-ASIR-V40%图像(SD:17.7±0.73HU)具有相似的图像噪声(P=0.97),但在信噪比较高(P<0.001)的情况下,CNR,ERS和定量梳状体征评分(分别为5.7±0.17、1.8±0.12、156.04±5.21和5.05±0.73)。此外,较低剂量的50keV-DLIR-H图像在直肌动脉可见性方面得分最高(4.27±0.6).
    结论:带有DLIR的双能CTE中的50keV图像提供了高质量的图像,辐射剂量减少50%.具有高对比度和密度分辨率的图像显着增强了克罗恩病的诊断信心,对于临床制定个性化治疗计划至关重要。
    OBJECTIVE: To demonstrate the value of using 50 keV virtual monochromatic images with deep learning image reconstruction (DLIR) in low-dose dual-energy CT enterography (CTE).
    METHODS: In this prospective study, 114 participants (62 % M; 41.9 ± 16 years) underwent dual-energy CTE. The early-enteric phase was performed using standard-dose (noise index (NI): 8) and images were reconstructed at 70 keV and 50 keV with 40 % strength ASIR-V (ASIR-V40%). The late-enteric phase used low-dose (NI: 12) and images were reconstructed at 50 keV with ASIR-V40%, and DLIR at medium (DLIR-M) and high strength (DLIR-H). Image standard deviation (SD), signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), edge-rise-slope (ERS) were computed. The quantitative comb sign score was calculated for the 27 patients with Crohn\'s disease. The subjective noise, image contrast, display of rectus artery were scored using a 5-point scale by two radiologists blindly.
    RESULTS: Effective dose was reduced by 50 % (P < 0.001) in the late-enteric phase to 3.26 mSv. The lower-dose 50 keV-DLIR-H images (SD:17.7 ± 0.5HU) had similar image noise (P = 0.97) as the standard-dose 70 keV-ASIR-V40% images (SD:17.7 ± 0.73HU), but with higher (P < 0.001) SNR, CNR, ERS and quantitative comb sign score (5.7 ± 0.17, 1.8 ± 0.12, 156.04 ± 5.21 and 5.05 ± 0.73, respectively). Furthermore, the lower-dose 50 keV-DLIR-H images obtained the highest score in the rectus artery visibility (4.27 ± 0.6).
    CONCLUSIONS: The 50 keV images in dual-energy CTE with DLIR provides high-quality images, with a 50 % reduction in radiation dose. Images with high contrast and density resolutions significantly enhance the diagnostic confidence of Crohn\'s disease and are essential for the clinical development of individualized treatment plans.
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  • 文章类型: Journal Article
    探讨计算机断层扫描(CT)引导下125I放射性粒子植入治疗放射性碘难治性分化型甲状腺癌(RAIR-DTC)淋巴结转移的可行性,并评估其安全性和有效性。验证计算机三维治疗计划系统(TPS)在剂量水平下采用125I粒子植入治疗淋巴结转移瘤的准确性。
    回顾性分析了2016年12月至2019年1月在北部战区总医院收治的42例RAIR-DTC和淋巴结转移患者。在这个分析中,医师利用术前CT图像设计使用TPS的术中计划.然后将术后计划的剂量学参数与术前计划进行比较。此外,这项研究检测了患者术后2,6和12个月时肿瘤大小和肿瘤相关标志物甲状腺球蛋白(Tg)值的变化.
