杂环化合物的化学一直是研究的主题。一些五元杂环化合物由于其不同类型的药理作用而成为广泛研究的主题。五元含氮杂环化合物吡唑,吡唑啉,吡唑啉酮和吡唑啉酮衍生物由于其不同的治疗活性而在医学和农业化学领域中具有很大的兴趣。各种取代的吡唑,吡唑啉,和吡唑啉酮化合物表现出不同的药理作用,如抗微生物,抗炎,抗结核,抗真菌,抗疟疾,反糖尿病,利尿剂,抗抑郁药,抗惊厥药,抗氧化剂,抗利什曼,抗糖尿病药,和抗病毒,等。近几十年来,许多吡唑的合成,吡唑啉,和吡唑啉酮衍生物通过不同的合成方法以及对其化学和生物学行为的研究变得越来越重要。本文对吡唑的合成方法,吡唑啉,和吡唑啉酮衍生物,具有显著的生物学特性和多种应用。
The chemistry of heterocyclic compounds has been a topic of research interest. Some five-membered heterocyclic compounds have been the subject of extensive research due to their different types of pharmacological effects. The five-membered nitrogen-containing heterocyclic compounds pyrazole,
pyrazoline, and pyrazolone derivatives have a lot of interest in the fields of medical and agricultural chemistry due to their diverse spectrum of therapeutic activities. Various substituted pyrazole,
pyrazoline, and pyrazolone compounds exhibited diverse pharmacological effects like Anti-microbial, anti-inflammatory, anti-tubercular, anti-fungal, anti-malarial, anti-diabetic, diuretic, anti-depressant, anticonvulsant, antioxidant, anti-leishmanial, antidiabetic, and antiviral, etc. In recent decades, the synthesis of numerous pyrazole,
pyrazoline, and pyrazolone derivatives by different synthetic methods as well as research into their chemical and biological behavior have become more important. This review focuses on synthetic methods of the pyrazole,
pyrazoline, and pyrazolone derivatives, which have significant biological properties and a variety of applications.