简介:全球,癌症是导致死亡的主要原因,结直肠肿瘤在全球发病率和死亡率方面排名第三。患者面临疾病和治疗特定的影响,这会显著影响他们的生活质量(QoL)。目的:本研究旨在提出一种方法来测量复杂结直肠癌(CRC)患者的住院和长期QoL。材料和方法:多中心前瞻性观察队列研究。结果:QoL是一个多维概念,包括物理标准,心理,情感,和患者感知的社会功能。定期评估QoL提供了可测量和客观的工具,可以在适当的时间进行干预,以减少CRC患者的生命损失和残疾年份。然而,一个结构化和功能性的系统需要专门和共同的机构努力。使用该协议的初步研究包括69名患者,65.12+-10.92年,M:F比率=56.5:43.5%。外科手术是右半结肠切除术,左结肠切除术,横结肠切除术,乙状结肠切除术,全结肠切除术,直肠切除术,结直肠切除伴造口(回肠造口术或结肠造口术)占21.7%,11.6%,2.9%,11.6%,1.4%,23.2%,以及27.5%的病例,分别。平均全球健康状况评分,症状评分,功能评分分别为82.36+-18.60、11.89+-10.27和86.27、74.50-94.11。结论:CRC的诊断对患者的生理和心理状态有重要影响,参与的医疗团队和医疗保健系统应集中力量改善整个治疗途径的QoL。
Introduction: Globally, cancer is the leading cause of mortality, with colorectal neoplasia ranking third in terms of incidence and mortality worldwide. Patients face disease- and treatment-specific impacts, which can significantly influence their quality of life (QoL). Aim: This study aimed to propose a protocol to measure in-hospital and long-term QoL in patients with complicated colorectal cancer (CRC). Material and Methods: multicenter prospective observational cohort study. Results: QoL is a multidimensional concept that includes criteria for physical, mental, emotional, and social functionality as perceived by the patient. Periodically evaluating QoL offers measurable and objective tools to intervene at the appropriate time to decrease the Years of Life Lost and Years Lived with Disabilities for CRC patients. However, a structured and functional system requires dedicated and common institutional effort. A pilot study using this protocol included 69 patients, 65.12+-10.92 years, M:F ratio = 56.5:43.5%. Surgical procedure was right hemicolectomy, left colectomy, transverse colectomy, sigmoidectomy, total colectomy, rectal resection, and colorectal resection with stoma (ileostomy or colostomy) in 21.7%, 11.6%, 2.9%, 11.6%, 1.4%, 23.2%, and 27.5% of the cases, respectively. The mean Global Health Status Score, Symptom Score, and Functional Score was 82.36+-18.60, 11.89+-10.27, and 86.27, 74.50-94.11, respectively. Conclusions: CRC diagnosis has major effects on patients physical and psychological status, and concentrated efforts should be made by the involved medical team and healthcare systems to improve QoL throughout the treatment pathway.