    42例患者植入的125I放射性粒子数量为226个,平均每个病灶植入14.5个(范围2.0-30.0个)粒子。局部缓解率为97.62%(41/42),88.10%(37/42),术后2、6和12个月85.71%(36/42),分别。治疗后2,6,12个月病灶体积分别为(4.44±1.57)cm3,(4.20±1.70)cm3,(4.23±1.77)cm3,分别,较术前基线水平(6.87±1.67)cm3明显下降(t值:9.466、9.923、7.566,均P<0.05)。Tg为15.95(5.45,73.93)μg/L,8.90(2.20,39.21)μg/L,治疗后2、6、12个月分别为6.00(1.93、14.18)μg/L,分别,显著低于术前基线水平53.50(20.94,222.92)μg/L(Z值:-5.258,-5.009,-4.987,均P<0.001)。术后,在95.23%(40/42)的患者中,给予90%的GTV(D90)略低于处方剂量,但差异无统计学意义[(12,378.8±3,182.0),(12,497.8±1,686.4)cGy;t=0.251,P>0.05],和术后剂量参数传递到100%的总肿瘤体积(GTV)(D100)(6,881.5±1,381.8)cGy,GTV接受150%处方剂量的体积百分比(V150)(58.5±18.40)%低于术前计划D100(8,085.8±2,330.0)cGy,V150(66.5±17.70)%;t值=8.913和3.032,均P<0.05;其余指标与术前计划无显著差异(植入颗粒数的差异,规划目标体积(PTV),接受100%处方剂量(V100)的GTV的体积百分比,均一性指数(HI)无统计学意义(t/Z=-0.593、-1.604、-0.663,均P>0.05)。
    参考TPS术前计划,125I粒子植入治疗RAIR-DTC淋巴结转移能达到预期的剂量分布,确保精确的短期局部肿瘤控制疗效。
    UNASSIGNED: To investigate the feasibility and evaluate the safety and effectiveness of Computed Tomography (CT) guided125I radioactive particle implantation for treating lymph node metastases in radioiodine-refractory differentiated thyroid cancer (RAIR-DTC). To verify the accuracy of the computerized three-dimensional treatment planning system (TPS) in treating lymph node metastasis using125I particle implantation at the dosimetric level.
    UNASSIGNED: A retrospective analysis was conducted on 42 patients with RAIR-DTC and lymph node metastases who were admitted to the General Hospital of the Northern Theater Command between December 2016 and January 2019. During this analysis, physicians utilized preoperative CT images to design an intraoperative plan using TPS. The dosimetric parameters of the postoperative plan were then compared to the preoperative plan. Additionally, this study examined the changes in tumor size and tumor-related marker Thyroglobulin (Tg) values in patients at 2, 6, and 12 months after the operation.
    UNASSIGNED: The number of125I radioactive particles implanted in 42 patients was 226, with an average of 14.5 (range 2.0-30.0) particles implanted per lesion. The local remission rates were 97.62% (41/42), 88.10% (37/42), and 85.71% (36/42) at 2, 6, and 12 months postoperatively, respectively. The volume of the lesions was (4.44 ± 1.57) cm3, (4.20 ± 1.70) cm3, and (4.23 ± 1.77) cm3at 2, 6, and 12 months after treatment, respectively, which significantly decreased from the preoperative baseline level of (6.87 ± 1.67) cm3(t-values: 9.466, 9.923, 7.566, all P<0.05). The Tg levels were 15.95 (5.45, 73.93) μg/L, 8.90 (2.20, 39.21) μg/L, and 6.00 (1.93, 14.18) μg/L at 2, 6, and 12 months after treatment, respectively, which were significantly lower than the preoperative baseline levels of 53.50 (20.94, 222.92) μg/L (Z values: -5.258, -5.009, -4.987, all P < 0.001). Postoperatively, Delivered to 90% of the GTV(D90) was slightly lower than the prescribed dose in 95.23% (40/42) of patients, but the difference was not statistically significant [(12,378.8 ± 3,182.0), (12,497.8 ± 1,686.4) cGy; t=0.251, P>0.05], and postoperative dose parameters delivered to 100% of the gross tumor volume (GTV)(D100) (6,881.5 ± 1,381.8) cGy, the volume percentages of GTV receiving 150% of the prescribed dose(V150) (58.5 ± 18.40)%) were lower than the preoperative plan D100 (8,085.8 ± 2,330.0) cGy, V150 (66.5 ± 17.70)%; t-value=8.913 and 3.032, both P<0.05; the remaining indicators were not significantly different from the preoperative plan (the differences in the number of implanted particles, Planning Target Volume(PTV), the volume percentages of GTV receiving 100% of the prescribed dose(V100), Homogeneity Index(HI)were not statistically significant (t/Z = -0.593, -1.604, 1.493, -0.663, all P>0.05).
    UNASSIGNED: Referring to the TPS preoperative plan, the125I particle implantation therapy for RAIR-DTC lymph node metastasis can achieve the expected dose distribution, ensuring precise short-term local tumor control efficacy.
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  • 文章类型: Journal Article
    目的:与基于匹配能量积分探测器(EID)的单能量CTPA相比,使用光子计数探测器(PCD)CT评估具有自由呼吸技术的超高螺距CT肺动脉造影(CTPA)诊断肺栓塞的图像质量和辐射剂量。
    方法:在第三代双源EID-CT上对51个PCD-CTPA进行了前瞻性比较。CTPAs是通过具有自由呼吸技术的超高螺距方案获得的(40mL造影剂,间距3.2)在140kV(PCD)和70-100kV(EID)。从光谱PCD-CTPAs重建碘图谱。CTPAs和碘图的图像质量由三名放射科医生独立评估。此外,肺动脉内的CT衰减数以及信噪比和对比噪声比(SNR,CNR)进行了比较。比较施用的辐射剂量。
    结果:PCD组的CT衰减较高(均P<0.05)。PCD-CTPAs大叶肺动脉CNR和SNR较高(P<0.05),而肺动脉干内无差异(P>0.05)。PCD-CTPA的图像质量被所有读者评为最佳(96.1%的PCD-CTPA与50.9%的EID-CTPAs)。PCD-CT没有产生非诊断扫描与三个非诊断性(5.9%)EID-CTPA。PCD-CT的辐射剂量低于EID-CT(有效剂量1.33±0.47vs.1.80±0.82mSv;所有P<0.05)。
    结论:采用PCD-CT自由呼吸技术的超高螺距CTPA可获得优异的图像质量,同时显著降低辐射剂量和完整的光谱信息。随着超高的音调,只有PCD-CTPA能够重建包含额外功能信息的碘图谱.
    OBJECTIVE: To assess image quality and radiation dose of ultra-high-pitch CT pulmonary angiography (CTPA) with free-breathing technique for diagnosis of pulmonary embolism using a photon-counting detector (PCD) CT compared to matched energy-integrating detector (EID)-based single-energy CTPA.
    METHODS: Fifty-one PCD-CTPAs were prospectively compared to 51 CTPAs on a third-generation dual-source EID-CT. CTPAs were acquired with an ultra-high-pitch protocol with free-breathing technique (40 mL contrast medium, pitch 3.2) at 140 kV (PCD) and 70-100 kV (EID). Iodine maps were reconstructed from spectral PCD-CTPAs. Image quality of CTPAs and iodine maps was assessed independently by three radiologists. Additionally, CT attenuation numbers within pulmonary arteries as well as signal-to-noise and contrast-to-noise ratios (SNR, CNR) were compared. Administered radiation dose was compared.
    RESULTS: CT attenuation was higher in the PCD-group (all P < 0.05). CNR and SNR were higher in lobar pulmonary arteries in PCD-CTPAs (P < 0.05), whereas no difference was ascertained within the pulmonary trunk (P > 0.05). Image quality of PCD-CTPA was rated best by all readers (excellent/good image quality in 96.1% of PCD-CTPAs vs. 50.9% of EID-CTPAs). PCD-CT produced no non-diagnostic scans vs. three non-diagnostic (5.9%) EID-CTPAs. Radiation dose was lower with PCD-CT than with EID-CT (effective dose 1.33 ± 0.47 vs. 1.80 ± 0.82 mSv; all P < 0.05).
    CONCLUSIONS: Ultra-high-pitch CTPA with free-breathing technique with PCD-CT allows for superior image quality with significantly reduced radiation dose and full spectral information. With the ultra-high pitch, only PCD-CTPA enables reconstruction of iodine maps containing additional functional information.
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  • 文章类型: Journal Article
    目的:为了评估使用光子计数探测器CT(PCD-CT)与双源相比获得的肺灌注成像的质量,双能量CT(DECT)。
    方法:使用(a)用于DS-CT(组1):准直:64×0.6×2mm;间距:0.55;(b)用于PCD-CT(组2):准直:144×0.4mm;间距:1.5;单源采集。两组的注射方案相似,通过减去高能和低能虚拟单能量图像来重建灌注图像。
    结果:与第1组相比,第2组检查显示:(a)数据采集的持续时间较短(0.93±0.1svs3.98±0.35s;p<0.0001);(b)剂量长度乘积显着降低(172.6±55.14vs339.4±75.64mGy·cm;p<0.0001);以及(c)较高的客观噪声水平。在灌注图像上:(a)衰减的平均水平没有差异(p=0.05),第2组的主观图像噪声较少(p=0.049);(b)两组之间的裂隙可视化评分分布不同(p<0.0001),第2组中明显描绘的裂隙比例较高(n=60;84.5%vsn=26;26.6%),在第2组检查中,轻度运动伪影的评分<7.2%(n
    结论:PCD-CT采集在较低的辐射剂量下提供了相似的形态学图像质量和优异的灌注成像。
    结论:在较低辐射剂量下灌注图像整体质量的提高为肺灌注成像在临床实践中的更广泛应用打开了大门。
    结论:使用PCD-CT进行数据采集的速度是轻度运动伪影的原因。在PCD-CT灌注图像上描绘了清晰描绘的裂缝。获得高质量的灌注成像,剂量减少52%。
    OBJECTIVE: To evaluate the quality of lung perfusion imaging obtained with photon-counting-detector CT (PCD-CT) in comparison with dual-source, dual-energy CT (DECT).
    METHODS: Seventy-one consecutive patients scanned with PCD-CT were compared to a paired population scanned with dual-energy on a 3rd-generation DS-CT scanner using (a) for DS-CT (Group 1): collimation: 64 × 0.6 × 2 mm; pitch: 0.55; (b) for PCD-CT (Group 2): collimation: 144 × 0.4 mm; pitch: 1.5; single-source acquisition. The injection protocol was similar in both groups with the reconstruction of perfusion images by subtraction of high- and low-energy virtual monoenergetic images.
    RESULTS: Compared to Group 1, Group 2 examinations showed: (a) a shorter duration of data acquisition (0.93 ± 0.1 s vs 3.98 ± 0.35 s; p < 0.0001); (b) a significantly lower dose-length-product (172.6 ± 55.14 vs 339.4 ± 75.64 mGy·cm; p < 0.0001); and (c) a higher level of objective noise (p < 0.0001) on mediastinal images. On perfusion images: (a) the mean level of attenuation did not differ (p = 0.05) with less subjective image noise in Group 2 (p = 0.049); (b) the distribution of scores of fissure visualization differed between the 2 groups (p < 0.0001) with a higher proportion of fissures sharply delineated in Group 2 (n = 60; 84.5% vs n = 26; 26.6%); (c) the rating of cardiac motion artifacts differed between the 2 groups (p < 0.0001) with a predominance of examinations rated with mild artifacts in Group 2 (n = 69; 97.2%) while the most Group 1 examinations showed moderate artifacts (n = 52; 73.2%).
    CONCLUSIONS: PCD-CT acquisitions provided similar morphologic image quality and superior perfusion imaging at lower radiation doses.
    CONCLUSIONS: The improvement in the overall quality of perfusion images at lower radiation doses opens the door for wider applications of lung perfusion imaging in clinical practice.
    CONCLUSIONS: The speed of data acquisition with PCD-CT accounts for mild motion artifacts. Sharply delineated fissures are depicted on PCD-CT perfusion images. High-quality perfusion imaging was obtained with a 52% dose reduction.
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